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Query: [R] COG0319 Predicted metal-dependent hydrolase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSIELDLQLAVENEHGLPSEAEFALWLTRTITPFQAQAEVTVRIVDEAESHALNLNYRGKDKPTNVLSFPFEAPSGMEMDLLGDLVICRQVVEREAIEQNKPLQAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETEIMQEMGFTDPYLAEKELast
1 -85.500[R] COG0319 Predicted metal-dependent hydrolase  ali  100  1MSIELDLQLAVENEHGLPSEAEFALWLTRTITPFQAQAEVTVRIVDEAESHALNLNYRGKDKPTNVLSFPFEAPSGMEMDLLGDLVICRQVVEREAIEQNKPLQAHWAHMVVHGSLHLLGYDHIEDDEAEEMESLETEIMQEMGFTDPYLAEKE 154
2 -9.230[S] COG3824 Uncharacterized protein conserved in bacteria  ali follow..  14  77.................PSMEEMEFLALEAYAHLPEDGEIVIQIAEFPTDEIMDDL--SLETPFDLLGLIAERWNPQTGEGPNRITLYRRAMLDYWAENEETLGDIVTHVLIHEIGHHFGLSDDDMEKIE........................ 197
3 -8.440[O] COG5549 Predicted Zn-dependent protease  ali follow..  12  85FPVTVAVDYPPGLTPGSAAQKRYYTWQQAIKTAIADQEFFPLTIVENTTEADITIFYREPPLPRIVDPETGLVSFGRARTAQANYEFYWTDTSPPQLRHRMAIPLSLQGTARHELGHALGIWGHSDHKEDALYPAQTADVPAISPRD-YQQPTR 252
4 -7.380[R] COG1913 Predicted Zn-dependent proteases  ali follow..  13  1MMGMIIIVPIGE-------PGDVLAFLQNSLSGFYAKYGIEVRLVGGLSLSKFQHAFRRQFLARYFLPVLSYIRKDFNAKAA-DIIISLYRLYPENPPDRKLLKERALKEAMHELGHVFGLEHCPNPKCVMHFSNSIIDTDIKS.......... 168
5 -6.700[R] COG2823 Predicted periplasmic or secreted lipoprotein  ali follow..  12  47.....DGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVDGANEVYNEIRQGQPIGLGEASNDTWITTK-VRSQLLTSDLVKSSNVKVTTENGEVFLMGLVTEREAKAAADIASRVSGVKRV........... 183
6 -6.590[R] COG1451 Predicted metal-dependent hydrolase  ali follow..  11  111..................................................................................AEIRVATVFRNAPEP---------LRMIVVHELAHLKEKEHNKAPQYHQLEFDTRLWLTQLS.......... 173
7 -6.520[S] COG3091 Uncharacterized protein conserved in bacteria  ali follow..  13  19...............................................RHYLQLANQHLGTAYPEPKVNY------HQRGTNAGSAYLQSFEIRLNPVLLLENKQPFIDEVVPHELAHLLVYRQFGRVAPHGKE---RWMMEQVLKVPA...... 111
8 -6.510[S] COG3228 Uncharacterized protein conserved in bacteria  ali follow..  13  38IPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPARIVQSGQSWQQGPIVLNWLDIQDSFDASGFN-------LIIHEVAHKLGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDP 222
9 -6.310[C] KOG4631 NADH:ubiquinone oxidoreductase, NDUFB3/B12 subunit  ali follow..  20  1......................................................................................................................MGGGHHEPRDFPQLAQHEKR-LAQIGLKDPWIRNY. 46
10 -6.170[R] COG1078 HD superfamily phosphohydrolases  ali follow..  17  24..........................................LIDGEPLIQRLRY----KQLGFVYLVYPTATHTRFDHS-LGVMHIATLLGQRIMQLLGEVDEELLRHLRAAALLHDIGFSHSFEI........................... 107
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.