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Query: [C] COG0247 Fe-S oxidoreductase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSGFLIANALLFLIVTAYAVYLFVYLVKTRLAYIKLGQKEQFDQRFKERLHAIWVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFIIKGLAPGRNLSLGPVYPAFTFFQEIVTFLILIAVGWAFYRRYIEKLVRLKRGFKAGLVLIFIGGLMLTVLLGNGMNLIWHEHGLSWSEPIASGIAFMLSGVGKTGAAVIFYIAWWIHLLFLLSFLVYVPQSKHAHLIAGPANVFFNRMESAGKLEKIDFTDETKESYGAGKIEDFRQSQLLDLYACVECGRCTNMCPATGTGKMLSPMDLILRLRDHLTEKGAAVTSRSPWVPAAAFRHTRGNQLAAASAGSGSQEAAAALDYNPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKIIDLRRYLVLTEGKMDSDAQRAMTSIERQGNPWGLNRKERENWRDEAPDAEIPTVKEMKKEGKEFEYLFWVGSMGSYDNRSQKIAISFAKLLNHAGVSFAILGNKEKNSGDTPRRLGNEFLFQELAEKNISEFEKNDVKKIVTIDPHAYNLFKNEYPDFGFEGEVYHHTEVLAELVKNGKLRPQHPLHETITFHDSCYLGRYNEVYDPPREILKAIPGVQLVEMERSRETGMCCGAGGGLMWMEEETGNRINVARTEQALAVNPSVISSGCPYCLTMLGDGTKAKEAEDQVKTYDVVELLAQSVLGADLKMGEKQLast
1 -162.000[C] COG0247 Fe-S oxidoreductase  ali  100  1MSGFLIANALLFLIVTAYAVYLFVYLVKTRLAYIKLGQKEQFDQRFKERLHAIWVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFIIKGLAPGRNLSLGPVYPAFTFFQEIVTFLILIAVGWAFYRRYIEKLVRLKRGFKAGLVLIFIGGLMLTVLLGNGMNLIWHEHGLSWSEPIASGIAFMLSGVGKTGAAVIFYIAWWIHLLFLLSFLVYVPQSKHAHLIAGPANVFFNRMESAGKLEKIDFTDETKESYGAGKIEDFRQSQLLDLYACVECGRCTNMCPATGTGKMLSPMDLILRLRDHLTEKGAAVTSRSPWVPAAAFRHTRGNQLAAASAGSGSQEAAAALDYNPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKIIDLRRYLVLTEGKMDSDAQRAMTSIERQGNPWGLNRKERENWRDEAPDAEIPTVKEMKKEGKEFEYLFWVGSMGSYDNRSQKIAISFAKLLNHAGVSFAILGNKEKNSGDTPRRLGNEFLFQELAEKNISEFEKNDVKKIVTIDPHAYNLFKNEYPDFGFEGEVYHHTEVLAELVKNGKLRPQHPLHETITFHDSCYLGRYNEVYDPPREILKAIPGVQLVEMERSRETGMCCGAGGGLMWMEEETGNRINVARTEQALAVNPSVISSGCPYCLTMLGDGTKAKEAEDQVKTYDVVELLAQSVLGADLKMGEKQ 705
2 -39.300[C] COG2048 Heterodisulfide reductase, subunit B  ali follow..  14  12.................................................................................................................................................................................................................................................................................................................................................................................................................................................................MGGIGKKVAYYPGC--SLEGAARAYDVSTRIVAKELGLELDYL-EDYNCCGAMETKNVSFWGTMLLNARNMSLARRQGHNVIVAPCNGCSFSLQRVEYFLDNIPHTYHILEWFYHEAGPEKVKEKTKRGLKVASYYGCLYTRPHFYARTYSHLAPEAAGATSVEIEPMH----TQCCGGPHSLSDEEVSEKFVMMILQTAKRNGADIIATECPLCHASLEMYRLKGVPDVDVPAAYFTQLLGLAFGYSVNDVKLKD 316
3 -37.200[C] COG1150 Heterodisulfide reductase, subunit C  ali follow..  20  9....................................................................................................................................................................................................................................................IREEDLNPDFLEELSELVEPVFEEEEVLSVQACYQCGTCTGSCPSGRRT-SYRTRLIMRKLQLGLVD-------------------------------------------------EVIKSDELWMCTTCYTCYERCPRGVKIVDAVKAARNLAA-KKGYMAKAHRMVAMFVIKTGHAVPINDEIREVRKN---IGLDEVPPTTHRYEEALEEVQKLVKINEFDKLIGYDWEE-GDLVD.............................................................................................................................................................................................................................. 192
4 -26.300[C] COG2181 Nitrate reductase gamma subunit  ali follow..  14  1.....MSGQILWGIMPYIVLTIFIGGHIYRYQHDQFGWTAK------------------SSELLEKKKLAAGSTLFHWGLLCVVGGHVMGILEGVYASLGISEHMYHKMAIGAGLPAGIAACTGLVILTYRRLFDKRIRKTSSPSDILTLLLLLFMMLSGVAATFLNID--SKGFDYRTTVGPWFREIVLFRPDASLMESVPLWFKFHIVIGYVVFILWPFTRLVHVFSLPLKYLTRSYV................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 217
5 -24.100[C] KOG3049 Succinate dehydrogenase, Fe-S protein subunit  ali follow..  15  39............................................................................................................................IKKFAIYRWDPDKAGDKPHMQTYEVDLNKCGPMVLDALIKIKNEVDSTLTFRRSCREGICGS----AMNINGGNTLACTRRIDTNLNKVSKIYPLPHMYVIKDLVPDLSNFYAQYKSIEPY--LKKKDESQEGKQQYLQSIEEREKLDGLYECILCACCSTSCPSYWWNGDLGPAVLMQAYRWMIDSRDD---------------------------------------FTEERLAKLQDPFSLYRCHTIMNCTRTCPKGLNPGKAIAEIKKMMATYKEKKAS.......................................................................................................................................................................................................................................................................................................... 279
6 -22.400[C] COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit  ali follow..  14  82.............................................................................................................................................................................................EGICGSCAMNIDGTNTLACTKGMEEIKGTVKVYPLPHMVVKDLVPDLSNFYAQHRSIEPWLKTVSPTPAKEWKQSHEDRLKLDGLYECILCACCSTSCPSYWWNGDLGPAVLLQAYRWLIDSRDE---------------------------------------ATGERLDNLEDPFRLYRCHTIMNCAQACPKGLNPAKAIAEIKKMMVERR............................................................................................................................................................................................................................................................................................................... 258
7 -16.700[C] COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit  ali follow..  12  405................................................................................................................................................................................................................................................................................LASECTDCGWCQRVCPNS-----LPVMDAVKKAADGDLSKLEEM-------------------------------------------------AIEELCYTCGRCEQECERNIPIVSMVTKAGERRVKDEKYRIRAGRGPAQDVEIRRVGAPIVLGDIPGVVAFVGCSNYPEGGKDVALLERNYIVVTTGCGAM--SIGEYRDEDGQTLYEKYGGQFDALVNMGSCVSNAHVSGAAIKIANIFAQKPLEGNFEEIADYILNRVGACGVAWG-AYSQKAAAIATGVNRWGIPVVLGPHGSKYRRLFLGRADDEEKWKLKDLRTGEVIDGEPAPEH----LLYAAENREEATVMIAKLCIRPTDTPKGRQMKLSNYIDLHRKYLGTIP----------DDIDRFIRTEKDIPIVYKRDVM-KILEEKNWKPRE.. 770
8 -13.500[C] COG1146 Ferredoxin  ali follow..  14  31.....................................................................................................................................................................................................................................................................DRKEIEWYPTIDYDKCVTCGICFVTCGRRVFDFDKKEGKVIVARPYN-------------------------------------------------------------CMVACQTCMNLCPTGA--ISFPDASYIKKLVAQNKIVKKAFEIIKPLLAEDH............................................................................................................................................................................................................................................................................................ 127
9 -11.900[C] COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit  ali follow..  25  45............................................................................................................................................................................................................................................................................MPVIDESKCVKCYICWKFCPEPAIYIKEDGFVAIDYDY----------------------------------------------------------------CKGCGICANECPTK................................................................................................................................................................................................................................................................................................................................. 96
10 -11.800[C] COG1142 Fe-S-cluster-containing hydrogenase components 2  ali follow..  20  1.........................................................................................................................................................................................................................................................................MNRFVIADSTLCIGCHTCEAACSETHR---QHGLQSMPRLRVMLNEKESAPQLCHHCAPCAVVCPVNAITRVDGAVQLNES-----------------------LCVSCKLCGIACPFGAIEFS............................................................................................................................................................................................................................................................................................................................ 100
11 -10.800[R] COG3383 Uncharacterized anaerobic dehydrogenase  ali follow..  11  143...............................................................................................................................................................................................................................................................................YDPDQCILCGRCVEACQQVQVNETLSIDWERSQPRVIWDDDRPANLSCVSCGLCATVCPCNALMEKSMLGQAGFMTGLDEDMLEPMIDMVKKVEPNYQT-TVCTFCGVGCTFEVWTKDRKIPVNKFATCVKGKFGWDFKRITTPLIREGNEF-----VPASWEDAIHL--VATKLREIQAKYGNDSIGFISSSKTTNEENYLMQKLARQVFETNNID-RTVGIEDIESAGLVIIVGSPADGHPVLASRIKRAQKTRGQKLIVSDLRKHEMAEDLFIHPKQGTDFVWLTAVAKYIIDQN-------------WHDQVFMENRISNVADYLAFLEPFTLEYAEKE---------TG---------------LPAETLKLV----AEMIHEADGTAVCWGMGVTQNIAGSHTSSAIANLLLVTGNFGRHGA...... 579
12 -10.700[C] COG2878 Predicted NADH:ubiquinone oxidoreductase, subunit RnfB  ali follow..  11  33.......................................................................................................................................................................................................................................................................DDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIANCIGCTKCIQACPVDAIVGATRAMH-------------------TVMSD---LCTGCNLCVDPCPTHC................................................................................................................................................................................................................................................................................................................................ 161
13 -10.000[C] COG0437 Fe-S-cluster-containing hydrogenase components 1  ali follow..  11  4..........................................................................................................................................................................................................................................................................QYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAGGDWQEDNGVISCNHCDDCTKVCPSGAMHKREDGFVVVDED----------------------VCIGCRYCHMACPYGAPQYNAEKGHMTKCDVAEGKQPICVESCPLRALEFGP............................................................................................................................................................................................................................................................................................ 154
14 -9.150[C] COG1140 Nitrate reductase beta subunit  ali follow..  183...................................................................................................................................................................................................................................................................................LCEHCLNCVATCPSGAIYKREEDGIVLIDQD-----------KCRGWRMCITGCPYKKIYFNWK-------------------------SGKSEKCIFC-VCSETCVGRIRYLGVLLYDADAIRQLEVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMAMEWKLALPLHPEYRTLPMVWY-LSPIQSAADAGELGSNGILPDVESLRIPVQYLAN--------LLTAGDTKPVLRALKRMLAMRHYKRAETV----------------------DGKVDTRALEEVLTEAQAQEMYRYLAIANYED--------------RFV---VPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT................................................. 508

FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 5 6 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.