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Query: [R] COG4624 Iron only hydrogenase large subunit, C-terminal domain, from VFDB

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDALIRPPMSFFADLPKDNKKCIKIGSPLALSLSDCLACSGCVSADEAGALSEDLSFVLDLSPQTSFVLSPQSKINIFNLYREDGMEYREFEAVLSSFLRSKFNIHRIVDTSYLRSKIYEETYREYMATNHLIVSACPGVVTYIERTAPYLIGYLSRVKSPQQMAFSLVKGSRTVSVMPCQDKKLENGRDGVKFDFILTTRGFCKALDSLGFRRPARASGKSLCSMEEAETTQWNIGTSSGGYAEFILGKHCVVETREIRNGIKEHLLDDGRTISQITGLENSINYFKSSKTKGPRHKMTEIFLCKNGCIGGPGQERVNDVEMDIREYDRNGREQPRIFYSSPGLEEKRVFREVKAKRVDLRVDWLast
1 -6.900sp|O43299|K0415_HUMAN Protein KIAA0415 OS=Homo sapiens GN=KIAA0415 PE=1 SV=2  ali   1LREVAFEYCQRLIEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRSLSCLKALHGRVRGDPAVRVLLPLAHFFLSHGEAAAVDSEAVYQHLFTRIPVEQFHSPMLAFEFICRDNLHLFSGHLSTLRLSFPNLFKFLAWNSPPLTSEFVALLPALVDAGTALEMLHALLDLPCLTAVLDLQ................................................................................................................................................................................. 191
2 -5.370sp|Q504Y0|S39AC_HUMAN Zinc transporter ZIP12 OS=Homo sapiens GN=SLC39A12 PE=2 SV=3  ali   10  7.DHPPHNHSRSLIKTLLEKTGCPRRRNGMQGDCNLCFEPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLLSLRQDE-------DSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLPQLAAMII----TLSLQGVCLGQG-NLPSPDYFTEYILRLSELDQLLNT............................................................................................................................................................ 211
3 -5.170sp|Q5T4S7|UBR4_HUMAN E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens GN=UBR4 PE=1 SV=1  ali   1.................................TKCYGCAHCITLLRALATNPALRHILVSQGLIRELFD-QLMCLLTRDNPEATQQMNDLIIGKVSTALKGHWANPDLASSLQYEMLLLTDSISKEDSELRLRCALSLFLMAVNIKTPVVVENI---------------------TLMCL........................................................................................................................................................................................ 148
4 -5.140sp|Q9HCE0|EPG5_HUMAN Ectopic P granules protein 5 homolog OS=Homo sapiens GN=EPG5 PE=2 SV=2  ali   11  72..DTMPKQYVNREEQTTLHLEC------RGSSGKKCQGAAVVTVQFEGMHKNEAISQQLHVLRKEVKQLQAEAAKPPSLNIVEAAVHAENLITALVNAYIQKVGFFTIVDYVSDETQRHPPTRQFFTSCIEILGQ---VFISGIKSECRKVLETLSPFFTPNAAPAEFIQLYEQVV-------KFLSEDNSDMIFMLLTKFDLKQWLSATKPPLSDRTR-----------------------LLESIHLALTAWGLEPDEDILMPFNLFCKHWTYLLL--DILRLLMQSSAEQLLSPECWKATLRALGC........................................................ 365
5 -5.020sp|Q5VZ72|IZUM3_HUMAN Izumo sperm-egg fusion protein 3 OS=Homo sapiens GN=IZUMO3 PE=2 SV=4  ali   13  112.....................CSEDCIVVEGPILDCWTCLRMTNRCFKGEYCGDEDPRKAENREIAL.......................................................................................................................................................................................................................................................................................................... 157
6 -5.010sp|Q8ND82|Z280C_HUMAN Zinc finger protein 280C OS=Homo sapiens GN=ZNF280C PE=1 SV=1  ali   12  8............IHKCIECHSKIKDFASHFSIYIHCSFCTNCNKAFVNHMMSSHSNHPGKRFCIFKKHSGTLRGITL................................................................................................................................................................................................................................................................................................ 75
7 -5.000sp|O75592|MYCB2_HUMAN Probable E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens GN=MYCBP2 PE=1 SV=3  ali   10  114............KIACSKTHPCGHPCG------GVK-HCLPCLHGC............................................................................................................................................................................................................................................................................................................................... 143
8 -4.910sp|O43301|HS12A_HUMAN Heat shock 70 kDa protein 12A OS=Homo sapiens GN=HSPA12A PE=1 SV=2  ali   5...............................................................................................................................................................DPAVIKVRRSPLTYGVGVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADVALGELVKRSYTPAKPSQLVIVINIYSSEH-ITDPGVKKCGTLRLDLTGTSGTAVPARREIQTLMQFGDTEIKATAIDIATSKSVKVGIDFLN............................................................. 155
9 -4.870sp|Q8NCS7|CTL5_HUMAN Choline transporter-like protein 5 OS=Homo sapiens GN=SLC44A5 PE=2 SV=2  ali   11  1....................RCTSPSVLLNLQ---CPTTQICVSKCPE------------------------------KFLTYVEMQLLYTKDKSYWEDYRQFCKTTAKPVKSLTQLLLDDDCPTAIFPSKPFLQRCPDFSTKNGTLTIGSKMMFQDGNGGTRSVVELGIAANGI.............................................................................................................................................................................................. 123
10 -4.820sp|Q86XX4|FRAS1_HUMAN Extracellular matrix protein FRAS1 OS=Homo sapiens GN=FRAS1 PE=2 SV=1  ali   12  235............................KHLNLKSCVVCGGSVTADFQVRDSAQSFLTVHVPLYVSYIYVTHTEMEFSFFYDTVLWRTGIQTDSVLSARLQRLVIEFKTHAKFRGQFVMEHHTLPEVKSFVLTPDHLGGIEFDLQ-----LLWSAQTFDSPHQTSSYNRKDYYTIYLIPCTVQPTQPWVDPGEKPLACTAHAPERFLIPIAFQ--------------QTNRPVPVVYSLNTEFQLCNNEKVFLMDPNTSDMSLAEMDYKGAFS-QILYG--RVLWNPEQNLNSAYKLQLEKVYLCTGGCIQPNKHLKHRFLLLDRNQPEVTDKYFHDVPFEAHFASELPDFHVVSNMPVEAGHQW 627

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.