current user: public
If you have questions about the server, please let us know.

Query: [F] COG0208 Ribonucleotide reductase, beta subunit, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .
# Score Template Links and tools%idFirst MLRQEAKRMKATMAYSTFTQKKNDQLKEPMFLGQPVNVARYDQQKYEIFEKLIEKQLSFFWRPEEVDVSSDRIDYGKLPDHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPAVVFDDIVENEHIIKRAKDIAHYYDDLIELTNDYHRYGEGQHQINGETITVSLKELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIKLIARDEALHLTGTQHMLNLLRNGMDDFTFLQVAEECKQESFDLFKEAAEQEKEWAEYLFKDGSMIGLNKDILCQYVEYITNIRMQAVGLEPAYPAATNNPIPWINAWLSSDNVQVAPQEAEISSYLVGQIDNEVSADDFEGFELLast
1 -101.000[F] COG0208 Ribonucleotide reductase, beta subunit  ali  100  1MLRQEAKRMKATMAYSTFTQKKNDQLKEPMFLGQPVNVARYDQQKYEIFEKLIEKQLSFFWRPEEVDVSSDRIDYGKLPDHEKHIFISNLKYQTLLDSIQGRSPNVALLPLVSLPELETWIETWSFSETIHSRSYTHIIRNIVNDPAVVFDDIVENEHIIKRAKDIAHYYDDLIELTNDYHRYGEGQHQINGETITVSLKELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIKLIARDEALHLTGTQHMLNLLRNGMDDFTFLQVAEECKQESFDLFKEAAEQEKEWAEYLFKDGSMIGLNKDILCQYVEYITNIRMQAVGLEPAYPAATNNPIPWINAWLSSDNVQVAPQEAEISSYLVGQIDNEVSADDFEGFEL 389
2 -79.900[F] KOG1567 Ribonucleotide reductase, beta subunit  ali follow..  22  6..RPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKK--------------------------KADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSE-----------ERVREIIVDAVKIEQEFLTEALPVG-LIGMNCILMKQYIEFVADRLLVELGFSKVFQA--ENPFDFMENI--SLEGKTNFFEKRVSEYQRFAVMAETTDNVFTDADF 351
3 -18.600[S] COG3396 Uncharacterized conserved protein  ali follow..  7  9...............................................................QRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIVGMLPEGNWITR-APTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRMKYSSI------------------------------------NYPTLSWADIGVIGWLVDGA------IVNQVALCRTSYGPYARAMVKICKEESFHQRQGFEACMALAQGSEAQ-----KQMLQDAINRFWWPALMMDNSPNSARSLTWKIKRFTNDELRQRFVDNTVPQVEMLGMT...................................................... 239
4 -16.600[S] COG2833 Uncharacterized protein conserved in bacteria  ali follow..  10  32......................................................RETASRWFARALSVRSPLRMLKKRSLNTEHGRIALMHALAHIELNAIDLALDIVARFAVKPSFFDGWMKVADDEARHFTLLRNRLKSLGADYGDM----------------------------------------AHDGLWQSAHQTRNDLEARLAVVPLILEARGLDVTPSLLEKMIETG--HETAAILNIIYNDEKTHVAVGAKWFRFFCARNRIDPAARFRELVRANFRGELKPPFNELAR---------AEAGLTPSFYRSLSPVSI................................................................ 275
5 -9.320[S] COG1633 Uncharacterized conserved protein  ali follow..  12  13................................................................................RNLKGIEEAIALAIDREK--AREFYLQQAGLMENPKFKELYEELAAEEMKHLGYLENYRDKKELPEISTEVPSGQSFSPEFDAS-------------------------------RTKVGEITLGDAGILLAAMRHE----RKSEDFYSEMAKRVEDETQKKFFEMLSRYERGHYEVIDSYLEYITQF......................................................................................................................... 164
6 -9.030[R] COG3687 Predicted metal-dependent hydrolase  ali follow..  11  77.VNAVATFSEGAAMVSVDDRATGPHSSESRAADHERLVLEPRDVEFDW------TNLPFHYVPNEPMATHVLNVLHMLLPAGEEFFVRVFK---------------KTLPLIKDDQLRLDVQGFIGQEAMHSQAHSGVVDHFDAQGVDV-------TAFTNQIRWLFEKLLGESPRRSPRR--------------------QYSWLLEQVSFIAAIEHYTAVMGEWIL-QLDAVGADPVMLDMLRWHGAEEVEHKAVAFDTMKHL............................................................................................................................ 294
7 -7.740[P] COG3546 Mn-containing catalase  ali follow..  12  11................................................................TVRVSEPNPGLANL-------LLEQFGGPQGELAAACRYFTQGLS--DDDAGRREMLMDIATEELSHLEIIGSLVGMLNKGAK-----GELAEGTENEAELYRSLTQNGNDSHITSLLYGGGPALTNSGGVPWTAADTIGEVTADLRSNIAAE----ARAKIIYERLINLTDDPGVKDTLSFLMTREVAHQLSFEKALYSIRNNFPPGKLPPVEQYTD........................................................................................................... 212
8 -7.560[S] COG3461 Uncharacterized conserved protein  ali follow..  8  1...................................................................MADQYHEPVSELTGKDRDFVRALNSLK--EEIEAVAWYHQRVVTTKDETVRKILEHNRDEEMEHAAMLLEWLRRNMPGWDEALRT............................................................................................................................................................................................................................................. 83
9 -6.490[S] COG3685 Uncharacterized protein conserved in bacteria  ali follow..  9  2...............................................................................ATANEHLVAWLRDAHAMEEQAITMLTSQSSRLENYPELKTRIDRHLQETKDQAAMLERCLERLDGGTSSIKDISGKIVAFGQGL-----------------------------------GLFVSDEVVKGTLASYTFEHMEI-ASYRILIAAAEQAGDQETKRVCESILQQEIAMAEWLAQNAGEITRK......................................................................................................................... 155
10 -6.470[R] COG2406 Protein distantly related to bacterial ferritins  ali follow..  8  1...................................................................MARVAREMVEKAGVDVDKLLELLIKNAAAELTTYYYYTRANLIGLEGETIKEIAEVARIEDRNHFEALVPRIYELGGKLPDCMKEFHDLSACPP------------------------------------ARLPDKPTVQEILRVLVAAERCAV-KGYTEICNMTAGK--HRTYELSLAILNEEIEHESWFSEFLGE............................................................................................................................. 161
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 4 0   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Tolerating some redundancy significantly speeds up clustering of large protein databases. Bioinformatics. 2002 Jan;18(1):77-82.