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Query: [J] COG0242 N-formylmethionyl-tRNA deformylase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEVLast
1 -102.000[J] COG0242 N-formylmethionyl-tRNA deformylase  ali  100  1MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEV 183
2 -11.400[R] COG4740 Predicted metalloprotease  ali follow..  24  55.............................................IKEKVTRFDEDEMIGRTLEIV---------------------YLFLNPRIIS---EEGTVYRFEKC---SRNERELVSRPYRVVVDGIRLKRLEKPLRFTGSGAYGVAHEMEHLEG...................... 158
3 -5.870[F] KOG3721 Mitochondrial endonuclease  ali follow..  124..........PDITFPQKFLSQNTDYKCSGFDRGHLAAAGNHRKSQLAVDQTFYLSN----MSPQVGRGFN-LEMHCRRVAKKMINSYIITGPLYLPKLEGDKYQVIGDNNVAVPTHFFKVAVTPGKFELESYILPNAVIEDTVEISKFHVPLDAVERSAGLEIFARLDPKSIVKENGA.... 301
4 -5.800[R] COG0319 Predicted metal-dependent hydrolase  ali follow..  17  47...........................................................................................EAESHALNLNYRGKDKPTNVLSFPMDLLGDL-----ICRQVVEREAIEQNKPLQAHWAHMVVHGSLHLLG---YDHIEDDEAEEMESLETEI 139
5 -5.680[F] COG1864 DNA/RNA endonuclease G, NUC1  ali follow..  150..............................................QAMDDTFYLSN----MCPQVGEGFN-LEYFCRGLTKKYKSVRIVTGPLYLPKKDPNYEVIGNPPSIAVPTHFFKLIVAEADIAVAAFVLPNEPISNETKLTDFEVPIDALERSTGLELLQKVPPSKKKALCKEVN.. 300
6 -5.650[S] COG3091 Uncharacterized protein conserved in bacteria  ali follow..  13  1..........................................................................................MSTLRIPIALQQAVMQCLRHYLQLANQHLGTAYPEPKVNYHEIRLNPVLLLENKQPFIDEVVPHELAHL........................ 83
7 -5.380[S] COG5591 Uncharacterized conserved protein  ali follow..  11  20..........................................................................................LVQLSNEFTWKISEMEIDDGCYE----------------LHVTDENGNVLKVKVDPETMKVVAGKVKR......................... 71
8 -5.110[T] COG5212 Low-affinity cAMP phosphodiesterase  ali follow..  1.............................................MHAALEIKEAEFQTDQVVGLVENSFTLYSLGQNGGPLESCCSSHLISD---GAFQEIISLDGGSHLSALVELIQSKHLSVDSWSSITKYDN-KAWHLSEQRIKTFLITHHLDHIYGAVIN.................. 126
9 -5.020[O] COG0501 Zn-dependent protease with chaperone function  ali follow..  19  60...............................REVTPAESPNLHRIVDGLALK------ANIPKPKVYVV-----------------DSGMPNAFATGRNPQHAAVAVTTGILN---------------LLSYEEIEG-------------VLAHELAHV........................ 136
10 -4.960[R] COG4783 Putative Zn-dependent protease, contains TPR repeats  ali follow..  11  45................DQEMAMGDFYVRQMRASAPLIYDPLLTQYINTLGNRLVA------NANSVRTPFHFYLVNNDQ-----------IN------------------AFAFFGGN---------VVLH----SALFRYTDNESELASVLAHEISHVTQRHLARAMEEQQRLAPLTWVGVL 163

FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.