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Query: [P] COG0475 Kef-type K+ transport systems, membrane components, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNDHILINVIILLGTAVFIVAILKRFRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGELGVVFLLFAIGLELSFERLKAMRRYVFGLGSLQVLTTAIVIAGAMVLIDGNSSAAIITGGGLALSSTALVMQVIDENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLASNNKASLAVALGIAFLKAVTALLTIFIVGRVLLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGLSLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTLSIALICIKTLIITAFCILFGFNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADILLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIELGARLast
1 -105.000[P] COG0475 Kef-type K+ transport systems, membrane components  ali  100  1MNDHILINVIILLGTAVFIVAILKRFRLSPVLGYLIAGAAIGDHGLKIVTYDQTKLLGELGVVFLLFAIGLELSFERLKAMRRYVFGLGSLQVLTTAIVIAGAMVLIDGNSSAAIITGGGLALSSTALVMQVIDENRSQSTQIGRISLAILLLQDLAVVPLLVIVPLLASNNKASLAVALGIAFLKAVTALLTIFIVGRVLLRPVFSFISSESNNTSELPISMTLLIVLSAAWATETFGLSLALGAFVAGVLVAETEFRLQAEESIYPFKSLFLGLFFMTVGMNIDALEMYEKISHILTLSIALICIKTLIITAFCILFGFNKGVAFYSGLLLSQGGEFGFILFSLGKDSGVLEESTADILLLVVTFTMALTPLLAALGKKIAEKVDKGLGKTPTQMIELGAR 403
2 -96.900[P] COG4651 Kef-type K+ transport system, predicted NAD-binding component  ali follow..  27  4.ATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAGPFTPGFVDTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLLGMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLVMVLTLVLLPAVAGMMEQGLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMAR--SAATGSRELFTLSVLALALGIAFGVELFDVSFALGAFFAGMVLNESELSHRAAHDTLPLRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTALTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKY..................... 390
3 -44.800[P] KOG3826 Na+/H+ antiporter  ali follow..  17  66...RSIFVIFILLVAGIFAAKISKALRLPPLFGCLALGIIIKNITVFDQPPFVETMIRKVALVMIIVRWGLATDIHFLYENALMPVTIGLVTAIGEIIAVTIASFILNISFVMSIFCALILVTVSPAVTVPAMINFKESLKRIPENILAICCVDNLFCVILFMVLSSIIFTDAPI-ATTILLNAGSIVFGCIGGIVLGWILWRFPRS--DAPHTQFARITLLGTICIAVVIGTYLIKYSCSGFLAALITSAMSAKEKLECVESTYKYIWDSFALPLLFICLGMKFDCSTLTWEIVFLCIAVIAILLVRTILVMLVTLSSHINFKEQIVVALSLLPRATFQADLAPTLLLMATPFPDILKAAILSVLITAPIFDILLNL......................... 461
4 -40.200[P] KOG1650 Predicted K+/H+-antiporter  ali follow..  16  53....MLLQMSVIIITSRLLYRLLKPLKQGMISAQVLAGIILGPSLFGQSGKITLQTLSNLGFFIHLFLLGLRIDASIIRKAGSKAILIGTASYALPFSLGNLTVLFLKNTYNLPSTVISLNAMTSFPVTTTVLAELNILNSDLGRLATNCSIVCEAFSWIVALVFRMFLRDGTLASV----WSFVWVTALILVIFFVCRPAIIWLTERRSISIDKAGEIPFFPIIMVLLTISLTSEVLGVHAAFGAFWLGVSLPDGPLGTGLTTKLEMFTSLMLPCFISISGLQTNFFIIESHVKIIEAVILITYGCKFLGTAAASAYCNIQIGDAFSLALLMCCQGVIEIYTCVMWKDEKVLNTECFNLLIITLLLVTGISRFLVVC......................... 443
5 -24.800[P] KOG4505 Na+/H+ antiporter  ali follow..  14  11PHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYVAKLFVPTSTEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALRLSFLESLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLACNDGMAIPFLYLAIYLIIEKPARHAGVCIIILYECTFGCVLGAIIG-VIARKMIKFSERRGLMDRESFLVFYFVLALFCGGIGTIIGVDDLLVSFCAGAAFSWDSWKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMSVWRLVVLAICILIARRIPAVLLFKSFIINWREALFAG--FGPIGVGALYTCLVARAE-YCIQVMWPVVCFLVLSSIIV................................ 426
6 -21.300[P] COG3263 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain  ali follow..  15  1......................................MLAGVDGVGGIPFDNAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAALFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKG-LNERVGSTLEIESGSNDPMAVFLTITLIAMIQHHESNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIAL----PAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLL----RGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLL............................ 336
7 -19.000[P] COG0025 NhaP-type Na+/H+ and K+/H+ antiporters  ali follow..  16  2...EIFFTILILILVVSLSGVVTRMLQVPLPLMQIVCGALLAWPNFGLHVNFDPELFLVLFIPPLLFADGWKTPTREFIHHGREILGLALALVLVTIVGIGYLIYWMGIPLVAAFALAAVLSPTDAVALSGIVGKGR-IPKSIMGVLEGEALMNDASGLVALKFAIAVAMGTMIFTVSGATLEFLKVAIGGLLAGVAITWLYSKSLRIMSRWSGDDPATQIVLLLLLPFASYLVAEHLGVSGILAAVAAGMTISQSGIIRNAPLAMR-LEFVFNGMVFILLGLQLPTIQTWNLFADVAIIYGALLLLRFGWLWSMKKISKRFSDYTTRELWVASFAGVRGAITLAGVLSIYQLVFIATGVILLSVIIGVIALPPLLR.......................... 421
8 -14.700[P] KOG1965 Sodium/hydrogen exchanger protein  ali follow..  14  29........FVALLCACIVLGHLLEETRMNESITALIIGSCTG-IVILLISGGKSSRILVFSIYLLIFNAGFQVKKKQFFRNFMTIMLFGAIGTLISFVIISFGAKHLDLTIADYLAIGAIFSATDSVCTLQVLNQDE--TPLLYSLVFGEGVVNDATSVVLFNAIQRFDLTNINSAIALEFAGNFFYLFILSTALGVAAGLLSAFVIKKLYIGRHSTDREVALMMLLAYLSYMLAELFHLSSILTVFFCGIVMSTDKSKVTTKHTFAAMSFLAEIFIFLYVGMDALDIEKWDSIGVSSILLGLILLGRAAFVFPLSFLSNLTKSSPDEKIDLKKQVGAVSMALANQFTTSGHTKVLGNAIMITSTITVVLFSTVV............................ 433
9 -14.000[P] KOG1966 Sodium/hydrogen exchanger protein  ali follow..  14  25........ITTWLLVASLAKILFNLMKLPDSSLLIIVGLGLG-YFLNQTTLSGVHLDSHAFFLYLLFDAGYFMPNRALFKNFDSVLVFSVLGTLWNTFAIGGSLLIMPFTTFEILVFSALISAVDPVAVIAIFEEIH-VNEFLFINVFGEALFNDGVTVVLYQMFKSFALIGSENLSPWDYATGGLSFFVVALGGAAIGIIFAIATSLATKYTQGIKILAPVFIFLLPYMAYLTAEMVSLSSIIAIAVCGMLMKQGNITEAATNSVKYFTKMLATVIFMFLGLSTLTSEHHVDFIFIGATLVFCLIYRAIGIIVQCFILNKFRAKKFEVVDQFILSGAIAYGLVVSIPASIQAKPMFITTTICVIYFTVFLQGITIR.......................... 420
10 -11.700[R] COG3180 Putative ammonia monooxygenase  ali follow..  15  23.....VWQWCLLALLSAVFAGVLEMIGIPALMGPMIAGALVGMNGGTIRLPRQLFFCVQLAM-----MIAASMSPDLLVTFSGLFLAIILSVIGVSTLCGWTITRMGILPGTTAIWGSSAGAASTMLLMADAY----------GADARLVAFMQYLRVVFVASTATIVSHLWVSGVEAE-----------------------------ATHWFAPIAGLPFFMTLAVGIASGILGKILRVPAGLVPFAIGSALNITGTLT-------ELPQWLLALSFAMLGWNIGLGFARRALMPTIVSIVVLISFSGLLALLLIKVAGIDPLTAY---LATSPGGLDSIAVIAASSNVDLPFVMALQTA---LLIITLIGPALARF......................... 357
11 -9.680[S] COG2855 Predicted membrane protein  ali follow..  10  15...HFIPGLALSAVITGVALWGVAGAGFSALTLAILLGMVLGNTIYPHIWKSAKQYLLRLGIILY----GFRLTFSQIADVGISGIIIDVLTLSSTFLLACFLGKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEASKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPE---TFGIYIGSTVHEVAQVVAAGHAISPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEFAILFIVVAIFNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLIVGGGAINYVI.................................................................................... 344
12 -9.250[S] COG5505 Predicted integral membrane protein  ali follow..  11  14........WGFIAVWAAVSIGLEQRFKVSGAIIALAGAMVFTNVGVLPVESPVYDTVWSYVVPLAIPLLLFQINVRQIFKESRRLFLISSVGTVLGSILAFFLLKQHIGGMISASYIGGGVNFAAMAAKFET-----------GEYVSATVVADNFMMALLFFILISIPAESYWKRKDISLKDIAFNAGAAFALVAVSMKVSGYFKSIFSHPLLTGTLGDQYLVLTSLTVLIIFLFPRFFERLNGSQELGT--------------------FLIYLFFVVIGIPADLRLIVTNAPLILLFVFIIAISNLAVSLAAGKLFRVRLEEILLAVNATVGGPTTAAAMAIAKGWRELVAPIMLVGTLGYLIGNYV................................. 384
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Dunbrack RL Jr, Dunker K, Godzik A. Protein structure prediction in biology and medicine. Pac Symp Biocomput. 2000;(12):93-4.