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Query: [E] COG0002 Acetylglutamate semialdehyde dehydrogenase, from VFDB

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKVGIIGASGYTGGELLRLLVSHPDVRLELATSRSLAGKPVSSTHRHLTGFLDLKYENPVSEEIRERCDVVFVAVPHGTAMNYVPELLDGSTKVIDLSADYRLDTPVFENIYGIKHSDPRKAVYGLVELHPEAAREEFVANPGCFPTGANLAAAPLAAAGLIDIAVFDSKTGISGAGISPTETSHYPNIAENIIPYKLTAHRHRAEILQELTRLDGKLRNISFTPHVIPSIRGILTTAHLFTKEPLSTGDVQEIYEEFYRDKPFVRLPGGVPSLTAVRGSNFCDIGFEADKENNRVVVLSAIDNLVKGASGQAIQNMNLMFGLAETRGLWLPAAAPLast
1 -41.600PF01118.24; DHAS_YEAST/6-132; Semialdehyde dehydrogenase, NAD binding domain  ali follow..  20  2..AGVLGATGSVGQRFILLLANHPHFELKVLASSRSAGKKYVDAVNWKQTDATDIIVSECKSEFFKECDIVFSGLDADYAGAIEKEFMEAGIAIVSNAKNYRREQDVPLIVPVVNPEHLD........................................................................................................................................................................................................................ 125
2 -30.500PF02774.18; DHAS_ECOLI/144-353; Semialdehyde dehydrogenase, dimerisation domain  ali follow..  15  1........................................................................................................................................................LGGLFANDLVDWVSVATYQAASGGGARHMRELFGVPLAGSLIPWDNGQSREEWKGQAETNKILSSVIPVDGLCVRVGALRCHSQAFTIKLKKDVSIPTVEELLAAHNPWAKVVPNTMRELTPAAVTGTLTTPVGRLRKLGPEFLSAFTVGDQLL.............................. 209
3 -13.100PF01113.20; DAPB_VIBCH/2-125; Dihydrodipicolinate reductase, N-terminus  ali follow..  13  1VRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVDNLEQAVEQFDVIIDFTAPASTLANLALCEQHGKKLVIGTTGFTDAQ--------------------RQTIEQAAKKIPIVMAPN................................................................................................................................................................................................. 123
4 -10.400PF03435.18; Q94BZ0_ARATH/41-165; Saccharopine dehydrogenase NADP binding domain  ali follow..  14  1..VLVLGGTGRVGGSTATALSKLCPELKIVVGGRNR--EKGEAMVAKLGENSEFSQVDINDETSLRDVDLVVHAAGQAPRCTVLEAAIKTKTAYLDVCDDTSY......................................................................................................................................................................................................................................... 106
5 -10.100PF02629.19; SUCA_CAEEL/31-124; CoA binding domain  ali follow..  14  5.KVIVQGFTGKQGTFHGKQMLEYNTKVVGGVNANKAGTEHLG------------VFKNVSEARNKTGADASVIYVPASAAGSAIEEAMDAEIPLV................................................................................................................................................................................................................................................. 88
6 -9.920PF02670.16; DXR_PARUW/4-128; 1-deoxy-D-xylulose 5-phosphate reductoisomerase  ali follow..  11  1..IAILGSTGSIGKNTLQVARHLKEIKVVAIAARENIDAQSKEFCPDIIAVFNNAKAYELQKRSYSEADLVISAMTGTMGLQPTIEAIKAGKDVG................................................................................................................................................................................................................................................. 114
7 -8.780PF10727.9; Q743Y6_MYCPA/8-128; Rossmann-like domain  ali follow..  20  5LKVGIISA-GRVGTALGVALERADHVVVACSAISHASRQRAQRRLPD--------TPVATPPEVAAGAELLLLAVPDSELAGLVSGLAAAGTIVAHTSGANGVG........................................................................................................................................................................................................................................ 104
8 -8.660PF00044.24; Q8KCE2_CHLTE/4-104; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain  ali follow..  12  1VKVGING--GRIGRLVFRQAMENPEIEIVGINDLTDVKTLAHLLYDSSHKKFNGEVTIEGDNLIVNGRTIAICAQKDPAQLPWASLGAT---LVVESTGIFT.......................................................................................................................................................................................................................................... 99
9 -8.290PF04321.17; RMLD_SINFN/1-291; RmlD substrate binding domain  ali follow..  16  1MRLAVTGKNGQIALALKAQAR--PDVEILTLGRPNFDLACRSTVASSIRDAAPDIIVSLAAYTAVDKAE-EAFAVNRDGVQALAEAAAGLGVPVIHLSTDYVFDGAKPVPYCEEDRTGPIS-VYGRSKLEGELRTSWVYSRYGQNFVKKMLRLADTNDE----NVVADQLGCPTSA................................................................................................................................................................ 185
10 -7.930PF07993.12; Q9VLJ7_DROME/16-287; Male sterility protein  ali follow..  13  1....VTGGTGFLGKVIIEKLLRSTDVRRVYLLVRPKKNETVEGRFQAWKDEPVFKILLKAKPEALKLVTPICSEPGLGLSDGDRRMVTADVQVIIHSAASIRFVEPL-----------------------------QRALNINTRATRLMIQLAKEMKG----EAFVHISTAFSNCPSQHIEERF----------YPEHLTCPAAKVLEFNETLSPDLLDMGKFPNTYTYTKALAEQVIQMEGQDLPICVFRPAIILANFKEPMSGWIDNLHGVVALIYGNTYGILRLLYVNPKADAIIVPGDYCANVA........................... 272

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Li Z, and Godzik A. Modeling and Analyzing Three-Dimensional Structures of Human Disease Proteins Pacific Symposium on Biocomputing 11:439-450(2006) [PDF]