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Query: [L] COG1039 Ribonuclease HIII, from VFDB

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNIVLKLETKERQQLAEKYKSYEQVSKNPYITFFAKVGKTSISVYTSGKVVFQGNEAEKLASDFGHIAQVVPQKQTNLIGTDEVGNGSYFGGLMVTASFVSEENLNFLKEIGVADSKKLTDEKICQIAPKLIDRIPHVALVVEPAKYNEVIASGYNAVSIKVALHNQAIYLLEKQLGHKPENIVIDAFTTEANYKKYVNKEQNHPLTKVTLLTKAEDQFLAVAVSSIISRYLFLENLKKLSKESGFTLPSGAGNLSDKIAAQIIKSQGVDALNQLAKLHFANTQKAIKIAQLLast
1 -73.600d1ekea_ c.55.3.1 (A:) Class II ribonuclease H (RNase HII) {Methanococcus jannaschii [TaxId: 2190]}  ali model 3D-neighbors follow..  23  3.............................................................................IIGIDEAGRGPVLGPMVVCAFAIEKEREEELKKLGVKDSKELTKNKRAYLKKLLENLGYVEKRILEAEEINQLMNS-INLNDIEINAFSKVAKNLIEKLNDDEIEIYIDACSTNTKKFEDSFKDKRNLNIKIIAEHKADAKYPVVSAASIIAKAERDEIIDYYKKIYG---DIGSGYPSDPKTIKFLEDYKHKKLPDIARTHWKTCKRILDKSK. 223
2 -67.900d1i39a_ c.55.3.1 (A:) Class II ribonuclease H (RNase HII) {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  23  2.............................................................................KAGIDEAGKGCVIGPLVVAGVACSDE--DRLRKLGVKDSKKLSQGRREELAEEIRKICRTEVLKVSPENLDERMAA-KTINEILKECYAEIILRL------KPEIAYVDSPDVIPERLSRELEE--ITGLRVVAEHKADEKYPLVAAASIIAKVEREREIERLKEKFG---DFGSGYASDPRTREVLKEWASGRIPSCVRMRWKTVSNLRQK... 200
3 -53.000d2etja1 c.55.3.1 (A:1-221) Class II ribonuclease H (RNase HII) {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  19  4...................................................................DELYKKEFGIVAGVDEAGRGCLAGPVVAAAVVLEKE--------GINDSKQLSPAKRERLLDEIMEKAAVGIGIASPEEIDLY-----NIFNATKLAMNRALENL----SVKPSFVLVDGKGIE-------------LSVPGTCLVKGDQKSKLIGAASIVAKVFRDRLMSEFYPQFSFHKHKGYAT---KEHLNEIRKNGVLPIH---RLSFEPVLELLTDDLL 197
4 -6.930d3bzwa1 c.23.10.9 (A:38-285) Uncharacterized protein BT2961 {Bacteroides thetaiotaomicron [TaxId: 818]}  ali model 3D-neighbors follow..  11  1.CIQHPWQGKKVGYIGDSITDPNCYGDNIKKYWDFLKEWLGITPFVYG---ISGRQWDDVPRQAEKLKKEHGGEVDAILGTNDYNSSVPIGEWQVLSAHGEMKKMVTRKKRTPVMTQDTYRGRINIGITQLKKLFP-QIVLLTPDKNVQPDESYQNGCGEYIDAYVQAIKEAGNIWGIP----VID------FNAVTGMNPMVEEQLIYFYDAGYDRLHPDTKGQERMARTLM-YQLLALPVAF................................................ 248
5 -6.120d2cxxa1 c.37.1.8 (A:2-185) GTP-binding protein engB {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  10  5.............................................................................FAGRSNVGKSTLIYRLTGKKVRRGKKNHKIIDMPGFGFMMGLPKEVQERIKDEIVHFIEDNAKNID--------------------------------------VLVVDGKAAPEIIKRWEKRGEIPIDVEFVAVNKLDKIKNVQEVINFLAEKFEVPLSEIDKVFIPISAKFGDN....................................... 169
6 -5.800d1ej5a_ a.68.1.1 (A:) Wiscott-Aldrich syndrome protein, WASP, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  9..............................................................................VGWDPQNGFDVNN--------LDPDLRSLFSRAGISEAQLTDAETSKLIYDFIED............................................................................................................................................................... 55
7 -5.750d1jx4a2 e.8.1.7 (A:1-240) DinB homolog (DBH) {Sulfolobus solfataricus, DNA polymerase IV [TaxId: 2287]}  ali model 3D-neighbors follow..  16  12.............................................................................YAQVEEVLNPSLKGPVVVCVFSGRFEDSGAVATANY-EARKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQV---------------SSRIMNLLREYSEKIEIASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKTVTVGISKNKVFAKIAADEEVKRLIRELDIADVPGIG----NITAEKLKKLGINKLVDTLSIEFDKLKGMIGEA.. 220
8 -5.740d1ebua1 c.2.1.3 (A:2-150,A:341-359) Homoserine dehydrogenase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  16  9.............................................................................VIGAGVVGSA-------FLDQLLAMKSTITYNLVLLAEAERS---------------------LISKDFSPLNVGSDWKAALAASTTKTLPLDDLIAHLKTSPKVILVDNTSSAYIAGFYTKFVEN--GISIATPNKK-------AFSSDLATWKALFSNKPTNGFVYHEATVGAGLXAAVTAAGVLGD.......................... 161
9 -5.720d1xp2b1 d.65.1.5 (B:2-149) L-alanyl-D-glutamate peptidase Ply {Listeria phage A500 [TaxId: 40522]}  ali model 3D-neighbors follow..  11  1...........................................................................................................................................MALTEAWLIEKANRKLNAGGMYKITSDKTRNVIKKMAKEGIYLCVAQGYRSTAEQNALYAQGRTKPGAIVTNAKGGQSNHNYGVAVDLCSTTSRWKKVVAAMKAEGFKWGGDWKSFKDYPHFELCDAVSGEKIPA.................. 147
10 -5.580d3gv7b1 e.8.1.7 (B:26-299) DNA polymerase iota {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  14.............................................................................YAQVEMISNPELKDPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKEREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSDELSAVTVSGHVYNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQLG--TGCAGVASNKLLAKLV-ESCQHLIHSLNHIKEIPGIGYKTAKC----LEALGINSVRDLQTFSPKILEKELGIS.. 251

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Lesley SA, Kuhn P, Godzik A., Deacon AM, Mathews I, Kreusch A, Spraggon G, Klock HE, McMullan D, Shin T, Vincent J, Robb A, Brinen LS, Miller MD, McPhillips TM, Miller MA, Scheibe D, Canaves JM, Guda C, Jaroszewski L, Selby TL, Elsliger MA, Wooley J, Taylor SS, Hodgson KO, Wilson IA, Schultz PG, Stevens RC. Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11664-9. Epub 2002 Aug 22.