current user: public
If you have questions about the server, please let us know.

Query: [E] COG0002 Acetylglutamate semialdehyde dehydrogenase, from VFDB

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .
# Score Template Links and tools%idFirst MKVGIIGASGYTGGELLRLLVSHPDVRLELATSRSLAGKPVSSTHRHLTGFLDLKYENPVSEEIRERCDVVFVAVPHGTAMNYVPELLDGSTKVIDLSADYRLDTPVFENIYGIKHSDPRKAVYGLVELHPEAAREEFVANPGCFPTGANLAAAPLAAAGLIDIAVFDSKTGISGAGISPTETSHYPNIAENIIPYKLTAHRHRAEILQELTRLDGKLRNISFTPHVIPSIRGILTTAHLFTKEPLSTGDVQEIYEEFYRDKPFVRLPGGVPSLTAVRGSNFCDIGFEADKENNRVVVLSAIDNLVKGASGQAIQNMNLMFGLAETRGLWLPAAAPLast
1 -41.600PF01118.24; DHAS_YEAST/6-132; Semialdehyde dehydrogenase, NAD binding domain  ali follow..  20  2..AGVLGATGSVGQRFILLLANHPHFELKVLASSRSAGKKYVDAVNWKQTDATDIIVSECKSEFFKECDIVFSGLDADYAGAIEKEFMEAGIAIVSNAKNYRREQDVPLIVPVVNPEHLD........................................................................................................................................................................................................................ 125
2 -30.500PF02774.18; DHAS_ECOLI/144-353; Semialdehyde dehydrogenase, dimerisation domain  ali follow..  15  1........................................................................................................................................................LGGLFANDLVDWVSVATYQAASGGGARHMRELFGVPLAGSLIPWDNGQSREEWKGQAETNKILSSVIPVDGLCVRVGALRCHSQAFTIKLKKDVSIPTVEELLAAHNPWAKVVPNTMRELTPAAVTGTLTTPVGRLRKLGPEFLSAFTVGDQLL.............................. 209
3 -13.100PF01113.20; DAPB_VIBCH/2-125; Dihydrodipicolinate reductase, N-terminus  ali follow..  13  1VRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVDNLEQAVEQFDVIIDFTAPASTLANLALCEQHGKKLVIGTTGFTDAQ--------------------RQTIEQAAKKIPIVMAPN................................................................................................................................................................................................. 123
4 -10.400PF03435.18; Q94BZ0_ARATH/41-165; Saccharopine dehydrogenase NADP binding domain  ali follow..  14  1..VLVLGGTGRVGGSTATALSKLCPELKIVVGGRNR--EKGEAMVAKLGENSEFSQVDINDETSLRDVDLVVHAAGQAPRCTVLEAAIKTKTAYLDVCDDTSY......................................................................................................................................................................................................................................... 106
5 -10.100PF02629.19; SUCA_CAEEL/31-124; CoA binding domain  ali follow..  14  5.KVIVQGFTGKQGTFHGKQMLEYNTKVVGGVNANKAGTEHLG------------VFKNVSEARNKTGADASVIYVPASAAGSAIEEAMDAEIPLV................................................................................................................................................................................................................................................. 88
6 -9.920PF02670.16; DXR_PARUW/4-128; 1-deoxy-D-xylulose 5-phosphate reductoisomerase  ali follow..  11  1..IAILGSTGSIGKNTLQVARHLKEIKVVAIAARENIDAQSKEFCPDIIAVFNNAKAYELQKRSYSEADLVISAMTGTMGLQPTIEAIKAGKDVG................................................................................................................................................................................................................................................. 114
7 -8.780PF10727.9; Q743Y6_MYCPA/8-128; Rossmann-like domain  ali follow..  20  5LKVGIISA-GRVGTALGVALERADHVVVACSAISHASRQRAQRRLPD--------TPVATPPEVAAGAELLLLAVPDSELAGLVSGLAAAGTIVAHTSGANGVG........................................................................................................................................................................................................................................ 104
8 -8.660PF00044.24; Q8KCE2_CHLTE/4-104; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain  ali follow..  12  1VKVGING--GRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLYDSSHKKFNGEVTIEGDNLIVNGRTIAICAQKDPAQLPWASLGAT---LVVESTGIFT.......................................................................................................................................................................................................................................... 99
9 -8.290PF04321.17; RMLD_SINFN/1-291; RmlD substrate binding domain  ali follow..  16  1MRLAVTGKNGQIALALKAQAR--PDVEILTLGRPNFDLACRSTVASSIRDAAPDIIVSLAAYTAVDKAE-EAFAVNRDGVQALAEAAAGLGVPVIHLSTDYVFDGAKPVPYCEEDRTGPIS-VYGRSKLEGELRTSWVYSRYGQNFVKKMLRLADTNDE----NVVADQLGCPTSA................................................................................................................................................................ 185
10 -7.930PF07993.12; Q9VLJ7_DROME/16-287; Male sterility protein  ali follow..  13  1....VTGGTGFLGKVIIEKLLRSTDVRRVYLLVRPKKNETVEGRFQAWKDEPVFKILLKAKPEALKLVTPICSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPL-----------------------------QRALNINTRATRLMIQLAKEMKG----EAFVHISTAFSNCPSQHIEERF----------YPEHLTCPAAKVLEFNETLSPDLLDMGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYGNTYGILRLLYVNPKADAIIVPGDYCANVA........................... 272
FFAS is supported by the NIH grant R01-GM087218-01
1 4 4 8 1 6   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.