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Query: [J] COG0013 Alanyl-tRNA synthetase, from VFDB

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKTMTSAEVRQMFLDFFKSKGHTVEPSQSLVPVNDPTLLWINSGVATLKKYFDGSVVPENPRLTNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRKEAIAFAWELLTSSEWFEFPAEKLYITYYPADKDTYNRWVEVGVDPTHLVPIEDNFWEIGAGPSGPDTEIFFDRGEVYDPEHVGLKLLAEDIENDRYIEIWNIVLSQFNADPSIPRSEYPELPQKNIDTGMGLERMVCIIQGGKTNFDTDLFLPIIREIEKLSGKTYSPDSENMSFKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRAVMHGKKLGIQGKFLASLVPTVGKIMQSYYPEVLEKEDFIMQIIDREEETFNRTIDAGQKLIDELLLNLKSEGKDRLEGADIFRLYDTYGFPVELTEELAEDEGFKIDHEGFKVAMKAQQERARAAVVKGGSMGAQNETLSSIEVESEFLYEDKTTQGKLLVSIQDDEIVDEVSGKAQLVFDVTPFYAEMGGQVADHGVIKDAEGQVVANVLDVQHAPHGQNLHSVETLSPLKVGESYTLEIDKERRAAVVKNHTATHLLHAALHNIVGNHALQAGSLNEVEFLRFDFTHFAQVTKEELAEIERQVNEVIWQSLKVETVETDIATAKEMGAMALFGEKYGKNVRVVKIGDYSIELCGGTHTQTTSEIGLFKIVKEEGIGSGVRRIIAVTGQKAYEAFKDAENTLNEVATMVKAPQTSQVLAKVTSLQDELKTAQKENDALAGKLAASQSDEIFKNVQTAGSLNFIASEVTVPDANGLRNLADIWKQKELSDVLVLVAKIGEKVSLLVASKSSDVKAGNLVKELAPFVDGRGGGKPDMAMAGGSKAAGIPELLAAVAEKLALast
1 -4.140PB011130 gi|88806557|ref|ZP_01122074.1| hypothetical protein RB2501_00756 [Robiginitalea biformata HTCC2501]gi|88783389|gb|EAR14561.1| hypothetical protein RB2501_00756 [Robiginitalea biformata HTCC2501]  ali follow..  10  1.................................................................................................................................................................................................................................................................................................................................MNKTVNINLANMLFHIDENAYQKLLRYLEAVKRSFAGTAGS-DEIIADIEARIAELFYEKMENERQVITQKEVDAVIAIMGQPEDYQVDEDIFEDVPPGTGSAKSRTTRSAKK...................................................................................................................................................................................................................................................................................................................................................................................................................................................... 112
2 -2.880HGC00164 gi|163636082|dbj|BABG01000191.1|4.0 TMP00833;  ali follow..  10  1..............................................................................................................................................................................................................................MNDLIVDVKLWGESVGSLYWEKESNYERKFIRSGLDISPIIMPISQYRNTPYRFLENRTDCFKGLPGLFAD-SLPDTFGNQIINEWFASKALEFEPSSPINGMNESSVLH--IEELTELAKSVFTDRMAFQVQLRQEGRNILDILKVG...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 172
3 -2.670HGC00803 gi|163280588|dbj|BABD01030100.1|2.0 TMP01051;  ali follow..  11  3..............................................................................................................................................................................................................................................................................EKGAIPMKAFDPNYKLLDEMYQDDYYPAF------VKDELQKVIDLLESGETDTEVIQETLDEAVCGINDLQEEFDENDSEIETVARDC-------------------------------GVTVAYILEWFGIPIDIEEAIRERD......................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 115
4 -2.620PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  20  183..TFTFKEIKFKKINFFSSIFLSFISIFAL------TITFA------YNSTFL-----------NLAQIVRINTIRPNPNPNPNEIFNFDLNNLPINGLLTVEAI---WFLLTDTATVIIINNTAYVNINKNSVKHNNF-------AVNYLKSEENNWYL-TGRDFPLLGLFVEKFFKDD------------------VEVFSLYFVVNNS-------------TKNIFSSVGISSLSTNNPKLIFTFTFD............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 377
5 -2.590PB015954 Q6WBB3_BIFBR/1-225 PB015954; Pfam-B_15954;  ali follow..  1..........................................................................METSSIELWHGSSHVIKHDYGRGFYCIELAKEWACAGLDDGFAYTLTTDGLTFLDLSQPPYTILNWLAL---------------------------LVENRRFQPTTAVAAQGIEYLRQVFLPDISQADVIV------GYRADDSYFSFARTFVNNAISLDQLADAMRLGELGKQIVLISSRAFAALQFQDCEIARASTYHVLRNERDVTAREAY---RRKSAEADIDGLFMRDIIREKVTND........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 222
6 -2.550PB048276 _Gut.Meta.Jp.0112258_ gi|163310311|dbj|BABD01000385.1||2 (- 258:885~0 complete)  ali follow..  12  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ENTQIKLSETVMVIDVAYLNFVINDLRKYFEPLLGRSLQTDLALFTMYLAMDAGLKGSDVLLVYDKQSGKLEHCLPSDLKNELDGVAFKASLGEFSFMAAPSEGFVSRGDLYLDLL----------QIVLNAAEVKKLIVVPFNEEYGKEVENVLRECALENAGHKEEAKDIVYFRMEE............................................................................................................. 174
7 -2.550PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;  ali follow..  12...................................................................................................................................................................................................SRWDSLW---FLLFYCNFLKGVFLLRIAVVDGQGGGIGKHITARLRQELPP--EVEILALGTNAAATVAMIKAGANEGATGERAIIYNAPRVEAITGSAIILADAMLGELTPAMA-AAIAASPARKFLLPINRSGVEVIGVTPEPLPHLIEALVNRVKFFYQEGGDK.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 174
8 -2.230PB053359 gi|153891307|ref|ZP_02012332.1| conserved hypothetical protein [Opitutaceae bacterium TAV2]gi|151582630|gb|EDN46158.1| conserved hypothetical protein [Opitutaceae bacterium TAV2]  ali follow..  1...............LIAPDGSFPPVGRSIAYRCGAFQLLAQMALRRELPEGVAPAQVGAPGTFDNDTGNDGAGWLRIGLAGHQPGLGE--------VYISTGSLYLCTTAFL---PLGLPASDDFWSQPDAPWTSARVW............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 126
9 -2.210PB022697 Q5LAY4_BACFN/1-165 PB022697; Pfam-B_22697;  ali follow..  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IEVTDASLQKAAGEGMDEFIQVFTDKYKEVIGGELTAETMPLLTGEQHSLLAYQIFRDEVM------------GGFCQLIQNGYGGYIFDNP--FAKVMRLWGA---EDFSKLVYKAKKIYDAHRHDLEKERTEDEFMAMYEQYEAFDDLEEEYLDIEEEVTALVASYVDDHLEL...................................................................................................... 160
10 -2.200PB000790 _Gut.Meta.Jp.0111831_ gi|163310496|dbj|BABD01000203.1||3 (- 2591:4589~0 complete)  ali follow..  13  229...FAPWES--YFL---AEYGWISNITPKEAYELGIRSSFEYFGVSEYADQYINSTT--RNRLGTSVAFDDTVEPTSEVMTYRDGYTNTDQIQEVVYNYPTASKTLYG----AMNDHLTKIITQKYIAQMPYQ-EIWNDHRRLGLPFFEIPANESD--QWDFYP--PTTLD------NADPENYQKAVELLGGSDVIITPLW.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 436

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Li Z, and Godzik A. Modeling and Analyzing Three-Dimensional Structures of Human Disease Proteins Pacific Symposium on Biocomputing 11:439-450(2006) [PDF]