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Query: [L] COG1039 Ribonuclease HIII, from VFDB

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNIVLKLETKERQQLAEKYKSYEQVSKNPYITFFAKVGKTSISVYTSGKVVFQGNEAEKLASDFGHIAQVVPQKQTNLIGTDEVGNGSYFGGLMVTASFVSEENLNFLKEIGVADSKKLTDEKICQIAPKLIDRIPHVALVVEPAKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGHKPENIVIDAFTTEANYKKYVNKEQNHPLTKVTLLTKAEDQFLAVAVSSIISRYLFLENLKKLSKESGFTLPSGAGNLSDKIAAQIIKSQGVDALNQLAKLHFANTQKAIKIAQLLast
1 -63.800PF01351.18; RNH2A_SCHPO/66-277; Ribonuclease HII  ali follow..  19  1..............................................................................LGVDEAGRGPVLGPMVYAVAYCPVDF--DLTNYGFADSKTLASLKREELLKLICNKVGWSTMSISARELAAGMLRYRNKYNLNLQAHDTTIDLIKKESGINVTEIYVDTVGPPISYQEKLQAH--FPQAKVTVTKKADSLFPIVSLASICAKVTRDIQLECARESIR-TENWGSGYSSDARTTEWLKVNVDKIFGDIVRYSWKTA......... 212
2 -20.400PF11858.8; RNH3_OCEIH/3-77; Domain of unknown function (DUF3378 topsan)  ali follow..  29  1.QQVIVTTKEQIQKMKKYYLSQLT-STPQGAIFRAKTNNAVITAYQSGKVLFQGSAPESEASKWGNVPLNDKKKHS........................................................................................................................................................................................................................ 74
3 -7.790PF12686.7; K9XG69_9CHRO/9-227; Protein of unknown function (DUF3800 topsan)  ali follow..  8  1.............................................................................ALYLDDSGSPKP---FGMGGVLINRGHEQIIEA-NYDWLGNLSEVEYQQFMEDLTNTIVRCPIIVHACVISRHGYLKRDTWEMMKSAFTILVERAAKYVAAKNGTVYFEAAGKRERANKYFPLSANDFSSLLRGIDSKKKSNAVMQIADLCL............................................................... 213
4 -7.200PF06866.11; Q899R5_CLOTE/6-172; Protein of unknown function (DUF1256 topsan)  ali follow..  12  1...........................................IINSNSKSAIITLRDTLCGYITPVLASGKHIILLCIGSDRS-TGDSLGPLV--GHNLKFLSRNNFHVFGNLE-MPVHAKNLHQILKYINKKFDDPYIIA----VDACLGHIQNIGKVFVLKPGSAVNKDLPPVGNLSITGIVNISGTLE-----------------FMVLQNTRLFTVMQLAELISN.............................................................. 166
5 -7.130PF05161.13; A0A068NUP3_9BACT/318-423; MOFRL family  ali follow..  20  7.....................................GETTVTVRGSGI----GGRCQEMVVAAAPAVAKLADTAFLAAGTD--GAD---GPTEAAGGLVETDSLRLAKEVGNDQRKALVNNDSFRYLLQCDGLL............................................................................................................................................................. 95
6 -6.190PF08218.11; Q8DUD0_STRMU/148-328; Citrate lyase ligase C-terminal domain  ali follow..  9  8.........................................................................................ANPFTLGHQYLVEKAAAENELLHLDDSSLIPFSVRKQLILAGTEHLS-NICYHETGPYSYFQKDQASVIESQARIDLAIFIQIAKYLGIKGRYVGEEPTSVTGIYNQIMLQELPKQAIDCIVVPRKTYKDGPISASTVALKEGNEQILRELLPS................................................. 175
7 -6.120PF17289.2; F0LQ02_VIBFN/424-584; Terminase RNaseH-like domain  ali follow..  7  1..............................................................................LGYDPSRTRDNA---VLMVVAPPIVAAEKFRVLEKHTWRGLSFQHQASEIDKVFERFNVTYLGIDIDLLSNKHPRETVAIHYSNENKNRLVMKMIDVIDGQRLQFDAGMKETAMSFMAIKRTSTNSGNMMTFKADRSELVHADDFWALSHA............................................................... 157
8 -5.920PF16189.5; R6AXD3_9BACT/152-308; Creatinase/Prolidase N-terminal domain  ali follow..  17  17...................................................FAGESVASKISRIRTALRQRHADGMLISALDDIARGT-CVPVFVSYLLISSQQVSLY------DSAKINDEVKAYLTEN-----------ILLYPYNKVAEGLERYSE---------------------YNILLDGDETSYFLWKTVKCKEIIAGNSPVPAMKA............................................................................. 151
9 -5.880PF08303.11; Q6CK12_KLULA/389-554; tRNA ligase kinase domain  ali follow..  11  2...........................................................................................................LVTIATIGCGKST------VSLTLNELFPESWGLVVNDNITS--------------NKTDYIKSALQLFKDGKQFVLADKNNHQFRERAAVFEWINQYRDSYIPYLQVIALCFVDEVSPEMRALTIDRVMKRGDNHQSIKSESDDQQKVLKIMQGFMNRFQPFLPSKDPDNKFDFHIQL...... 163
10 -5.770PF13872.6; E4XRW5_OIKDI/32-343; P-loop containing NTP hydrolase pore-1  ali follow..  13  6VIESIALSSVTVPDVATKI-SLPMDIVEEGKLSDLQLEAVVYAKQQHAGFYPSGERK------------------GFLLG-DGAGVGK--GRSISGIIYLRHDSLRDLNDIGADMIKVHPLHKFKYGHKLTDKENGRVQEGVIFGTYASLIGERHQAGATTKRAAQATLHQLVTWCGRNFDGCIVDECHKAKNLYQANGKPSKTGTTVLELQRQLKQARIVYASATGASEPKHMSYMSRLGL-------AGTGFKSSEQFVDALTKAGV-GAMELVAMDMKRRGVYLARQL. 288
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.