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Query: [E] COG0040 ATP phosphoribosyltransferase, from VFDB

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGKLLTMAMPKGRIFEEAAGLLRQAGYRLPEEFEDSRKLIIDVPEENLRFILAKPMDVTTYVEHGVADVGIAGKDVMLEEERDVYEVLDLNISKCHLAVAGLPNTDWSGVAPRIATKYPNVASSYFREQGEQVEIIKLNGSIELAPLIGLADRIVDIVSTGQTLKENGLVETEHICDITSRFIVNPVSYRMKDDVIDEMASRLSLVVEGETAKLast
1 -97.500d1o63a_ c.94.1.1 (A:) ATP phosphoribosyltransferase (ATP-PRTase, HisG), catalytic domain {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  37  1....LKLAIPKGRLEEKVMTYLKKTGVIF------ERESSILREGKDIVCFMVRPFDVPTYLVHGVADIGFCGTDVLLEKETSLIQPFFIPTNISRMVLAGPKGRGIPEGEKRIATKFPNVTQRYCESKGWHCRIIPLKGSVELAPIAGLSDLIVDITETGRTLKENNLEILDEIFVIRTHVVVNPVSYRTKREEVVSFLEKLQEVIEHDSNE 203
2 -94.000d1ve4a1 c.94.1.1 (A:1-206) ATP phosphoribosyltransferase (ATP-PRTase, HisG), catalytic domain {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  37  3.RFALTVALPKGRMFREAYEVLKRAGLDLPEV--EGERTLLHGKEGGVALLELRNKDVPIYVDLGIAEIGVVGKDVLLDSGRDLFEPVDLGFGACRLSLIRRPGD--TGPIRRVATKYPNFTARLLKERGWAADVVELSGNIELAAVTGLADAVVDVVQTGATLRAAGLVEVEVLAHSTARLVVNRQALKLKRAVLKPLIQRLRELSGS.... 206
3 -93.700d5m8he_ c.94.1.0 (E:) automated matches {Psychrobacter arcticus [TaxId: 259536]}  ali model 3D-neighbors follow..  50  2..LGLTLALSKGRILEETMPLLRAAGVELLEDPEASRKLIFPTSNPNVRVLILRASDVPTYVEHGAADFGVAGKDVLLEHGANVYELLDLKIAQCKLMTAGVKDAPLPNRRLRIATKYVNVARAYFASQGQQVDVIKLYGSMELAPLVGLGDLIVDVVDTGNTLRANGLEARDHICDVSSRLIVNQVSYKRKFALLEPILDSFKNSIN..... 208
4 -92.600d2vd3a1 c.94.1.0 (A:-1-212) automated matches {Methanobacterium thermoautotrophicum [TaxId: 187420]}  ali model 3D-neighbors follow..  34  3..PKIRIAVPKGRISEPAIRLLENAGVGLKD--TVNRKLFSKTQHPQIEVMFSRAADIPEFVADGAADLGITGYDLIVERGSDVEILEDLKYGRASLVLAAPEDSTIRGRGAVIATEFPGITENYLREHGIDAEVVELTGSTEIAPFIGVADLITDLSSTGTTLRMNHLRVIDTILESSVKLIANRESYATKSGIIEELRTGIRGVIDAE... 214
5 -89.000d1nh8a1 c.94.1.1 (A:1-210) ATP phosphoribosyltransferase (ATP-PRTase, HisG), catalytic domain {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  29  1...MLRVAVPKGALSEPATEILAEAGYRRR---TDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVRERLALGFGSSSFRYAAPAGRTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGRTLSQHDLVAFGEPLCDSEAVLIERAGTQDQTEARDQLVARVQGVVFGQ... 210
6 -88.500d1z7me1 c.94.1.1 (E:1-204) ATP phosphoribosyltransferase (ATP-PRTase, HisG), catalytic domain {Lactococcus lactis [TaxId: 1358]}  ali model 3D-neighbors follow..  44  1...MIKIAITKGRIQKQVTKLLENADYDVEPILNLGRELQIK-TKDDLQIIFGKPNDVITFLEHGIVDIGFVGKDTLDENDFDYYELLYLKIGQCIFALASYPDFSNFQRHKRIASKYPRVTKKYFAQKQEDIEIIKLEGSVELGPVVGLADAIVDIVETGNTLSANGLEVIEKISDISTRMIVNKSSFKFKKDKIIEMVERLED........ 204
7 -87.500d5ub9a_ c.94.1.0 (A:) automated matches {Campylobacter jejuni [TaxId: 195099]}  ali model 3D-neighbors follow..  27  1..TRLRIAIQKGRLSKESIELLSECGVKMH---IHEQSLIAFSTNLPIDILRVRDDDIPGLIFDGVVDLGIIGENVLEENELERKLLKKLDFGYCRLSLALPQENKFQNEGLRIATSYPQLLKRFMKENGINYKNCTLTGSVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALSEKQALVDKIMLRVAGVMQARE.. 221
8 -8.860d2v25a_ c.94.1.0 (A:) automated matches {Campylobacter jejuni [TaxId: 197]}  ali model 3D-neighbors follow..  10  34........................KGFEVDVAKLLAKSIL--GDDKKIKLVAVNAKTRGPLLDNGSVDAVIATFTITPERKRIYNFSEPYYQDAIGLLVLKEKKSLADMKGANIGATTKKAIGEAAKKIGIDVKFSEFPDYPSIKAALKRVDAFSVDKSILLGYVDDKSEILPDSFEPQSYGIVTKKDDPAFAKYVDDFVKEHKNEIDALAKK 228
9 -8.570d2nxoa1 c.94.1.1 (A:5-281) Hypothetical protein SCo4506 {Streptomyces coelicolor [TaxId: 1902]}  ali model 3D-neighbors follow..  10  28..............................................DFELTKDTPEKLSEQLVRGDLDIGPVTLVEFLKNADDLVAFPDIAVGPVMSCVIVSQVPLDRLDGARVALGSTSRTSQLLLSERFGVQPDYYTCPPDLSLMMQEADAAVLIGDAALRANMIDGLDVHDLGAL-AVWAARRDYAEREPVITRKVHEAFLASRN..... 210
10 -8.090d2fyia1 c.94.1.1 (A:88-307) LysR-type regulatory protein Cbl {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  14  2.......NDTSGVLTIATTHTQARYSLP--------KAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVAFPWFR------HHSLLVPHDHPLTQISPLTLESIAKRIDDAFARKGLLADIVLSAQDSDVYVALGLGIGLVAEQSSGEQEEEN-LDTRHLFDANTVWLGLKRG--QLQRNYVWRFLELCNAGLSVEDIK 214
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.