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Query: [HE] COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases, from VFDB

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNLAWLQGLSLGLLSPPAPALLIFRSFTMAKVLVSDSIDQVGIDILKQVAQVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAGSQLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSVKESKWERKQFIGTEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGCTLVDLDLLFSEADFITLHIPKTPETANLINAETLAKMKPTARIINCSRGGIIDEEALVTAIETAQIGGAALDVFAQEPLGESRLREFSNVILTPHLGASTEEAQVNVAVDVAEQIRDVLLGLPARSAVNIPGLTPDVMEKLRPYLKLAETLGTLVGQLAGGRIDRLTVCLQGDLAEYTNSQPLVVAAIKGLLSQALRERVNYVNAAIEAKERGIRVIETKDASVRDYSGSLHLKATGTMGEHSATGALLSNGEIRITDVDEFPINVPPNNYMLFTLHRDMPGIIGKIGSLLGSFNVNIASMQVGRKIVRGDAIMALSLDDPLPDGLLSEITKVAGIRDAYTVKLLast
1 -4.940sp|Q9UBI9|HDC_HUMAN Headcase protein homolog OS=Homo sapiens GN=HECA PE=1 SV=1  ali   12  24......................................................................................................DYQKVVCNNEHCPCSTWMHLQCFYEWESSILVQFNCIGRARSWNEKQCRQNMWTKK---GYDLAFRFCSCCGQGHLKKDT.................................................................................................................................................................................................................................................................................................................................................................................... 101
2 -4.460tr|E9PGC6|E9PGC6_HUMAN Uncharacterized protein OS=Homo sapiens GN=PRCC PE=4 SV=1  ali   14  1....................................................................................................................................................................................................................................................................AFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYYQGLQQHLGHSPLRGIMRFLNSKSGKRTCFVPSFD.................................................................................................................................................................................................................. 84
3 -4.420sp|P21817|RYR1_HUMAN Ryanodine receptor 1 OS=Homo sapiens GN=RYR1 PE=1 SV=3  ali   15  12...................................................................................................................................................QMLMPVSWSR-------MPNHFLQV--------ETRRAGERLGWAVQCQEPLTMMALHIPEENRCMDILELSERLDLQRFHS----HTLRLYR----AVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGY--------------DLLISIHLESACRSRRSMLSEYIV........................................................................................................................................................................................................................................ 150
4 -4.240sp|Q15413|RYR3_HUMAN Ryanodine receptor 3 OS=Homo sapiens GN=RYR3 PE=1 SV=3  ali   12  1..........................................................................................................................................LKNAMPLSAAIFRSEEKNPVPQCPPRLDVQTIQPVLWSRMPNSTERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLMRFHY----HTLRLYS----AVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGF--------------DLLISIHL-----ASAKERKLMMKNEYIIPITSTTRNIRLFPDESKRHGLPGVGLRTCL..................................................................................................................................................................................................... 198
5 -4.020sp|Q9HCC9|LST2_HUMAN Lateral signaling target protein 2 homolog OS=Homo sapiens GN=ZFYVE28 PE=1 SV=3  ali   10  1..............................................................MMNRFRKWLYKPKRSDPQLLARFYYADEELNQVAAE---LDSLDGRKDPQRCTLLVS----QFRSCQDNVLNIINQIMDECIPQDRAPRDDNLAGQLWFGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGALRDQALRDLNTYTEKMREALRHFDFAEFELSYVSAMVPVKSPREYYVQQEVIVLFC---------ETVERALDFGYLTQDMIDDY--EPAL---------MFSIPRLA-------------IVCGLVVY-----ADGPLNLDRKVEDMSELFRPFHTLLRKI................................................................................................................................................................................................. 267
6 -3.960sp|Q8WV92|MITD1_HUMAN MIT domain-containing protein 1 OS=Homo sapiens GN=MITD1 PE=1 SV=1  ali   14  12...............................................................................................................................................................................................EVWIEDPYIRHTHQLYNFLRFCEM-KRPCKVKTIHLLTSLDEGIEQVQQSRGLQEIEE-----SLRSHGVLLEVQYSSSIHDREIRGRGLDYFKKPQ.......................................................................................................................................................................................................................................................................... 113
7 -3.840sp|Q8N6M6|AMPO_HUMAN Aminopeptidase O OS=Homo sapiens GN=AOPEP PE=1 SV=2  ali   12  16.....................................................................................................LDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVSEEFRNQIVRELVTLPANRWREQL----DYYARCSQAPGCGEL........................................................................................................................................................................................................................................................................................................................................................................................ 88
8 -3.790sp|Q9NT68|TEN2_HUMAN Teneurin-2 OS=Homo sapiens GN=ODZ2 PE=1 SV=3  ali   13  52......................................................................QNPIVPETQVLHEEIELPGSNVKLRYLS-------SRTAGYKSLLKITMTQSTVPLNLIRVHLMVAVEFQKSFQASPNLAYTFIWDKTDAYGQRVYGLSDAVVSVG.......................................................................................................................................................................................................................................................................................................................................................................................... 153
9 -3.790sp|A4D1E1|Z804B_HUMAN Zinc finger protein 804B OS=Homo sapiens GN=ZNF804B PE=1 SV=2  ali   13  1.......................................................................................................................................................................................................................QAHFSPISFSTLTPTIIPAHPTFLAGHPLHLVAATPFHPSHITLQPLPPTAFIPTLFGPHLNPATTSIIHLNPLI-QPVFQGQDFCHHSCSSQMQQLNEVKEALNVSTHL..................................................................................................................................................................................................................................... 109
10 -3.770sp|Q8IYH5|ZZZ3_HUMAN ZZ-type zinc finger-containing protein 3 OS=Homo sapiens GN=ZZZ3 PE=1 SV=1  ali   9  4......................................................................................................................................................................................................................................FESDHVALKHNKDYQRLLQTIAVLEAQRSQAVQDLESLGRHQREALKNPIGFVEKLQKKADIGLPYPQRVVQLPEI........................................................................................................................................................................................................................................................ 79
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 8 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]