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Query: [K] COG1709 Predicted transcriptional regulator, from VFDB

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVNINMFEKEKEILAKRIAGEIVLSPDPGKTMRKWREIFGISQTELADYLGVSSSVISDYEGGRRKSPGASTIRKFVEALIEIDEKRGGNVIKAFSRTFSSEIPTSAILDIREFDIPVTVKDIVDAVKGEIVANPDLIDRKIYGYTVVDSIQAILEMSAEEFLKLYGWTTERALVFTKVTTGRSPMIAVRVQGLKPAMVVLHGVKRLDELAVKIAEKERVPLVVSKAENETELITGLRRLVTSILast
1 -36.5002p5t_A mol:protein length:158 Putative transcriptional regulator PezA  ali model follow..  16  2...........................IGKNIKSLRKTHDLTQLEFARIVGISRNSLSRYENGTSS-VSTELIDIICQKFVSYVDIVGEDKMLNPVEDYELTLKIEIVKE...................................................................................................................................... 84
2 -34.1003op9_A mol:protein length:114 Pli0006 protein  ali model follow..  14  1..................SNAMTIQHQFAENLSRLKKEHGLKNHQIAELLNVQTRTVAYYMSGETK-PDIEKLIRLATYFLSIDELVGYVQEDKVWNDLSLKQWLLSLNLRSE................................................................................................................................... 95
3 -31.5001b0n_A mol:protein length:111 PROTEIN (SINR PROTEIN)  ali model follow..  18  2...........................IGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQTNPSIQFLEKVSAVLVSVHTLLDEKHETEYDGQLDSEWEKLVRDAMTSGVSKKQFREFLDYQK.................................................................................................................... 103
4 -30.8003mlf_A mol:protein length:111 transcriptional regulator  ali model follow..  25  10...................ENLYFQSNAMKTLKELRTDYGLTQKELGDLFKVSSRTIQNMEKDSTN-IKDSLLSKYMSAFVKYDDIFLGNEYEN...................................................................................................................................................... 84
5 -29.4002l49_A mol:protein length:99 C protein  ali model follow..  21  1.......................MSNTISEKIVLMRKSEYLSRQQLADLTGVPYGTLSYYESGRST-PPTDVMMNILQTPFTKYTLWFMTNQIA...................................................................................................................................................... 71
6 -28.2003kxa_A mol:protein length:141 Putative uncharacterized protein  ali model follow..  24  37VRKNPRRKAAMDRAAARIA-DKIALKAGGETFVSLRMKKGFTQSELATAAGLPQPYLSRIENSKQS-LQDKTVQKLANALVSPLEVR............................................................................................................................................................. 122
7 -27.6005k98_B mol:protein length:91 Antitoxin HipB  ali model follow..  20  9....................KIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDN-TTLTTFFKILQSLLSMTLCDTKNASPESTEQQDLE.............................................................................................................................................. 90
8 -27.5002wiu_B mol:protein length:88 HTH-TYPE TRANSCRIPTIONAL REGULATOR HIPB  ali model follow..  20  6....................KIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISNFENNPDN-TTLTTFFKILQSLLSMTLCDAKNASPESTEQQNLE.............................................................................................................................................. 87
9 -27.5004o8b_A mol:protein length:122 Uncharacterized protein  ali model follow..  21  2...........................LGTRLKAARIRAGYSQKQLGMLVGMDSARMNQYERERHS-PNMRTSEQLAMVLVPMAYLYCPED......................................................................................................................................................... 69
10 -27.3003f51_A mol:protein length:117 Clp gene regulator (ClgR)  ali model follow..  26  2VTYTTLLDKPISESAPRKAPEPLLREALGAALRSFRADKGVTLRELAEASRVSPGYLSELERGRKE-VSSELLASVCHAL.................................................................................................................................................................... 80
11 -26.7002kpj_A mol:protein length:94 SOS-response transcriptional repressor, LexA  ali model follow..  12  6.......................QKAIFSENLNSYIAKSEKTQLEIAKSIGVSPQTFNTWCKG-IAIPRMGKVQALADYFINKSDLIEDKKLNI...................................................................................................................................................... 76
12 -26.6005woq_A mol:protein length:120 Transcriptional regulator ClgR  ali model follow..  25  1.................MAMTALLREVIGDVLRNARTDQGRTLREVSDAARVSLGYLSEVERGRKE-ASSELLSAICDAL.................................................................................................................................................................... 62
13 -26.5001x57_A mol:protein length:91 Endothelial differentiation-related factor 1  ali model follow..  28  10.......................VTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESG-RAIPNNQVLGKIERAILKLRGKDIGKPIEK...................................................................................................................................................... 80
14 -26.4005jub_A mol:protein length:310 Transcriptional regulator  ali model follow..  14  1.....................MNLKDSIGLRIKTERERQQMSREVLCLGAELTVRQLIRIEKG-ESLPSLDRLSYIAKRLKSMTELLDQDNITIPDEYYEMKNRLIKFPTYRNPDRIKSKLTLIEEV..................................................................................................................... 107
15 -26.2003lfp_A mol:protein length:98 Csp231I C protein  ali model follow..  20  2...........................LIRRLKDARLRAGISQEKLGVLAGIDEASMNQYEKGKHA-PDFEMANRLAKVLIPVSYLYTPED......................................................................................................................................................... 69
16 -25.9003ivp_A mol:protein length:126 Putative transposon-related DNA-binding protein  ali model follow..  14  11.........................RALGLAIKEARKKQGLTREQVGAMIEIDPRYLTNIENKGQH-PSLQVLYDLVSLLVSVDEFF............................................................................................................................................................. 72
17 -25.8005a7l_A mol:protein length:80 CI  ali model follow..  16  1.......................MQTDTSNRLKQIMAERNLKQVDILNLIKLSKSTLSQYVNSVQS-PDQNRIYLLAKTLVSEAWLMGFDV......................................................................................................................................................... 77
18 -25.8005uk3_A mol:protein length:176 Uncharacterized protein  ali model follow..  13  1MRIYSRLFQISSANYAR--------QIMSNQFIKAKESKGLTYQQMAQLLSVNKVWLTSVLHGQNC-CDIQLAHRICDTLISHEYANELTS......................................................................................................................................................... 83
19 -25.8002mez_A mol:protein length:106 Multiprotein Bridging Factor (MBP-like)  ali model follow..  30  4....................ELEIVTDYYKIIKTAREQLGISQQQLAQKLKVSENIVKRFESG-KLKPTISQARQLEKILIKLVTPLENNE......................................................................................................................................................... 74
20 -25.8001adr_A mol:protein length:76 P22 C2 REPRESSOR  ali model follow..  24  3........................TQLMGERIRARRKKLKIRQAALGKMVGVSNVAISQWERS-ETEPNGENLLALSKALCSPDYLLKGDLSQT...................................................................................................................................................... 72
21 -25.5004pu3_D mol:protein length:118 Toxin-antitoxin system antidote transcriptional repressor Xre family  ali model follow..  19  24.......KVYEDTLLETIMASPLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGED--VYISTVFKILDGL.................................................................................................................................................................... 94
22 -25.5002ofy_A mol:protein length:86 Putative XRE-family transcriptional regulator  ali model follow..  24  10....................ELERGQRLGELLRSAR--GDMSMVTVAFDAGISVETLRKIETGRIATPAFFTIAAVARVLLSLDDVA............................................................................................................................................................. 75
23 -25.4001dw9_A mol:protein length:156 CYANATE LYASE  ali model follow..  16  1MIQSQINRNIRL--------------DLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQA-LPADAARLVGAKLLDEDSILL............................................................................................................................................................ 74
24 -25.3001per_L mol:protein length:69 PROTEIN (434 REPRESSOR)  ali model follow..  20  1..........................SISSRVKSKRIQLGLNQAELAQKVGTTQQSIEQLENGKT--KRPRFLPELASALVSVDWLLNGTSDSNVR.................................................................................................................................................... 69
25 -25.1003zhi_A mol:protein length:83 CI  ali model follow..  16  1......................MLKTDTSNRLKQIMAERNLKQVDILNLIKLSKSTLSAYVASVQS-PDQNRIYLLAKTLVSEAWLMGRS.......................................................................................................................................................... 77
26 -25.0002qfc_A mol:protein length:293 PlcR protein  ali model follow..  16  1......................MQAEKLGSEIKKIRVLRGLTQKQLSENI-CHQSEVSRIESG-AVYPSMDILQGIAAKLIPIIHFYEVLIYSDIERKKQFKDQVIMLCKQKRYKE................................................................................................................................ 93
27 -25.0003vk0_A mol:protein length:114 Transcriptional regulator  ali model follow..  31  10...............AELPDEQDLRAVLAYNMRLFRVNKGWSQEELARQCGLDRTYVSAVERKRWN-IALSNIEKMAAAL.................................................................................................................................................................... 73
28 -24.9001y9q_A mol:protein length:192 transcriptional regulator, HTH_3 family  ali model follow..  22  3..................LTDVMFKSQIANQLKNLRKSRGLSLDATAQLTGVSKAMLGQIERG-ESSPTIATLWKIASGL.................................................................................................................................................................... 63
29 -24.8005j2y_A mol:protein length:80 Regulatory protein  ali model follow..  17  9........................PQNMAFRAKATRTARRESQETFWSRFGISQSCGSRFENGENLPFPIYLLLHFYIEGITDRQLAD............................................................................................................................................................ 73
30 -24.7003qq6_A mol:protein length:78 HTH-type transcriptional regulator sinR  ali model follow..  22  2........................SSMIGQRIKQYRKEKGYSLSELAEKAGVAKSYLSSIERNLQTNPSIQFLEKVSAVLVSVHTLLDEKHETE...................................................................................................................................................... 72
31 -24.7004z5h_A mol:protein length:72 Antitoxin HipB  ali model follow..  25  4....................KIYSPTQLANAMKLVRQQNGWTQAELAKKIGIKQATISNFENNPDN-TTLTTFFKILQSL.................................................................................................................................................................... 62
32 -24.6003bs3_A mol:protein length:76 Putative DNA-binding protein  ali model follow..  16  8........................QQMMLNRIKVVLAEKQRTNRWLAEQMGKSENTISRWCSNKSQ-PSLDMLVKVAELLVDPRQLINGKI......................................................................................................................................................... 74
33 -24.6003zhm_A mol:protein length:79 CI  ali model follow..  15  1........................KTDTSNRLKQIMAERNLKQVDILNLIKLSKSTLSQYVNSVQS-PDQNRIYLLAKTLVSEAWLMGRS.......................................................................................................................................................... 75
34 -24.4005fd4_A mol:protein length:324 ComR  ali model follow..  17  1...MGSSSSGLVPRGSHMEVWFMNDKEFGQRVRQLRESASMTREQFCDELELSVRQLTRIEAGASK-PTFSKIQYIATRLMGLYELM............................................................................................................................................................. 85
35 -24.4002r63_A mol:protein length:63 REPRESSOR PROTEIN FROM BACTERIOPHAGE 434  ali model follow..  20  1..........................SISSRVKSKMIQLGLNQAELAQKVGTTQQSIEQLENGKT--KRPRFLPELASALVSVDWLLNGT.......................................................................................................................................................... 63
36 -24.2004y42_A mol:protein length:156 Cyanate hydratase  ali model follow..  13  11........................RETLTDTIMMAKIRKNLTFEAINQGTGLSLAFVTAALLGQHP-LPEQAARVVAEKLLDEDAIRLLQTIPLRGSIPGGVPTDPTIYRFYE................................................................................................................................... 99
37 -24.1003omt_A mol:protein length:73 uncharacterized protein  ali model follow..  13  1...................SNAMTERKIFNRLKSVLAEKGKTNLWLTETLDKNKTTVSKWCTNDVQ-PSLETLFDIAEALVDVRELIVSTK......................................................................................................................................................... 72
38 -24.0001utx_A mol:protein length:66 CYLR2  ali model follow..  25  2...........................IINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYN-PSLQLALKIAYYLTPLEDIFQWQP......................................................................................................................................................... 65
39 -24.0002xiu_A mol:protein length:66 CYLR2  ali model follow..  25  2...........................IINNLKLIREKKKISQSELAALLEVSRQTINGIEKNKYN-PSLQLALKIAYYLCPLEDIFQWQP......................................................................................................................................................... 65
40 -24.0003fya_A mol:protein length:99 Regulatory protein  ali model follow..  21  19.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDATYISGIERNSRN-LTIKSLELIMKGL.................................................................................................................................................................... 74
41 -23.8003g5g_A mol:protein length:99 Regulatory protein  ali model follow..  21  19.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTYISGIERNSRN-LTIKSLELIMKGL.................................................................................................................................................................... 74
42 -23.6002k9q_A mol:protein length:77 uncharacterized protein  ali model follow..  10  2..........................ELSNELKVERIRLSLTAKSVAEEMGISRQQLCNIEQS-ETAPVVVKYIAFLRSKVDLNALFDRIIVNKLE.................................................................................................................................................... 71
43 -23.6002jvl_A mol:protein length:107 TrMBF1  ali model follow..  20  31.......................VGKEVGKAIEQGRQEPTMTQAELGKEIGETAATVASYERG-TATPDQNILSKMERVLVKLRGAN............................................................................................................................................................. 96
44 -23.5001zug_A mol:protein length:71 PHAGE 434 CRO PROTEIN  ali model follow..  23  1........................MQTLSERLKKRRIALKMTQTELATKAGVKQQSIQLIEAGVT--KRPRFLFEIAMALCDPVWLQYGT.......................................................................................................................................................... 65
45 -23.3001zz6_A mol:protein length:198 Hydroxypropylphosphonic Acid Epoxidase  ali model follow..  14  1.................MSNTKTASTGFAELLKDRREQVKMDHAALASLLGETPETVAAWENGEGGELTLTQLGRIAHVLTSIGALTPPAGNDL...................................................................................................................................................... 78
46 -23.2005y69_A mol:protein length:151 chain A  ali model follow..  12  1...................GSM-----TIKLLDEFLKKHDLTRYQLSKLTGISQNTLKDQNEKPLNKYTVSILRSLSMISLSVSDVL............................................................................................................................................................. 64
47 -23.1001sq8_A mol:protein length:64 dh434  ali model follow..  26  2..........................LMGERIRARRIQLGLNQAELAQKVGVDQQAIEQLENGKA--KRPRFLPELARALVAVDWLLNGA.......................................................................................................................................................... 64
48 -23.1002b5a_A mol:protein length:77 C.BclI  ali model follow..  37  1.................MINEIEIKRKFGRTLKKIRTQKGVSQEELADLAGLHRTYISEVERGDRN-ISLINIHKICAAL.................................................................................................................................................................... 62
49 -22.8004ghj_A mol:protein length:101 Probable transcriptional regulator  ali model follow..  16  1MSDLGTENLYFQSNAMKHVTAAALAEEIGDRLKQARLNRDLTQSEVAEIAGIARKTVLNAEKGKVQLDIMIAILMALDLTEQIDLFI............................................................................................................................................................. 90
50 -22.8002ef8_A mol:protein length:84 Putative transcription factor  ali model follow..  31  9.........................RCLVQLLTKLRKEASLSQSELAIFLGLSQSDISKIESFERR-LDALELFELLEVV.................................................................................................................................................................... 62
51 -22.6004ia8_A mol:protein length:82 Regulatory protein  ali model follow..  21  8.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTAISGIERNSRN-LTIKSLELIMKGL.................................................................................................................................................................... 63
52 -22.5004i6t_A mol:protein length:82 Regulatory protein  ali model follow..  21  8.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRAYISGIERNSRN-LTIKSLELIMKGL.................................................................................................................................................................... 63
53 -22.5001rio_A mol:protein length:98 Repressor protein CI  ali model follow..  18  12....................QLEDARRLKAIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINA-LNAYNAALLAKIL.................................................................................................................................................................... 70
54 -22.4003eus_A mol:protein length:86 DNA-binding protein  ali model follow..  22  13.........................VYLCQRLRQARLDAGLTQADLAERLDKPQSFVAKVETRERR-LDVIEFAKWMAACEGLD................................................................................................................................................................ 70
55 -22.4004f8d_A mol:protein length:82 Regulatory protein  ali model follow..  19  8.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTYISGIERNSAN-LTIKSLELIMKGL.................................................................................................................................................................... 63
56 -22.4001s4k_A mol:protein length:120 putative cytoplasmic protein ydil  ali model follow..  16  5............................ALELQALRRIFDMTIEECTIYITNNSATWQRWEAGDIPISP-EIIARLKEMKARRQRRI............................................................................................................................................................. 64
57 -22.4004fn3_A mol:protein length:82 Regulatory protein  ali model follow..  21  8.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTYISGIERNSRN-LTIKALELIMKGL.................................................................................................................................................................... 63
58 -22.3004i6u_A mol:protein length:82 Regulatory protein  ali model follow..  21  8.......................LLSKVSFVIKKIRLEKGMTQEDLAYKSNLDRTFISGIERNSRN-LTIKSLELIMKGL.................................................................................................................................................................... 63
59 -22.1001y7y_A mol:protein length:74 C.AhdI  ali model follow..  26  2...............QSHHDHYADLVKFGQRLRELRTAKGLSQETLAFLSGLDRSYVGGVERGQR-NVSLVNILKLATAL.................................................................................................................................................................... 65
60 -22.0003b7h_A mol:protein length:78 Prophage Lp1 protein 11  ali model follow..  17  4.......................DGEFVSEHLMELITQQNLTINRVATLAGLNQSTVNAMFEGRSKRPTITTIRKVCGTLISVHDFFDFPPYNEVEK................................................................................................................................................... 78
61 -21.6002ewt_A mol:protein length:71 putative DNA-binding protein  ali model follow..  17  5.......................YAKQLGAKLRAIRTQQGLSLHGVEEKSQWKAVVVGSYERGDRA-VTVQRLAELADFYVPVQELL............................................................................................................................................................. 70
62 -21.1003kz3_A mol:protein length:80 Repressor protein CI  ali model follow..  16  6....................QLEDARRLKAIWEKKKNELGLSYESVADKMGMGQSAVAALFNGINA-LNAYNAALLAKIL.................................................................................................................................................................... 64
63 -21.1001lli_A mol:protein length:92 PROTEIN (LAMBDA REPRESSOR)  ali model follow..  23  11....................QLEDARRLKAIYEKKKNELGLSQESLADKLGMGQSGIGALFNGINA-LNAYNAALLAKIL.................................................................................................................................................................... 69
64 -20.9003f6w_A mol:protein length:83 XRE-family like protein  ali model follow..  25  13.........................QALLDLLLEARSAAGITQKELAARLGRPQSFVSKTENAERR-LDVIEFMDFCRGI.................................................................................................................................................................... 66
65 -20.4003rzz_A mol:protein length:446 Hydroxyethylphoshphonate Dioxygenase (PhpD)  ali model follow..  14  4........................MRIDPFKLAHWMNARKYTAAQTADLAGLPLDDLRRLLGDEANEPDPAAATALAEALVEPSQLAADAHRNL...................................................................................................................................................... 74
66 -20.0004yv6_A mol:protein length:284 Transcriptional regulator  ali model follow..  33  1.......................MDKELGKTLRRLRQGKQVSISSLADEH-LSKSQISRFERGESE-ISCSRLLNLLDKLITIDEFV............................................................................................................................................................. 63
67 -19.6006b9r_A mol:protein length:450 Hydroxyethylphosphonate dioxygenase  ali model follow..  18  235........................PGDHGAMLRSVMAARLTTVTELADRSGLKTDRVAALCRTPAR-AEWPELSALAEALVSVRELLVPHTTTE...................................................................................................................................................... 304
68 -19.4004ndw_A mol:protein length:153 Nucleoid-associated protein EspR  ali model follow..  12  1MGSSSSGLVP--------RGSHMMSTTFAARLNRLPGRGPHTSAEVIAALTMSAPYLSQLRSGNRTNPSGATMAALANFFIKAAYFTDDEYYEKLDKELQ................................................................................................................................................ 104
69 -19.1003r1f_A mol:protein length:135 ESX-1 secretion-associated regulator EspR  ali model follow..  13  5........................STTFAARLNRLFDRGPHTSAEVIAALTMSAPYLSQLRSGNRTNPSGATMAALANFFIKAAYFTDDEYYEKLDKELQ................................................................................................................................................ 92
70 -19.1003qf3_A mol:protein length:133 ESX-1 secretion-associated regulator EspR  ali model follow..  13  3........................STTFAARLNRLFDRGPHTSAEVIAALTMSAPYLSQLRSGNRTNPSGATMAALANFFIKAAYFTDDEYYEKLDKELQ................................................................................................................................................ 90
71 -18.9002mqk_A mol:protein length:65 ATP-dependent target DNA activator B  ali model follow..  15  5........................ISDIRAGLRTLVENEETTFKQIALESGLSTGTISSFINDKYNGDNERVSQTLQRWLEKYH................................................................................................................................................................ 64
72 -18.9004ryk_A mol:protein length:306 Lmo0325 protein  ali model follow..  20  1........................MGSYGELIREIRLSKGLTQKEVYTGI-ISRSYAIGFEKGKHE-ITLSLFEEILKRIVPLDEFF............................................................................................................................................................. 62
73 -18.6006b9s_A mol:protein length:457 Methylphosphonate synthase  ali model follow..  8  220....ELSSLSLDCGSQYALDFTNHENASLSLLEYYFELSNLTKEKFAKRTNFSMETLADFFTK-KKLPTFDELKIIAKALVNSRDLMPNDLTES...................................................................................................................................................... 309
74 -18.4002o38_A mol:protein length:120 Hypothetical protein  ali model follow..  15  3MVRKSIDRSTAAEITRGIGNERQTKLRLAYALNAVIDRARLSQAAAAARLGINQPKVSALRNYKLEGFSVERLMTLLNAL.................................................................................................................................................................... 93
75 -18.2003bdn_A mol:protein length:236 Lambda Repressor  ali model follow..  18  1.......STKKKPLTQE---QLEDARRLKAIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINA-LNAYNAALLAKIL.................................................................................................................................................................... 69
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Damiano JS, Stehlik C, Pio F, Godzik A., Reed JC. CLAN, a novel human CED-4-like gene. Genomics. 2001 Jul;75(1-3):77-83.