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Query: [E] COG2902 NAD-specific glutamate dehydrogenase, from VFDB

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGYRNNPKREKQIEKARQQAIAENVQFLDPGILYGRASADDIEYYSAEMLAASAAHSFEALSHWTGDAPHISITTVEGVSPRDIPVTVLTIIGRNMPFLYDSVMGEVTSSYRGLYLAVHPILVRDDEAQGYRLAEPEDDPAENISLIQLHIAPLTPQAASALEERLRFVLTQVQSAYRDWRPMLTKLDEALDELSKRGSSRRKTERTEAVEFLNWLRNDNFTFLGMRDYTYSGKGKNAKIERGDGVGLGSLSDPDVRVLRLGKNAVTTTPEILAFLDGPDFLIVTKANVKSIVHRRAYMDYIGIKRFDEDGNVIGELRIVGLFTATAYTRSVKQIPLLRAKVADVERHFGFDPNSHSGRILQNTLEAYPRDDLFQIETDLLIRFIEQIMELSDRPRVRVLARIDRFDRFVSAIIFVPREEYNSYVREKIGDYLSRVYDGHISAYYPAFPEGAVARVHFIVGRTEGKTPRIAQDKLEDAVSDIAARWIDHFVALSEPGAPVLDVDQAYQEAFTPEEAIGDMPDILAAANGEPVRIEFYQQEGQSDDTLSLKIFHRDGHLPLSRRVPLLENLGFNVISERTFDIGVVSEGEKRDIVLHDMELSVAAGTTLDLPHYGPKLEEAFLAAFSGKVDNDNFNRLILACGLNVREVSVLRAYARYLRQTGIVYSQEHISETLYKYPDISRNIFALFKAGFDPSIEEKKRVKKLAEIHKAIEAALSGVPNLDEDRTLRRYVNAIDATLRTNYFQKNADGTPRDLLAFKFDPKHLDGLPDPRPFREIFVYGTEVEGVHLRFGKVARGGLRWSDRGQDYRTEVLGLVKAQQVKNAVIVPVGAKGGFFPKNLPAGGSRDEVFNAGREAYKTYIRTLLSITDNIVDDAIVPPADTLRLDGDDPYFVVAADKGTATFSDTANGLAHEAGFWLDDAFASGGSAGYDHKKMGITARGAWETVKRHFREMDTDIQTTPFTVAGVGDMSGDVFGNGMLLSEKIRLIAAFDHRDIFIDPDPDTDKSFAERKRLFELPRSSWQDYDRSTLSAGAMIISRSEKSVTLTPEAVAAIGLDKSVATPFEIMTAILKAPTDLLWFGGIGTYIKAAVETNAEVGDRANDPIRVNATELRAKVIGEGANLGITQKGRIAYALAGGRCNSDAIDNSAGVNSSDVEVNIKIALASAVNSGRLTMPKRNQLLASMTPDVAQLVLRNNYQQSLAISLTERLGLANREELGRLMGALEATGQLNRKVETLPNNAEFSERYASGKPLTRPEIGVLLSYAKLTLFDALVASPLPDEPYLQHLLLDYFPAKMQKNYANDIKAHRLHREIVATALANAVVNRGGPGFVQKLADASGLLAADVVKAAVIVEDGFGLKRLWTEVDALDGKVGGQVQNGLYATITRIFSDASRLYLQTGSAGAAAGDMATEIERLKTAIKTLSPAATKYRRELGVTEIDGVPSGLLEELDTLSLLVYVPEIMRIAESAGTTLARAAESYATVSSTFRVARLLDASQRITPADHYESLALLRSQDQISSSRRRIVISALTEYAKEKDPVQAWYAADRVRVNRIVSELGALSESGDTNLARLTVAAGLLGDIVQARLast
1 -3.400PB038401 Q8RFH0_FUSNN/1-210 PB038401; Pfam-B_38401;  ali follow..  10  1.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MDIGPCSIPTGEFLVGDPLVYLGSKYEKEYFQKIPTGEFRTEICVVKASDGDCDRY---------AAVRLKFNDNEISYFEEAMKGIEDLKDINEGDFFGFNVDAGLACICDKKLHDLYCE------IFQSGFGDGAYPVYLAYDKDGNVCQLIVELIDIELAYSEID................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 206
2 -2.790PB017124 _Gut.Meta.Jp.0039711_ gi|162659581|dbj|BAAX01000024.1||2 (+ 385:1498~0 complete)  ali follow..  11  2......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SAQAKQTVKVLEYCKLPEINNTMSAEERLEQLEDGNLVCLGAAGGYITV-ALDQPIKNGKGS-LGNAFYSANDPKYGDATIGGSVEPGIVYVGV-----SSPETAEWYELAGSEYYTTEMHRFEITYYKPTVETGEIKTPYIWTASWTNPDGSKQTAEGWQPKNVYHKQSYWPAWEENDQITF----RGARLPDNAVNYGGDGSDPDNPQYWVSYRYAADSY-------GYADAAPNSDNVYTTFDLDWAVDSDGNPKHLDHA--------------------IRIQSGVLQQCGWTGETSTEVG.......................................................................................................................................................................................................................................................................................................................................................................................................................................... 294
3 -2.260PB044822 Q89ZL7_BACTN/1-147 PB044822; Pfam-B_44822;  ali follow..  11  1........................................................................................MKLSQQSLSTIESAIQKAAGKYVCGCDQTAVTDIHLQPDTSGQLTIYNDDDEELANVMIEEWATYDGDDFMENVKPNLKSTLCRMKVLVDEDKETVAELLLIDDDTLLVDDELLKGLDKELDEFLKNLLE....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 147
4 -1.990HGC00044 gi|162658718|dbj|BAAX01000887.1|1.0 TMP00920;  ali follow..  10  24...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AYAS------TEWNYDNEVAYGFGYGL--SYTT-----FTQEIQGQPEISVNIDSETGAPQAYATFN---VKVTNTGKVPGK------------TSVQIY-----GQAPYTEGGLE---------KVAIQLLNFEKSSELAPG-----ASEIVSVKVDLQYIASYDMEH-------------------DGTTGTYVLDPGTYYFAAGNGAHD---------------------ALNNILVLQGADESKMVGTGSAAAAVAQEITEDLISRTAFSVSKTGEKISNQIPYADWNYYQPGEVTYLTRADWAGTFPKTYDQMTLTSEKLISDLNGNYYTIATDDDTSDIKWGENSNLMFYQMFGLDFDDPKWDELLDKMTLEEAQYLATYGGPSIPGVESI----TVETYM............................................................................................................................................................................................................................................................................................... 344
5 -1.960PB000119 Q6KIT1_MYCMO/1-381 PB000119; Pfam-B_119;  ali follow..  16  148.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NLIEGFSNFLFCIVVAPNLVKILNKNLPNLWGEKFTFTFKEIKFKKINSSIFLSFISIFALTITFAYNSTF----LNLAQIVRNTIRPNPNPNP--NEIFNF----DLNNLPI----ENGLLTVEAI-------------------FLQSKMELTDTA----------TVIIINNTAYVNI--NKNSVKHNNFANYLKSEENNWY---------TGRDFPLLGL-------FVEKFFKD-DVEVFSPKIPAL-VNNSTKNIFSSSSLSTNNPKLIFTFTFDNGF............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 380
6 -1.280PB155142 _HOMD.0127537_ bfor_c_1_1790 Tannerella forsythia ATCC 43037 [677748 - 680894] ORF  ali follow..  13  12.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................INPEDIESQTILKDAAATALYGSRANGVVLKSGRRGKTHIAFTAESDFATPHALDYMDAGQYAQYTWESLKNKYLYDRKAMPEQAKADTYESLLPEAERYAYRNLAAASGLYHPDDPFDGTFNYKNMTPEQQKMFITNPRIVNWRDAIFKTGAVQKYDLS---LNGGSFGYLKND-GLVQGSVF---ERFSGALSLNLKLHDRVLLKLS......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 228
7 -1.280PB001565 Q6LS01_PHOPR/1-384 PB001565; Pfam-B_1565;  ali follow..  11  16.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VNMVVLTKQF------VLSTLVTNKRCHTTTYASHAIT---LNFEDTIMALFESYDRRIDQ-ASFEEALEYCKERNVNPYDIVKETQPIAFENASWAYVLGAAIALKED----KNAAEAAEYIGQGLQAFCIPGSVADQRQVGLRLLNNDTQCFCFLAGHAAEGAIKIAMNANKVRHHPLRVILNGLGKDAAYMIARINGFNYVQTQFNYETGELDVVS-----RRFSTSQRGDINCYGADDVREGVAIMHREEVD-ISITGNSTNPTRFQHPVAGTYKKERLEANQAYASGGGTG-DNVAAGPASYGMTDTMGRMHSDAQFAGSSSVPAHVEMMGLIG--MGNNPMVGATVAVAVAIEQA............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 384
8 -1.200HGC00965 gi|163282470|dbj|BABD01028218.1|2.0 TMP01310;  ali follow..  11  17....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PMLHYLQNKNSFSG--------NEDGMRYLITPGKRSVPDPDGGEEAKKEEAILTVDLWPEPWTLDKTDPALRRREIFPMTEEGRTAVAQYLNDAYNAEPER-----SAHPSILDCEPWTPPAPEPDAET........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 134
9 -1.200HGC00803 gi|163280588|dbj|BABD01030100.1|2.0 TMP01051;  ali follow..  11  33..............................................................................................................................................................VDKVKDELQKVIDLLESGETDTEVIQETLDEAVCGINDLQEEFDENDSEIETVARDCIGVTVAYILEWFGIPIDIEE...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 109
10 -1.200PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  10  89......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DKPKESIQDYEQEYENQLKDILETIIGVEDVSIVVNVDATSLKIFEKN--ETDKQGGKRTVSEMSSDEEIVKNGDKETPV-VVQTKKPDIRGVLV----VAQGV---VQIKKTIIEAVTRVLDVPSHRVAVAPKKMKE................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 229

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.