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Query: [E] COG0169 Shikimate 5-dehydrogenase, from VFDB

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASQIDQYAVFGNPINHSKSPFIHTLFARQTQQSMIYTAQCVPVDGFTEAAKHFFAQGGRGCNVTVPFKEEAYRFADRLTERARLAGAVNTLKKLDDGEILGDNTDGEGLVQDLLAQQVLLKGATILLIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSYDVIINSTSASLDGELPAIDPVIFSSRSVCYDMMYGKGYTVFNQWARQHGCAQAIDGLGMLVGQAAESFMLWRGLRPGTKQILRELRKNLEGALLast
1 -103.0003pgj_A mol:protein length:302 Shikimate dehydrogenase  ali model follow..  100  19MASQIDQYAVFGNPINHSKSPFIHTLFARQTQQSMIYTAQCVPVDGFTEAAKHFFAQGGRGCNVTVPFKEEAYRFADRLTERARLAGAVNTLKKLDDGEILGDNTDGEGLVQDLLAQQVLLKGATILLIGAGGAARGVLKPLLDQQPASITVTNRTFAKAEQLAELVAAYGEVKAQAFEQLKQSYDVIINSTSASLDGELPAIDPVIFSSRSVCYDMMYGKGYTVFNQWARQHGCAQAIDGLGMLVGQAAESFMLWRGLRPGTKQILRELRKNLEGAL 296
2 -101.0001nyt_A mol:protein length:271 Shikimate 5-dehydrogenase  ali model follow..  50  1....METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDC-AVTITNRTVSRAEELAKLFAHTGSIQALSMDELGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELS... 271
3 -98.8003pwz_A mol:protein length:272 Shikimate dehydrogenase 3  ali model follow..  42  2....SDRYAVIGRPINHTKSPLIHGLFAQASNQQLEYGAIEGSLDDFEAQVLQFRSEGGKGMNITAPFKLRAFELADRRSERAQLARAANALKF-EDGRIVAENFDGIGLLRDIEENGEPLRNRRVLLLGAGGAVRGALLPFLQAGPSELVIANRDMAKALALRNELDHSRLRISRYEALEGQSFDIVVNATSASLTADLPPLPADVLGEAALAYELAYGKGLTPFLRLAREQGQARLADGVGMLVEQAAEAFAWWRGVRPDTRAVINQLTIPLE... 272
4 -98.5001p74_A mol:protein length:272 Shikimate 5-dehydrogenase  ali model follow..  46  1....MDLYAVWGNPIAQSKSPLIQNKLAAQTHQTMEYIAKLGDLDAFEQQLLAFFEEGAKGCNITSPFKERAYQLADEYSQRAKLAEACNTLKKLDDGKLYADNTDGIGLVTDLQRLNWLRPNQHVLILGAGGATKGVLLPLLQAQ-QNIVLANRTFSKTKELAERFQPYGNIQAVSMDSILQTYDLVINATSAGLSGGTASVDAEILKLGSAFYDMQYKGTDTPFIALCKSLGLTNVSDGFGMLVAQAAHSFHLWRGVMPDFVSVYEQLKKAM.... 271
5 -97.9004omu_A mol:protein length:283 Shikimate dehydrogenase  ali model follow..  57  1....MDQYVVFGNPIGHSKSPLIHRLFAEQTGQDLEYATLLAPLDEFSDCARGFFKQG-SGGNVTVPFKEEAFRLCDSLTPRARRAGAVNTLSKLADGTLQGDNTDGAGLVRDLTVNGVELAGKRILILGAGGAVRGVLEPILAHKPQSLVIANRTVEKAEQLAREFDELGPVVASGFAWLQEPVDVIINATSASLAGELPIADSLVEAGRTVCYDMMYGKEPTPFCQWATKLGAAKVLDGLGMLAEQAAEAFFIWRGVRPDTAPVLAELRRQLARG. 274
6 -92.4002egg_A mol:protein length:297 Shikimate 5-dehydrogenase  ali model follow..  31  13QGHMEKVYGLIGFPVEHSLSPLMHNDAFARLGIPARYHLFSVEPGQVGAAIAGVRALGIAGVNVTIPHKLAVIPFLDEVDEHARRIGAVNTIIN-NDGRLVGYNTDGLGYVQALEEENITLDGKRILVIGAGGGARGIYFSLLSTAAERIDMANRTVEKAERLVREGDERRSFSLAEAETRLAEYDIIINTTSVGMHPEVQPLSLERLRPGVIVSDIIYNPLETKWLKEAKARGA-RVQNGVGMLVYQGALAFEKWTGQWPDVNRMKQLVIEALRR.. 291
7 -92.2003don_A mol:protein length:277 Shikimate dehydrogenase  ali model follow..  33  2......KFAVIGNPISHSLSPLMHHANFQSLNLENTYEAINVPVNQFQDIKKIISEKSIDGFNVTIPHKERIIPYLDDINEQAKSVGAVNTVLV-KDGKWIGYNTDGIGYVNGLKQIYEGIEDAYILILGAGGASKGIANELYKIVRPTLTVANRTMSRFNNWSLNINK---INLSHAESHLDEFDIIINTTPAGMNGNTSVISLNRLASHTLVSDIVYNPYKTPILIEAEQRGN-PIYNGLDMFVHQGAESFKIWTNLEPDIKAMKNIVIQKLKGEL 269
8 -92.0001vi2_A mol:protein length:300 Shikimate 5-dehydrogenase 2  ali model follow..  30  5VTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVN-DDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEKALAFAQRVNENTDADQQAFAEALASADILTNGTKVGMKPESLVNDISLLHPGLLVTECVYNPHMTKLLQQAQQAGC-KTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGAEGG. 293
9 -91.7001nvt_A mol:protein length:287 Shikimate 5`-dehydrogenase  ali model follow..  30  7INAKTKVIGLIGHPVEHSFSPIMHNAAFKDKGLNYVYVAFDVLPENLKYVIDGAKALGIVGFNVTIPHKIEIMKYLDEIDKDAQLIGAVNTIKI-EDGKAIGYNTDGIGARMALEEEIGRVKDKNIVIYGAGGAARAVAFELA--KDNNIIIANRTVEKAEALAKEIAEKLNVKFSGLDVDLDGVDIIINATPIGMYPNEPIVKAEKLREDMVVMDLIYNPLETVLLKEAKKVNA-KTINGLGMLIYQGAVAFKIWTGVEPNIEVMKNAIIDKITK.. 287
10 -90.5003fbt_A mol:protein length:282 chorismate mutase and shikimate 5-dehydrogenase fusion protein  ali model follow..  30  1MSLNTSIYGLIGEKLGHSHSSYIHKLIFEKVGIKGIYNLFEVPKEKLKESVDTFKIIKCGGLNVTIPYKVEVMKELYEISEKARKIGAVNTLKF-SREGISGFNTDYIGFGKMLSKFRVEIKNNICVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEKTSEIYGEFKVIS-------ELSNLKGDVIINCTPKGMYPGESPVDKEVVAKFSSAVDLIYNPVETLFLKYARESGV-KAVNGLYMLVSQAAASEEIWNDISIDEIIVDEIFEVLEEK.. 271
11 -89.8002hk9_A mol:protein length:275 Shikimate dehydrogenase  ali model follow..  31  2INAQTQLYGVIGFPVKHSLSPVFQNALIRYAGLNAVYLAFEINPEELKKAFEGFKALKVKGINVTVPFKEEIIPLLDYVEDTAKEIGAVNTVKF-ENGKAYGYNTDWIGFLKSLKSLIPEVKEKSILVLGAGGASRAVIYALVKEGA-KVFLWNRTKEKAIKLAQKFPLEV---VNSPEEVIDKVQVIVNTTSVGLKDEPEIFNYDLIKKDHVVVDIIYKE--TKLLKKAKEKGA-KLLDGLPMLLWQGIEAFKIWNGCEVPYSVAERSVRDLRG... 269
12 -89.7003tnl_A mol:protein length:315 Shikimate dehydrogenase  ali model follow..  24  27ITGHTELIGLIATPIRHSLSPTMHNEAFAKLGLDYVYLAFEVGDKELKDVVQGFRAMNLRGWNVSMPNKTNIHKYLDKLSPAAELVGAVNTVVN-DDGVLTGHITDGTGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEKTVEKINSEDHEQLRKEIAESVIFTNATGVGMKPETLLPSADMLRPELIVSDVVYKPTKTRLLEIAEEQGC-QTLNGLGMMLWQGAKAFEIWTHKEMPVDYIKEIL........ 308
13 -89.3002nlo_A mol:protein length:302 Shikimate dehydrogenase  ali model follow..  22  13AMNDSILLGLIGQGLDLSRTPAMHEAEGLAQGRATVYRRIDASGQDLKTLLDAALYLGFNGLNITHPYKQAVLPLLDEVSEQATQLGAVNTVVIDATGHTTGHNTDVSGFGRGMEEGLPNAKLDSVVQVGAGGVGNAVAYALVTHGVQKLQVADLDTSRAQALADVINNAVGVDARGIEDVIAAADGVVNATPMGMPAHPTAFDVSCLTKDHWVGDVVYMPIETELLKAARALGC-ETLDGTRMAIHQAVDAFRLFTGLEPDVSRMRETFLS...... 295
14 -89.3003t4e_A mol:protein length:312 Quinate/shikimate dehydrogenase  ali model follow..  29  21VTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPYTYMAFEVDNTTFASAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVN-DDGYLRGYNTDGTGHIRAIKESGFDMRGKTMVLLGAGGAATAIGAQAAIEGIKEIKLFNRKFEKAVAFAKRVNENTDADQHAFTEALASADILTNGTKVGMKPESLIGDVSLLRPELLVTECVYNPHMTKLLQQAQQAGC-KTIDGYGMLLWQGAEQFELWTGKAFPLDYVKQVMGFT..... 305
15 -88.1005dzs_A mol:protein length:276 Shikimate dehydrogenase (NADP(+))  ali model follow..  23  1....MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDISKLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILL-RENMLYGYNTDYFGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNSKAILID-------ELKHIKGDIILNATPVGMYPGISPVSKSIIQNFDILIDLIYNPGETEFLRIGNSMGK-KTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLE.. 267
16 -87.5001wxd_A mol:protein length:263 shikimate 5-dehydrogenase  ali model follow..  30  1....MLRFAVLGHPVAHSLSPAMHAFALESLGLEGSYEAWDTPLEALPGRLKEVRR-AFRGVNLTLPLKEAALAHLDWVSPEAQRIGAVNTVLQ-VEGRLFGFNTDAPGFLEALKAGGIPLKGP-ALVLGAGGAGRAVAFALREAGL-EVWVWNRTPQRALALAEEFGLRA--------EKAREARLLVNATRVGLEDSASPLPAELFPEEGAAVDLVYRPLWTRFLREAKAKGL-KVQTGLPMLAWQGALAFRLWTGLLPDPSGMEEAARRALG... 262
17 -84.7001npy_A mol:protein length:271 Hypothetical shikimate 5-dehydrogenase-like protein HI0607  ali model follow..  25  2INKDTQLMSLSGRP--SNFGTTFHNYLYDKLGLNFIYKAFTT--QDIEHAIKGVRALGIRGCAVSMPFKETCMPFLDEIHPSAQAIESVNTIVN-DNGFLRAYNTDYIAIVKLIEK-YHLNKNAKVIVHGSGGMAKAVVAAFKNSGFEKLKIYARNVKTGQYLAALYGYAY-------SLENQQADILVNVTSIGMKGGKLAFPKAFIDNASVAFDVVAMPVETPFIRYAQARGK-QTISGAAVIVLQAVEQFELYTHQRPSDELIAEAAAFARTK.. 270
18 -84.6003u62_A mol:protein length:253 Shikimate dehydrogenase  ali model follow..  26  2......KFCIIGYPVRHSISPRLYNEYFKRAGMNHSYGMEEIPPESFDTEIRRILE-EYDGFNATIPHKERVMRYVEP-SEDAQRIKAVNCVF-----RGKGYNTDWVGVVKSLEG---VEVKEPVVVVGAGGAARAVIYALLQMGVKDIWVVNRTIERAKALDFPVKI---FSLDQLDEVVKKAKSLFNTTSVGMKGEELPVSDDSLKNLSLVYDVIYFD--TPLVVKARKLGVKHIIKGNLMFYYQAMENLKIWGIYDEEV--FKEVFGEVLK... 253
19 -83.3004k28_A mol:protein length:269 Shikimate dehydrogenase family protein  ali model follow..  23  2IRGSTELVAIVGSPIAQVKSPQNFNTWFNHNNCNLAMLPIDLHEAALDSFADTLRGWNLRGCVVTVPYKQALANRVDGLSERAAALGSINVIRRERDGRLLGDNVDGAGFLGAAHKHGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPLTVSTQFSGLEDFDLVANASPVGMGTRASAALLATLQPDTLVADVVTSPEITPLLNRARQVGC-RIQTGPEMAFAQLG-HLGAFMGVTPL................ 267
20 -82.5004p4g_A mol:protein length:277 Shikimate 5-dehydrogenase AroE (5-dehydroshikimate reductase)  ali model follow..  25  1MSEGPKKAGVLGSPIAHSRSPQLHLAAYRALGLDWTYERIECGAAELPVVVGGFGP-EWVGVSVTMPGKFAALRFADERTARADLVGSANTLVR-TPHGWRADNTDIDGVAGALGA-----AAGHALVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGAFDSGGLADAVAAAEVLVSTIPAEVAAG----YAGTLAAIPVLLDAIYDPWPTPLAAAVGSAGG-RVISGLQMLLHQAFAQVEQFTGLPAPREAMTCALAALDLD.. 271
21 -82.4004foo_A mol:protein length:271 Shikimate dehydrogenase  ali model follow..  31  2...KLKSFGVFGNPIKHSKSPLIHNACFLTFQKELRFLGHYHPLPLESHIKSEFLHLGLSGANVTLPFKERAFQVCDKIKGIALECGAVNTLVL-ENDELVGYNTDALGFYLSLKQ----KNYQNALILGAGGSAKALACELKKQGL-QVSVLNRSSRGLDFFQRLGCDCFM------EPPKSAFDLIINATSASLHNENKEVLKGYFKEGKLAYDLAYGF-LTPFLSLAKELKT-PFQDGKDMLIYKAALSFEKFSASQIPYSKAFEVMRSVFLE.. 265
22 -81.8004xij_A mol:protein length:275 Shikimate 5-dehydrogenase  ali model follow..  27  3MVPDSRKAAVLGSPITHSRSPQLHLAAYRALGLPWTYERIECTAEQLPGLVSALGP-EWVGLSVTMPGKFAALEFADQRTDRAQLVGSANTLVRMPTGGWRADNTDVDGVTGALGT-----AGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARRCGDIGGAALADAVASADAAVSTIPADA----AAVYADALARVPRVLDAIYDPWPTPLAQAVEAAGG-EAINGLQMLLNQAFAQVEQFTGMPAPKEAMRAAL........ 268
23 -81.6004fsh_A mol:protein length:271 Shikimate dehydrogenase  ali model follow..  30  2...KLKSFGVFGNPIKHSKSPLIHNACFKKLGFLGHYRPILLPLES--HIKNEFLHLGLSGANVTLPFKERAFQVCDKIKGIALECASINTLVL-ENDELVGYNTDALGFYLSLKH----QNYQNALILGSGGSAKALACGLKKQGL-KVSVLNRSPRGLDFFQRLGCDCFM------EPPKSAFDLIINATSASLNNELPEVLKGYFKEAKLAYDLAYGF-LTPFLALAKELKI-PFQDGKDMLIYQASLSFEKFSASQIPYSKAFEVMRSVFLE.. 265
24 -73.9002gpt_A mol:protein length:523 3-dehydroquinate dehydratase/ shikimate 5-dehydrogenase  ali model follow..  24  230IGPDTKVYGIIGKPVSHSKSPIVHNQAFKSVDFNGVYVHLLV--DNLVSFLQAYSSSDFAGFSCTIPHKEAALQCCDEVDPLAKSIGAVNTILRKSDGKLLGYNTDCIGSISAIEDGSSPLASKTVVVIGAGGAGKALAYGAKEKGA-KVVIANRTYERALELAEAIGGKALSLTDLDNYHPEDGMVLANTTSMGMQPEETPISKDALKHYALVFDAVYTPRITRLLREAEESGA-ITVSGSEMFVRQAYEQFEIFTGLPAPKELYWQIMSKYGSRE. 518
25 -71.0005swv_C mol:protein length:531 Pentafunctional AROM polypeptide  ali model follow..  25  247GEILPEKFFLFGKPIKHSRSPILHSTAYELLGLPHTYEAFET--DTVDEVQKVLNLPDFGGANVTIPYKLSVMKFMDELSDEARFFGAVNTIIPIDKLVLRGDNTDWRGIYDTFANAGVSLRDTNGLVIGAGGTSRAAIYSLHRLGVSRIYLLNRTLANSYRVQDVFPPDYNIHIIDSDNISVTLSAVVSTIPADIELPEIKALLANKADGGVFLDMAYKPLHTPLMAVASDLEW-KCCNGLEALVRQGLASFHLWTGMTAPFDAVYQKVIE...... 531
26 -35.1004q39_A mol:protein length:260 PYLD, pyrrolysine synthase  ali model follow..  7  10LININMQLQKADSAVQEVTGLDIKGICKALYGTFSSSEKVGIVPGNFSASLHAI--TQYFGFDSFVTDMPDVSGYYEAVQNGAEIILMADDRTFNLKNGKMANNQPGIIYAEIASRY-LKADSKDVLVVGLGKVGFPGAEHLVQKDF-RVYGYDADETLLERATSNLG-----IIPFDPANPKKFSIIFEATPCAN-----TIPEAVLSENCVLSTPGIPCAISEELRDKYEVQLIPLGIGTASMLYSVL............................ 260
27 -16.9003oj0_A mol:protein length:144 Glutamyl-tRNA reductase  ali model follow..  22  2.......................................................................................................NAGKVSIPSIVYDIVRKNGGNKILLVGNGMLASEIAPYFSYPQY-KVTVAGRNIDHVRAFAEKYEYEY-VLINDIDSLIKNNDVIITATSS----KTPIVEERSLMPGKLFIDL............................................................. 109
28 -15.2003ic5_A mol:protein length:118 putative saccharopine dehydrogenase  ali model follow..  17  4.........................................................................................................................MRWNICVVGAGKIGQMIAALLKTSSNYSVTVADHDLAALAVLNRMGVATKQVDAKDLAKALGGFDAVISAAPFFLT---PIIAKAAKAAGAHYFDLTEDVAATNAVRALVEDS............................................ 116
29 -14.8001gpj_A mol:protein length:404 GLUTAMYL-TRNA REDUCTASE  ali model follow..  16  49..NRVEVYASGARDRAEELGDLIHDDAWVKRGSEAVRHLFRVA----------------SGLESMMVGEQEILRQVKKAYDRAARLGTLDEALKINLGKRAREETRGSAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDLGGEA-VRFDELVDHLARSDVVVSATAIHVDDVREALRKRDRRSPILIIDIVRTIDDLRVIARENLERRRKEIPKVEKLIEEELSTVEEELKERRLVADVAKSLHEIKDREL 346
30 -14.6004n7r_A mol:protein length:472 Glutamyl-tRNA reductase 1, chloroplastic  ali model follow..  13  74..NRMEIYVLALSQ--HRGVKEVTEWMSKTSGIPVSEICQHRFLLYNKDATQHIFEVS-AGLDSLVLGEGQILAQVKQVVKVGQGVNGFGRNISGTVGKRVRTETNIASGAVSVSSAAVELVSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRSEERVSAIREEMPGIE-RPLDEMLACASEADVVFTSTASE---ENLPQASPEVGGLRHFVDIVYNVDDLKEVVAANKEDRMRKAMEAQTIITEESTQFEAWLETVPTIKKLRAYAERIRVAEL 390
31 -14.1005l76_A mol:protein length:497 Alpha-aminoadipic semialdehyde synthase, mitochondrial  ali model follow..  15  3..................................................................................SSGVDLGTENLYFQSMAL----PDKYKYIQTLRESRERAQSRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSQEEKLGFLVAKQDLVISLLPYVLH---PLVAKACITNKVNMVTASYTPALKELEKSVEDAGITIIGEGLHMLAMESIDKAK........................ 185
32 -12.4003abi_A mol:protein length:365 Putative uncharacterized protein PH1688  ali model follow..  11  1.................................................................................................................MNHKVIEGRHMKVLILGAGNIGRAIAWDLKDE--FDVYIGDVNNENLEKVKEFATPLK--NFDKLVEVMKEFELVIGALPGFLG---FKSIKAAIKSKVDMVDVSFMPENPLELRDEAEKAQVTIVFDAGILMGRIFQELD........................ 145
33 -12.4002axq_A mol:protein length:467 Saccharopine dehydrogenase  ali model follow..  16  1..............................................................................................................MGSSGHIEGRHMGKNVLLLGSGFVAQPVIDTLAANDDINVTVACRTLANAQALAKPSGSKAI-DDSALDKVLADNDVVISLIPYTFH---PNVVKSAIRTKTDVVTSSYSPALRELEPEIVKAGITVMNEGIHLYAVKTIDEVH........................ 152
34 -11.9001e5l_A mol:protein length:450 SACCHAROPINE REDUCTASE  ali model follow..  17  1........................................................................................................................MATKSVLMLGSGFVTRPTLDVLTDSG-IKVTVACRTLESAKKLSAGVQHSTPISLAALDAEVAKHDLVISLIPYTFH---ATVIKSAIRQKKHVVTTSYSPAMMELDQAAKDAGITVMNEGIHLYAIKTIEEVH........................ 142
35 -10.8004b4u_A mol:protein length:303 BIFUNCTIONAL PROTEIN FOLD  ali model follow..  13  54.........LVGDDGASATYVRMKGNACRRVGMDSLKIELETTTEQLLAEIEKLNAPDVHGILLQHPVPAQIDE--RACFDAISLAKDVDGVTCLGFGRMAMGEATPAGIMTILKENNIEIAGKHAVVVGRSAILGKPMAMMLLQANATVTICHS------------------RTQNLPELVKQADIIVGAV-----GKAELIQKDWIKQGAVVVDAGFHPRDGGGVGDIQLQGIEEIASGVGTLIRQTVEAAEKALG.................... 297
36 -10.5003d4o_A mol:protein length:293 Dipicolinate synthase subunit A  ali model follow..  17  142.............................................................................................................IMMAIQHTDFTIHGANVAVLGLGRVGMSVARKFAALGA-KVKVGARESDLLARIAEM--GMEPFHISKAAQELRDVDVCINTIPALVVTANV---LAEMPSHTFVIDLASKPGGTDFRYAEKRGIKALLVPGLPGIVAPKTAG-----------RILADVLVKLLAEP. 292
37 -10.5003l07_A mol:protein length:285 Bifunctional protein folD  ali model follow..  11  41.........IVGNDPASKTYVASKEKACAQVGIDSQVITLHTTESELLELIDQLNNSSVHAILVQLPLPAHINK--NNVIYSIKPEKDVDGFHPTNVGRLQLRDKKCLGIMTMLREYGIKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHR------------------FTTDLKSHTTKADILIVAV-----GKPNFITADMVKEGAVVIDVGINHVDGKIVGDVDFAAVKDKVAGVGELLYNTFQCAQ........................ 281
38 -10.2004ina_A mol:protein length:405 saccharopine dehydrogenase  ali model follow..  22  2...........................................................................................................................AKVLQIGAGGVGGVVAHKMAMNRFSHITLASRTLSKCQEIAQSIKAKGYVDADSIEELVAKPQIVLNIALPYQD---LTIMEACLRTGVPYLDTFEYKEQWAFHDRYKEKGVMALLGGVNVFCAYAQKHYF........................ 159
39 -9.9702rir_A mol:protein length:300 Dipicolinate synthase, A chain  ali model follow..  10  144.............................................................................................................IMLAIQHTDYTIHGSQVAVLGLGRTGMTIARTFAALGA-NVKVGARSSAHLARITEM--GLVPFHTDELKEHVKDIDICINTIPSMILNQTV---LSSMTPKTLILDLASRP......................................................... 249
40 -9.8301lu9_A mol:protein length:287 Methylene Tetrahydromethanopterin Dehydrogenase  ali model follow..  13  4..............LLFQFDTDATPSVFDDGGADHITGYGNVTPDNVGAYVDGIYTRGGKEKQSTAIF-AAGERVFEAVKKRFFGPFRVSCMLDSNG----SNTTAAAGVALVVKAAGGSVKGKKAVVLAGGPVGMRSAALLAGEGA-EVVLCGRKLDKAQAAADSVNKRFKVNVASRAEAVKGAHFVFTAGAIGLE................................................................................. 201
41 -9.8201dia_A mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLOHYDROLASE  ali model follow..  11  42.........QVGNRDDSNLYINVKLKAAEEIGIKATHIKLTTTESEVMKYITSLNESTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGRLARGDLN-KGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHS------------------KTAHLDEEVNKGDILVVAT-----GQPEMVKGEWIKPGAIVIDCGINYVDVAYDEAKERASFITPVPGVAMLMQSTVESAK........................ 292
42 -9.6805nhs_A mol:protein length:296 Bifunctional protein FolD  ali model follow..  11  49.........LVGGDPASTVYVRNKRRAAEKVGIEAFDYDLGTGEAELLSLIDQLNAPKIHGILVQLPLPGIADA--SRLIHRIDPRKDVDGFHPQNVGHLALREFTPRGIVTLLAHTDQPVRGRNATIVGVSNHVGRPMALELLIAGCTVSCCHKFTPAD----------------VLQTHVRDADILVVAV-----GRPGLIPGDWVKPGAVVIDVGINRLDDGRL-AQRASWITPVPGGVGTLMQNTIEAAD........................ 291
43 -9.6705tc4_A mol:protein length:316 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial  ali model follow..  11  40.........LVGENPASHSYVLNKTRAAAVVGINSETIMKSISEEELLNLINKLNNDNVDGLLVQLPLPEHIDE--RRICNAVSPDKDVDGFHVINVGRMCLDQYS-WGVWEIIKRTGIPTLGKNVVVAGRSKVGMPIAMLLHTDGAHERPGGDATVTISHR---------YTPKEQLKKHTILADIVISAA-----GIPNLITADMIKEGAAVIDVGINRVHDPVTAKPKLVGITPVPGGVGMLMKNTIIAAKKVLRLEEREVLKSKEL........ 311
44 -9.6303c24_A mol:protein length:286 Putative oxidoreductase  ali model follow..  11  1............................................................................................................GMVKDKND----VGPKTVAILGAGGKMGARITRKIHDSAHHLAAIEIAPEGRDRLQGM-----GIPLTDGDGWIDEADVVVLALPDNIIEKVAEDIVPRVRPGTIVLIL............................................................. 100
45 -9.5504cjx_A mol:protein length:319 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC, PUTATIVE  ali model follow..  10  57.........ICGKRKDSQTYVRLKRKAAAACGFRNFSVELNVTQEALEREVIRLNEEACHSIVVQLPLPPHIDK--VAALSKIKPEKDADCLLPVNVGQLHIRERN-SAVMELLRCSGVEICGKRVVVLGRGDIAGLPVATLLANEDATVTVVHSATPLC----------------DIADIVRASDIVVSAA-----GQPGLVRGEWIKLGAAVIDVGTTPVDVCFDVARKRAAYITPVPGVSMLLKNTLTMFK........................ 307
46 -9.5505o22_A mol:protein length:289 Bifunctional protein FolD  ali model follow..  12  41.........LVGSNPASQIYVASKRKACEEVGFVSRSYDLTTSEAELLELIDTLNANTIDGILVQLPLPAGIDN--VKVLERIHPDKDVDGFHPYNVGRLCQRAPTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHR------------------FTKNLRHHVENADLLIVAV-----GKPGFIPGDWIKEGAIVIDVGINRLENGKV-AKRASYITPVPGGVGTLIENTLQACVEYHDPQDE................ 289
47 -9.5503p2o_A mol:protein length:285 Bifunctional protein folD  ali model follow..  12  40.........LVGDNPASQTYVKSKAKACEECGIKSLVYHLNITQNELLALINTLNHDSVHGILVQLPLPDHICK--DLILESIISSKDVDGFHPINVGYLNLGLESGFGVMKLLKAYEIDLEGKDAVIIGASNIVGRPMATMLLNAGATVSVCHI------------------KTKDLSLYTRQADLIIVAA-----GCVNLLRSDMVKEGVIVVDVGINRLESGKI-SKKSSYITPVPGGVGMLLENTVKSAKNRLN.................... 285
48 -9.5304rl6_A mol:protein length:427 Saccharopine dehydrogenase  ali model follow..  15  2...........................................................................................................................SRLLVIGCGGVAQVAISKICQDSFTEIMIASRTKSKCDDLKAKLEGKTSLDADKVEEVIAKPEAVLNVALPYQD---LTIMDACLATGVHYIDTFDYSWQWAYQEKFKEAGLTALLGGVSVFSAYALKHYF........................ 178
49 -9.5202i99_A mol:protein length:312 Mu-crystallin homolog  ali model follow..  15  88.................................................................VPSHQATVLLFEPSNGTLLAVMDGNVITAKRTAAVSAIATKFLK----------PPSSEVLCILGAGVQAYSHYEIFTEFSFKEVRIWNRTKENAEKFADTVQGEVRV-CSSVQEAVAGADVIITVTLAASRPDWRELDDELMKEAVLYVD.............................................................. 248
50 -9.4602ph5_A mol:protein length:480 Homospermidine synthase  ali model follow..  9  13..........................................................................................................................KNRFVILGFGCVGQALMPLIFEKKPSQVTIIAAEGTKVDVAQQYGVSFKLQQITPIGSTLEENDFLIDVSIGISS---LALIILCNQKGALYINAATEPWKEEVLRLKDKTQKTALITGLSHFIKEALLNIA........................ 175
51 -9.4301vll_A mol:protein length:334 alanine dehydrogenase  ali model follow..  12  84.................................................................LPTVMALMILNSPETGFPLAVMDATYTTSLRTGAAGGIAAKYLA----------RKNSSVFGFIGCGTQAYFQLEALRRFDIGEVKAYDVREKAAKKFVSYCEDRGISASVQPAEEASRCDVLVTTTPSADGPGKQELDVEILKKAKIVVDDLEQAKHGGEINVAVSKGVEDVHATIGEVI................................ 278
52 -9.4203dtt_A mol:protein length:245 NADP oxidoreductase  ali model follow..  16  1..............................................................................................................MGSDKIENLYFQGMKIAVLGTGTVGRTMAGALADLG-HEVTIGTRDPKATLARAEPDAMGAPVHLAAFADVAAGAELVVNATEGASSIAALTAAGAENLAGKILVDIA............................................................ 118
53 -9.3706ape_A mol:protein length:298 Bifunctional protein FolD  ali model follow..  13  45.........LVGKDPASITYVNMKIKACERVGMDFDLKTLNVTEAELLSLIKDYNTQNISGVLVQLPLPRHIDS--KMVLEAIDPSKDVDGFHPLNIGKLCTQKETPMGVMRLLKHYHIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHI------------------LTKDISFYTQNADIVCVGV-----GKPDLIKASMLKKGAVVVDIGINHLNDGRI-QKVAGFITPVPKGVGSLLENTLIAFE........................ 285
54 -9.3704bv8_A mol:protein length:335 THIOMORPHOLINE-CARBOXYLATE DEHYDROGENASE  ali model follow..  16  104.................................................................VPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIATKLLK----------PPGSDVLCILGAGVQAYSHYEIFTEFSFKEVRMWNRTRENAEKFASTVQGDVRV-CSSVQEAVTGADVIITVTMAASRPDWRELDDELMRQAVLYVD.............................................................. 264
55 -9.3504a26_A mol:protein length:300 PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC  ali model follow..  11  44.........IVGQRMDSKKYVQLKHKAAAEVGMASFNVELDISQEVLEVNVEKLNNPNCHGIIVQLPLPKHLNE--NRAIEKIHPHKDADALLPVNVGLLHYKGRE-KGVIVLLKRCGIEMAGKRAVVLGRSNIVGAPVAALLMKENATVTIVHSGTSTE----------------DMIDYLRTADIVIAAM-----GQPGYVKGEWIKEGAAVVDVGTTPVDVCFEEAAARAAWISPVPGIAMLLENTLEAFKAALGVS.................. 300
56 -9.3505n2i_A mol:protein length:232 Reduced coenzyme F420:NADP oxidoreductase  ali model follow..  14  16.......................................................................................................................DVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGMDNAGAAEAGDVVIVAVPWDGHRALLESLKDVLAGKIVV................................................................ 110
57 -9.3304a5o_A mol:protein length:286 BIFUNCTIONAL PROTEIN FOLD  ali model follow..  11  42.........LVGTDPASQVYVAHKRKDCEEVGFLSQAYDLETSQDDLLALIDRLNDPAIDGILVQLPLPAHLDA--SLLLERIHPDKDVDGFHPYNIGRLAQRMPTPKGIMTLLASTGADLYGMDAVVVGASNIVGRPMALELLLGGCTVTVTHR------------------FTRDLADHVSRADLVVVAA-----GKPGLVKGEWIKEGAIVIDVGINRQADGRL-AQRASWITPVPGGVGCLLENTLHAAE........................ 282
58 -9.2902hae_A mol:protein length:386 Malate oxidoreductase  ali model follow..  13  130..................................................LEDIGAPKCFRILQRLSEEMNIPVFHDDQQGTAVVVSA--------------------AFLNALKLTEKKIEEVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDETCLNEYHLEIARITNPERLSGDLETALEGADFFIGVSRGNILKPEW---IKKMSRKPVIFALA-NPVPEIDPELAREAGAFIVATGRSDHPNQVNNLL-IMKGAVEKRSKITKNMLLSAVEAI 346
59 -9.2605gzi_B mol:protein length:359 Lysine cyclodeaminase  ali model follow..  16  95.................................................................LPTILGTVARYDDTTGALTALMDGVLLTALRTGAASAVASRLLA----------RPDSHTLGLIGTGAQAVTQLHALSLLPLQRALVWDTDPAHRESFARRAAFTGSVEIAEPARIAAEADVISTATSVAVGQG-PVLPDTGVREHLHINAVGADLVGKTELPLGLLERAFVTADHPEQALREG............................. 269
60 -9.2105yeq_A mol:protein length:340 Ketol-acid reductoisomerase (NADP(+))  ali model follow..  20  15........................................................................................................................IKEKRVAVLGYGSQGRAWALNLRDSGI-KVSVGLEREGNSWKQAEN----DGFKPLRTEEAVRNSDIIIFLLP..................................................................................... 82
61 -9.1404pwy_A mol:protein length:264 Calmodulin-lysine N-methyltransferase  ali model follow..  11  75.............................................................................................................LAYYCLKHNNIFRALAVCELGGGMTCLAGLMVAISADVKEVLLTDGNEKAIRNVQDIITRNQKAGVFKTQK--------ISSCFLRWDNETDVSQLEGHFDIVMCADCLFLDQYRASL-----------VDAIKRLLQPRGKAMVFAPRRGNTLNQFCNLAEKA..... 219
62 -9.1001vl6_A mol:protein length:388 malate oxidoreductase  ali model follow..  13  145.............................................................ILQRLSEEMNIPVFHDDQQGTAVVVSA--------------------AFLNALKLTEKKIEEVKVVVNGIGAAGYNIVKFLLDLGVKNVVAVDETCLNEYHLEIARITNPERLSGDLETALEGADFFIGVSRGNILKPEW---IKKMSRKPVIFALA-NPVPEIDPELAREAGAFIVATGRSDHPNQVNNLL-IMKGAVEKRSKITKNMLLSAVEAI 350
63 -9.1002qq5_A mol:protein length:260 Dehydrogenase/reductase SDR family member 1  ali model follow..  14  2.......................................................................................................................PMNGQVCVVTGASGIGRGIALQLCKAGA-TVYITGRHLDTLRVVAQEAQSLGSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLIVVISSPG-VPYGVGKAACDKLAADCAHELRR.. 181
64 -9.0802c2x_A mol:protein length:281 METHYLENETETRAHYDROFOLATE DEHYDROGENASE-METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE  ali model follow..  14  39.........LVGDDPGSQAYVRGKHADCAKVGITSIRRDLDISTATLNETIDELNAPDCTGYIVQLPLPKHLDE--NAALERVDPAKDADGLHPTNLGRLVLGTPTPRGIVHLLRRYDISIAGAHVVVIGRGVTVGRPLGLLLTRRSENATVT----------------LCHTGTRDLPALTRQADIVVAAV-----GVAHLLTADMVRPGAAVIDVGVSRTDDGLVGDVLAGHVSPNPGGVGFLLTNVVELAE........................ 279
65 -9.0501np3_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  22  14........................................................................................................................IQGKKVAIIGYGSQGHAHACNLKDSGV-DVTVGLRSGSATVAKAEA----HGLKVADVKTAVAAADVVMILTP..................................................................................... 81
66 -9.0404m54_A mol:protein length:339 Putative ornithine cyclodeaminase  ali model follow..  9  95.................................................................MERASGVIILNDPETNYPIAVMEASLISSMRTAAVSVIAAKHLA----------KKGFKDLTIIGCGLIGDKQLQSMLEQHIERVFVYDQFSEACARFVDRWQQQRPIATENAKEAVSNGEVVITCTV----TDQPYIEYDWLQKGAFISNISIMDVHKEVFIKADK-----VVDDWSQCNREKKTINQLVLEGKFSKEALHAELGQLVTGDI 295
67 -9.0405g6r_A mol:protein length:295 IMINE REDUCTASE  ali model follow..  19  2..........................................................................................................................SKHIGIFGLGAMGTALAAKYLEHG--KTSVWNRTTAKAIPLVEQ----GAKLASTISEGVNANDLIIICLLNNQVVEDALRDALQTLPSKTIVNLT-TPNQARKLADFVTSHGARYIHGGIMAVPTMIGS--LYSGESLELFQSIESHLSLLGMSK 156
68 -9.0105t57_A mol:protein length:296 Semialdehyde dehydrogenase NAD-binding protein  ali model follow..  17  17...........................................................................................................................EKIALFGAGGKGVRLAKNLLKSDY-RVSHVEVSEVGKKRLKDELG----LECVSTEAALDNVDVVILAVPDTIIGKIAAQIAPQLRPGTMVMTL............................................................. 106
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Harder T, Kolodny R, Sitbon E, Li Z, Godzik A. Using an alignment of fragment strings for comparing protein structures. Bioinformatics. 2007 Jan 15;23(2):e219-24.