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Query: [G] COG0120 Ribose 5-phosphate isomerase, from VFDB

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTERNTSTDSPEKRAAGIAAAGLVSSGMLVGLGTGSTVAYTIKELGRRVREEGLDILGVVTSYQSEMLAIEAGIRLTTLAQHPELDLAIDGADQIDSELRAIKGGGAAHTREKIVSVSARRFVVVADESKTSKQLDKLVPVEVLPFAKEPVVKKIRELGGKPQLRSAVKKDGPVITDNGNFVLDVEFGVIKDPEALALQLSSIPGVVEHGIFCNVSELYIGNKDGAIKIITRQKLast
1 -94.3001lk5_A mol:protein length:229 D-Ribose-5-Phosphate Isomerase  ali model follow..  42  2.......NVEEMKKIAAKEALKFIEDDMVIGLGTGSTTAYFIKLLGEKLKRGESDIVGVPTSYQAKLLAIEHDIPIASLDQVDAIDVAVDGADEVDPNLNLIKGRGAALTMEKIIEYRAGTFIVLVDERKLVDYLCMPVPIEVIPQAWKAIIEELSIFNAKAELRMGVNKDGPVITDNGNFIIDAKFPRIDDPLDMEIELNTIPGVIENGIFADIADIVIVGTREGVKKLER.. 229
2 -93.9003l7o_A mol:protein length:225 Ribose-5-phosphate isomerase A  ali model follow..  38  1........MEELKKIAGVRAAQYVEDGMIVGLGTGSTAYYFVEEVGRRVQEEGLQVIGVTTSSRTTAQAQALGIPLKSIDEVDSVDVTVDGADEVDPNFNGIKGGGGALLMEKIVGTLTKDYIWVVDESKMVDTLGFRLPVEVVQYGAERLFREFEKKGYKPSFREY--DGVRFVTDMKNFIIDLDLGSIPDPIAFGNMLDHQVGVVEHGLFNGMVNRVIVAGKDGVRILEANK 225
3 -91.7004gmk_A mol:protein length:228 Ribose-5-phosphate isomerase A  ali model follow..  37  3.......NQDELKQLVGTKAVEWIKDGMIVGLGTGSTVKYMVDALGKRVNEEGLDIVGVTTSIRTAEQAKSLGIVIKDIDEVDHIDLTIDGADEISSDFQGIKGGGAALLYEKIVATKSNKNMWIVDESKMVDDLGFPLPVEVIPYGSGTVFKRFEEKGLNPEFRKN-EDGSLLHTDSDNYIIDLHLGKIENPKELGDYLINQVGVVEHGLFLDIVNTVIVGRQDGPEVLEAR. 228
4 -89.1001uj4_A mol:protein length:227 ribose 5-phosphate isomerase  ali model follow..  42  3......RPLESYKKEAAHAAIAYVQDGMVVGLGTGSTARYAVLELARRLREGELGVVGVPTSRATEELAKREGIPLVDLPPEG-VDLAIDGADEIAPGLALIKGMGGALLREKIVERVAKEFIVIADHTKKVPVLGGPVPVEIVPFGYRATLKAIADLGGEPELRMD--GDEFYFTDGGHLIADCRFGPIGDPLGLHRALLEIPGVVETGLFVGMATRALVAGPFGVEELLP.. 227
5 -89.0003ixq_A mol:protein length:226 Ribose-5-phosphate isomerase A  ali model follow..  40  2.......SNEDLKLKVAKEAVKLVKDGMVIGLGTGSTAALFIRELGNRIREEELTVFGIPTSFEAKMLAMQYEIPLVTLDEYDVDIAFDGADEVEETTLFLIKGGGGCHTQEKIVDYNANEFVVLVDESKLVKKLGFPIPVEVIPSAYRVVIRALSEMGGEAVIRLGDRKRGPVITDNGNMIIDVFM-NIDDAIELEKEINNIPGVVENGIFTKVDK-VLVGTKKGVKTLKK.. 226
6 -88.4003hhe_A mol:protein length:255 Ribose-5-phosphate isomerase A  ali model follow..  37  10TQGPGSMNVQQLKKMAALKALEFVEDDMRLGIGSGSTVNEFIPLLGERVANG-LRVTCVATSQYSEQLCHKFGVPISTLEKIPELDLDIDGADEIGPEMTLIKGGGGALLHEKIVASASRAMFVIADETKMVKTLGFALPIEVNPFGIHATRIAIDNLGLSGEITLRMNGDDPFKTDGGHFIFDAFWGRILQPKLLSEALLAIPGVVEHGLFLGLASRAIVAMADSIKVLEPFD 248
7 -88.4005uf2_A mol:protein length:231 Ribose-5-phosphate isomerase A  ali model follow..  34  2....AMTTQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSGKK---IKGAVSTSKKSGELLARYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHLNEKIVASASEKFVCIADESKYVSRLGFPLPVEAVESARSLVSRKLLAMGGQPELR------IGYTTFYGNQIVDVHGLNIDQPLTMEDEINKITGVLENGIFARAADVLILGTEEGAKVIYPCQ 224
8 -87.9006mc0_A mol:protein length:224 Ribose-5-phosphate isomerase A  ali model follow..  37  2.......AMSELKIKAAKAAIAYIEDDMVIGVGTGSTVNFFIKELAAIKHK---IEACVASSKATEALLRAEGIPVIDLNSVQDLPIYVDGADEVNERGEMIKGGGGALTREKIVANVATQFICIVDESKVVKRLGFPVAVEVIPMARSFVARQIVKLGGDPEYR------EGFVTDNGNIILDVFNLSFSTPMALEDSLNVIPGVVENGVFAKLADKVLVASASGVNNLK... 218
9 -87.4003enq_A mol:protein length:235 Ribose-5-phosphate isomerase A  ali model follow..  39  14..GRGSMTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTMSEE---IKGAVSSSVASTEKLEALGIKIFDCNEVASLDIYVDGADEINADREMIKGGGAALTREKIVAAIADKFICIVDGTKAVDVLGFPLPVEVIPMARSYVARQLVKLGGDPCYR------EGVITDNGNVILDVYGMKITNPKQLEDQINAIPGVVTVGLFAHRADVVITGTPEGAKIEE... 235
10 -87.4001m0s_A mol:protein length:219 Ribose-5-Phosphate Isomerase A  ali model follow..  37  2.......NQLEMKKLAAQAALQYVKADRIVGVGSGSTVNCFIEALGTIKDK---IQGAVAASKESEELLRKQGIEVFNANDVSSLDIYVDGADEINPQKMMIKGGGAALTREKIVAALAKKFICIVDSSKQVDVLGFPLPVEVIPMARSQVGRKLAALGGSPEYR------EGVVTDNGNVILDVHNFSILNPVEIEKELNNVAGVVTNGIFLRGADVVIVGTPEGAKVID... 219
11 -87.4001ks2_A mol:protein length:219 protein EC1268, RPIA  ali model follow..  39  2.......TQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTM---KGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGFPLPVEVIPMARSAVARQLVKLGGRPEYR------QGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRADVALIGTPDGVKTIVK.. 219
12 -87.2001xtz_A mol:protein length:264 Ribose-5-phosphate isomerase  ali model follow..  33  12..ESLGNPLEDAKRAAAYRAVDKFDDHKIIGIGSGSTVVYVAERIGQYLHDPKSKFICIPTGFQSRNLILDNKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSTSAKTFIVVADSRKKSPKHRQGVPIEIVPSSYVRVKNDLLEQLHAEKRQGGSAKAGPVVTDNNNFIIDADFGEISDPRKLHREIKLLVGVVETGLFIDNASKAYFGNSDGSVEVTEK. 258
13 -87.1003kwm_A mol:protein length:224 Ribose-5-phosphate isomerase A  ali model follow..  35  1MFFNKKNNQDELKKLAATEAAKSITTEITLGVGTGSTVGFLIEELVNYRDKI---KTVVSSSEDSTRKLKALGFDVVDLNYAGEIDLYIDGADECNNHKELIKGGGAALTREKICVAAAKKFICIIDESKKVNTLGFPLPIEVIPMARSYIARQIVKLGGQPVYR------EQTITDNGNVILDVYNLKIDNPLKLETELNQITGVVTNGIFLKPADTVIMATKDSNIVV.... 223
14 -84.5002f8m_A mol:protein length:244 ribose 5-phosphate isomerase  ali model follow..  32  2.......AMDSLKKIVAYKAVEYVQSNMTIGLGTGSTVFYVLERIDNLLKSGKLDVVCIPTSIDTELKARKLGIPLTTLEKHSNIDITIDGTDEIDLNLNLIKGRGGALVREKLVASSSSLLIIIGDESKLCTNGTGAVPIEILTFGYEKIIENLLKIYTLKGCTIRKRNGEIFITDNKNYIVDFFFTEIQDLLETCTRIKMTTGVVDHGIFVNMTNVALISKHDGTVLTLNKK 236
15 -83.9004x84_A mol:protein length:231 Ribose-5-phosphate isomerase A  ali model follow..  36  4.......NQDQLKQAVAQAAVDHIDSKSIVGVGTGSTANFFIDALARHKAE---FDGAVASSEATAKRLKEHGIPVYELNTVSELEFYVDGADESNERLELIKGGGAALTREKIVAAVAKTFICIADASKLVPILGFPLPVEVIPMARSHVARQLVKLGGDPVYR------EGVLTDNGNIILDVHNLRIDSPVELEEKINAIVGVVTNGLFAARADLLLLGTADGVKTLKA.. 225
16 -83.3003u7j_A mol:protein length:239 Ribose-5-phosphate isomerase A  ali model follow..  35  6...TLLMTQDELKRLVGEAAARYVPQGAVIGVGTGSTANCFIDALAAV---KDRYRGAVSSSVATTERLKSHGIRVFDLNEIESLQVYVDGADEIDESGAMIKGGGGALTREKIVASVAETFVCIADASKRVAMLGFPLPVEVVPMARTAIGRRLAALGGVPVLR-VKQDGTPYVTDNGNEILDVKGLRIDDPRALEAAINGWPGVVTVGLFAQRADLCLLGTEHGVETLRYAA 238
17 -78.3004nml_A mol:protein length:275 Ribulose 5-phosphate isomerase  ali model follow..  36  1.....MNPQDKAKQAVGYFAVDYVRSGMKVGLGTGTTAKFVVERIGQRMQEGSLDLLCVPTSEATRKQAESLGIPLTTLDGIDCLDVAIDGADEIPPTLGLVKGRGGALLREKMIAAAAKTFIVAADETKLVSNGIGALPVEVVVFSGSHTKRLLKRHGGRAEFRKRAGEEDRFVTDNGNYIVDLYFTEVPDLHEMDKELKSIPGVVETGFFLDLASVCLIGKADGVATLTAER 258
18 -10.5003cdk_B mol:protein length:219 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B  ali model follow..  16  2......NAMKEARKRMVKRAVQEIKDGMNVNLGIGMPTLVANEIPDGVHVMLQSENGLLGIGPYPLEGTEDADLINAGKERGGHIDLAILGGMEVSEQGDLVKGMGGAM-----LVNGAKRIVVIMEHVN........................................................................................................ 150
19 -10.2003rrl_B mol:protein length:207 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B  ali model follow..  21  1...........MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVDADLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLIKGMGGAM-----LVHGAKKVIVIMEHCN........................................................................................................ 143
20 -10.0005dbn_B mol:protein length:223 Acetate CoA-transferase subunit beta  ali model follow..  20  2..........DAKQRIARRVAQELRDGDIVNLGIGTMVANYLPEGIHITLQSENGFLGLGPVTTAHPDLVNAG-MSFALIRGGHIDACVLGGLQVDEEANLVPGMGGAM-----LVTGSRKVIIAMEHCA........................................................................................................ 143
21 -9.4705mzw_D mol:protein length:248 Glutaconate CoA-transferase family, subunit B  ali model follow..  15  1.PHMSATLDITPAETVVSLLARQIDDGGVVATGVASPLAILAIAVARATHAPDLTYLSEDLGYLDGRSAEITIPDLFDHARRGRVDTVFFGAAEVDAEGRTFPGVAGAA-----LRQWVRRPVLLVSRRNLVPEVQV-LISDLGVFELGASGARLLARHPWASAAH--------IAERTGFAFQVSEALSVTSLPDARTVAAIRAIDPHGYR...................... 242
22 -9.4101poi_B mol:protein length:260 GLUTACONATE COENZYME A-TRANSFERASE  ali model follow..  13  6..........TNKEMQAVTIAKQIKNGQVVTVGTG--LPLIGASVAKRVYAPDCHIIVMAHCGCIWPNVRFVGFEINEYLHKANRLIAFIGGAQIDPYGNVFTGSGGAN-----IATYSNTIIMMQHEKRRF--------MNKIDY-VTSPGWIDGPGGRERLGLPGDVGPQLVVTDKGILKFDEKTKRM--------YLAAYPTSSPEDVLENTGFDLDVSKAVELEAPDPAV 242
23 -9.3006con_B mol:protein length:250 CoA-transferase subunit beta  ali model follow..  11  3..........TRAEVCAVACAELFRDAGEIMISPMTNMASVGARLARLTFAPDILLTDGEAQLLADTPALGKTGAPNRIEGWMPFGRVFEGANQVDRYGNQMFGVRGSP-----NTINHATSYWVGNHCKRV--------VEAVDV----VSGIGYDKVDPDNPAFRFVNVYRVVSNLGVFDFG--------GPDHSMRAVSLPGVTPGDVRDATSFEVHDLDA.......... 219
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.