current user: public
If you have questions about the server, please let us know.

Query: [K] COG3888 Predicted transcriptional regulator, from VFDB

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .
# Score Template Links and tools%idFirst MSLRDVLLRELKRARGLGIDQFQIEEMMGFSKSTVSEALKDLEEKGIIKRRTIGGKIKHVWLAEYYPYYDEKLLRIGCLRSTEYVKFVSVAKNYSESKGIDLIVRFYDDAISLMNDLSQGLLEFALAPIFTEIIYSISNRNSIILGAVASGGSGVYKNVNCNCGKILTSESSSMMILAREFAKTRKISEIAIFKDPRRAIKDYESFKAEYIVIWEPYASKIMGEKMASFSDVLDSFPCCGISVSENNRENRTLIEIVRLYKRSRFTAREDVIDIFAKSTSVSPKTAKASLENYIWDIKFYRSDLKKYLEFIGYPPIEEIIEKIYEEVLast
1 -44.300PF13379.6; B0UDN0_METS4/41-302; NMT1-like family  ali follow..  11  1..................................................................TGPEVKGAKLGFIALTDAPLFVAKEKGFFAKHGMEVEVLKQASWGTTRDNLVLGSEGNGIDGAHIRVTQNNVPVPMHILARLNLNGQCISDKKKAAGKSVKAAPGGTHDLWIRYWLAAGGIDIETIVVPPPQMVANMKVGTMDCFCVGEPWNAQLVGYTALTTGELWKDHPEKAFAMRADWKYPNATRALLMAVIEAQQENRDEFAAIVA................................................... 262
2 -31.200PF14503.6; F4GIV3_SPHCD/83-314; YhfZ C-terminal domain  ali follow..  7  14...........................................................................VGVMPSKRYEGLATGISTSMNKGKMRTSLVFSRGADNRLEGILEQRYDFAVVSRLAAEHYVEKQYPIVIAHLVTCRNGVNLKAQDFSNCRIGVDEASTDQRILSHRFFRDT-QVTYVPIVYNQVIPALKGNDIDATIWNADALDARKNGIFSFPLEQISQDDTEAAIIHL--AGKPFISRILAELLNPDEVLEYQKKVMAGACM................................................ 229
3 -28.700PF09084.11; M7UJG4_BOTF1/16-238; NMT1/THI5 like  ali follow..  11  6.....................................................................................VYLAQKLGYFADEGIKVALLEPNDPSDVTEIIGSGKVDMGFKAMIHTLAAKARDFPVTSIGSVYLKDSGITTFRSLKGKKIGYV-GEFGKIQIDELTKYYGMEPTDYEAVR-NVSKAIIEGSIHAGIGLENVQMVELEEWLANQGRPCCCFCSILYIANDAFQNPEKVRKFMKAVKRATDGSPSDA........................................................ 223
4 -28.600PF12916.7; A4YDV4_METS5/1-196; Protein of unknown function (DUF3834 topsan)  ali follow..  12  12............................................................................................................SYPMIASTMKNKDIIIDFG--------KDGSADVILDSTVSLVIKGLMVVSPDVGKRIGVWRGSAADVLTRALLDKKGIRGEVVYAEMPRLVEMLNKKEVDSIVIASPFAKGKTFEELLG------------IPGSCGASVNANHEEFISAYSEGIEQDPQGVAEYVAKKLPINLQMIVNLPKTTVLT............................... 196
5 -19.400PF02621.14; B9M1W5_GEODF/4-263; Menaquinone biosynthesis  ali follow..  11  1.........................................................................LSLGYSPCPNTFIFHALVHGLVSKPGLIFNER-LEDVETLNRLVLEKTLDVSKISYHLLGYVREDYCLLSAGGALGRGCGPLVSMDQLKGKRIALPGRYTTAALLLRLFDPALTDIIYLPFD--RIMGAIADGSVDAGVIIHESRFTYAGLGLVKLLDL---IPLGGIVAKRSLGSEAGINSLLRQSVELAFAYPGKANAYIRANSEMSDEVCAAHIDLYDFSKDLGHEGKAAVNTLMGRAEA........... 260
6 -15.800PF03180.14; M9X5A7_MANHA/27-263; NLPA lipoprotein  ali follow..  15  1.........................................................................LKVGVISGPEHKVMEVAAKIAKEKYNRDVELVVFTDYATPNAALDKGDLDLNAFQHKPYLDNQIQEKGYKLVPVGNT-SKKIKSLAELDGDTIAVPNDPTNLARALILLEKQDLTSVDIIENPRKLLLPRTLDDVAFSIINTTYAGQNTPTKDGIFVEDKDSPYVNLIVARENNQHSEAVKDLVKAYQT------EEVYNKANEEFK............................................... 230
7 -14.100PF02916.15; Q8DZD3_STRA5/72-187; DNA polymerase processivity factor  ali follow..  13  46................................................................................................................................................MSVVVPKDSKITNIEAVSKLAAPVKNDTSITDLIEHIKSEKGISITPQTDSYQDAYNRIKSGDSQAMVL.................................................................................................................. 116
8 -13.800PF04069.12; Q880U3_PSESM/23-307; Substrate binding domain of ABC-type glycine betaine transport system  ali follow..  10  2........................................................................SITPIFPSIAEERFRGEIAMAGLKELGYKVEQPKETDYPAMMLALSYGDADFTV-LHASFYAKAGGDDTMVKVGAIMPGVLKITSVEDLKADMTGCNPGWGCEVLVEHHMKAYGLEKTVTDNRGSDTIARYQQGKPILYFTWVPISSVLIEGRDVVWLTVPKTDLPGGKNDVDTTYKGKNLDTVRAVLNKEFAEKNPVAVKFLSE-MQITTDDESAQNLKMHNGENSAADIKRHAAEWIA............... 284
9 -13.500PF16868.5; Q2SNF1_HAHCH/34-328; NMT1-like family  ali follow..  8  8............................................................................GTYYPVGVAIATLTKVKLQPTHKIGISAISSAGSAENIKLMRDNEAQFSILQGLFGKYAWEGSGVFAVLDNEYVKTGTISDLVNAKGERLALSKNSGTIESNRTILANFGLDLDKLYAGYGPSSQALQDGKVVGMGT--PVGAVINPEQIQQADNGFDLWTPFTVKAGVYPGVNKDIVTIQPNFLAVRDDIDEETVYLLTKAIYENLPFLNSI...................................... 263
10 -13.400PF12974.7; D0KYK9_HALNC/62-317; ABC transporter, phosphonate, periplasmic substrate-binding protein  ali follow..  11  1...........................................................................IGVLAYQGKAQTASTAAYLSEKNPGYSFHIEPMFLSELAAAVRENRLDFVLTQPLQFVQLAQNDDVWPLATIVRADRSDLQHVSDLKNKIVAGKDALGAWLLGLDTLVRAGIDPKTQIQPMFQIVEAVWQHRADAGVIRAGFLEQLESQGAVKKGE................................................................................................ 185
11 -13.100PF06163.11; A0A070SGS2_ECOLX/1-127; Bacterial protein of unknown function (DUF977 topsan)  ali follow..  16  12.ELKARIIGLVRKNER--MTISQLERATGAGWHSVRRCLVDVLACGDLYMP.................................................................................................................................................................................................................................................................................... 59
12 -13.100PF00497.20; A6X2Q5_OCHA4/44-271; Bacterial extracellular solute-binding proteins, family 3  ali follow..  7  25.......................................................................................VELMEGVAKQLGLAAEFKDTR---SLITGARANHFDVIASALYKILNFIPYIKAGSSLLVLKDAKFRPANEKELCGKIIGSMQGASWLPKLKALSEDYCAKETREFDTDAQVTQALRSGSVDVEFMDNVLLKKFPDDYAVTSSALIYPIMVGVATTPQNKELFNAMNDAFAQMRK................................................................. 214
13 -12.100PF01978.19; Q8TXT4_METKA/25-102; Sugar-specific transcriptional regulator TrmB  ali follow..  20  9.EDEAELYLKLLENSEEAFTVEDVAEIINRSRSTAQKMLQSLVRVGMVERE.................................................................................................................................................................................................................................................................................... 59
14 -12.000PF04703.12; Q9ADX3_ECOLX/1-62; FaeA-like protein  ali follow..  27  1..MKDNILTFLTELK-TPCRTTEIAIHFGLSAYQARYYLMNLEKEGKIKRS.................................................................................................................................................................................................................................................................................... 48
15 -10.800PF01475.19; FUR_ECOLI/10-130; Ferric uptake regulator family  ali follow..  16  10...RLKILEVLQEPDNHHVSAEDLYKRLEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLT................................................................................................................................................................................................................................ 114
16 -10.600PF04182.12; TFC3_YEAST/107-175; B-block binding subunit of TFIIIC  ali follow..  16  2.NSAFELLLEVAKSGEKGINTMDLAQVTGQDPRSVTGRIKKIN--HLLTSSQL.................................................................................................................................................................................................................................................................................. 51
17 -9.950PF10007.9; A4YIE5_METS5/9-101; Uncharacterized protein conserved in archaea (DUF2250 topsan)  ali follow..  22  8.KRYLMVLQHLRKANV--DYGKSIMLNTKIPIEEVVIILDKLENLGLIERV.................................................................................................................................................................................................................................................................................... 55
18 -9.700PF12793.7; A6TCP6_KLEP7/5-116; Sugar transport-related sRNA regulator N-term  ali follow..  19  6.....RLHARYGAGQTHELQMQEIAAIFGCSVRNCRIALKKMHQEKWLDW--------------QPQRGRGKRSRLHLLTSPEKL-FSQNVNKLLEKQDYGNVLRFIGNDKYLLDRLSL................................................................................................................................................................................................................ 104
19 -9.700PF01047.22; YDGJ_BACSU/52-110; MarR family  ali follow..  34  5...RLELLTLLYHA--DEISQSDLQKKVNIDSAAVTRHLKQLESKGMVSRRR................................................................................................................................................................................................................................................................................... 51
20 -9.670PF03444.15; Q6M165_METMP/2-80; Winged helix-turn-helix transcription repressor, HrcA DNA-binding  ali follow..  12  4.IVQKEILQELISEKNKAVKGTEIAVKLSRNPGTIRNQMQALRALNLVD...................................................................................................................................................................................................................................................................................... 54
21 -9.660PF12802.7; Q28UG0_JANSC/25-85; MarR family  ali follow..  26  9.....QIYALLFLS-STPLNAEQITEGLGVSRSNTSMGLKELQAWNLVRLR.................................................................................................................................................................................................................................................................................... 53
22 -9.560PF09012.10; Q6LTA5_PHOPR/2-67; FeoC like transcriptional regulator  ali follow..  17  1..ILQQLKQYIEQHGR--SSRSNLATHFGMSADGVEAMLAVWIRKGLIGKELVGC................................................................................................................................................................................................................................................................................ 51
23 -9.550PF05732.11; O50587_SELRU/6-169; Firmicute plasmid replication protein (RepL)  ali follow..  26  55.NQKTRLAFWLINNLNRDMTQRKIAEKTGISLETVRQTMKALMESGFLIKINSG................................................................................................................................................................................................................................................................................. 111
24 -9.500PF08220.12; ULAR_ECOLI/6-62; DeoR-like helix-turn-helix domain  ali follow..  22  2...HQILLEMLAQLGF--VTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAI............................................................................................................................................................................................................................................................................. 54
25 -9.330PF07381.11; L0KZ10_METHD/19-105; Winged helix DNA-binding domain (DUF1495 topsan)  ali follow..  21  8.EVRKSILLYLYDIYPLSSYPAEIARRVNANPINVIGAISSLLHLGIISVIEDNGL............................................................................................................................................................................................................................................................................... 72
26 -9.320PF13601.6; Q7MSY5_PORGI/4-83; Winged helix DNA-binding domain  ali follow..  22  1..LRLAIMSVLMSVEE--ADFLYLKEVTGATSGNISVQLDKLSTAGYIEIEK................................................................................................................................................................................................................................................................................... 48
27 -9.250PF01325.19; O28489_ARCFU/1-59; Iron dependent repressor, N-terminal DNA binding domain  ali follow..  16  1MERIEEYLEAIQEETSKVAKTGELAKILNVKPSSVTEMLIKLRDMGYV....................................................................................................................................................................................................................................................................................... 51
28 -9.200PF14947.6; E6N974_9ARCH/5-85; Winged helix-turn-helix  ali follow..  16  5TKIIADILESINQQGH--AKPTKILLDANLSYDRLVKYLDMLVEKKLVERV.................................................................................................................................................................................................................................................................................... 53
29 -9.040PF04492.13; E6WEN5_PANSA/20-114; Bacteriophage replication protein O  ali follow..  18  29...QAKVAHAVCRKKLDRISDSQISELTKLPRQKVNKAKNELIAMRVLVRE.................................................................................................................................................................................................................................................................................... 82
30 -9.040PF12727.7; A0LFW2_SYNFM/425-616; PBP superfamily domain  ali follow..  8  7...............................................................................................RDGRMQLSSG-NVGSLGGLMAVRRAQTHLAGSHLHSYVERYLQGVPIRLVTLAVRQ-AGVRGVRDLARPDVAFQGGSGTRILFDYCLRKEELAPEEIEFTHMAIAVTVLSGRADAGMAIFAAARALGLDFIPVAEERYD------LVIPESFWEDPKMGLLMEIIT.................................................................. 192
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 4 0   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.