current user: public

If you have questions about the server, please let us know.

Query: [W] KOG3658 Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17) and related metalloproteases, from VFDB

Results of FFAS03 search in HGM_OVER
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560    .  570    .  580    .  590    .  600    .  610    .  620    .  630    .  640    .  650    .  660    .  670    .  680    .  690    .  700    .  710    .  720    .  730    .  740    .  750    .  760    .  770    .  780    .  790    .  800    .  810    .  820    .  830    .  840    .  850    .  860    .  870    .  880    .  890    .  900    .  910    .  920
# Score Template Links and tools%idFirst MSSPIRNRLQLVVTLIFCLFFENVNGLNNFIDNFETLNYRATHVANQVTRRKRSIDSAASHYQEPIGFRFNAYNRTFHVQLHPIDDSLFHEDHMSDVDGGYADIKPSHFLYEGYLKDDPNSHVHGSVFDGVFEGHIQTGEGRRYSIDKAAKYFERDDRPTQYHSIIYRDDEINHRKWRVKRDAENLSEQMQGCGFSSRVRREMTDVQNSGESTDFFTNYMTMGGRSKRANTLRDHDGLYFVRTCSLYMQADHKLYEHIRMKEGNNDPIRTREEIVSLFYNHIKAVNEIYEGTNFNGIKGLHFVIQRTSIYTPDSCDRGRAKTDSDNPFCEENVDVSNFLNLNSQRNHSAFCLAYALTFRDFVGGTLGLAWVASPQFNTAGGICQVHQRYNEGSRGWVYRSLNTGIVTLVNYGNRVPARVSQLTLAHEIGHNFGSPHDFPAECQPGLPDGNFIMFASATSGDKPNNGKFSPCSVKNISAVLAVVLKSMPVDPTRNASPVGIGKRNCFQERTSAFCGNQIYEPGEECDCGFSQADCDQMGDKCCVPHEARGNGGPGPCKRKPGAQCSPSQGYCCNPDTCSLHGKNEEKICRQESECSNLQTCDGRNAQCPVSPPKHDGIPCQDSTKVCSSGQCNGSVCAMFGLEDCFLTEGKADELCFLACIKDGKCTSSVHLPEFSANRTNFLQNMRKDKPGLILHPGSPCNNYKGYCDIFRKCRSVDANGPLARLKNLLFNKRTIETLTQWAQDNWWVVGVGGLVFLVIMALFVKCCAVHTPSTNPNKPPALNIYQTLTRPGTLIRQHRQRHRAAAGSVPPGPGAQPRSGAASAPSRTTPSARPSAPPLVAPQVAVAVPPGVVGPPIPLIATHPGSSSSTPAVIVLEPPPPYTAADPGSAMGGPRRGHRKNKRQTSSDAAGSSGNGGKKKGKLast
1 -5.980HGC00991 gi|163600283|dbj|BABF01000984.1|3.0 TMP01348;  ali follow..  19  23...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AYCG--------DCKCDAYIATINDNQENCCRVDGIKTVFCDNMCGIR---QCALEKG----VATC--------------GDCLDLERCP................................................................................................................................................................................................................................................................................................................................. 109
2 -4.590PB001232 gi|126647001|ref|ZP_01719511.1| hypothetical protein ALPR1_19713 [Algoriphagus sp. PR1]gi|126577049|gb|EAZ81297.1| hypothetical protein ALPR1_19713 [Algoriphagus sp. PR1]  ali follow..  10  2...................................................................IQTSFYQEKINEIISP---LSRSAFAYYRFTYEGTFFDQDVLVNK--IKVTPRSR------ERVFEGYIYIIEDLWYLASTRDYEVTMNPDLAYVPEIIDEKVQEVPDEVAKSESALEQLAKEQPTTRKEYRKMINEYEKEAMKEREEPEVIRESYYSIDSLAKKRELSYWDSIRPVPLT-EKEIEGYNRDDSLAVVEAAKVSEVDSVAKKARSKFRPLDFMNGATYNFGAGKSFGFKQNTKISFNTVEGFKLGMGLFYRKYQEEKLADSVNRIRKSFNIEPE-LRYGFSSNKFYGK-VDFRWSTTKPISGHTFGIEGGKYIYQFNGGDPINEQVNAFYSLLNYMKLYEQEFAKIYWAHRVNYGFNLTYANRHQLFNNINKEGREYTPNQPENVETDDQAFADHDILKLNASIEWRPGVKYGIRNGRKYPITSNSPLIKLSYNKAF--GGISNSESSAD............................................................................................................................................................................................................................................................................................................................................................................................................ 512
3 -4.530HGC00928 gi|162868028|dbj|BABB01001979.1|3.0 TMP01255;  ali follow..  11  9...........................................................................................................................................................................................................................MARTATEKLEMRGQSVTVENIGKTVTDGFEKVSNNVNDFISSDKPRNFFQKLADVFVLVIGFIKFFIILAGIFLLPPLVLVVFILVVVTF----------------------ALLMGGAGFIYNLSPFGADLINGAPLSMAIMGCIGTILFIGIPIFSLIYAICSQLFKIRPLPTQARWILLALWLISFI----------LCGVYIHQSGHNYGV-HDWNRNA................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 206
4 -4.040PB002589 gi|91201099|emb|CAJ74158.1| hypothetical protein [Candidatus Kuenenia stuttgartiensis]  ali follow..  2..........................................................................KEELVRCIWFGQHIEKKNLRTDDGLR-------EILSPGWWNNEEGPDFKHAEFF--LEGKGLIRGSVEIHVFASDWIHHKHENQKTYDAVCLH---VMWNDLKGRCVKNFSGKVIPQITLSLYLEAELDEIIETIDVGSYIGNKQVIPGYCNLEMRKQKITQQWIGGFLDYAGDEERVLYEAIMESLGYKNNKKPFLMLASLV---AETIQSFVPEYT-EKKIIAQSLLLGMAGLLPLNEEETKRFDDETIQYFDRIFSTWQGIKPKIHQTPLTRESWSYTGIRPANFPDRRIVAIANILSEHLDNGLFRYILRIFQKRDDTKKNTRGFKSFVNEFLSPFLETHDAYWSYR---YTPGGKKLNKPQKLLGKER-NVIIPVMLVYARKHNDKALEERLHYIYRNYTPHPSTSVTKSMVSNKVIHSARRQQGLYQLFKDFC----ENDTISCKCA.......................................................................................................................................................................................................................................................................................................................................................................................................... 471
5 -3.800PB050904 Q64SA2_BACFR/1-230 PB050904; Pfam-B_50904;  ali follow..  1MKSRIISLGLVASLVCLLPQVAEAQIAASNPLEWTALAEGNELINGQIEKQIKGQTQTALLQNSIAT-QIHKWEKQYNSYLKTASGYASSLKACTHLYNDGVRIFLTLGKLGKAIQNNPQGIVASMNMNNLYIETATELVSDAVAKGSNENMLTGAERSKTLWALNDQLSDFS............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 181
6 -3.740PB042013 A7V626_BACUN/1-162 PB042013; Pfam-B_42013;  ali follow..  1MKRNYFFTMLAAVLLAVAGANAQESA-AELAGIWQLC-----------HYVSEIPDVPGILKPSNTFKVLSDDGRIVNFTMIPGKDAIITGYGTYQQLTDNS-----------YKESIEKNIHLPMLDHKDNILEFEIGDDGVMYLKYFIAKDLNGNELNTWFHETWKRVGMPAK........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 156
7 -3.560PB005346 A0R807_PELPD/1-258 PB005346; Pfam-B_5346;  ali follow..  11  4....................................................................................................................................................................................................................................................SLFWAIDKNQFHHNWMGMSQINQTTSGNFYDQVLENFTDALDCLTAHLMLECSEVLGVKPANLISIVNRTRPCGRNLYLLWQQHHTDLAQRLNNLNFMVLQSRQQSLLLLCYDHVRLE---------HHLSHPGIRTLLHKAGYKDDADCEGMLLELRSRIGGNNS-------------FPHEIGLFIGYPKDVAAFMGLVRLPRLWKIYGNPARSLAL--EQYRCCRNKMGAILARGTSKTLEIDRSDHPFFCQTDENDY................................................................................................................................................................................................................................................................................................................................................................................................................................. 254
8 -3.310PB015266 gi|154494998|ref|ZP_02034003.1| hypothetical protein PARMER_04044 [Parabacteroides merdae ATCC 43184]gi|154085548|gb|EDN84593.1| hypothetical protein PARMER_04044 [Parabacteroides merdae ATCC 43184]  ali follow..  1MKRIVSMMVIFTLLLGGMTHVQAQTSKAAXXXXXXXXXXXXXXXRLAKDAVMGEEAFNNAMNDGQAMVQIASNSPNVYLSMSVQGIFISATVNLVLYSGTNPNFSGNNLTMNGTLLPYSDSNV--------FQGT................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 195
9 -3.270HGC00947 gi|162844524|dbj|BABA01000185.1|4.0 TMP01280;  ali follow..  1MRKLVKLILLCLIAYPIISIVSSCSEEEDQCYLYKRVVNDTLDSLTITAFGTDSIILNNQKRVHGLSLPLRYTADSTVLVFHYSKDVKIKKDTIVIRQKNTPYFLSMDC---GYQMKQSITGR----------------SYSRHLLDSIYIQTAEVSIYGTENLKLFYRN................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 166
10 -3.220PB019279 Q5LE73_BACFN/1-147 PB019279; Pfam-B_19279;  ali follow..  10  1MKTLTFKYLKLFLLAVAMINLTSCEIEIDDFDNIGGSYYNKSLDLCSRPWADTFYDADGNYCYQELNFYLDRHGEDYIRVEYPNGRYSESVYSFTWNWEDRSQYSLRMVYGPGDVSYLDDVWIRGNVLSGYLDGHDNYVDFT............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 145

FFAS is supported by the NIH grant R01-GM087218-01
1 4 2 3 1 8   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster

Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.