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Query: [S] COG4121 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFIMSSISHAQLGWNDAGTPVSDQFDDVYFSNVNGLAETRYVFLEQNHLPQRWHNDDQRRFVIAETGFGTGLNFLAVWQAFVAFREANPDAKLKELHFISFEKYPLSKSDLIQAHQAWPELAQFAQKLHKHYPLAIPECQRIVLNDGLVTLDLWFGDIKDCLPKVATQEQGLVDAWFLDGFAPSKNPEMWNQNLFAGMAKLAKHGCTCATFTSAGFVRRGLIDAGFAMKKVKGFGTKREMIAGSLSEKVPYTNIAPEFRFEATHGLQEVAIIGGGIASATLATTLALast
1 -14.900d3orha_ c.66.1.16 (A:) Guanidinoacetate methyltransferase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  12  7.....................GENCSPAWGAAPAAYAADTHLRILGKPVMERWETPYMHALAVLEVGFGMAIAASKVQEAPID-------------EHWIIECNDGVFQRLRDWAPRQTH-----------------------------KVIPLKGLWEDVAPTL---PDGHFDGILYDTYPLSEETTHQFNFIKNHAFRLLKPGGVLTYCNLTSTQVPALLEAGFRRENIR...................................................... 202
2 -12.700d2a14a1 c.66.1.15 (A:5-261) Indolethylamine N-methyltransferase, INMT {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  11  3................GGDEYQKHFLTYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACDSFQ-------------DITLSDFTDRNREELEKWLKKEPGAYDWTPKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLG-NPLAPAVLPLADCVLMECACCSLDA----RAALCNLASLLKPGGHLVTTVTLREVEQAVLDAGFDIEQL....................................................... 231
3 -10.300d2g72a_ c.66.1.15 (A:) Phenylethanolamine N-methyltransferase, PNMTase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  11  16.....................PRAYLRNNYAPPRGDLCNPNGVGP-RCLAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFE-------------DITMTDFLEVNRQELGRWLQEEPNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADAFCLEAVSPDLAS----QRALDHITTLLRPGGHLVVPVSEEEVREALVRSGYKVRDLR...................................................... 238
4 -9.410d2gpya_ c.66.1.0 (A:) automated matches {Bacillus halodurans [TaxId: 272558]}  ali model 3D-neighbors follow..  16  53.............................................................RILEIGTAIGYSAIRMAQALPE-------------TIVSIERDERRYEEAHKHVKALGLES---------------------------RIELLFGDALQLGEKL--ELYPLFDVLFIDAAKGQ-------RRFFDMYSPMVRPGGLI--------LSDNVLFRGLVAETDIEHKRHKQLATKIDTYNQWLLEHPQY--------DTRIFPVGDGIA......... 205
5 -9.180d2oyra1 c.66.1.55 (A:1-250) Hypothetical protein YhiQ {Shigella flexneri [TaxId: 623]}  ali model 3D-neighbors follow..  11  74............................................RGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCR--------------VRMLERNPVVAALLDDGLARGYADAEIGGWLQER-------------------LQLIHASSLTALTDI----TPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPAVVKRPDYAPPLA........................................................... 227
6 -8.710d3ntva_ c.66.1.0 (A:) automated matches {Staphylococcus aureus [TaxId: 196620]}  ali model 3D-neighbors follow..  13  54.............................................................NILEIGTAIGYSSMQFASISDD-------------HVTTIERNETMIQYAKQNLATYHFEN---------------------------QVRIIEGNALEQFENVN---DKVYDMIFIDAAKAQ-------KKFFEIYTPLLKHQGLV--------ITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNE-------WLIKQPGYTTNFLNIDDGLAISIKG.... 211
7 -8.690d4pcaa1 c.66.1.0 (A:1-218) automated matches {Anaplasma phagocytophilum [TaxId: 1217107]}  ali model 3D-neighbors follow..  14  59.............................................................SIVEVGTCVGFSAICMAHALPSKG-----------HIYTIEKDYENVVTANQNIVNCKLED---------------------------KITVLHGEALAQLNTL--KEMAPFDMIFIDANKSS-------LAYLNWAKMYIRKGGLI--------VADNTFLFGSVFDEHPTEKVSSNAHASMRAFNDELANKEKY--------LSTIIPTSEGMM......... 212
8 -8.220d5p9va_ c.66.1.1 (A:) Catechol O-methyltransferase, COMT {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  14  59.............................................................LVLELGAYCGYSAVRMARLLQPGA-----------RLLTMEINPDCAAITQQM---------------------------LNFAGLQDKVTILNGASQDLIPQLKKKYDDTLDMVFLDHWKDRYLPDT-----LLEKCGLLRKGTVLLA............................................................................ 166
9 -8.200d2pwya_ c.66.1.0 (A:) automated matches {Thermus thermophilus [TaxId: 262724]}  ali model 3D-neighbors follow..  16  92.............................................................RVLEAGTGSGGLTLFLARAVGEKG-----------LVESYEARPHHLAQAERNVRAFWQVE---------------------------NVRFHLGKLEEAELE-----EAAYDGVALDLMEP---------KVLEKAALALKPDRFLVAYLPN-ELVRAAEAHPFRLERV....................................................... 214
10 -8.140d1an9a1 c.4.1.2 (A:1-194,A:288-340) D-aminoacid oxidase, N-terminal domain {Pig (Sus scrofa) [TaxId: 9823]}  ali model 3D-neighbors follow..  26  2...........................................................................................................................................................................................................................................................................RVVVIGAGVIGLSTALCIH 20

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 6 1 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Godzik A., Rychlewski L. A support vector machine approach to the identification of phosphorylation sites. Cell Mol Biol Lett. 2005;10(1):73-89.