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Query: [W] KOG3658 Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases, from VFDB

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSSPIRNRLQLVVTLIFCLFFENVNGLNNFIDNFETLNYRATHVANQVTRRKRSIDSAASHYQEPIGFRFNAYNRTFHVQLHPIDDSLFHEDHMSDVDGGYADIKPSHFLYEGYLKDDPNSHVHGSVFDGVFEGHIQTGEGRRYSIDKAAKYFERDDRPTQYHSIIYRDDEINHRKWRVKRDAENLSEQMQGCGFSSRVRREMTDVQNSGESTDFFTNYMTMGGRSKRANTLRDHDGLYFVRTCSLYMQADHKLYEHIRMKEGNNDPIRTREEIVSLFYNHIKAVNEIYEGTNFNGIKGLHFVIQRTSIYTPDSCDRGRAKTDSDNPFCEENVDVSNFLNLNSQRNHSAFCLAYALTFRDFVGGTLGLAWVASPQFNTAGGICQVHQRYNEGSRGWVYRSLNTGIVTLVNYGNRVPARVSQLTLAHEIGHNFGSPHDFPAECQPGLPDGNFIMFASATSGDKPNNGKFSPCSVKNISAVLAVVLKSMPVDPTRNASPVGIGKRNCFQERTSAFCGNQIYEPGEECDCGFSQADCDQMGDKCCVPHEARGNGGPGPCKRKPGAQCSPSQGYCCNPDTCSLHGKNEEKICRQESECSNLQTCDGRNAQCPVSPPKHDGIPCQDSTKVCSSGQCNGSVCAMFGLEDCFLTEGKADELCFLACIKDGKCTSSVHLPEFSANRTNFLQNMRKDKPGLILHPGSPCNNYKGYCDIFRKCRSVDANGPLARLKNLLFNKRTIETLTQWAQDNWWVVGVGGLVFLVIMALFVKCCAVHTPSTNPNKPPALNIYQTLTRPGTLIRQHRQRHRAAAGSVPPGPGAQPRSGAASAPSRTTPSARPSAPPLVAPQVAVAVPPGVVGPPIPLIATHPGSSSSTPAVIVLEPPPPYTAADPGSAMGGPRRGHRKNKRQTSSDAAGSSGNGGKKKGKLast
1 -80.300sp|P78536|ADA17_HUMAN(removed signalp:1-17) Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1  ali   30  8......................................................................................................................................................................................................................................................................................................................................................IAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYY---SPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECADQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSN------------------KVCGNSRVDEGEECDPGIMYL----NNDTCCNS----------DCTLKEGVQCSDRNSPCC--KNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVC-LDLGKCKDGKCIPFCEREQQLESCAC--NETDNSCKVCCRDLSG.................................................................................................................................................................................................................................................................. 292
2 -77.600sp|O14672|ADA10_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 10 OS=Homo sapiens GN=ADAM10 PE=1 SV=1  ali   46  1....................................................................................................................................................................................................................................................................................................................................................................TDRDFDDGVLGLAWVGAPSG-SSGGICEKSKLYSDGKK----KSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPQKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESGQ------------------PICGNGMVEQGEECDCGYSDQ----CKDECCFDANQ---PEGRKCKLKPGKQCSPSQGPCCT-AQCAFKSKSEKCR--DDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDDKELCHVCCMKKMDPSTC.............................................................................................................................................................................................................................................................. 289
3 -71.800sp|O15204|ADEC1_HUMAN(removed signalp:1-30) ADAM DEC1 OS=Homo sapiens GN=ADAMDEC1 PE=1 SV=2  ali follow..  16  6...........................TPELTLHEIVCPKKLHILHKRKNNQTEKHGKEERYEPEVQYQMILNGEEIILSLQKTKHLLGPDYTETLYSPRGEEITTEHCYYKGNILNEKNSVASISTCDG-LRGYFTHHHQRYQIKP---------KSTDEKEHAVFTSNQEEQDPANHTCGVKSTDGK------------------------------QGPIRISRSLKSPEKEDFLRAQKYIDLYLVLDNAFYKNYNEN---------LTLIRSFVFDVMNLLNVIYNTI------DVQVALVGMEIWSDGD----KIKVVPSASTTFDNFLRWHSSNLGKKIHDH----AQLLSGISFNNRRVGLAASNSLCSPSSVAVIEAKKK---------------------------NNVALVGVMSHELGHVLGMPDVPFN---TKCPSGSCVMNQYL---SSKFPKDFSTSCRAHFERYLLSQKPKCLLQAPIPTNIM-----------TTPVCGNHLLEVGEDCDCGSPKE----CTNLCC---------EALTCKLKPGTDCG--GDAPN--HTTE........................................................................................................................................................................................................................................................................................................................................................ 440
4 -70.200sp|O75077|ADA23_HUMAN Disintegrin and metalloproteinase domain-containing protein 23 OS=Homo sapiens GN=ADAM23 PE=1 SV=1  ali   21  1...................................................................................................................................................................................................................................................LELMIVNDHKTYKKHRSS---------HAHTNNFAKSVVNLVDSIYKEQ-----LNTRVVLVAVETWTEKD----QIDITTNPVQMLHEFSKYR------QRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGL----------------------------PMAVAQVLSQSLAQNLGIQWE-PSSRKPKCDCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPT-------------KLFEPTECGNGYVEAGEECDCGFHVE----CYGLCCK-----------KCSLSNGAHCS--DGPCCNNTSCLFQPRGYECR-DAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCY....................................................................................................................................................................................................................................................................................................... 300
5 -68.800sp|O14672|ADA10_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 10 OS=Homo sapiens GN=ADAM10 PE=1 SV=1  ali   37  2.............................................................................................................................................................QGGCADHSVFERMRKYQMT----------------------------------GVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYG----------TREAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTAD------EKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICEK-----SKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGTECTPGKENGNYIMYARATSGDKLNNNKFSLCSIRNISQVLEKKRNNCFVESG------------------QPICGNGMVEQG................................................................................................................................................................................................................................................................................................................................................................................................................ 300
6 -65.400sp|Q9P0K1|ADA22_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 22 OS=Homo sapiens GN=ADAM22 PE=1 SV=1  ali   21  1...............................................................................................................................................................................................................................................................................................................................................................AVHLFSGSQFESSRSGAAYIGGICSLLKGGGVNEFGKTD----------------------------LMAVTLAQSLAHNIGIISDKRKECKCEDTWSGCIMGDTGYYL----PKKFTQCNIEEYHDFLNSGGGACLFNKPS-------------KLLDPPECGNGFIETGEECDCGTPAE---CVLEGAE---------CCKKCTLTQDSQCS--DGLCC--KKCKFQPMGTVCR-EAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQGICFGGRCKTRD------RQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCG-KDKDTWIQCNKRDVLCGYLL----CTNIG.......................................................................................................................................................................................................................... 284
7 -64.500sp|Q99965|ADAM2_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 2 OS=Homo sapiens GN=ADAM2 PE=1 SV=2  ali   20  2.......................................................................................................................................................................................................................................QSVEPQQDFAKYIEMHVIVEKQLYNHMGSD---------TTVVAQKVFQLIGLTNAIFVSF------NITIILSSLELWIDEN----KIATTGEANELLHTFLRWKTSYLVLRPH----DVAFLLVYR-EKSNYVGATFQGKMCDANYAGGVVL-------------------------HPRTISLESLAVILAQLLSLSMGITYDDINKCQC--SGAVCIMNPEAIH--FSGVKIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFF----------KQQAVCGNAKLEAGEECDCGTEQD-CALIGETCC---------DIATCRFKAGSNCA--EGPCC--ENCLFMSKERMCR-PSFEECDLPEYCNGSSASCP.......................................................................................................................................................................................................................................................................................................................... 300
8 -64.000sp|Q9H013|ADA19_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 19 OS=Homo sapiens GN=ADAM19 PE=1 SV=3  ali   23  3........................................................................................................................................................................................................................................................................................................................................................................................................................VNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAAT---GHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLY-----------GGRRCGNGYLEDGEECDCGEEEE----CNNPCC---------NASNCTLRPGAECA--HGSCC--HQCKLLAPGTLCR-EQARQCDLPEFCTGKSPHCPTNFYQMDGTPCEGGQAYCYNGMCLTYQ------EQCQQLWGPGARPAPDLCFEKVNVAGDTFGNCGKDMNGEHRKCNMRDAKCGKIQ----CQSSEARPLESNQCRGTHVY........................................................................................................................................................................................................... 286
9 -63.500sp|O75078|ADA11_HUMAN(removed signalp:1-23) Disintegrin and metalloproteinase domain-containing protein 11 OS=Homo sapiens GN=ADAM11 PE=2 SV=3  ali   23  2..............................................................................................................................................................................................................................................................................................................................................................DATHLFSGRTFQSTSSGAAYVGGICSLSHGGGVNEYGN----------------------------MGAMAVTLAQTLGQNLGMMWNKHRDCKCPDIWLGCIMEDTGFYL----PRKFSRCSIDEYNQFLQEGGGSCLFNKPL-------------KLLDPPECGNGFVEAGEECDCGSVQE---CSRAGGN---------CCKKCTLTHDAMCS--DGLCC--RRCKYEPRGVSCR-EAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRD------RQCQVLWGHA--AADRFCYEKLNVEGTERGSCG-RKGSGWVQCSKQDVLCGFLL----CVNIS.......................................................................................................................................................................................................................... 284
10 -63.400sp|Q9Y3Q7|ADA18_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 18 OS=Homo sapiens GN=ADAM18 PE=2 SV=1  ali   18  2.................................................................................................................................................................................................................................KVPLNSQIKNLSKLLPQYLEIYIIVEKALYDYMGSE---------MMAVTQKIVQVIGLVNTMFTQF------KLTVILSSLELWSNEN----QISTSGDADDILQRFLAWKRDYLILRPH----DIAYLLVYRKH-PKYVGATFPGTVCNKSYDAGIAMYP-------------------------DAIGLEGFSVIIAQLLGLNVGLTYDDITQCFCLRATCIMNHEAVSASG----RKIFSNCSMHDYRYFVSKFETKCLQKLSNLQP----------LHQNQPVCGNGILESNEECDCGNKNE---CQFKKCC---------DYNTCKLKGSVKCG--SGPCCT-SKCELSIAGTPCRKSIDPECDFTEYCNG................................................................................................................................................................................................................................................................................................................................ 300
11 -63.300sp|Q9BZ11|ADA33_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 33 OS=Homo sapiens GN=ADAM33 PE=1 SV=2  ali   27  1.........................................................................................................................................................................................................................................................................................................................................................................................................................STDHSELPIGAAATMAHEIGHSLGLSHDPDGCVEAAAESGGCVMAAAT---GHPFPRVFSACSRRQLRAFFRKGGGACLSNAPDPGLPV-----------PPALCGNGFVEAGEECDCGPGQE----CRDLCC---------FAHNCSLRPGAQCA--HGDCC--VRCLLKPAGALCR-QAMGDCDLPEFCTGTSSHCPPDVYLLDGSPCARGSGYCWDGACPTLE------QQCQQLWGPGSHPAPEACFQVVNSAGDAHGNCGQDSEGHFLPCAGRDALCGKLQ----CQGGK.......................................................................................................................................................................................................................... 254
12 -63.300sp|Q8TC27|ADA32_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 32 OS=Homo sapiens GN=ADAM32 PE=1 SV=2  ali   17  1..............................................................................................................................................................................................................................DDNIFISEKSEPAVPDLFPLYLEMHIVVDKTLYDYWGSD---------SMIVTNKVIEIVGLANSMFTQF------KVTIVLSSLELWSDEN----KISTVGEADELLQKFLEWKQSYLNLRPH----DIAYLLIYMDY-PRYLGAVFPGTMCITRYSAGVALYP-------------------------KEITLEAFAVIVTQMLALSLGISYDDPKKCQC--SESTCIMNPEVVQ--SNGVKTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKS-----------PKPVCGNGRLEGNEICDCGTEAQ---CGPASCC---------DFRTCVLKDGAKCY--KGLCC--KDCQILQSGVECRPKAHPECDIAENCNG................................................................................................................................................................................................................................................................................................................................ 300
13 -62.900sp|O43184|ADA12_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 12 OS=Homo sapiens GN=ADAM12 PE=1 SV=3  ali   24  2.....................................................................................................................................................................................................................................................................................................................................................................................................................SGGIVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDSCQMAVEKGGCIMNAST---GYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESF-----------GGQKCGNRFVEEGEECDCGEPEE----CMNRCC---------NATTCTLKPDAVCA--HGLCC--EDCQLKPAGTACR-DSSNSCDLPEFCTGASPHCPANVYLHDGHSCQDVDGYCYNGICQTHE------QQCVTLWGPGAKPAPGICFERVNSAGDPYGNCGKVSKSSFAKCEMRDAKCGKIQ-----------------CQGGASRPVIGTNAVSIETNIPLQQGGRILC................................................................................................................................................................................... 287
14 -62.900sp|Q8TC27|ADA32_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 32 OS=Homo sapiens GN=ADAM32 PE=1 SV=2  ali   18  1.....................................................................................................................................................................................................................................................................................................................................................................................................................................VIVTQMLALSLGISYDDPKKCQC--SESTCIMNPEVVQ--SNGVKTFSSCSLRSFQNFISNVGVKCLQNKPQMQKKS-----------PKPVCGNGRLEGNEICDCGTEAQ---CGPASCC---------DFRTCVLKDGAKCY--KGLCC--KDCQILQSGVECRPKAHPECDIAENCNGTSPECGPDITLINGLSCKNNKFICYDGDCHDLD------ARCESVFGKGSRNAPFACYEEIQSQSDRFGNCGRDRNNKYVFCGWRNLICGRLVCGSQCDI--GRVCVNRECVES.............................................................................................................................................................................................................. 300
15 -61.500sp|Q9H2U9|ADAM7_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 7 OS=Homo sapiens GN=ADAM7 PE=2 SV=3  ali   19  1...................................................................................................................................................................................................................SCTELNFTRKTVPGDNESEEDSKIKGIHDEKYVELFIVADDTVYRRNGHP---------HNKLRNRIWGMVNFVNMIYKTL------NIHVTLVGIEIWTHED----KIELYSNIETTLLRFSFWQEKILKTRKDFDH---VVLLSGKWLYSHVQGISYPGGMCLPYYSTS--------------------------IIKDLLPDTNIIANRMAHQLGHNLGMQHDEFP---CTCPSGKCVMDSDGSIP----ALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFH-----------DFQFCGNKKLDEGEECDCGPAQE----CTNPCC---------DAHTCVLKPGFTCA--EGECC--ESCQIKKAGSICR-PAKDECD....................................................................................................................................................................................................................................................................................................................................... 300
16 -61.500sp|Q9Y3Q7|ADA18_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 18 OS=Homo sapiens GN=ADAM18 PE=2 SV=1  ali   21  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................IAQLLGLNVGLTYDDITQCFC--LRATCIMNHEAVS--ASGRKIFSNCSMHDYRYFVSKFETKCLQKLSNLQPLH----------QNQPVCGNGILESNEECDCGNKNECQ---FKKCC---------DYNTCKLKGSVKCG--SGPCCT-SKCELSIAGTPCRKSIDPECDFTEYCNGTSSNCVPDTYALNGRLCKLGTAYCYNGQCQTTD------NQCAKIFGKGAQGAPFACFKEVNSLHERSENCG-FKNSQPLPCERKDVLCGKLACGTMCGP--EMYCVNKTCRK............................................................................................................................................................................................................... 300
17 -61.400sp|Q9UKQ2|ADA28_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 28 OS=Homo sapiens GN=ADAM28 PE=2 SV=3  ali   22  1.....................................................................................................................................................................................................................................................................................................................................................................................................................SVGVVQDHSDNLLRVAGTMAHEMGHNFGMFHDDYS---CKCPSTICVMDKAL---SFYIPTDFSSCSRLSYDKFFEDKLSNCLFNAPLPTDII-----------STPICGNQLVEMGEDCDCGTSEE----CTNICC---------DAKTCKIKATFQCA--LGECC--EKCQFKKAGMVCR-PAKDECDLPEMCNGKSGNCPDDRFQVNGFPCHHGKGHCLMGTCPTLQ------EQCTELWGPGTEVADKSCYNRNEGGSKYGYCR--RVDDTLIPCKANDTMCGKLFCGTKCGD--NKVCINAECV................................................................................................................................................................................................................ 300
18 -61.300sp|P78325|ADAM8_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 8 OS=Homo sapiens GN=ADAM8 PE=1 SV=1  ali   22  1....................................................................................................................................................................................................................DDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSE----------AAVRHRVLEVVNHVDKLYQKL------NFRVVLVGLEIWNSQD----RFHVSPDPSVTLENLLTWQARQRTRRHLHDN---VQLITGVDFTGTTVGFARVSAMCSHSSGA---------------------------VNQDHSKNPVGVACTMAHEMGHNLGMDHDENVQGCRCQERFEAGRCIMAGSIGSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLV-----------GGPVCGNLFVERGEQCDCGPPED----CRNRCC---------NSTTCQLAEGAQCA--HGTCC--QECKVKPAGELCRPKK............................................................................................................................................................................................................................................................................................................................................ 300
19 -61.000sp|P78325|ADAM8_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 8 OS=Homo sapiens GN=ADAM8 PE=1 SV=1  ali   22  1............................................................................................................................................................................................................................................................................................................................................................................................................................HSKNPVGVACTMAHEMGHNLGMDHDENVRCQERFEAGRCIMAGSI---GSSFPRMFSDCSQAYLESFLERPQSVCLANAPDLSHLV-----------GGPVCGNLFVERGEQCDCGPPED----CRNRCC---------NSTTCQLAEGAQCA--HGTCC--QECKVKPAGELCR-PKKDMCDLEEFCDGRHPECPEDAFQENGTPCSGG--YCYNGACPTLA------QQCQAFWGPGGQAAEESCFSYDILPGCKASRYRADMCGV-LQCKGGQQPLEPVPEGTRCGP--EKVCWKGRCQDLHVYR-SSNCSAQCHNH.............................................................................................................................................................................................. 300
20 -60.900sp|Q9H013|ADA19_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 19 OS=Homo sapiens GN=ADAM19 PE=1 SV=3  ali   22  7.....................................................................................................................................................................................................................TTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRD---------QDATKHKLIEIANYVDKFYRSL------NIRIALVGLEVWTHGN----MCEVSENPYSTLWSFLSWRRKLLAQKYHDN----AQLITGMSFHGTTIGLAPLMAMCSVYQSGG--------------------------VNMDHSENAIGVAATMAHEMGHNFGMTHDSADCCSASAADGGCIMAAAT---GHPFPKVFNGCNRRELDRYLQSGGGMCLSNMPDTRMLY-----------GGRRCGNGYLEDGEECDCGEEEE----CNNPCC---------NASNCTLRPGAECA--HGSCC--HQCKLLAPGTLCR............................................................................................................................................................................................................................................................................................................................................... 300
21 -60.900sp|Q13444|ADA15_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 15 OS=Homo sapiens GN=ADAM15 PE=1 SV=4  ali   25  1..............................................................................................................................................................................................................................................................................................................................................................................................................SICSPDFSGGVNMDHSTSILGVASSIAHELGHSLGLDHDLPGPCPGPAPAKTCIMEAST---DFLPGLNFSNCSRRALEKALLDGMGSCLFERLPS------------LPPMAAFCGNMFVEPGEQCDCGFLDD----CVDPCC---------DSLTCQLRPGAQCA-SDGPCC--QNCQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYA------QQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCGSIRDLLWETIDVNGTCSWVHLD........................................................................................................................................................................................................... 298
22 -60.800sp|Q13443|ADAM9_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens GN=ADAM9 PE=1 SV=1  ali   20  2........................................................................................................................................................................................................................................................................................................................................................................................................................INVFGQITVETFASIVAHELGHNLGMNHDDGRDCSC--GAKSCIMNSGASG-----SRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAY-----------SAPSCGNKLVDAGEECDCGTPKE---CELDPCC---------EGSTCKLKSFAECA--YGDCC--KDCRFLPGGTLCR-GKTSECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYD------AQCQVIFGSKAKAAPKDCFIEVNSKGDRFGNCG-FSGNEYKKCATGNALCGKLQCGTKCGAGK.......................................................................................................................................................................................................................... 299
23 -60.600sp|Q9UKQ2|ADA28_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 28 OS=Homo sapiens GN=ADAM28 PE=2 SV=3  ali   22  4.................................................................................................................................................................................................................DGVLWAHDLQQNIALPATKLVKLKDRKVQEHEKYIEYYLVLDNGEFKRYNEN---------QDEIRKRVFEMANYVNMLYKKL------NTHVALVGMEIWTDKD----KIKITPNASFTLENFSKWRGSVLSRRKRHDI---AQLITATELAGTTVGLAFMSTMCSPYSVGVVQ---------------------------DHSDNLLRVAGTMAHEMGHNFGMFHDDYSCKC---PSTICVMDKALSF---YIPTDFSSCSRLSYDKFFEDKLSNCLFNAPLPTDII-----------STPICGNQLVEMGEDCDCGTSEE----CTNICC---------DAKTCKIKATFQCA--LGECC--EKCQFKKAGMVCRPA............................................................................................................................................................................................................................................................................................................................................. 300
24 -60.300sp|Q9UKF2|ADA30_HUMAN(removed signalp:1-27) Disintegrin and metalloproteinase domain-containing protein 30 OS=Homo sapiens GN=ADAM30 PE=2 SV=2  ali   18  4...........................................................................................................................................................................................................................WQMAPYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNN---------LSQVIHDAILLTGIMDTYFQDV------RMRIHLKALEVWTDFNKIRV---GYPELAEVLGRFVIYKKSVLNARLSSDW---AHLYLQRKY--NDALAWSFGKVCSLEYAGS--------------------------VSTLLDTNILAPATWSAHELGHAVGMSHDEQ----------YCQCRGRLNCIMGSGRTGFSNCSYISFFKHISSGATCLNNIPGL--------------GYVLKRCGNKIVEDNEECDCGSTEE----CQKDRC---------CQSNCKLQPGANCS--IGLCC--HDCRFRPSGYVCR-QEGNECDLAEYCDGNSSSC........................................................................................................................................................................................................................................................................................................................... 300
25 -60.200sp|Q9BZ11|ADA33_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 33 OS=Homo sapiens GN=ADAM33 PE=1 SV=2  ali   25  4.....................................................................................................................................................................................................................RDPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRN---------LNHTKQRLLEVANYVDQLLRTL------DIQVALTGLEVWTERD----RSRVTQDANATLWAFLQWRRGLWAQRPHDS----AQLLTGRAFQGATVGLAPVEGMCRAESSGG--------------------------VSTDHSELPIGAAATMAHEIGHSLGLSHDPDGCCVEAAAESGGCVMAAATG--HPFPRVFSACSRRQLRAFFRKGGGACLSNAPDPGLPV-----------PPALCGNGFVEAGEECDCGPGQE----CRDLCC---------FAHNCSLRPGAQCA--HGDCC--VRCLLKPAGALCRQA............................................................................................................................................................................................................................................................................................................................................. 300
26 -60.100sp|O43506|ADA20_HUMAN(removed signalp:1-31) Disintegrin and metalloproteinase domain-containing protein 20 OS=Homo sapiens GN=ADAM20 PE=2 SV=2  ali   23  1........................................................................................................................................................................................................................HQMELQLSYNFTLKQSSFVGWWTHQRFVELVVVVDNIRYLFSQSN---------ATTVQHEVFNVVNIVDSFYHPL------EVDVILTGIDIWTASN----PLPTSGDLDNVLEDFSIWKNYNLNNRLQHD----VAHLFIKDTQGMKLGVAYVKGICQNPFNTG--------------------------VDVFEDNRLVVFAITLGHELGHNLGMQHDTQW---CVCELQWCIMHAYRKV-----TTKFSNCSYAQYWDSTISSGLCIQPPPYPG------------NIFRLKYCGNLVVEEGEECDCGTIRQ----CAKDPC---------CLLNCTLHPGAACA--FGICC--KDCKFLPSGTLCR-QQVGECDLPEWCNGT............................................................................................................................................................................................................................................................................................................................... 300
27 -59.800sp|O43184|ADA12_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 12 OS=Homo sapiens GN=ADAM12 PE=1 SV=3  ali   21  4.................................................................................................................................................................................................................HHNTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKD---------LEKVKQRLIEIANHVDKFYRPL------NIRIVLVGVEVWNDMD----KCSVSQDPFTSLHEFLDWRKMKLLPRKSHDN---AQLVSGVYFQGTTIGMAPIMSMCTADQSGG--------------------------IVMDHSDNPLGAAVTLAHELGHNFGMNHDTLDRGCSCQMAVEKGGCIMNASTGYPFPMVFSSCSRKDLETSLEKGMGVCLFNLPEVRESF-----------GGQKCGNRFVEEGEECDCGEPEE----CMNRCC---------NATTCTLKPDAVCA--HGLCC--EDCQLKPA.................................................................................................................................................................................................................................................................................................................................................... 300
28 -59.800sp|P78536|ADA17_HUMAN(removed signalp:1-17) Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1  ali   24  1.......................................................................................................................................................................KSEDIKNVSRL---------QSPKVCGYLKVDNEELLPKGLVDREP----------PEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRG--------EESTTTNYLIELIDRVDDIYRNTSWDNAKGYGIQIEQIRILKSPQEVKPGEKHYNMEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPV---GKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQ..................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
29 -59.800sp|Q9UKJ8|ADA21_HUMAN(removed signalp:1-31) Disintegrin and metalloproteinase domain-containing protein 21 OS=Homo sapiens GN=ADAM21 PE=2 SV=2  ali   19  1.......................................................................................................................................................................................................................RQQLEFEEAENSALEPKSAGDWWTHAWFLELVVVVNHDFFIYSQSN---------ISKVQEDVFLVVNIVDSMYKQL------GTYIILIGIEIWNQGNVFPM-----TSIEQVLNDFSQWKQISLSQLQHDA----AHMFIKNSL-ISILGLAYVAGICRPPIDCG--------------------------VDNFQGDTWSLFANTVAHELGHTLGMQHDEEF---CFCGERGCIMNTFRVP-----AEKFTNCSYADFMKTTLNQGSCLHNPPRLG------------EIFMLKRCGNGVVEREEQCDCGSVQQ----CEQDAC---------CLLNCTLRPGAACA--FGLCC--KDCKFMPSGELCR-QEVNECDLPEWCNGTS.............................................................................................................................................................................................................................................................................................................................. 300
30 -59.700sp|O14672|ADA10_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 10 OS=Homo sapiens GN=ADAM10 PE=1 SV=1  ali   38  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EECDCGYSDQ----CKDECCFDANQP---EGRKCKLKPGKQCSPSQGPCCT-AQCAFKSKSEKCR--DDSDCAREGICNGFTALCPASDPKPNFTDCNRHTQVCINGQCAGSICEKYGLEECTCASSDGKELCHVCCMKKMDPSTC-------ASTGSVQWSRHFSGRTITLQPGSPCNDFRGYCDVFMRCRLVDADGPLARLKKAIFSPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQPIQQPQRQRPRESYQMGHMRR.......................................................................................................... 280
31 -59.600sp|Q9H2U9|ADAM7_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 7 OS=Homo sapiens GN=ADAM7 PE=2 SV=3  ali   21  2..........................................................................................................................................................................................................................................................................................................................................................................................................................KDLLPDTNIIANRMAHQLGHNLGMQHDEFP---CTCPSGKCVMDSDGSIP----ALKFSKCSQNQYHQYLKDYKPTCMLNIPFPYNFH-----------DFQFCGNKKLDEGEECDCGPAQE----CTNPCC---------DAHTCVLKPGFTCA--EGECC--ESCQIKKAGSICR-PAKDECDFPEMCTGHSPACPKDQFRVNGFPCKNSEGYCFMGKCPTRE------DQCSELFDDEAIESHDICYKMNTKGNKFGYCK--NKENRFLPCEEKDVRCGKIYCGTKCGEGM-------VCNN............................................................................................................................................................................................................... 300
32 -59.200sp|Q9UKF5|ADA29_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 29 OS=Homo sapiens GN=ADAM29 PE=2 SV=3  ali   18  1....................................................................................................................................................................................................................NEITCRMEFEEIDNSTQKQSSYVGWWIHFRIVEIVVVIDNYLYIRYERN---------DSKLLEDLYVIVNIVDSILDVI------GVKVLLFGLEIWTNKNLIVV-----DDVRKSVHLYCKWKSENITPRMQHD---TSHLFTTLGL-RGLSGIGAFRGMCTPHRSCA--------------------------IVTFMNKTLGTFSIAVAHHLGHNLGMNHDEDT---CRCSQPRCIMHEGNPP-----ITKFSNCSYGDFWEYTVERTKCLLETVHTK------------DIFNVKRCGNGVVEEGEECDCGPLKH----CAKDPC---------CLSNCTLTDGSTCA--FGLCC--KDCKFLPSGKVCR-KEVNECDLPEWC.................................................................................................................................................................................................................................................................................................................................. 300
33 -59.100sp|Q13443|ADAM9_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens GN=ADAM9 PE=1 SV=1  ali   21  1................................................................................................................................................................................................................NKDIEKETAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRN---------QTAVREEMILLANYLDSMYIML------NIRIVLVGLEIWTNGN----LINIVGGAGDVLGNFVQWREKFLITRRRHD---SAQLVLKKGF-GGTAGMAFVGTVCSRSHAGG--------------------------INVFGQITVETFASIVAHELGHNLGMNHDDGR---DCSCGAKSCIMNSGASG----SRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAY-----------SAPSCGNKLVDAGEECDCGTPKE---CELDPCC---------EGSTCKLKSFAECA--YGDCC--KDCRFLPGGTLCRGKTS........................................................................................................................................................................................................................................................................................................................................... 300
34 -58.700sp|Q9UKF2|ADA30_HUMAN(removed signalp:1-27) Disintegrin and metalloproteinase domain-containing protein 30 OS=Homo sapiens GN=ADAM30 PE=2 SV=2  ali   20  1...............................................................................................................................................................................................................................................................................................................................................................................................................................NILAPATWSAHELGHAVGMSHDEQY--CQCRGRLNCIMGSG--------RTGFSNCSYISFFKHISSG-ATCLNNIPG-------------LGYVLKRCGNKIVEDNEECDCGSTEE----CQKDRC---------CQSNCKLQPGANCS--IGLCC--HDCRFRPSGYVCR-QEGNECDLAEYCDGNSSSCPNDVYKQDGTPC-KYEGRCFRKGCRSRY------MQCQSIFGPDAMEAPSECYDAVNLIGDQFGNCEITGIRNFKKCESANSICGRLQCGTSCGE--GRVCFKKNCVNSS............................................................................................................................................................................................................. 300
35 -58.100sp|Q13444|ADA15_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 15 OS=Homo sapiens GN=ADAM15 PE=1 SV=4  ali   24  1........................................................................................................................................................................................DLHLPGHTCALSWRESVHTQKPPE---------------HPLGQRHIRRRRDVVTETKTVELVIVADHSEAQKYR----------DFQHLLNRTLEVALLLDTFFRPL------NVRVALVGLEAWTQRD----LVEISPNPAVTLENFLHWRRAHLLPRLPHDS---AQLVTGTSFSGPTVGMAIQNSICSPDFSGG--------------------------VNMDHSTSILGVASSIAHELGHSLGLDHDLPGNSCPCPGPAPAKTCIMEASTDFLPGLNFSNCSRRALEKALLDGMGSCLFERLPS------------LPPMAAFCGNMFVEPGEQCDCGFLDD----CVDPCC---------DSLTCQLRPGAQCA-SDGPCCQN............................................................................................................................................................................................................................................................................................................................................................ 300
36 -58.000sp|O43506|ADA20_HUMAN(removed signalp:1-31) Disintegrin and metalloproteinase domain-containing protein 20 OS=Homo sapiens GN=ADAM20 PE=2 SV=2  ali   22  1...............................................................................................................................................................................................................................................................................................................................................................................................................................RLVVFAITLGHELGHNLGMQHDTQW---CVCELQWCIMHAYRKV-----TTKFSNCSYAQYWDSTISS-GLCIQPPPYPGNIF-----------RLKYCGNLVVEEGEECDCGTIRQ----CAKDPC---------CLLNCTLHPGAACA--FGICC--KDCKFLPSGTLCR-QQVGECDLPEWCNGTSHQCPDDVYVQDGISCNVN-AFCYEKTCNNHD------IQCKEIFGQDARSASQSCYQEINTQGNRFGHCG-IVGTTYVKCWTPDIMCGRVQCGTVCGP--EKICIRKKCASMVH............................................................................................................................................................................................................ 299
37 -57.400sp|Q9UKF5|ADA29_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 29 OS=Homo sapiens GN=ADAM29 PE=2 SV=3  ali   19  2.............................................................................................................................................................................................................................................................................................................................................................................................................................NKTLGTFSIAVAHHLGHNLGMNHDEDT---CRCSQPRCIMHEGNPP-----ITKFSNCSYGDFWEYTVER-TKCLLETVHTKDIF-----------NVKRCGNGVVEEGEECDCGPLKH----CAKDPC---------CLSNCTLTDGSTCA--FGLCC--KDCKFLPSGKVCR-KEVNECDLPEWCNGTSHKCPDDFYVEDGIPCKER-GYCYEKSCHDRN------EQCRRIFGAGANTASETCYKELNTLGDRVGHCG-IKNATYIKCNISDVQCGRIQCGTECGI--DHICIHRHCVHI.............................................................................................................................................................................................................. 300
38 -57.000sp|Q9UKJ8|ADA21_HUMAN(removed signalp:1-31) Disintegrin and metalloproteinase domain-containing protein 21 OS=Homo sapiens GN=ADAM21 PE=2 SV=2  ali   23  2.................................................................................................................................................................................................................................................................................................................................................................................................................................SLFANTVAHELGHTLGMQHDEEF---CFCGERGCIMNTFRVP-----AEKFTNCSYADFMKTTL-NQGSCLHNPPRLGEIF-----------MLKRCGNGVVEREEQCDCGSVQQ----CEQDAC---------CLLNCTLRPGAACA--FGLCC--KDCKFMPSGELCR-QEVNECDLPEWCNGTSHQCPEDRYVQDGIPC-SDSAYCYQKRCNNHD------QHCREIFGKDAKSASQNCYKEINSQGNRFGHCG-INGTTYLKCHISDVFCGRVQCGTVCGP--GKICIHKKCVSLSVLS.......................................................................................................................................................................................................... 300
39 -56.300sp|Q99965|ADAM2_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 2 OS=Homo sapiens GN=ADAM2 PE=1 SV=2  ali   22  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................SMGITYDDINKCQC--SGAVCIMNPEAIH--FSGVKIFSNCSFEDFAHFISKQKSQCLHNQPRLDPFF----------KQQAVCGNAKLEAGEECDCGTEQD-CALIGETCC---------DIATCRFKAGSNCA--EGPCC--ENCLFMSKERMCR-PSFEECDLPEYCNGSSASCPENHYVQTGHPCGLNQWICIDGVCMSGD------KQCTDTFGKEVEFGPSECYSHLNSKTDVSGNCG-ISDSGYTQCEADNLQCGKLICGTSCGSNK--VCRNQRCVSSSYLG.......................................................................................................................................................................................................... 297
40 -55.200sp|P78536|ADA17_HUMAN(removed signalp:1-17) Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1  ali   22  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ECFQERSNKVCGNSRVDEGEECDPGIMYL----NNDTCCNS----------DCTLKEGVQCSDRNSPCCK--NCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVC-LDLGKCKDGKCIPFCEREQQLESCACN--ETDNSCKVCCRDLSGRCVPYVDAEQKNL---------------FLRKGKPCT--VGFCDMNGKCEKRV-QDVIERFWDFIDQLSI-NTFGKFLADNIVSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPS.................................................................................. 300
41 -54.800sp|O14672|ADA10_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 10 OS=Homo sapiens GN=ADAM10 PE=1 SV=1  ali   27  2.....................QYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSHE----DQFLRLDFHAHGRHFNLRMKRDTSLFSDEFKVETSNKVLD--YDTSHIYTGHIYGEEGSFSHGSVIDGRFEGFIQTRGGTFYVEPAERYI---KDRTLPFHSVIYHEDDINYPHKYGPQG-----------GCADHSVFERMRKYQMTGVEEVTQIPQEEHAANGPELLRKKRTTSAEKNTCQLYIQTDHLFFKYYGTR----------EAVIAQISSHVKAIDTIYQTTDFSGIRNISFMVKRIRINTTAD------EKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVF...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
42 -53.000sp|O75077|ADA23_HUMAN Disintegrin and metalloproteinase domain-containing protein 23 OS=Homo sapiens GN=ADAM23 PE=1 SV=1  ali   22  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................DCTE--SWGGCIMEETGVSH----SRKFSKCSILEYRDFLQRGGGACLFNRPT-------------KLFEPTECGNGYVEAGEECDCGFHVE----CYGLCCK-----------KCSLSNGAHCS--DGPCCNNTSCLFQPRGYECR-DAVNECDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRD------NQCQYIWGTKAAGSDKFCYEKLNTEGTEKGNCG-KDGDRWIQCSKHDVFCGFLLCGTPCGP--SMMCLDRKCLQIQALNPLDSKGKVCSGHGV............................................................................................................................................................................................ 300
43 -52.100sp|Q9P0K1|ADA22_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 22 OS=Homo sapiens GN=ADAM22 PE=1 SV=1  ali   16  35....................................................................................................................................................................................................................TPSKFILKPRPKRSKRQLRRYPRNVEEETKYIELMIVNDHLMFKKHRLS---------VVHTNTYAKSVVNMADLIYKDQ-----LKTRIVLVAMETWATDN----KFAISENPLITLREFMKYRRDFIKEKSDA-----VHLFSGSQFESSRSGAAYIGGICSLLKGGGVNEFGKTD----------------------------LMAVTLAQSLAHNIGIISDKRKLASGECDTWSGCIMGDT---GYYLPKKFTQCNIEEYHDFLNSGGGACLFNKPS-------------KLLDPPECGNGFIETGEECDCGTPAE-------------------------------CVLEGAECCK............................................................................................................................................................................................................................................................................................................................................................. 300
44 -51.900sp|O75078|ADA11_HUMAN(removed signalp:1-23) Disintegrin and metalloproteinase domain-containing protein 11 OS=Homo sapiens GN=ADAM11 PE=2 SV=3  ali   18  5...........................................................................................................................................................GAPQGPLPHLIYRTPLLPDPLGCREPG-------------------------CLFAVPAQSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQS---------VVLTSNFAKSVVNLADVIYKEQ-----LNTRIVLVAMETWADGD----KIQVQDDLLETLARLMVYRREGLPEPSDA-----THLFSGRTFQSTSSGAAYVGGICSLSHGGGVNEYG----------------------------NMGAMAVTLAQTLGQNLGMMWNKHRSSACKCPDIWLGCIMEDTG--FYLPRKFSRCSIDEYNQFLQEGGGSCLFNKPL-------------KLLDPPECGNGFVEAGEECDCGSVQE----CSRAGG----------------------------NC.............................................................................................................................................................................................................................................................................................................................................................. 300
45 -49.800sp|P78536|ADA17_HUMAN(removed signalp:1-17) Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1  ali   15  13.....................QRLEKLDSLLSDYDILSLSNIQ---QHSVRKRDLQTST---HVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFV----NDTKDKRMLVYKSEDIKNVSRLQSPKVCGYL-------------------KVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRG--------EESTTTNYLIELIDRVDDIYRNTSWDNFKGYGIQIEQIRILKSPQ----------EVKPGEKHYNMAKSYPNEEKDAWDVKML.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
46 -48.700sp|O75077|ADA23_HUMAN Disintegrin and metalloproteinase domain-containing protein 23 OS=Homo sapiens GN=ADAM23 PE=1 SV=1  ali   13  1.................................................................ASFQIEAFGSKFILDLILNNGLLSSDYVEIHYENGKPSKGGEHCYYHGSIRGVKDSKVALSTCNG-LHGMFEDDTFVYMIEPLEL---VHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQW--------------------------PFLSELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSS---------HAHTNNFAKSVVNLVDSIYKEQ-----LNTRVVLVAVETWTEKD----QIDITTNPVQMLHEFSKYR------QRIKQHADAVHLISRVTFHYKRSSLSYFGGVCSRTRGVGVNEYGL----------------------------PMAVAQVLSQSLAQNLGIQWEPSSKPKC.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 300
47 -46.400sp|Q6NVV9|ADAM5_HUMAN Putative disintegrin and metalloproteinase domain-containing protein 5 OS=Homo sapiens GN=ADAM5P PE=5 SV=2  ali follow..  16.................................................................................................................................................................................................................................................................................................................................................................................................................QRRFHHRMQKQIQNIISILSSASVINSYDENDIRHSKPLLVQMDCNYNGYV------AGIPNSLVTLSVCSGLRGTMQLKNISYGI--------EPMEAVSGFIHKIYEEKYADTNILLEENDTYTWFNSE---YQVRKSS---------EKTDFIKLFPRYIE--MHIVVD-KNLFKPANMICRK-SVGKECDFTEYCNGDLPYCLPDTYVRDGEYCDSGGAFCFQGKCRTFD------KQCDDLIGRGSRGAPVFCYDEINTRGDNFGNCG------TAHCLFQHILCGKLVCGSMCGPDM--YCFEMHCKHVRFLMNLKLASNHCDRHGVCNNFNHCHCEKGYNPPYCQPQGAFGSIDDGHLVPPTERSYMEEGR............................................................................................................................................... 412
48 -45.500sp|Q9H2U9|ADAM7_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 7 OS=Homo sapiens GN=ADAM7 PE=2 SV=3  ali   10  1.........................KFILGVEGQQLVRPKKLPLIQKRDTGHTHDDDILKTYEEELLYEIKLNRKTLVLHLLRSREFLGSNYSETFYSMKGEAFTRDHCFYQGSIVHEYDSAASISTCNG-LRGFFRINDQRYLIEPV--------KYSDEGEHLVFKYNLRVPYGANYSCTELNFTRKTV--------------------------------PGDNESEEDSKIKGIHDEKYVELFIVADDTVYRRNGHP---------HNKLRNRIWGMVNFVNMIYKTL------NIHVTLVGIEIWTHED----KIELYSNIETTLLRFSFWQEKILKTRKDFDH---VVLLSGKWLYSHVQGISYPGGMCLPYYSTSI........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
49 -44.600sp|P78325|ADAM8_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 8 OS=Homo sapiens GN=ADAM8 PE=1 SV=1  ali   16  3...........................WALMEQYEVVLPRRLP----GPRVRRALPSHLGLHPERVSYVLGATGHNFTLHLRKNRDLLGSGYTETYTAANGSEVTEDHCLYQGHVEGYPDSAASLSTCAG-LRGFFQVGSDLHLIEPL-------DEGGEGGRHAVYQAEHLLQTAGTCGVS------------------------------DDSLGSLLGPRTAAVFRPRPGDSLPSRETRYVELYVVVDNAEFQMLGSE----------AAVRHRVLEVVNHVDKLYQKL------NFRVVLVGLEIWNSQD----RFHVSPDPSVTLENLLTWQARQRTRRHLHDN---VQLITGVDFTGTTVGFARVSAMCSHSSGAVNQD......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
50 -44.100sp|Q9UKQ2|ADA28_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 28 OS=Homo sapiens GN=ADAM28 PE=2 SV=3  ali   12  4...........................LPGVKKYEVVYPIRLHPLHKREAKEPE---QQEQFETELKYKMTINGKIAVLYLKKNKNLLAPGYTETYYNSTGKPQIMDDCYYQGHILNEKVSDASISTCRG-LRGYFSQGDQRYFIEP-------SPIHRDGQEHALFKYNPDEKNYDSTCG---------------------------MDGVLWAHDLQQNIALPATKLVKLKDRKVQEHEKYIEYYLVLDNGEFKRYNEN---------QDEIRKRVFEMANYVNMLYKKL------NTHVALVGMEIWTDKD----KIKITPNASFTLENFSKWRGSVLSRRKRHDI---AQLITATELAGTTVGLAFMSTMCSP................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 299
51 -43.900sp|Q9P0K1|ADA22_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 22 OS=Homo sapiens GN=ADAM22 PE=1 SV=1  ali   15  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KCTLTQDSQCS--DGLCC--KKCKFQPMGTVCR-EAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQGICFGGRCKTRD------RQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCG-KDKDTWIQCNKRDVLCGYLLCGTPCGP--QMMCLEHRCLPVASFNLSSKEGTICSGNGVCSNELKCVCNRHWIGSDCNTYFPHNDDAKTGITLSGNGVAGTN................................................................................................................................................. 261
52 -43.700sp|Q13444|ADA15_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 15 OS=Homo sapiens GN=ADAM15 PE=1 SV=4  ali   12  3...............LPNIGGTEEQQAESEKAPREPLEPQVLQ----DDLPISLKKVLQTSLPEPLRIKLELDGDSHILELLQNRELVPGRPTLVWYQPDGTRVVSENCCYQGRVRGYAGSWVSICTCSG-LRGLVVLTPERSYTLEQG-------PGDLQGPPIISRIQDLHLPGHTCALS-----------------------------WRESVHTQKPPEHPLGQRHIRRRRDVVTETKTVELVIVADHSEAQK----------YRDFQHLLNRTLEVALLLDTFFRPL------NVRVALVGLEAWTQRD----LVEISPNPAVTLENFLHWRRAHLLPRLPHDS---AQLVTGTSFSGPTVGMAIQN...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
53 -43.500sp|O95450|ATS2_HUMAN(removed signalp:1-29) A disintegrin and metalloproteinase with thrombospondin motifs 2 OS=Homo sapiens GN=ADAMTS2 PE=2 SV=2  ali   15  1.....................................................................................................................................GLIRMEEEE-FFIEPLEKGLAAQEAEQGRVHVVYRRPPTSPPLGGPQALDTGASLD---------------------SLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGVDDSVVQFHGKEH-----------VQKYLLTLMNIVNEIYHDESLGA--HINVVLVRIILLSYGK--SMSLIEIGNPSQSLENVCRWAYLQQKPDTGHEYHDHAIFLTRQDFPSGMQGYAPVTGMCHPVRSCTLNH----------------EDGFSS-------------AFVVAHETGHVLGMEHDGQGNRCGDEVRLGSIMAPLV--QAAFHRFHWSRCSQQELSRYLHS--YDCLLDDPFAHDW......................................................................................................................................................................................................................................................................................................................................................................................................................................... 296
54 -43.000sp|Q9BZ11|ADA33_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 33 OS=Homo sapiens GN=ADAM33 PE=1 SV=2  ali   14  4............................QGHIPGQPVTPHWVL---DGQPWRTVSLEEPVSKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLDHCHYQGRVRGFPDSWVVLCTCSG-MSGLITLSRNASYYLRP----WPPRGSKDFSTHEIFRMEQLLTWKGTCGHR--------------------------------DPGNKAGMTSLPGGPQSRGRREARRTRKYLELYIVADHTLFLTRHRN---------LNHTKQRLLEVANYVDQLLRTL------DIQVALTGLEVWTERD----RSRVTQDANATLWAFLQWR-RGLWAQRPHDS---AQLLTGRAFQGATVGLAPVEGMCRAESSGGV........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
55 -42.800sp|Q9H013|ADA19_HUMAN(removed signalp:1-25) Disintegrin and metalloproteinase domain-containing protein 19 OS=Homo sapiens GN=ADAM19 PE=1 SV=3  ali   14  12...........................GSPKLQHELIIP----------QWKTSESPVREKHPLKAELRVMAEGRELILDLEKNEQLFAPSYTETHYTSSGNRKLEDHCFYHGTVRETELSSVTLSTCRG-IRGLITVSSNLSYVIEP--------LPDSKGQHLIYRSEHLKPPPGNCGFE---------------------------HSKPTTRDWALQFTQQTKKRPRRMKREDLNSMKYVELYLVADYLEFQKNRRD---------QDATKHKLIEIANYVDKFYRSL------NIRIALVGLEVWTHGN----MCEVSENPYSTLWSFLSWR-RKLLAQKYHDN---AQLITGMSFHGTTIGLAPLMAMCSVYQS.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 300
56 -42.800sp|Q8WXS8|ATS14_HUMAN(removed signalp:1-22) A disintegrin and metalloproteinase with thrombospondin motifs 14 OS=Homo sapiens GN=ADAMTS14 PE=2 SV=2  ali   14  2...................................................................................................................................LAGLIRTDSTDFFIEPLERG--QQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGD-----------------------LPNLLGLVGDQLGDTERKRRHAKPGSYSIEVLLVVDDSVVRFHGKEH-----------VQNYVLTLMNIVDEIYHDESLGV--HINIALVRLIMVGYRQ--SLSLIERGNPSRSLEQVCRWAHSQQRQDPSHEHHDHVVFLTRQDF--GPSGYAPVTGMCHPLRSCALNH----------------EDGFSS-------------AFVIAHETGHVLGMEHDGQGNGCADETSLGSVMAPLV--QAAFHRFHWSRCSKLELSRYLPS--YDCLLDDPFDPAWPQPPE.................................................................................................................................................................................................................................................................................................................................................................................................................................... 298
57 -42.500sp|Q13443|ADAM9_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens GN=ADAM9 PE=1 SV=1  ali   15  4......................PGFQQTSHLSSYEIITPWRLTRERR---------EAPRPYSKQVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDNHCHYRGYVEGVHNSSIALSDCFG-LRGLLHLENASYGIEPL--------QNSSHFEHIIYRMDDVYKEPLKCGVSNKDIEKE--------------------------TAKDEEEEPPSMTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRN---------QTAVREEMILLANYLDSMYIML------NIRIVLVGLEIWTNGN----LINIVGGAGDVLGNFVQWREKFLITRRRHDS---AQLVLKKGF-GGTAGMAFVGTVCSRSHAG............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 300
58 -42.400sp|O15072|ATS3_HUMAN(removed signalp:1-19) A disintegrin and metalloproteinase with thrombospondin motifs 3 OS=Homo sapiens GN=ADAMTS3 PE=2 SV=4  ali   14  1.....................................................................................................................................GMIKSDNEEYFIEPLERG--KQMEEEKGRIHVVYKRSAVEQAPIDMSKDFHYRESD--------------------LEGLDDLGTVYGNIHQQLNETMRRRRHAGENDYNIEVLLGVDDSVVRFHGKEH-----------VQNYLLTLMNIVNEIYHDESLGV--HINVVLVRMIMLGYAK--SISLIERGNPSRSLENVCRWASQQQRSDLNHEHHDHAIFLTRQDFPAGMQGYAPVTGMCHPVRSCTLNH----------------EDGFSS-------------AFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLV--QAAFHRYHWSRCSGQELKRYIHS--YDCLLDDPFDHDW......................................................................................................................................................................................................................................................................................................................................................................................................................................... 296
59 -42.400sp|Q9UKF5|ADA29_HUMAN(removed signalp:1-18) Disintegrin and metalloproteinase domain-containing protein 29 OS=Homo sapiens GN=ADAM29 PE=2 SV=3  ali   10  3.......................QDEHPQYHSPPDVVIPVRI-----------TGTTRGMTPPGWLSYILPFGGQKHIIHIKVKKLLFSKHLPVFTYTDQGAILEDNNCYYHGYVEGDPESLVSLSTCFGGFQGILQINDFAYEIKPL--------AFSTTFEHLVYKMDSEEKQFSTMRSG---------------------------FMQNEITCRMEFEEIDNSTQKQSSYVGWWIHFRIVEIVVVIDNYLYIRYERN---------DSKLLEDLYVIVNIVDSILDVI------GVKVLLFGLEIWTNKNL------VVDDVRKSVHLYCKWKSENITPRMQHDT---SHLFTTLGL-RGLSGIGAFRGMCTPHRSCAIVTF........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 300
60 -42.200sp|O43506|ADA20_HUMAN(removed signalp:1-31) Disintegrin and metalloproteinase domain-containing protein 20 OS=Homo sapiens GN=ADAM20 PE=2 SV=2  ali   13  3...........................SQYFTSPEVVIPLKVI------------RGRGAKAPGWLSYSLRFGGQRYIVHMRVNKLLFAAHLPVFTYTEQHAPFIQDDCYYHGYVEGVPESLVALSTCSGGFLGMLQINDLVYEIKPI--------SVSATFEHLVYKIDSDDTQFPPMRCG---------------------------LTEEKIAHQMELQLSYNFTLKQSSFVGWWTHQRFVELVVVVDNIRYLFSQSN---------ATTVQHEVFNVVNIVDSFYHPL------EVDVILTGIDIWTASN----PLPTSGDLDNVLEDFSIWKNYNLNNRLQHDV---AHLFIKDTQ-GMKLGVAYVKGICQNPFNTGVDVFED...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 299
61 -42.000sp|Q9UNA0|ATS5_HUMAN(removed signalp:1-18) A disintegrin and metalloproteinase with thrombospondin motifs 5 OS=Homo sapiens GN=ADAMTS5 PE=1 SV=2  ali   12  2..........................................................................................................RGPWAEE-------EKGRVYGDGS-ARILHVYTREGFSFEALPP---RASCETPASTPEAHEHAPAH---------------------------SNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMARLYGRG------------LQHYLLTLASIANRLYSHASIEN--HIRLAVVKVVVLGDKD---KSLEVSKNAATTLKNFCKWQHQHNQLGDDHEHYDAAILFTREDLSCDTLGMADVGTICSPERSCAVIE----------------DDGLHA-------------AFTVAHEIGHLLGLSHDDSKFCEEGSTEDKRLMSSIL--TSIDASKPWSKCTSATITEFLDDG....................................................................................................................................................................................................................................................................................................................................................................................................................................................... 299
62 -41.800sp|O43184|ADA12_HUMAN(removed signalp:1-28) Disintegrin and metalloproteinase domain-containing protein 12 OS=Homo sapiens GN=ADAM12 PE=1 SV=3  ali   12  21..............................................SGDLWIPVKSFDSKNHPEVLNIRLQRESKELIINLERNEGLIASSFTETHYLQDGTTVILGHCYYHGHVRGYSDSAVSLSTCSG-LRGLIVFENESYVLEPM--------KSATNRYKLFPAKKLKSVRGSCGSHH-----------------------------NTPNLAAKNVFPPPSQTWARRHKRETLKATKYVELVIVADNREFQRQGKD---------LEKVKQRLIEIANHVDKFYRPL------NIRIVLVGVEVWNDMD----KCSVSQDPFTSLHEFLDWRKMKLLPRKSHDN---AQLVSGVYFQGTTIGMAPIMSMCTAD................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 300
63 -41.500sp|Q99965|ADAM2_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 2 OS=Homo sapiens GN=ADAM2 PE=1 SV=2  ali   12  3...........................NFDSLPVQITVPEKIR------------SIIKEGIESQASYKIVIEGKPYTVNLMQK-NFLPHNFRVYSYSGTGIQDFQNFCHYQGYIEGYPKSVVMVSTCTG-LRGVLQFENVSYGIEPL--------ESSVGFEHVIYQVKHKKADVSLYNEK--------------------------------------DIESRDLSFKLQSVEPQQDFAKYIEMHVIVEKQLYNHMGSD---------TTVVAQKVFQLIGLTNAIFVSF------NITIILSSLELWIDEN----KIATTGEANELLHTFLRWKTSYLVLR-PHD---VAFLLVYREK-SNYVGATFQGKMCDANYAGGVVLHP-------------------------RTISLESLAVILAQLLS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 300
64 -41.500sp|O75078|ADA11_HUMAN(removed signalp:1-23) Disintegrin and metalloproteinase domain-containing protein 11 OS=Homo sapiens GN=ADAM11 PE=2 SV=3  ali   16  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................CKKCTLTHDAMCS--DGLCC--RRCKYEPRGVSCR-EAVNECDIAETCTGDSSQCPPNLHKLDGYYCDHEQGRCYGGRCKTRD------RQCQVLWGHAAADRFCYEKL--NVEGTERGSCG-RKGSGWVQCSKQDVLCGFLLCGTACGP--NMLCLDHRCLPASAFNPGSGERRICSHHGVCSNEGKCICQPDWTGKDCSI---HNPLPTSPPTGETERYKGPSG................................................................................................................................................ 259
65 -41.400sp|P78325|ADAM8_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 8 OS=Homo sapiens GN=ADAM8 PE=1 SV=1  ali   14  1...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DMCDLEEFCDGRHPECPEDAFQENGTPC--SGGYCYNGACPTLA------QQCQAFWGPGGQAAEESCFSYDILPGCKASRYR-ADMCGVLQCKGGQQPLGRAICGTRCGPEK--VCWKGRCQDLHVYR-SSNCSAQCHNHGVCNHKQECHCHAGWAPPHCAKLLTEVHAASGSLPVLVVVVLVLLAVVLVTLAGIIVYRKARSRILSRNVAPKTTMGRSNPLFHQAASRVPAKGG-------APAPSRGPQELVPTTHPGQPARHPASSVALKRPPPAPPVTVSSPPFPVPVYTRQA................................. 300
66 -41.000sp|Q9UKJ8|ADA21_HUMAN(removed signalp:1-31) Disintegrin and metalloproteinase domain-containing protein 21 OS=Homo sapiens GN=ADAM21 PE=2 SV=2  ali   11  3...........................SQHFTSPEVVIPLKVI------------RGRSAKAPGWLSYSLRFGGQKHVVHMRVKKLLVSRHLPVFTYTDDRALLEDDDCYYHGYVEAAPESLVVFSACFGGFRGVLKISGLTYEIEPI--------RHSATFEHLVYKINSNETQFPAMRCG--------------------------LTEKEVARQQLEFEEAENSALEPKSAGDWWTHAWFLELVVVVNHDFFIYSQSN---------ISKVQEDVFLVVNIVDSMYKQL------GTYIILIGIEIWNQGNVF-----PMTSIEQVLNDFSQWK-QISLSQLQHDA---AHMFIKNSL-ISILGLAYVAGICRPPIDCGVDNFQGDT.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
67 -41.000sp|Q9UKP4|ATS7_HUMAN(removed signalp:1-27) A disintegrin and metalloproteinase with thrombospondin motifs 7 OS=Homo sapiens GN=ADAMTS7 PE=1 SV=2  ali   16  4...................................................................................................................................................................HVVYKRQAPERLAQ------RGDSSAPSTCGVQVYPELESRR-----------ERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVADAKMVEYHGQPQ-----------VESYVLTIMNMVAGLFHDPSIGN--PIHITIVRLVLLEDEE---EDLKITHHADNTLKSFCKWQKSINMKGDAHLHHDTAILLTRKDLPCETLGLSHVAGMCQPHRSCSINE----------------DTGLPL-------------AFTVAHELGHSFGIQHDGSGNDCEPVGKRPFIMSPQLLY--DAAPLTWSRCSRQYITRFLDRGWGLCLDDPPAKDII-----------DFPSVPPGVLYDVSHQCR............................................................................................................................................................................................................................................................................................................................................................................................................ 298
68 -40.900sp|Q8TE58|ATS15_HUMAN(removed signalp:1-17) A disintegrin and metalloproteinase with thrombospondin motifs 15 OS=Homo sapiens GN=ADAMTS15 PE=2 SV=1  ali   15  2...........................................................................................................................................................................................DPTSRCGVASGWNPAILR-----ALDPYKPRRAGFGESRSRRRSGRAKRFVSIPRYVETLVVADESMVKFHGAD------------LEHYLLTLLATAARLYRHPSILN--PINIVVVKVLLLRDRD---SGPKVTGNAALTLRNFCAWQKKLNKVSDKHEYWDTAILFTRQDLTCDTLGMADVGTMCDPKRSCSVIE----------------DDGLPS-------------AFTTAHELGHVFNMPHDNVKVCEEGKLRANHMMSPTLIQ--IDRANPWSACSAAIITDFLDSGHGDCLLDQPSKPISL-----------PEDLPGASY-TLSQQCELAFGVGSKPCPYMQYCT........................................................................................................................................................................................................................................................................................................................................................................................... 299
69 -40.700sp|Q13444|ADA15_HUMAN(removed signalp:1-20) Disintegrin and metalloproteinase domain-containing protein 15 OS=Homo sapiens GN=ADAM15 PE=1 SV=4  ali   15  1................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................CQLRPSGWQCR-PTRGDCDLPEFCPGDSSQCPPDVSLGDGEPCAGGQAVCMHGRCASYA------QQCQSLWGPGAQPAAPLCLQTANTRGNAFGSCGRNPSGSYVSCTPRDAICGQLQCGTACGP--GLVCIDHRCQRVDLLG-AQECRSKCHGHGVCDSNRHCYCEEGWAPPDCTTQLATSSLTTGLLLSLLVLLVLVMLGASYWYRARLHQRLCQLKGPTCQYRAAQSGPSERPGPPQRALLARGTKQASALSFPAPP..................................................................................... 300
70 -40.400sp|P59510|ATS20_HUMAN(removed signalp:1-21) A disintegrin and metalloproteinase with thrombospondin motifs 20 OS=Homo sapiens GN=ADAMTS20 PE=2 SV=2  ali   15  3..........................................................................................................................................................EYEDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKET--SLPFHTYSNMNEDLNVMKERVLGHTSKNVPLKDERRHSRKKRLISYPRYIEIMVTADAKVVSAHGSN------------LQNYILTLMSIVATIYKDPSIGN--LIHIVVVKLVMIHREE---EGPVINFDGATTLKNFCSWQQTQNDLDDVHSHHDTAVLITREDIKCNMLGLSYLGTICDPLQSCFINE----------------EKGLIS-------------AFTIAHELGHTLGVQHDDNPRCKEMKVTKYHVMAPALSF--HMSPWSWSNCSRKYVTEFLDTGYGECLLDKPDE............................................................................................................................................................................................................................................................................................................................................................................................................................................ 298
71 -40.400sp|Q8TE56|ATS17_HUMAN(removed signalp:1-27) A disintegrin and metalloproteinase with thrombospondin motifs 17 OS=Homo sapiens GN=ADAMTS17 PE=2 SV=2  ali   14  1...................................................................................................................................................................HLIRRKWSLTPSPSAEAQR------------------------PEQLCKVLTEKKKPTWGRPSRDWRERRNAIRLTSEHTVETLVVADADMVQYHGAEA-----------AQRFILTVMNMVYNMFQHQSLGI--KINIQVTKLVLLRQRP---AKLSIGHHGERSLESFCHWQNEEYGGARYLGNVDAAVFVTRTDFPCDTVGIAYLGGVCSAKRKCVLAE----------------DNGLNL-------------AFTIAHELGHNLGMNHDDDHSSC---AGRSHIMSGEWVKGRNPSDLSWSSCSRDDLENFLKSKVSTCLLVTDPRSQHT--------VRLPHKLPGMHY-SANEQCQ............................................................................................................................................................................................................................................................................................................................................................................................................ 300
72 -40.300sp|Q9UKF2|ADA30_HUMAN(removed signalp:1-27) Disintegrin and metalloproteinase domain-containing protein 30 OS=Homo sapiens GN=ADAM30 PE=2 SV=2  ali   10  8...........................EGEFDSYEVTIPEKLS------------RGEVQGVVSPVSYLLQLKGKKHVLHLWPKRLLLPRHLRVFSFTEHGELLEDKDCNYMGSVKESLDSKATISTCMGGLRGVFNIDAKH-YQIEPL-------KASPSFEHVVYLLKKEQFGNQVCGLSDDEIEWQMA--------------------------------PYENKARLRDFPGSYKHPKYLELILLFDQSRYRFVNNN---------LSQVIHDAILLTGIMDTYFQDV------RMRIHLKALEVWTDFNKIRV---GYPELAEVLGRFVIYKKSVLNARLSSDW---AHLYLQRKY-NDALAWS-FGKVCSLEYAGSVSTLLDT..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 300
73 -40.100sp|O75078|ADA11_HUMAN(removed signalp:1-23) Disintegrin and metalloproteinase domain-containing protein 11 OS=Homo sapiens GN=ADAM11 PE=2 SV=3  ali   13  11......................GGLPQLGGPGAPEVTEPSRLVKQQLDTRVRQEPPGGPPVHLAQVSFVIPAFNSNFTLDLELNHHLLSSQYVERHFSREGTTQHSDHCYYQGKLRGNPHSFAALSTCQG-LHGVFSDGNLT-YIVEPQEVAGPWGAPQGPLPHLIYRTPLLPDPLGCREPG-------------------------CLFAVPAQSAPPNRPRLRRKRQVRRGHPTVHSETKYVELIVINDHQLFEQMRQS---------VVLTSNFAKSVVNLADVIYKEQ-----LNTRIVLVAMETWADGD----KIQVQDDLLETLARLMVYRREGLPEP.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 300
74 -39.900sp|Q9H324|ATS10_HUMAN(removed signalp:1-25) A disintegrin and metalloproteinase with thrombospondin motifs 10 OS=Homo sapiens GN=ADAMTS10 PE=1 SV=2  ali   18  2...................................................................................................................................................................HVVYKRSSLRHPH------------LDTACGVRDEKPWK----GRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVADKMMVAYHGRRD-----------VEQYVLAIMNIVAKLFQDSSLGS--TVNILVTRLILLTEDQ---PTLEITHHAGKSLDSFCKWQKSIVNHSGHGNAHDTAVLITRYDIPCGTLGLAPVGGMCERERSCSVNE----------------DIGLAT-------------AFTIAHEIGHTFGMNHDGVGNCGARGQDPAKLMAAHITM--KTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTV------------------PGQAYDA........................................................................................................................................................................................................................................................................................................................................................................................................... 300
75 -39.700sp|Q8TC27|ADA32_HUMAN(removed signalp:1-16) Disintegrin and metalloproteinase domain-containing protein 32 OS=Homo sapiens GN=ADAM32 PE=1 SV=2  ali   11  4...........................GFQNSLLQIVIPEKIQTNTN---------DSSEIEYEQISYIIPIDEKLYTVHLKQR-YFLADNFMIYLYNQGSSSDIQTQCYYQGNIEGYPDSMVTLSTCSG-LRGILQFENVSYGIEPL--------ESAVEFQHVLYKLKNEDNDIAIFIDR---------------------------------SLKEQPMDDNIFISEKSEPAVPDLFPLYLEMHIVVDKTLYDYWGSD---------SMIVTNKVIEIVGLANSMFTQF------KVTIVLSSLELWSDEN----KISTVGEADELLQKFLEWK-QSYLNLRPHDI---AYLLIYMDY-PRYLGAVFPGTMCITRYSAGVALYPK...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 292

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24