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Query: [S] KOG2632 Rhomboid family proteins, from VFDB

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRPNIVTEAGVQTRVGQWWNAIPFLTSSVVVVCGVIYLICLLTGYDTFYEVCFLPSAIISRFQVYRFYTAIIFHGSLLHVLFNMMALVPMGSELERIMGSVRLLYLTVLLATTNAVLHLLIASLAGYNPFYQYDHLMNECAIGFSGILFSMIVIETSLSGVTSRSVFGLFNVPAKLYPWILLIVFQLLMTNVSLLGHLCGILSGFSYSYGLFNFLMPGSSFFTTIESASWMLIVTHPVSMSSSSLASLGDPSSLCVLAGILPAIFPLILHKTQHPGNAWRSLSSWLPQREASNQSSEDSRFPGRGRTLSTARDPTAPAGETDPNLHARLLEDSSSPDRLSDATVNTVADSRQAPIANAAVLPQSQGRVAASEEQIQKLVAMGFDRTQVEVALAAADDDLTVAVEILMSQQVLast
1 -59.000d2xova_ f.51.1.1 (A:) GlpG {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  19  1...................ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFS---------------GPWFGGLSGVVYALMGYVWLRGERDPQSGIYL-GLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVD........................................................................................................................................................................................................ 178
2 -58.100d2nr9a1 f.51.1.1 (A:4-192) GlpG homolog HI0618 {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  18  1.................FLAQQGKITLILTALCVLIYIAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGYVQNYVS---------------GPAFFGLSGVVYAVLGYVFIRDKLNHHLFLPEGFFTMLLVGIALGFISPLFGVEMGNAAHISGLIVGLIWGFIDSKLRKNSLE............................................................................................................................................................................................... 189
3 -22.300d1vg5a1 a.5.2.1 (A:8-67) Rhomboid family protein At3g58460 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  100  1.............................................................................................................................................................................................................................................................................................................................................................SRQAPIANAAVLPQSQGRVAASEEQIQKLVAMGFDRTQVEVALAAADDDLTVAVEILMSQ.. 60
4 -20.700d1vega1 a.5.2.1 (A:8-77) NEDD8 ultimate buster-1 (Nub1) {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  27  8....................................................................................................................................................................................................................................................................................................................................................................QDADPENNSRQASPSQESINQLVYMGFDTVVAEAALRVFGGNVQLAAQTLAHHG. 61
5 -18.400d1wiva1 a.5.2.1 (A:8-67) Ubiquitin isopeptidase T {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  18  6..................................................................................................................................................................................................................................................................................................................................................................DDPDIDAPISHQTSDIDQSSVDTLLSFGFAEDVARKALKASGGDIEKATDWVFNN.. 60
6 -17.100d1wgna1 a.5.2.1 (A:8-57) Ubiquitin-associated protein 1, UBAP1 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  1.......................................................................................................................................................................................................................................................................................................................................................................AYSELQMLSPSERQCVETVVNMGYSYECVLRAMKKKGENIEQILDYLFAH.. 50
7 -16.000d1veka1 a.5.2.1 (A:8-78) Ubiquitin isopeptidase T {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  19  1.............................................................................................................................................................................................................................................................................................................................................................GEELLPDGVPEEVMESAQPVANEEIVAQLVSMGFSQLHCQKAAINTNAGVEEAMNWLLSHM. 62
8 -15.800d2g3qa1 a.5.2.1 (A:1339-1381) Endocytic protein Ede1, YBL047C {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  23  1...............................................................................................................................................................................................................................................................................................................................................................................TTPKSLAVEELSGMGFTEEEAHNALEKCNWDLEAATNFLLDSA. 43
9 -15.600d3k9oa2 a.5.2.1 (A:157-200) Ubiquitin-conjugating enzyme E2-25 kDa, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  43  6..................................................................................................................................................................................................................................................................................................................................................................................YTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN.. 44
10 -15.500d1wjia1 a.5.2.1 (A:8-57) Tudor domain containing protein 3, TDRD3 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  1.................................................................................................................................................................................................................................................................................................................................................................................VDEKALKHITEMGFSKEASRQALMDNGNNLEAALNVLLTSN. 41
11 -15.500d1z96a1 a.5.2.1 (A:295-332) UBA-domain protein mud1 {Fission yeast (Schizosaccharomyces pombe) [TaxId: 4896]}  ali model 3D-neighbors follow..  42  1.................................................................................................................................................................................................................................................................................................................................................................................GLNSKIAQLVSMGFDPLEAAQALDAANGDLDVAASFLL.... 38
12 -15.400d5xbob_ a.5.2.1 (B:) DNA repair protein Hhr23a {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  29  6................................................................................................................................................................................................................................................................................................................................................................................SEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTG.. 46
13 -15.300d2dnaa1 a.5.2.1 (A:8-61) Ubiquilin-like protein Ubqlnl {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  30  3.........................................................................................................................................................................................................................................................................................................................................................................HSLQAPEVRFSKEMECLQAMGFNYNANLQALIATDGDTNAAIYKLKSSQ. 52
14 -15.000d2daka1 a.5.2.0 (A:8-57) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  35  2..................................................................................................................................................................................................................................................................................................................................................................................PEDCVTTIVSMGFSRDQALKALRATNNSLERAVDWIFSH.. 40
15 -14.800d1dv0a_ a.5.2.1 (A:) DNA repair protein Hhr23a {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  33  2..................................................................................................................................................................................................................................................................................................................................................................................EKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQ.. 40
16 -14.600d2cpwa1 a.5.2.1 (A:8-58) Cbl-interacting protein p70, STS1 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  25  3.........................................................................................................................................................................................................................................................................................................................................................................RQQRPGTIKHGSALDVLLSMGFPRARAQKALASTGRSVQTACDWLFSH.. 51
17 -14.000d2daga1 a.5.2.0 (A:8-68) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  26  1.................................................................................................................................................................................................................................................................................................................................................................................LDESVIIQLVEMGFPMDACRKAVYYTNSGAEAAMNWVMSHM. 42
18 -13.100d2dena_ a.5.2.0 (A:) automated matches {Streptococcus sp. [TaxId: 1306]}  ali model 3D-neighbors follow..  30  2................................................................................................................................................................................................................................................................................................................................................................................SQWQPQLQQLRDMGIDDELSLRALQATGGDIQAALELIFA... 42
19 -13.000d1wj7a1 a.5.2.1 (A:8-98) Ubiquitin-associated protein 2-like Ubap2l {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  15  1...................................................................................................................................................................................................................................................................................................................................................NQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDIGKNQDECVIALHDCNGDVNRAINVLLEGNP 73
20 -12.500d2crna1 a.5.2.1 (A:8-58) Suppressor of T-cell receptor signaling 2 (STS-2) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  29  1.................................................................................................................................................................................................................................................................................................................................................................................SSPSLLEPLLAMGFPVHTALKALAATGRTAEEALAWLHDHC. 42
21 -11.500d4un2b1 a.5.2.1 (B:328-369) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  28  3................................................................................................................................................................................................................................................................................................................................................................................ERYEHQLRQLNDMGFDFDRNVAALRRSGGSVQGALDSLL.... 42
22 -10.500d2mj5b1 a.5.2.1 (B:913-959) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  3................................................................................................................................................................................................................................................................................................................................................................................DQTAALMAHLFEMGFDRQLNLRLLKKHNYNILQVVTELLQLN. 45
23 -9.590d1vdla1 a.5.2.1 (A:8-74) Ubiquitin carboxyl-terminal hydrolase 25 {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  18  2................................................................................................................................................................................................................................................................................................................................................................TVEQNVLQQSAAQKHQQTFLNQLREIT--GINDAQIQQALKDSNGNLELAVAFLTAKNA 59
24 -9.440d1ufza1 a.5.9.1 (A:8-77) HBS1-like protein {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  10  1.....................................................................................................................................................................................................................................................................................................................................................EYGYEDLRESSNSLLNHQLSEIDQARLYSCLDHMREVLGDAVPDDILTEAILKHKFDVQKALSVVLEQD. 69
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 3 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Plewczynski D, Tkacz A, Wyrwicz LS, Godzik A, Kloczkowski A, Rychlewski L. Support-vector-machine classification of linear functional motifs in proteins. J Mol Model 2006 Aug;12(4):453-61. Epub 2005 Dec 10.