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Query: [S] COG5291 Predicted membrane protein, from VFDB

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPSIPQMNNTFLLGQMLRVPPITRYMTLLISAVALLVYVDAVSPYSLYYSPLFLKRLEIWRVFTSFLYFGKPTLDMFMHVVFLYRYSRMLEEGCVNTSEYFWLILVISSVLFAISNIYGISALGTSFSATITYIWTKRNPRAIVQIFGFISFPAFYLPFILPGFMLLSRRSISIDDVLGIVVGHLFHYFKDVYPRWGRDILSTPCWVKKLFNEHPSSCCKARKGITIREGRERHERNMGYSNASTTSGDSMASLTDMADTKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNESECSLast
1 -19.8004qnz_A mol:protein length:200 Rhomboid protease GlpG  ali model follow..  13  1............AALRERAGPVTWVMMIACVVVFIAMQIDQEVMLWLAWPFDPTLKFEFWRYFTHALMHISL-MHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLS-LMGYVWLRGERDPQSGIYLQRGL-IIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFV............................................................................................................................................................... 181
2 -19.8002nr9_A mol:protein length:196 Protein glpG homolog  ali model follow..  12  1...........MENFLAQQGKITLILTALCVLIYIAQQLGFEDDIMYLYPAYEEQDSEVWRYISHTLVHLSN-LHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLS-VLGYVFIRDKLNHHLFDLPEGFFTMLLVGI-ALGFISPLFGVEMGNAAHISGLIVGLIWGFIDSKLRKNSLELVP.................................................................................................................................................. 195
3 -19.2004njn_A mol:protein length:211 Rhomboid protease GlpG  ali model follow..  13  5.SSGLVPRGSHMAALRERAGPVTWVMMIACVVVFIAMQIDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSL-MHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLS-LMGYVWLRGERDPQSGIYLQRGL-IIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFV............................................................................................................................................................... 196
4 -14.2005cwd_A mol:protein length:179 Designed helical repeat protein  ali model follow..  8  34...................................................................................................................................................................................................................CLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPTKEAARSFCEAAKRAAKESNDEEVEKIAKKACKEVAKQAGMP 170
5 -13.1004dt5_A mol:protein length:143 Antifreeze protein  ali model follow..  8  1...................................................................................................................................................................................................................GYSCRAVGVDGRAVTDIQGTCHAKATGAGAMASGTSEPGSTSTATATGRGATARSTSTGRGTATTTATGTASATSNAIGQGTATTTATGSAGGRATGSATTSSSASQPTQTQTITGPGFQTAKSFARNTATTTVTAS 137
6 -11.4003jck_I mol:protein length:89 26S proteasome complex subunit SEM1  ali model follow..  5  2...................................................................................................................................................................................................................................................................................STDVAAAQAQSKIDLTKKKNEEINKKSLEEDDEFEDFPIDTWANGETIKSNAVTQTNIWEENWDDVEVDDDFT 74
7 -11.2005cwc_A mol:protein length:210 Designed helical repeat protein  ali model follow..  9  1..................................................................................................................................................................................................................MSSEKEELRERLVKICVENAKRKGDDTEEAREAAREAFELVREAAERAGIDSSEVLELAIRLIKECVENAQREGYDISEACRAAAEAFKRVAEAAKRAGITSSEVLELAIRLIKECVENAQREGYDISEACRAAAEAF 138
8 -11.1005d23_A mol:protein length:102 Fibroin-modulator-binding protein-1  ali model follow..  7  1..........................................................................................................................................................................................................................................................METSEERAARLAKMSAYAAQRLANESPEQRATRLKRMSEYAAKRLSSETREQRAIRLARMSAYAARRLANETPAQRQARLLRMSAYAAKRQASKKS.. 96
9 -11.1006eu0_Q mol:protein length:251 DNA-directed RNA polymerase III subunit RPC7  ali model follow..  6  141.......................................................................................................................................................................................................................................................GINKKKLLAISKFNNADDVFTGTGLQDENIGLSMLAKLKELAEDVDDASTGDGAAKGSKTGEGEDDDLADDDFEEDEDEEDDDDYNAEKYFNNGDDDDYGD 241
10 -11.0006cnb_Q mol:protein length:251 DNA-directed RNA polymerase III subunit RPC7,DNA-directed RNA polymerase III subunit RPC7,DNA-directed RNA polymerase III subunit RPC7,DNA-directed RNA polymerase III subunit RPC7,DNA-directed RNA polymerase III subunit RPC7  ali model follow..  6  141.......................................................................................................................................................................................................................................................GINKKKLLAISKFNNADDVFTGTGLQDENIGLSMLAKLKELAEDVDDASTGDGAAKGSKTGEGEDDDLADDDFEEDEDEEDDDDYNAEKYFNNGDDDDYGD 241
11 -10.9005m4t_A mol:protein length:73 Variant surface glycoprotein MITAT 1.1  ali model follow..  10  1...................................................................................................................................................................................................................................................................................GSKKQQTESAENKEKICNAAKDNQKACENLKEKGCVFNTESNKCELKKDVKEKLEKESKETEGKDEKANTTGS 73
12 -10.9005cwf_A mol:protein length:191 Designed helical repeat protein  ali model follow..  6  18........................................................................................................................................................................................................................................................LAKKNNDDEVAREIERAAKEIVEALRENNSDEMAKVMLALAKAVLLAAKNNDDEVAREIARAAAEIVEALRENNSDEMAKVMLALAKAVLLAAKNNDD.. 115
13 -10.8006c0f_w mol:protein length:250 Ribosomal RNA-processing protein 15  ali model follow..  12  1..........................................................................................................................................................................................................................................................................MGSKHRVDTKDKKRTRKNAEFGREKRNSGNQELSNEPEKDTIMEGDEAEEDEQNSSSDESSKIIDNEQSDAEEDDDEEEEDD 82
14 -10.8006fhs_H mol:protein length:491 les2  ali model follow..  11  1..................................................................................................................................................................................................................MSTRPRRHAAQRASQAITDLADRDRESDHSHGPISSRMSSFNSSSRSRLPGKGIASVSRSEAGGASDPEHIHLTVKLPSSKLRQATSSSGIKKAGSVGSSSSSSGGGKAAVKRARGGKRSRVLESSEEEEEENEVEVL 138
15 -10.8005iy6_S mol:protein length:517 General transcription factor IIF subunit 1  ali model follow..  10  92........................................................................................................................................................RPEDQPWLL-------SGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEP 285
16 -10.8005chl_A mol:protein length:74 Vacuolar protein sorting-associated protein 72 homolog  ali model follow..  9  1................................................................................................................................................................................................................................................................................AASRSRRNNAGNKIAHLLNEEEEDDFYKTSYGGFQEDEEDKEYEQKDEEEDVVDSDFSIDENDEPVSDQEEAPE.. 74
17 -10.7005nrl_N mol:protein length:291 Pre-mRNA-splicing factor SPP381  ali model follow..  10  7....................................................................................................................................................................................................................................................................KRRLDTSSADESSSADEEHPDQNVSLTEKSASLSHSDLGGEILNGTGKNRTPNDGQESNESDGSPESDESPESEESSDNSDSSDSDDM 94
18 -10.5005cwq_A mol:protein length:239 Designed helical repeat protein  ali model follow..  10  2.....................................................................................................................................................................................................................................NSEELERESEEAERRLQEARKRSEEARERGDLKELAEALIEEARAVQELARVACERGNSEEAERASEKAQRVLEEARKVSEEAREQGDDEVLALALIAIALAVLALAEVACCRGNSEEA 120
19 -10.5005on6_i mol:protein length:272 Suppressor protein STM1  ali model follow..  8  14...................................................................................................................................................................................................................ADVVVLPPKEIVKSNTSSKKADVPPPSADPSKARKNRPRPSGNEGAIRDKTAGRRNNRSKDVTDSATTKKSNTRRATDRHSRTGKTDTKKKVNQGWGDDKKELSAEKEAQADAAAEIAEDAAEAEDAGKPKTAQLS. 149
20 -10.4005w3n_A mol:protein length:241 RNA-binding protein FUS  ali model follow..  7  7...................................................................................................................................................................................................................DIPTTENLYFQGAMDPASNDYTQQATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTDTSGYGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSY 143
21 -10.3005j0l_A mol:protein length:141 designed protein 3L6HC2_2  ali model follow..  8  25...........................................................................................................................................................................................................................................ADSNAKAAEDLMREIARSSSSERLLELMAEAIRELQKQAAESIADSQRLVVEAIIRLAEAVKQGASEKEIDEIVEEAKKRLEELAERSRQENKKIIDRAKYEMDEESGSLE.. 135
22 -10.2006e11_d mol:protein length:993 Translocon component PTEX150  ali model follow..  6  6..............................................................................................................................................................................................................LALLIVCTIINYYCAVQNNGNKSLNVMPTCSMPGNDSDSNDNETGDVDNDKNNELGNANDNNEMNNENAESKNMQGENSNNQEQLNENVHANDDAMYEGTPSSDNPPQENVDANNNEQEYGPPQEEPVSENNVENVEVATDD 147
23 -10.1005cwh_A mol:protein length:172 Designed helical repeat protein  ali model follow..  8  35....................................................................................................................................................................................................................ELAKQSTDSELVNEIVKQLAEVAKEATDKELVIYIVKILAELAKQSTDSELVNEIVKQLAEVAKEATDKELVIYIVKILAELAKQSTDSELVNEIVKQLEEVAKEATDKELVEHIEKILEELKKQSTDGWLE.... 166
24 -10.1003cx5_F mol:protein length:146 Cytochrome b-c1 complex subunit 6  ali model follow..  14  11..............................................................................................................................................................................................................................................................................EQLKITVVPVVAAAEDDDNEQHEEKAAEGEEKEEENGDEDEDEDEDEDDDDDDDEDEEEEEEVTDQLREHFKNTEEGK 91
25 -9.9805vjs_A mol:protein length:196 Reaction Center Maquette  ali model follow..  4  2...................................................................................................................................................................................................................SPELRQEHQQLAQEFQQLLQEIQQLGRELLKGELQGIKQLREASEKARNPEKKSVLQKILEDEEKHIELLETLQQTGQEAQQLLQELQQTGQELWQLGGSGGPELRQKHQQLAQKIQQLLQKHQQLGAKILEDEEKH 138
26 -9.8801xu6_A mol:protein length:80 Variant surface glycoprotein MITAT 1.2  ali model follow..  5  1.............................................................................................................................................................................................................................................................................GSHMLEVLTQKHKPAESQQQAAETEGSCNKKDQNECKSPCKWHNDAENKKCTLDKEEAKKVADETAKDGKTGNTNTTGS 79
27 -9.6403pgw_S mol:protein length:437 U1-70K  ali model follow..  7  303...................................................................................................................................................................................................................RERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGYLAPENGYLMEAAPE.. 437
28 -9.5304wse_A mol:protein length:584 Putative poly(A) polymerase catalytic subunit  ali model follow..  3  447....................................................................................................................................................................................................................RMNRLRLLEKRKQGKQTSFVYTPEDFFKKDLETQAKLDPSKARFKNTSGNKIMVPKYLLFKIDNNGNIEDNIHSEEAEISEKEETSGGSSISTDKSFEESPNSSPNSSPNNSLNNSIDISTNNYDDRSENSLDSLT 582
29 -9.5306cvj_D mol:protein length:206 Microtubule-associated protein tau  ali model follow..  7  1..................................................................................................................................................................................................................YSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGRLQTAPVPMPDLKNVKSKIGSTENLKHQP 138
30 -9.4805kbw_A mol:protein length:181 Riboflavin transporter RibU  ali model follow..  8  5......................IKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFF---LMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKVSSILKL......................................................................................................................................................... 174
31 -9.4305kc0_A mol:protein length:190 Riboflavin transporter RibU  ali model follow..  8  4......................IKKISFVGIFSALATLVMFLEFPIFPQASFLKYDPSEIPALIVSFLLGPGVGMFVVLVKDILFF---LMKSGDPVGIAMNAVLGMSFVGIAGLIYHRNKSRATAIKGMIVATLFATAFALGLNALIVPLYFEAPFELYLKFFPFILAFNLVKFGIDSVVTFFVYKKVSSILKL......................................................................................................................................................... 173
32 -9.4205z3g_b mol:protein length:427 rRNA-processing protein EBP2  ali model follow..  14  7...................................................................................................................................................................................................................LKELLSHQKEIEKAEKLENDLKKKKSQELKKEEPTIVTASNLKKLEKKEKKADVKKEVAADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDD 143
33 -9.2304wjg_E mol:protein length:343 Haptoglobin-hemoglobin receptor  ali model follow..  7  177...................................................................................................................................................................................................................KAIDAAANVGGLSAHKSKYGDVLNKFKLSNASVGAVRDTSGRGGKHMEKVNNVAKLLKDAEVSLAAAAAEIEEVKNAHETKAQEEMKRNGNPIENESETNSGGNAESQGNGDREDKNDEQQQVDEEETKVENGSS.. 311
34 -9.2205nnv_A mol:protein length:282 Chromosome partition protein Smc,Chromosome partition protein Smc  ali model follow..  10  106...................................................................................................................................................................................................................ETLQAEVKQLRAQVKEKQQALSLHNENVEEKIESGGSGGSRLTKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKKELTETELALKEAKEDLSFLTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELI 242
35 -9.1105fug_C mol:protein length:68 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG  ali model follow..  12  3...........................................................................................................................................................................................................................................................................................HMGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEG.. 65
36 -9.0805o9z_K mol:protein length:439 Microfibrillar-associated protein 1  ali model follow..  8  43.........................................................................................................................................................................................................KRPDYAPM--DEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTD 190
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;