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Query: [H] KOG1370 S-adenosylhomocysteine hydrolase, from VFDB

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDKLPYKVAAWGRKALDIAENKMPGLMRIWERYSASKPLNGARIPGCLHRTVETAVLMSLITLGTEVQWSSCNIFSTQDHAAAAIAKAGISASTGIPVLPLPRLACLEGRNRRGVPVTGDLTNLIHSEYSQLLLSFRGISKETTIGVHNLYKMMVNGILKVPAIDVNDSATKSKFDNLYGCGIKQATDVMIAGKVAVVAGYGDKGKSCAQALRGFRASVIITKTDPIKALQAAMEGYEVTTMDEACQEGDVFVTTTGCVDIILGQHFEQTKDDTIVCNTGYFDVEMDVKWLNKNTVEKVNVKLQVDPYRLKNGRGIILLAEGRLVNLACAMGHPSFVRSNSFTSQVMAQIKLWTHPDKYPVGVHFLPKKLDESVAEAHLGKLNMKLTKLTEKQAQYLGMSCYCPFKPDHYRYLast
1 -2.780PB002104 Q72PH8_LEPIC/1-220 PB002104; Pfam-B_2104;  ali follow..  7.....................................................................................................................................................................KIQFSKIRSRSCPFMQQNKFRKAIVAILMPMILVVSFNCFGKAIVKKVYEVNDGFNIGSGLLAKFIKTLVMYFPFSILYFVGFFFDLILFNLSGNNPVGYNEYDENGKYVKAYEENGEKLLLSYSDFGKRLDIQFAKEGNSQNLIVAEPGKFFVEKDGKLEEIVVSSETVGSKTILKMAEQGKLKSTKVVDTKTLNDLEAKLVSE........................................... 219
2 -2.610PB003645 Q65HI2_BACLD/1-230 PB003645; Pfam-B_3645;  ali follow..  80.....................................................................................................................................................................KEVFKPASDDKPKESIQDYEQEYENQLKDILETIIGVEDV--SIVVNVDATSLKIFEKNRKTQETSETDKQGGKRTVSEMSSDEEIVIIKNGDKETPVVVQTKKPDIRGVLVVAQGVDNVQI-----------KKTIIEAVTRVLDVPSHRVAVA............................................................................................. 223
3 -2.420PB162065 _Gut.Meta.Jp.0089312_ gi|162832207|dbj|BABA01012502.1||1 (- 0:1326~0 complete)  ali follow..  1..............................................LIGIFFQKTLKALETVCEGAEVGFITITMEDVDLATADALKRAAASM--------------IGAQLLALESHRLSYEYYALSQRRELWTHDVGLFEYDRRGL-RYHHLSVSWKHHPPVVTAETTVLNQYLDG----HELADPVPPEMDRQFLEAIKEVSARRMISTYYLMG------------------EGFSGAESGKSWMNLSLKQLCAMKRHVFAGQNL--YARGACYHSFDQGSFG-RKPGFIAANAGLLTKDIYLRSVHKHAPQKLILAAAG--TPWYSAVSRKAIIIDGQEQLIIRMRDPLTNFEQTVVMTLDALPQRPPKTTLLIETSFQSETDCHIRVTDMGF------GEIFAATGK. 320
4 -2.170PB046158 _JGI.0336690_ 2004028347 [Human Gut Community Subject 8]  ali follow..  14  68.............................................................................................................................................KKKPHGKQTIKQLNAQGV-QLSNIKITDENIKSFDRRKYGIDYSLKKEVGADPPKYLVFFKAKDVDVMTAAFREYAGVELKKKQVKKPSVRKKLQ................................................................................................................................................................................. 163
5 -2.110HGC00915 gi|162810474|dbj|BABA01034235.1|2.0 TMP01234;  ali follow..  18  1...........................................................................................................................................................................................................................................................................................................................................................................................MSKKKRGEERMKEEDNILKKVGKKNSFKPEGY.. 33
6 -2.060PB012991 Q2RHT0_MOOTA/1-175 PB012991; Pfam-B_12991;  ali follow..  15  5.............................................................................................................................................EEVRTGWSRWDSL-------WPFLLFYCNFLKGVFLLRI----------------AVVDG-GGIGKHITARLRQEEVEILALGTNAAATVAMIKAG------ANEGATGERAIIYNAPRVEAITGSLAIILADAMLGELTPAMAA............................................................................................................................... 124
7 -1.950PB001934 Q6PSL5_CHLRE/821-1150 PB001934; Pfam-B_1934;  ali follow..  7.............SKQIPRMSLDLASTPLHERSTITSAFVKEGAVRSSRYGAPLPGCLPRWSLGRNARLLMV-IPMDAETPGGRLLRPQAQVMEE-------------------AIRHWATVLSVRLDLDAARGKLGPEACEMERQRFDGVIAMMERND---PTLVVTDSQAIDVVHPWTLDRSSGRPLVPITTFSIAMAYQGRLGLEALETLQD-GDRVLISEACNHNRITSACNDIGMVQIPNKLEAGKKLQIEHAFGREFPELESGGMDGLKLAIHCGG----------------MIDAQKMQQRMKDLHEAGVPVTNYGVFFSWAAWPDALRRALE......................................................................... 306
8 -1.920HGC00711 gi|162743779|dbj|BAAZ01020484.1|1.0 TMP00907;  ali follow..  28..........................................................................................................................................................................................................DERGAGTVLVVGVIAVLLAAA-VSGLIQAQAAAGRSRAAADLAALGGATALSSIVAPGDPCEAASRVARANGAEVTTCSVTGEDVVVE........................................................................................................................... 116
9 -1.890PB144506 _Gut.Meta.Jp.0101058_ gi|162866171|dbj|BABB01003836.1||1 (- 121:946~0 complete)  ali follow..  42...................................................................................................................IELGGNIEYSGNNFWGNRSNKKFPVFKYTHGRSASLKITIDENLFPLLSIKSNNGRLA----------IRIQDGTRIKPTQYVI----EGSSKTLKYLKTSGPDFEAQNAFSEDQLEIKISGSSDVKF-PHNVKLRLGEFSVSGSGDLVFADLDCKNLTSKVSGSGDITLKGKADEAR........................................................................................................................ 205
10 -1.800PB001823 Q5L7Q9_BACFN/1-326 PB001823; Pfam-B_1823;  ali follow..  109...........................................................................................................................................MFEDTQNGDYDYNDL---------IIHVKNTASNHAYQHPTETWQTI---------EIQPIALGS-TKTIKLGCILSDGSTHMISDDVRTDLFGGRQGFINTVNDNDPIRYKLASTNIKNYAMPKKEKTSAAWVAWFIEVDGKRMYAASSD---------------------IDYKSYDMVNKE---NMPYGLAVSNGNGTFSYPQEKNSLFETYPG--------------------SDWINGKVSSIGSFQKELVYKYCSGG---IGEDGKSH 318

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.