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Query: [H] COG0007 Uroporphyrinogen-III methylase, from VFDB

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKADEAAACVIAKSKVALPVMEPGHVWLVGAGPGDPGLLTLHAVNALQQADVIVYDALVDDSCLSLKNATATLEYAGKRGGKPSPRQRDISLRLVELARQGKKVLRLKGGDPFVFGRGAEEALTLVEYHVPFRIVPGVTAGVGGLAYAGIAATHRDINQAVTFLTGHDATGAMPDGVDWAGIARSSPVIVMYMAMKHIGLIAGRLIEAGRSPDEPVAFVCNASLPDQTVLETTLGRAAIEVEAAGLQPPAIVVVGEVVRLRAGLDWIGAMAGKSLVSDPLGKRTQQGVQSALast
1 -65.300PF00590.20; Q3A6A0_PELCD/39-272; Tetrapyrrole (Corrin/Porphyrin) Methylases  ali follow..  23  1.........................HFYLVSVGCGDADNITLKAMRTIQSADIVYCSKKNRENYPELIKDKKGNFGFGKSKGEDLAAKENFVRTVTTAVRAGKNVCLLDGGDPCIFGPYIWTVEVL--QDLDPVIIPGVSCLNAANAALHRGLTFGVAAHSAILTNAADTKPGYGGSDTIARMAATRASMVVFTMFSDMEKLVAELGR-FYPPDTPVAIVARGYAKDEQVIRGTLESI...................................................... 233
2 -7.380PF01890.16; K9VGP0_9CYAN/96-268; Cobalamin synthesis G C-terminus  ali follow..  14  105MLDNRQDACATILNNRQDACEAKSESACGVGILPAREKLLVPKQIFRSKNPPLSK............................................................................................................................................................................................................................................. 159
3 -5.620PF17941.1; A0A0A1MN06_9BACI/337-503; Polyphosphate kinase C-terminal domain 1  ali follow..  15  3............................................LEAVRKRDLFLHHPYES-DLMREAADDPEVLAI-KQTLYRVSGDSPIIASLKRAAENGKQVVELKA-------RFDEAAKQLEIAGC--HVIYGMI---SLKTHSKITLIVRKHENRIHLGTGNYNDQTAKFYTDMSFLT............................................................................................................ 145
4 -5.530PF12852.7; C6W9P9_ACTMD/20-189; Cupin  ali follow..  11  1........................................................DPV--RQVLALARPRAVVPAPLRATAPWGARFSPFPHIKLGVVAEGEFWLCVDGLEPILLRAGD---FYLLGNPPAYGL-------GSSVETAREGISGNGPGAFAYTCTVD-----------------------FEFRDADASTLFSAL---------PPAVVVRADETGGQLLWNIATLLVHEFQEPRTGQSLVL-LAQILLVHMLRSHAD....................... 170
5 -5.340PF12577.8; G1KNP4_ANOCA/39-116; PPAR gamma N-terminal region  ali follow..  24  10................................................................................................................PMNFGISPVDLSAMDEHSHSFDIKPFTTSSLSSPHYEDLALARTD....................................................................................................................................... 57
6 -5.120PF15632.6; W0LEM0_9GAMM/205-340; ATP-grasp in the biosynthetic pathway with Ter operon  ali follow..  13  4...................................................PLVLMPYLPGPEYVDMLVERGNVLAAVARRKEGALQYLEHHGEALELATACATAMEADGLVNVQTRNDASGHPLL------LEINLRPSGGIGYTRFSGVNLPG......................................................................................................................................... 102
7 -5.020PF06676.11; S5XXI8_PARAH/1-135; Protein of unknown function (DUF1178 topsan)  ali follow..  19  85........................................................................................DYVGMSFAAEAR------AMHDGTK-IHGEAKEDARKLLEDGIPVAPLPFTPR....................................................................................................................................................... 135
8 -5.010PF16265.5; W0EUS5_9BACT/3-226; Domain of unknown function (DUF4918 topsan)  ali follow..  9  55......................................................................................................................................FIIGINPSRHGAGVTGVPFTDTKRLEKVCGIKMESYTHEVSSVFMYDMITAWGGARSFYKNFYINSPFPLAIIRRANEGKWLNANYYDDPKLFEMVKPFMIASLEKHISLG-LDTSEVFILGKKNATFINQLNATAGLFSKATVLEHPRYIEQYKSK. 211
9 -4.990PF18297.1; A0A2H1EF31_9ARCH/246-347; NFACT protein RNA binding domain  ali follow..  12  1.....................................................................................................GRHF-RFDKNTKLIVGRHKDENEMIKALALPGDTLFEAKDHVGPVSILRGDDSEKNQKLAASITLRYSDAPKDAQ.................................................................................................................... 74
10 -4.950PF17010.5; J9DTR0_EDHAE/41-255; Domain of unknown function (DUF5092 topsan)  ali follow..  12  1....................................PETFTLEEFRKI------VIEFRKNNKDCIIARISTPDHDRSDVLFNNYYVASEVNKLLFKYERDRRLLHRMKVRNPL.................................................................................................................................................................................. 72
FFAS is supported by the NIH grant R01-GM087218-01
1 4 4 8 1 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.