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Query: [E] COG0006 Xaa-Pro aminopeptidase, from VFDB

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNQNPIKRLQDSLVERALDAFLIEKDEDISYFLQDQARSGVLLITRDEAVLFVSPLDKDLYARIQDVVLVSYSKSVDQELGSYIENTGLKTIGFDSEYTPYGIAQKRMNSGYAFSPQSLVAEKLRCVKSTEEIQKMTRAAEIGSAGYDFVLAALRPGITEKELVRMLHVFWANLGIEKVSFPPIIAFGENAAFPHAIPTNRSLKKGDVVLIDIGVCYEGYCSDMTRTVAFGATPEQQLLDGYVAVAEAQRAAIEFCRAGVPCRDVHKEAVRILRAHGMEKAFIHGLGHGVGREVHEYPRLSPFSDATLQLNMAVTVEPGVYFPGVGGIRIEDTIMIGVNENLNLTNRKVSSEIIIILast
1 -94.100d1pv9a2 d.127.1.1 (A:125-345) Aminopeptidase P, C-terminal domain {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  36  1...............................................................................................................................KTKEEIEIIEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGS-PNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYGDYFIHSLGHGVGLEIHEWPRISQYDETVLKEGMVITIEPGIYIPKLGGVRIEDTVLITENGAKRLTKTER....... 221
2 -82.700d1chma2 d.127.1.1 (A:157-402) Creatinase, catalytic (C-terminal) domain {Pseudomonas putida [TaxId: 303]}  ali model 3D-neighbors follow..  25  1.............................................................................................................................MIKSAEEHVMIRHGARIADIGGAAVVEALGDQVPEYEVALHATQAMVRAIADTMDTWTWFQSGINTDGAHNPVTTRKVNKGDILSLNCFPMIAGYYTALERTLFLDH-CSDDHLRLWQVNVEVHEAGLKLIKPGARCSDIARELNEIFLKHDVLQYRTFGYGHSFGTLSHYYGRLREDIDTVLEPGMVVSMEPMIMLPGAGGYREHDILIVNENGAENITKFPYGPEKNII 245
3 -64.100d2v3za2 d.127.1.1 (A:177-440) Aminopeptidase P, C-terminal domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  33  1................................................................................................................................SPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSG-HRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVAPGLYIAP--GIRIEDDIVITETGNENLTA.......... 245
4 -45.400d1qxya_ d.127.1.1 (A:) Methionine aminopeptidase {Staphylococcus aureus [TaxId: 1280]}  ali model 3D-neighbors follow..  24  2.............................................................................................................................IVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISANFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLK-VIKNLTGHGVGLSLHEAPAHDPKDKTLLTEGMVLAIEPFISSDKSFVAQIEHTVIVTKDGPILTTKI......... 249
5 -44.800d3tb5a_ d.127.1.0 (A:) automated matches {Enterococcus faecalis [TaxId: 565646]}  ali model 3D-neighbors follow..  21  1...........................................................................................................................MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGES-TPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYG-VVRDFVGHGIGPTIHESPMIEAGKGLRLKEGMVITIEPMVNTDGGLSCQYEHSLAITKEGPRILTSQGEE...... 251
6 -42.000d1xgsa2 d.127.1.1 (A:1-194,A:272-295) Methionine aminopeptidase {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  24  2...................................................................................................................................DTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGK-PAFPVNLSI--NEIAAHYTPYTTVLKEGDYLKIDVGVHIDGFIADTAVTVRVGMEED----ELMEAAKEALNAAISVARAGVEIKELGKAIENEIRKRGFK--IVNLSGHKIEYKLHAGISIRPHDNYVLKEGDVFAIEP----RNGIVAQFEHTIIVEKDSVIVTTE.......... 219
7 -41.500d2ggca_ d.127.1.1 (A:) Methionine aminopeptidase {Escherichia coli K-12 [TaxId: 83333]}  ali model 3D-neighbors follow..  25  3.............................................................................................................................SIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSAYPKSVCISINEVVCHGIPDDKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKP-TIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFS-VVREYCGHGIGRGFHEEPQVSRETNVVLKPGMTFTIEPMVNADRSLSAQYEHTIVVTDNGCEILTLRKDD...... 253
8 -40.900d3tava1 d.127.1.0 (A:3-265) automated matches {Mycobacterium abscessus [TaxId: 561007]}  ali model 3D-neighbors follow..  25  6.........................................................................................................................KKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSGFPASICSSVNDQVVHGIPSAAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTV-IPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIGHGIGRSMHLDPFLAPGKGPLLAVGSVLAIEPMLTLDGSRAAHWEHTVAVTEAGPRILTMRP........ 263
9 -35.300d1b6aa2 d.127.1.1 (A:110-374,A:449-478) Methionine aminopeptidase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  20  51..............................................................................................................................QASEEIWNDFREAAEAHRQVRKYVMSWIKPGMTMIEICEKLEDCSRKLIKEGLAFPTGCSL--NNCAAHYTPNTTVLQYDDICKIDFGTHISGRIIDCAFTVTFN----PKYDTLLKAVKDATNTGIKCAGIDVRLCDVGEAIQEVMESYEVEKPIRNLNGHSIGQYRIHAGKTKGGEATRMEEGEVYAIET-FGSTGKGVVQFEHTILLRPTCKEVVSRGD........ 294
10 -23.700d1chma1 c.55.2.1 (A:2-156) Creatinase {Pseudomonas putida [TaxId: 303]}  ali model 3D-neighbors follow..  16  23.YANRQARLRAHLAAENIDAAIFTSYHNINYYSDFLGRPYALVVTEDDVISISANIDGGQPWRRTVGDNIVYTDWQRDNYFAAIQQAKARRIGIEHDHLNLQNRDKLAAPDAELVDVAAACMRMR....................................................................................................................................................................................................................................... 155
11 -22.400d1pv9a1 c.55.2.1 (A:8-124) Aminopeptidase P {Pyrococcus furiosus [TaxId: 2261]}  ali model 3D-neighbors follow..  20  1........LVKFMDENSIDRVFIAKPVNVYYFSGTSPLGGYIIVDGDEATLYVPELEYEMAKEESKLPVVKFKK--FDEIYEILK--NTETLGIEGT-LSYSMVENFKENVKEFKKIDDVIKDLRII..................................................................................................................................................................................................................................... 117
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.