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Query: [S] COG5501 Predicted secreted protein, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKLILALIPVTLTASLALAEPEKPNNPLADGTTWRDLKGDVVGEAAILDGSALFSVTAPYRANDAATVPVTIEQTDAAADPIESLKLVIDENPAPVAAEIRFGPAMAPLKFETRVRVNQYSNIRAIAETPRGIFMHGRFVKASGGCSAPATKDPVAALKDMGEMRLKLFGGKGEVQKARREAQIMIRHPNYSGLQRDQITQLFVSAKFITELVVKQGDELLFALDGGISISENPVFRFSYTDNGAPDFTVHAVDTDGNVFDRVLPKTPPALast
1 -8.380sp|Q5VST9|OBSCN_HUMAN Obscurin OS=Homo sapiens GN=OBSCN PE=1 SV=3  ali   10  1...........................................................ESTTDEGQLPQVVDLQVAPGTRLAKFQLKVKGYPAPRLYHIRMTDKKILHTLEISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSITFSVKVEVPTVHWLREEAERGVLWIGPDTPGYTVASSA------------QQHSLVLLDVGRQHQGTYTCIASNAAGQA-LCSASLHVSG 218
2 -8.150sp|P01024|CO3_HUMAN(removed signalp:1-22) Complement C3 OS=Homo sapiens GN=C3 PE=1 SV=2  ali   11  1..................................................SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDFPGKKLVLSSEKTVLTPATNHMGNEFKSEKGRNKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTVMVNIENPNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKE-PSFEVIVEPTEK-EVTITARFLYGKKVEGTAFVIFG. 252
3 -7.830sp|Q14CZ8|HECAM_HUMAN(removed signalp:1-33) Hepatocyte cell adhesion molecule OS=Homo sapiens GN=HEPACAM PE=1 SV=1  ali follow..  5  1.....................................................VNITSPVHGTVGKSALLSVQYSSTSSD-RPVVKWQLKRDKPVTVVQSIGTEVIGTPDYRDRIRLFENGSLLLLQLADEGTYEVE--ISITDDTFTGEKTINLTVDVPISRPQVLVASTTVLELSEAFTLNCSHEGTKPS-------------------YTWLKDGKPLLNDSRMLLSPDQKVLTIRVLMEDDDLYSCMVENPISQGRSLPVKITV.. 202
4 -7.630sp|P54296|MYOM2_HUMAN Myomesin-2 OS=Homo sapiens GN=MYOM2 PE=2 SV=2  ali   12  2........................................................RAPEILVRLRSHTVWERMSV-------KLCFTVQGFPTPVVQKYRIESNYGVHTLEINADFDDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSLEKFGVTFRREGETVTLKCTMLTPDLKRVQ--------------PRAEWYRDDVLLKESKWTKMFFGEGQASLSFSKDDEGLYTLRIVSRGGVS-DHSAFLFVRD 224
5 -7.490sp|O43451|MGA_HUMAN(removed signalp:1-35) Maltase-glucoamylase, intestinal OS=Homo sapiens GN=MGAM PE=1 SV=5  ali   11  3.......................................DYETGSQVRWRKQKVEMELP-HLRGGYIFPTQQPNTTTLASRKNPLGLIIALDENKEAK--TKDTVANKVYLLCEFSVTQNRLEVNISQSTYKDPNNLAFNEIKILGTEEPSNVTVKHNGVPSQTSPTVTYDSNLKVAIITDIDLLLGYPDENGASAEASNSSGVPFCYFVNDLYSVSDVQYNSHGATADISLKNPLRLDVTYHKNEMLQFKIYDPNKNRYEVPVPLNIP. 286
6 -7.400sp|Q3KPI0|CEA21_HUMAN(removed signalp:1-34) Carcinoembryonic antigen-related cell adhesion molecule 21 OS=Homo sapiens GN=CEACAM21 PE=2 SV=2  ali follow..  7  2.....................................................LFIASPFEVAEGENVHLSVVYL---PENLYSYGWYKGKTVEPNQLIAAYVIDTHVPAYSGRETISPSGDLHFVTLEDTGYYT----LQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCHTNNTGTS-------------------FQWIFNNQRLQVTKRMKLSWFNHMLTIPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVK. 199
7 -7.400sp|Q15772|SPEG_HUMAN Striated muscle preferentially expressed protein kinase OS=Homo sapiens GN=SPEG PE=1 SV=4  ali   10  1................................................TCSARLTVRAPLFTRLLEDVEVLEGRAA-------RFDCKISGTPPPVVTNLRLRQDGGLHSLHIHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEELRPLQDLEVGLAKEAMLECQV-------------TGLPYP-----TISWFHNGHRIQSSDDRRMTQYRDVHRLVFPPQHAGVYKSVIANKLGKA-ACYAHLYVTD 229
8 -7.360sp|Q0JRZ9|FCHO2_HUMAN FCH domain only protein 2 OS=Homo sapiens GN=FCHO2 PE=1 SV=2  ali   11  57.......................................................LKYQVSSNGIQSTPLNLATYWKCSASTTDLRVDYKYNPEAMVAPSVLS--------NIQVVVPVDGGVTNMQSLPPAIWNAEQMKAF-------SSISEKSENGGSGSLRAKFDLSEGPSKPTTLAVQFLSEGSTLSGVDFELVGTGYRLSLIKKRFA---TGRYLADC.............................................. 210
9 -7.280sp|Q8WZ42|TITIN_HUMAN Titin OS=Homo sapiens GN=TTN PE=1 SV=2  ali   8  51........................................................QKPFFKKRFGPAHFECRLTPIGDPTMV-VEWLHDGKPLEAANRLRMINEFGYCSLDYGAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSLVEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARF--KVNWYLNGQLIRKSK-RFRVRYDGIHYLDIVSYDTGEVKVTAENPEGVI-EHKVKLEIQQ 281
10 -7.230sp|O95932|TGM3L_HUMAN Protein-glutamine gamma-glutamyltransferase 6 OS=Homo sapiens GN=TGM6 PE=2 SV=3  ali   5  38............................................EPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRA-QRVRVNLSGATILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMCLVTKGEKLLVEKDITLEDFITIKVLGPAMVGVAVTVEVTVVNPLIE----------------VKDCALMVEGSGLLQEQLSIDVPERASVQFDITPSKSGQLQVDLVSPHFPDIKGFVIVHVA. 253
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Pio F, Pawlowski K, Godzik A. Saturated BLAST: an automated multiple intermediate sequence search used to detect distant homology. Bioinformatics. 2000 Dec;16(12):1105-10.