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Query: [J] COG0532 Translation initiation factor 2 (IF-2; GTPase), from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDKKRINQIAKETGLTNAELVSAAQTLGFEVKSHSSSVTAEQAEKIIQSAKTGTDQTAKVAEKPVKKSQPKAAESAKKNKEDHPRTFAGKAVVEDPAILARIKAKEEAEKAAKVEVASTEHPVVTEKPKASEPVKKAEPKVEAKSEPKVEKVETKDNTATSKAEVKPENVADKKEPVVTEEKKKSLTQKPRIQIKVIKRAEDIKKEQAAARPEKKKFDKNRNDRNNRSDNRRPNQNGNGQGGNHYDKNRSSGQGQNQGQKRDKFASSGSAPATDSFTPATSGKTSRRDRDRKKSDNNRDNTKDGNRKGGPLRVNDNRNQVRNARNSNWNQKGGRGRYQNNQSSSVPATQRKFHELPESLEYEVGMNVQDIAKSIKREPAEIIKKLFMMGTMVNQNQSLDEDTIELILMDYGVTPVKKVEEDKSDIERLFVEDGYLKEENMVERPAVVTIMGHVDHGKTTLLDRFRESRVTEGEAGGITQHIGAYQIKANGKKITFLDTPGHEAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPQRVTQELTEHGVFPVAWDPENGSEFVEISAKFNQNLDELLDTVLLVAEVQELKADPTVRAIGTVVEARLDQGKGAIATLLVQQGTLHVQDPIVVGNTYGRVRTMTNDLGRRIKEAGPSTPIELTGLSDVPQAGDHFAVFEDEKAARAAGEERAKRAQLIKRQNTRRVNLDNLFDTLKEGQTKSVNIIIKADVQGSAEALAASLQKIEVEGVKVDIVHSAVGAISESDISLAAASNAIIIGFNVRPTGLAREQAAQEEVDIRLHSIIYKVIEEVETAMRGMLDPEFKEEIIGEAIVRETFNVSKVGTIAGFMVIRGKVARDASVRVIREGVVIHDGAIASLKHFKDDVKEVGNAQEGGLMVEDFNDVEIDDTFEVYKMVEIERKLast
1 -161.000[J] COG0532 Translation initiation factor 2 (IF-2; GTPase)  ali  100  1MSDKKRINQIAKETGLTNAELVSAAQTLGFEVKSHSSSVTAEQAEKIIQSAKTGTDQTAKVAEKPVKKSQPKAAESAKKNKEDHPRTFAGKAVVEDPAILARIKAKEEAEKAAKVEVASTEHPVVTEKPKASEPVKKAEPKVEAKSEPKVEKVETKDNTATSKAEVKPENVADKKEPVVTEEKKKSLTQKPRIQIKVIKRAEDIKKEQAAARPEKKKFDKNRNDRNNRSDNRRPNQNGNGQGGNHYDKNRSSGQGQNQGQKRDKFASSGSAPATDSFTPATSGKTSRRDRDRKKSDNNRDNTKDGNRKGGPLRVNDNRNQVRNARNSNWNQKGGRGRYQNNQSSSVPATQRKFHELPESLEYEVGMNVQDIAKSIKREPAEIIKKLFMMGTMVNQNQSLDEDTIELILMDYGVTPVKKVEEDKSDIERLFVEDGYLKEENMVERPAVVTIMGHVDHGKTTLLDRFRESRVTEGEAGGITQHIGAYQIKANGKKITFLDTPGHEAFTSMRARGASVTDITILVVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPQRVTQELTEHGVFPVAWDPENGSEFVEISAKFNQNLDELLDTVLLVAEVQELKADPTVRAIGTVVEARLDQGKGAIATLLVQQGTLHVQDPIVVGNTYGRVRTMTNDLGRRIKEAGPSTPIELTGLSDVPQAGDHFAVFEDEKAARAAGEERAKRAQLIKRQNTRRVNLDNLFDTLKEGQTKSVNIIIKADVQGSAEALAASLQKIEVEGVKVDIVHSAVGAISESDISLAAASNAIIIGFNVRPTGLAREQAAQEEVDIRLHSIIYKVIEEVETAMRGMLDPEFKEEIIGEAIVRETFNVSKVGTIAGFMVIRGKVARDASVRVIREGVVIHDGAIASLKHFKDDVKEVGNAQEGGLMVEDFNDVEIDDTFEVYKMVEIERK 944
2 -124.000[J] KOG1145 Mitochondrial translation initiation factor 2 (IF-2; GTPase)  ali follow..  32  2..............................................................................................................................................................................................................................................................................NQKLLKLENLLRFHTIYRQLHSLCQRRALRQWRHGFSSAYPVWTAQLCAWPWPTDVLNGAALSQYRLLVTKKEEGPWKSQLSSTKSKKVVEVWIGMTIEELARAMEKNTDYVYEALLNTDISLEADSHLDEVWIKEVITKAGMKLKWSKLKQDKVRKKDAVRRPQADPALLTPRSPVVTIMGHVDHGKTTLLDKFRKTQVAAVETGGITQHIGAFLVSLSGEKITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMKQTVESIQHAKDAQVPIILAVNKCDKAEADPEKVKKELLAYDVVCEDYGG--DVQAVPVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTDKGRGLVTTAIIQRGTLRKGSVLVAGKCWAKVRLMFDENGKTIDEAYPSMPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQEKGQEDLKIQIPLKPKEKRERDSNVLSVIIKGDVDGSVEAILNIIDTYASHECELELVHFGVGDISANDVNLAETFDGVIYGFNVNAGNVIQQSAAKKGVKIKLHKIIYRLVEDLQEELSSRLPCAVEEHPVGEASILATFSVTKKVPVAGCRVQKGQLEKQKKFKLTRNGHVIWKGSLTSLKHHKDDISIVKTGMDCGLSLDEDNEFQVGDRIVCYEEKQIQAK 720
3 -26.200[E] COG4917 Ethanolamine utilization protein  ali follow..  21  4...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IAFVGSVGAGKTTLFNALQGNYTLARK----TQAVEFNDK-------GDIDTPGHPRWYHALITTLQDVDMLIYVHGANDP--ESRLPAGLLDIGVSKRQIAVISKTDMPDADVAATRKLLLETGF---------EEPMFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHS.................................................................................................................................................................................................................................................................................................................................... 158
4 -22.500[J] KOG0462 Elongation factor-type GTP-binding protein  ali follow..  19  45...............................................................................................................................................................................................................................................................................................................................................................................................................................................................FGIVAHVDHGKSTLADRLLEMCGAVPPGQGITVKAQTAALRHRGYLLNLIDTPGHVDFSAEVSRSLAVCDGILLLVAANQGVQAQTIANFWLAFEKNIQIIPVINKIDLPGADIKSVETQLKNL--------EFNPEECLHISAKSGLNVDKVLEAII--DRVPAPTAIIDAPFRSMIFDSYFDHFRGAIAHIMVKEGSVKKGDKIQVGYLVCNMRTVNEAVGETLFAEEIKGVKPTVYAGLFPVETSDYESLKQERLCLNDPSVTVIPDSSKALGLGGVLHMEVFGARLSQEYDASVSVEYRAKIKDNETIRKKRYDGMEEIRILDPS-ESDVDSFLEPMVKVRMIVPNEMMGTVNGLCSECRGERGEITWRLPLAEVAVDFFERLKKLTSGSFDYEPDGWQDTRLVKLTILINSKEVSEFSQIIPAAMARDRAKILVQRLKREIFEVTIKACIGSSTKAQIVIQPMKRDFSQLLKGNFGGGGMERLNKKLSHQKK 621
5 -22.200[M] COG0481 Membrane GTPase LepA  ali follow..  19  7...............................................................................................................................................................................................................................................................................................................................................................................................................................................................FSIIAHIDHGKSTLSDRIQTCGGLSDREMGITIKAQSVTLNYKAKDLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMNLEVVPILNKIDLPAADPERVAEEIEDI--------GIDAMEAVRCSAKTGVGIEDVLEEIV--HKIPAPEGDPNAPLQALIIDSWFDNYLGVVSLVRIKNGTLRKGDKIKV-YNVDRLGIFTPKQVDTTILNCGEVGWVVCAIKDILGAGDTLTSHNNPASSVLPGFKKVKPQVYAGLFPISSDDYEAFRDALGKLSLNDASLFYEPENSTAMEIIQERLERTTAPTVVYEVEKTDLGNVITL-LTYEIPMGEVVLDFFDRLKSTSRQAADMVRVDIMINGERVDALALIVHKDNAPYRGRELVEKMRELIPRQQFDIAIQAAIGNHIIARSTVRKNVLAKCYGGDVSRKKKLLQKQKEGKKRMKSLGN-----VPQEAFLAILHVG............. 595
6 -21.700[J] COG3276 Selenocysteine-specific translation elongation factor  ali follow..  21  2..............................................................................................................................................................................................................................................................................................................................................................................................................................................................IIVTSGHVDHGKTALLKALTGTSLPEEKKRGMTIDLGYAYLPLENKVLGFIDVPGHEKFLSNMLAGLGGVHYAMLIVAADEGVAVQTKEHLAILRQLQFH-IVVITKADRTNSA-ESLIQTIKQDYSFLR------NANYFVTSAETGQGISELRHYLANLAE----LADTQKPFRYAIDRVFSVKGAGTVVTGTAFSGTVKVNDEILSTGQKIRIKAIAQNTSSEQGIAGQRLALNLNA-RTPMKRGDWLLQNEPLPPTDRISVQ-------------------LAEVPLNESQPVHIYH--ASRTTGKLTLLQGKNAAKNDRTLAEIILDSPLFLAFGDKLILRSGDTKTLIAGARVLEINSPKRHKRTEVRLNFLANL..................................................................................................................... 362
7 -21.200[T] COG1217 Predicted membrane GTPase involved in stress response  ali follow..  18  8...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IAIIAHVDHGKTTLVDKLKLSGTLDRKE-GITILAKNTAIKWNGYNINIVDTPGHADFGGEVERVMSMVDSVLLVVDAQDGPMPQTRFVTQKAFKAGLRPIVVVNKIDRPGARPDWVIDQIFDLFDNLGA-----TDEQLDFPIVYASALNGIAGLDHEKMHVPAPVVDTEGPFQMQISQLDYNSFLGVIGIGRITRGKVKSNTPVVAISDDGRILKIMGHHGLQRVEVAEAEAGDIVCVSGMEELSDTLCDPQNVEALPPLTVDQQVNDSPFAGREGKFVTSRNIKERLEKELLHNVALRVEPGDSPELSVLIETMRR-GRVRLEYTIPARGLIGFRNNFLTLTSGTGILFSHYGPIKAGEVSNRQNGVLVSMATGTALTYSLETLQSRGKLFLGP-----------GDEIYEGQLAGI-NDLVINPTKGKKLDNMRASGKDEVIALVPPIRFTLEQ-------------IADDELVEVTPKSILNENDRKRYERS 603
8 -18.800[J] KOG0460 Mitochondrial translation elongation factor Tu  ali follow..  18  55..............................................................................................................................................................................................................................................................................................................................................................................................................................................................NIGTIGHVDHGKTTLTAAITKCKAPEEKARGITISSAHVEYETANRHYAHVDCPGHADYIKNMITGAATMDGAIIVVSATDGQMPQTREHLLLARQVGVKIVVYINKVDMVEPD-MEMRELLSEYGFDGDN--------TPIVSGSALCALEGREPEIKLMEAVDSYITLPERKTDV-IEDVFSISGRGTVVTGRVERGTLKKGAEIEI-HLKTTVTGIMFKKQLDAAVAGDNCGLLLRSIKREQLKRGMIVAQPGTVAPHQKFKASFYILTKEEGGRRTGFV-DKYRPQLYSRTSDVTVELTHPDPNDSDKMVMPG------DNVEMICLIHPIVIEKGQRFTVREGGSTVGTA............................................................................................................................................... 432
9 -18.700[J] KOG0466 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  18  1......................................................................................................................................................................................................................................................................................................................................................................................................................MAGGEAGVTLGQPHLSRQDLTTLDVTKLTPLSHEVISRQATINIIGHVAHGKSTVVKAIRNITIKLGRPECYRSCGSSMPDEFPVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCQPQTSEHLAAIEIMKLKILILQNKIDLVKER-EQILAFVQGTVA---------GAPIIPISAQLKYNIEVVCEYI---VKKIPVPPRDFTSEPRLIVICEVDDLKGGVAGGSILKGVLKVGQETEV-SIFSKIVSL-FAEHNDLQYAAPGGLIGV-GTKIDPMVGQILGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNI--SLSTGGRVSAVKADLGKIVLTN............................................................................................................................................................................. 431
10 -18.100[J] COG0050 GTPases - translation elongation factors  ali follow..  20  14..............................................................................................................................................................................................................................................................................................................................................................................................................................................................NVGTIGHVDHGKTTLTAAITTVNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPIIVFMNKCDMVD-DEELLELVEMEVRELLSAYDFPGDDLPV-VRGSALKALEGEAEWEAKIIELAGYERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEI-TVKSTCTGVMFRKLLDEGRAGENVGVLLRGIK---ERGQEVYILSKDEGGRHFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNINMIVTLIHPI--AMDDGLRFAIREGGRTV-------GAGVVAK.............................................................................................................................................................. 391
11 -17.900[J] COG4108 Peptide chain release factor RF-3  ali follow..  18  18...............................................................................................................................................................................................................................................................................................................................................................................................................................................................FAIISHPDAGKTTITEKVLLFGRAIQVAGGISVTTSVMQFPYGDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEDRTRKLMEVTRLRDTPIVTFMNKLDREIRDPMELMDEVENE--CGKEFKGVYHIHRDETTALGNFGVDHMLDGLT-AERVVEASEEKFTGFVFKIQANMDPKHRDRIAFVRIVSGTYKQGMKMN--VNISDAVTFMAGDRARAEEAFAGDIIGLHNHGTI-QIGDTF-------------------------TQGETLKFTGI--------APELFRRIRLRDPLKQKQLLKGLVQLSEEGA--DLIVGAVG-----VLQFDVVVSRLKSEYNVEAIYEGVNVATARWVE............................................................................................................................ 477
12 -17.900[J] COG5257 Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase)  ali follow..  20  8..............................................................................................................................................................................................................................................................................................................................................................................................................................................................NIGLVGHVDHGKTTLTKALSGVTHSEETKRGISIRLGYADITFRKRKVSFVDAPGHETLMATMLSGAALMDGAILVIAANEPCQPQTKEHLMALDVIGVKVIVVQNKIDIVSKE-REIKEFVKGTCA---------DAPIIPVSAQQGANIDILIETI---EERIKTPKRDVDKPARMYVAADPEHLAGGVIGGSLVQGRLRVGDEI---------------------EIRPGIQVKKDGKQTWMSLHSTITGLVAGGEEMEEV---------------------------GPGGLVGVGTLTKADSSGSVAGEPGTLPPVRHSTMETHLLERVVGTKEETKVEPIKTGEPLMINVGTTTTVGVVKSARADDADVVLKLPACAEEGQRIALSRRVGAR----RLIGYGIIK....................................................................................... 408
13 -17.800[P] COG2895 GTPases - Sulfate adenylate transferase subunit 1  ali follow..  16  30...............................................................................................................................................................................................................................................................................................................................................................................................................................................................FLTCGSVDDGKSTLIDQLSSLHNDSKRHGGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASLLEVL---ETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVSGVESNVARIVTF-DGDREEAFAGEAITLVLTDEI-SRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIK------------------GKKTRARVDGIRYQVDINNLTQREVENLPLN----GIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAA........................................................................................................... 444
14 -17.700[J] KOG0465 Mitochondrial elongation factor  ali follow..  17  73...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IGISAHIDSGKTTFTERVAIHEVRGRDN-GITIQSAAWDKEGKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDRQMRRYNVPRVTFINKMDRMGSDPFRAIEQLNSKDEMAEMFLEEKEPTTQQISALANTGIQPVLDAIV-NEAKVNLVPAVQQPFVGLAFKL-EEGKYGQLTYVRVYQGRLRKGNYITKKVKVARLVRMHSSEMEDVDEVGSGEICATFGIDYVPDAVVSLSITPNSKDASNFSKKFDPESKETIISGMGELHLEIYVERMRREVTGKPQVSYRESITIPADFVIGTLSPVDDITKGNIFETAIVGGRIPDKYLAAVCEKGPLIGHRV------------LDVKMLINDGAIHAVDSNELSFK-IMEPIMNSVTSPNEFQGNVIG-KLQAVIQDTENGHDEFTLKAEC------------ALSTMFGFATSLRASTQG-EFSLEFSHYAPTAPHVQKELISEFQKKQA 759
15 -17.600[J] KOG0458 Elongation factor 1 alpha  ali follow..  18  170...............................................................................................................................................................................................................................................................................................................................................................................................................................................................FVVLGHVDAGKSTLMSQLRKLQRESETMGGVTVSICTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFEQTKEHMLLASSLGIHLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFEDNINWVPISGFSGEGVPNLMSTL----ENAAFKISKENEGINKIIPSKKTSNDLALVSGKLESGSIQPGESLTISEQSCIVDKITNHEETDVAIKGDFVTLKLRKAYPEDIQNGDLAASVDYSSIHSAQCFVL------------ELTTFDMNRPLLPGTPFILFI--VKEQPARIKRLISFIDK-GNTASKKKIRHLGSKQRAFVEIELIEVKRWIPLLTAHENDRLGRVVLRKDGRTIAA-GKISEITQ................................................................................................................ 611
16 -17.500[R] COG5258 GTPase  ali follow..  19  21..............................................................................................................................................................................................................................................................................................................................................................................DVDRMAGQLKRRLAE--EAVYLIGVLPDEELVKALETLREMARRVGASLYILRVSEGIRGKVAEVLLRAVSREEPPPT--TVVALGNVDAGKSTLVGVLTTGRLDDGKG-GRTSAVSAEVYKRSDKLVLLVDVGGHERYLRTALRGSSQPDYVMLVVAANSGVQKMTKEHLGIAVAIGIPVFVVVTRIDITPSE-QKTVEEVVRI-LAAKAMPAGRVAPVFYVSSVTGHGLDLLLRFLSLLPRR---RWDYGGEFLMYISDIYLVKGVGVVIGGLVEKGILHVGDRVWLGPY--VVKSI-HFNRTPVESAKAGSFITV-ALDKVEKVEKGMVLSARPLKAVREVTADVLVLRHPTVIRAGFSGVFHYKAVRTGGYIKEID-ELMVGDSGVVKIELSRPWHIDSGVFVFR---RILGRIIG.............................................................................................................................................................. 510
17 -16.800[J] COG0480 Translation elongation factors (GTPases)  ali follow..  20  13...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IGIAAHIDAGKTTTTERIKIGEVHEGTA-GITITAAAISTSWKDYQINIIDTPGHVDFTIEVERSMRVLDGVIAVFCSVGGVQPQSETVWRQADRYKVPRIAFINKMDRTGANFYRVHEQMRDRDDLMSKYFDGEPLTEEEISAFKNKGVQLMLDAVV-NGDAIERRADDNEPLAALAFKIMADP-YGRLTFVRVYSGVLKKGSYVLNATK-SRLVLMKADDRQDVEELRAGDLGAALGLKDT-LTGDTITDEGAPVILESLF------------------------------PEPVISVAVEPKTKNDMDKLSKALQSLSEEDPTFRVVIAGMG-----ELHLEILVDRMLREFKVEANVGAPQVAYRETIRKPVTNVEGKFIRQSGGKVVINLEPEFVSKIVGGVVPKEYIGPAEQGMKES--CESGIL---AGYPLIDVKATLVHGSYHDV-----DSSEMAFKIAGSMALKEAVLKASPVLLEPMMKVEV... 607
18 -16.800[J] KOG0459 Polypeptide release factor 3  ali follow..  19  104...............................................................................................................................................................................................................................................................................................................................................................................................................................................................VVFIGHVDAGKSTIGRQIQKYEKEAKDKSGKTVEVGRAHFETESTRFTILDAPGHKSYVPNMISGASQADIGVLVISARKGEFEQTREHVQLAKTLGVSLIVVVNKMDDPTVN-DEIEQKMVPF-LKASGYNTKKDVVFLPISGLMGKNMDQFFEVL----DSIEIPPRDPNGPFRMPII-DKFKDMGTVVMGKVESGSIREGDSLVVNKEQVKVVAICDEDKVKRAGPGENLRVRITGIEDE-LSGF-------------VLSSIVNPVPAVTEFVAQLQILELLDNAIFTAGYKAILHIHAVVEECEIIELKSQIDLKTRKPMKKKVLFVKNGAAVVCRIQV---TNSICIEKFSDFPQLGRFTLRTEGKTIAV-GKVTELLSSVSSA........................................................................................................... 532
19 -16.100[J] KOG0468 U5 snRNP-specific protein  ali follow..  15  134...............................................................................................................................................................................................................................................................................................................................................................................................................................................................VALVGHLHHGKTTFVDCLRYTDTLFTEQ-GCSIKATPVTLVLQDVKLNIFDTPGHVNFSDEATAAMRMSDGVVLFIDAAEGVMLNTERLLKHAVQERQAITVCINKIDRLILELKLPPQDAYFKDFAKRLWGDNIRPLLRLVCNRFMGDCSGFVDMCV-DIYRDMISCNQYGTLMVHSSKMPNDDCTFFQVLARIVSGTLHAGQEVVLGENYGRLWVFESRYKVELNRVPAGNWVLIEGIDQCIVKTSTIVDINVPEDLYIFRPLKFNTQ-KIAVEPVNPSELPKMLDGLRKVNKSYPLLSTRVEESGELDCVMHDLRKFGPDSTGPNILVDDTLPSEVDKNLLTAVKDSIVQGFQWGTREGPLCEEPIRNVKFKILDGVIQIIPTARRVAYSLMEPYLFVEVQAPADVSAVYTVRRRGHVTQDAPVSGSPIYTIKAFI----------PAIDSFGFETDLRTHTQG-FCLSVFHHWQIVPGDPLDKSIIIRPLEP. 926
20 -15.600[J] KOG0469 Elongation factor 2  ali follow..  18  22...............................................................................................................................................................................................................................................................................................................................................................................................................................................................MSVIAHVDHGKSTLTDSVSKAGIIAGSKACITIKSTAISLKYNGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIKPVLFMNKMDRALLELQLGAEELFQTKLMKNLWGLEGKPLMKVFMRKWLPAGDTMLQMIA-EAAVAIKTCDPNGPLMMYISKMVPSDKGRFYAFGRVFSGKVATGMKARI-KTIQRTILMMGRFIEPIEDIPSGNIAGLVGVDQYLVKGGTITTYKDAHNMRVMKFSVSPVVR-VAVEAKNPADLPKLVEGLKRLAKSDPMVQCIFEESG--EHIIAGAGELHLEICLKDLLKKSDPVVSYRETVQSESNDSVVAGFQWATREGVLSDENMRGVRFNVHDVTLHFYASVLTAEPRLLEPVYLVEIQCPEAVGGIYGVRRRGHVFEESQVTGTPMFVVKAYL----------PVNESFGFTADLRSNTGG-FPQCVFDHWQVLPGDAGTKPNQIVLDTRK 834
21 -15.100[J] COG5256 Translation elongation factor EF-1alpha (GTPase)  ali follow..  20  13...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LITIGHVDHGKSTLVHIIEEYRKEAEQKGGVTIDLAHRKFETDKYYFTLIDAPGHRDFVKNMITGTSQADAAILVISAREGVMEQTREHAFLARTLGVPMVVAINKMDATSPP-NEVKADAEKL--------GFKDISFVPISGYKGDNVTKLLQAL---DAFKVPEKPINKPLRIPVEDVYSITGIGTVPVGRVETGVLKPGDKVIFADKQGDVKSIMHHEPLQQAEPGDNIGFNVRGIAKN-KRGDVCGHLDTPPTVVKAFTAQIIVLNHPSVIAPGYKPVFHVHTAQVACRIDEIVKTLNPKDGTTLKEKPDFIKNGDVAIVKVIP-IPQLGRFAVRDMGQTVAAGQCI................................................................................................................................................. 422
22 -14.200[J] KOG0052 Translation elongation factor EF-1 alpha/Tu  ali follow..  17  10...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IVVIGHVDSGKSTTTRTIEKFEKEAQEMGGITIDIALWKFETAKYYITIIDAPGHRDFIKNMITGTSQADCAVLVVACGTGEFEQTREHALLAQTLGVKLIVACNKMDSTEPP-TEITNEVSGF---IKKIGNPKAVPFVPISGFNGDNMLELLEAL---DSIIPPQRPTDRPLRLPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFQNVTTEVKSVMHHESLPEAVPGDNVGFNVKNVSVKDIRRGSVCSDSKQDPAKEARTFHAQ--------------------------------VIIMNHPGQISNGYTPVLDCHTAHIACKFVDRRTGKKVEDFPKFLKSGDAGIVELIPTKPLCVESFTDYAPL--------FAVRDMRQTVAVGVIKSVEKSD............................................................................................... 445
23 -13.400[R] COG3596 Predicted GTPase  ali follow..  13  7.............................................................................................................................................................................................................................................................................................................................................................................................................................EVLQPLQNSLSGLPLWVSERILQQINQLTHYEPVIGIMGKTGAGKSSLCNALFAGEVSVSDVAACTRDPLRFRLQIGEHFMTIVDLPGDTEYAALYREQLPRLDLILWLIKADDRALATDEHFYRQGEAYRHKMLFVISQSDKAEPTSGGNILSTEQKQNISRK---QPVHPVCAVSVRLQWGLRVMAERMI................................................................................................................................................................................................................................................................................................................................................... 213
24 -13.200[R] KOG2486 Predicted GTPase  ali follow..  23  136.............................................................................................................................................................................................................................................................................................................................................................................................................................................................PEFALVGRSNVGKSSLLNSLRKRLALTSKKPGKTQCINHFRI---NDKWYLVDLPGYNKFTKDYFLNRSTLVSVFLLVDASIPVKPIDLEYASWLGQNQVPMTLIFTKCDKRKKKKNGGKKPEANIKEFQDQGFFETTPPWIMTSSVTNQGRDEILLHM.................................................................................................................................................................................................................................................................................................................................................... 308
25 -13.000[R] COG0218 Predicted GTPase  ali follow..  16  26.............................................................................................................................................................................................................................................................................................................................................................................................................................................................PEIALAGRSNVGKSSFINTMRKNLARTSGKPGKTQLLNFFNI---DDKMRFVDVPGYRVSKKEREKWGCMIE-VVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRG-----KWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAI.................................................................................................................................................................................................................................................................................................................................................... 191
26 -12.900[R] KOG0075 GTP-binding ADP-ribosylation factor-like protein  ali follow..  22  23...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LTLVGLQFSGKTTFVNVIASGQFAEDMI---TVGFNMRKITRGNVTIKVWDIGGQPRFRSMWERYCRGVNAIVYMVDAAD-SRNELHSLLDKPQLAGIPVLVLGNKRDLPGADETGLIERMNLSSIQDREI------CCYSISCKEKDNIDITLQWLI................................................................................................................................................................................................................................................................................................................................................... 178
27 -12.800[R] KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3  ali follow..  21  20...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILLLGLDNAGKTTLLKQLASEDISH------TQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWKNYFENTDILIYVIDSAD-TGQELAELLEEEKLSCVPVLIFANKQDLLTAPASEIAEGLNLHTIRDRVW------QIQSCSALTGEGVQDGMNWVC................................................................................................................................................................................................................................................................................................................................................... 174
28 -12.600[U] KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3)  ali follow..  20  24...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILMLGLDAAGKTTILYKLKLNQSVV------TVGFNVETVTYKNIKFNVWDVGGQDKIRPLWRHYFTGTKGLIFVVDSAD-ARQELHRIISDREMRDCLLLVLANKQDLPGASPAQITDVLQLDKLKDRLW------NVQPTCALTGDGLLEGLAWLS................................................................................................................................................................................................................................................................................................................................................... 178
29 -12.600[U] KOG0070 GTP-binding ADP-ribosylation factor Arf1  ali follow..  20  20...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILMVGLDAAGKTTILYKLKLGEIVT------TIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSND-ARDELHRMLNEDELRDAVLLVFANKQDLPNANAAEITDKLGLHSLRQRHW------YIQSTCATSGEGLYEGLDWLS................................................................................................................................................................................................................................................................................................................................................... 174
30 -12.500[U] KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1  ali follow..  22  20...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILILGLDGAGKTTILYRLQVGEVVT------TIGFNVEQVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAIIYVVDSAD-SKDELLYMLREEELAGAILVVLANKQDMDGCTVAEVHHALGLENLKNRTF------QIFKTSATKGEGLDQAMDWLS................................................................................................................................................................................................................................................................................................................................................... 174
31 -12.400[UZ] KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2  ali follow..  22  19...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LLMLGLDNAGKTTILKKFNGEDIDT------TLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSAD-CQRELQSLLVEERLAGATLLIFANKQDLPGASSNAIREALELDSIRSHHW------CIQGCSAVTGENLLPGIDWLL................................................................................................................................................................................................................................................................................................................................................... 173
32 -12.400[R] COG1100 GTPase SAR1 and related small G proteins  ali follow..  22  21...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILILGLDGAGKTTILYRLQIGEVVT------TIGFNVETLSYKNLKLNVWDLGGQTSIRPYWRCYYADTAAVIFVVDSTD-ASKELHLMLQEEELQDAALLVFANKQDQPGASASEVSKELNLVELKDRSW------SIVASSAIKGEGITEGLDWLIDVIKEEQL........................................................................................................................................................................................................................................................................................................................................... 183
33 -12.300[R] COG2229 Predicted GTPase  ali follow..  18  6...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IIFTGPVGVGKTTAIAAISDEALVQTDASAVAMDYGAISLD-EDTKVHLYGTPGQERFNFMWEILSQGSMGLVLLL---DNARTNPLKDLEFGLLEKAPVVVGITKMDIRSQGIDVYHKYLAKHNL---------NVPVFEIDARKEDDVKQLVSAMLFSID............................................................................................................................................................................................................................................................................................................................................... 173
34 -12.300[U] KOG0077 Vesicle coat complex COPII, GTPase subunit SAR1  ali follow..  20  23...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILFLGLDNAGKTTLLHMLKDERLVQHQP---TQHPTSEELSIGKIKFKAFDLGGHQIARRVWKDYYAKVDAVVYLVDAYD-SKRELDALLSDEALATVPFLILGNKIDIPYASEDELRYHLGLTNFTTGK--GVRPLEVFMCSIVRKMGYGEGFKWLS................................................................................................................................................................................................................................................................................................................................................... 189
35 -11.300[R] COG1160 Predicted GTPases  ali follow..  14  4.............................................................................................................................................................................................................................................................................................................................................................................................................................................................PVVALVGRPNVGKSTLFNRLRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGGEEKMAEQSLLAIDEADIVLFLVDARAGLTAADIGIANYLQRQNKITVVVANKTDGIDADSH------------CAEFYQLGLGEIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTS-ALDEELEEEQDKNIKIAIV--GRPNVGKSTLTNRILGEDRVVVFDMPGTTRDS-----------IPMERDGQQYTLIDTAGVRK------------------------------------------RGKVHLAVESVIKTLQAIQDANVVLLTIDAREN-ISDQDLSLLNAGRSLVIVVN-DVKDRVKSELDRRLDFIDFARVHF--VGNLFDSIKEAYACATQKMTTSLLTLQMATDEHQPPMIGGRRI---KLKYAHPGGYNPPIIVVHGNQMDKLKRYLSNYYRKSLKII-GSPIR...................... 467
36 -10.800[U] KOG0076 GTP-binding ADP-ribosylation factor-like protein yARL3  ali follow..  19  20...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILILGLDNAGKTTFLETLKKEYSLAKALEKIQPTVG-QNVATSKQILKFWDVGGQESLRSMWSEYYSLCHGIIFIVDSSD-CSTTLQSVVMDEEIEGVPILMLANKQDRQDREVQDIKEVFNKIAEHISA-----DSRVLPISALTGEGVKDAIEWMIVRLERNKKSRPPIYK.................................................................................................................................................................................................................................................................................................................................... 198
37 -10.800[R] KOG0394 Ras-related GTPase  ali follow..  20  11...............................................................................................................................................................................................................................................................................................................................................................................................................................................................VIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVQFEDRLFTL-DTAGQERFQSLGVRGADCCVLVYDVNSMKENLNNWREEFLIQASPSNFPFVLIGNKVDVDDGNSRVVSEKKAKA--------SKGNIPYFETSAKVGTNVEEAFQCIA................................................................................................................................................................................................................................................................................................................................................... 173
38 -10.800[R] COG1084 Predicted GTPase  ali follow..  16  163.............................................................................................................................................................................................................................................................................................................................................................................................................................................................FTVVIAGFPNVGKSTLLRTLTGAEPEVADYPFTTKGIQIGHLERKWKRIQVIDTPGNNIELQAMVALENIADVIMFIFDASETCGYTLESQYS-RSVFDIPVVTVFNKMDL--AENVKYLEEYINM------------EDPLKVSAFEGRGVSKIIKKLLYEKETREAHDN........................................................................................................................................................................................................................................................................................................................................ 335
39 -10.700[R] KOG0393 Ras-related small GTPase, Rho type  ali follow..  14  6...............................................................................................................................................................................................................................................................................................................................................................................................................................................................CVVVGDGAVGKTCLLLSYTTNAFPGEYILTVFDTYSTVMVDGRPINLSLWDTAGQDDYDQFRHLSFPQTDVFLVCFALNENVRAKWYPEVSH--CPNTPIILVGTKADLREDRDTIERLRESRLQPVSHTQGYVKAVKYLECSALTQIGLKQVFDEAIRTGLTPPQTPQTRAKKSNCTV.............................................................................................................................................................................................................................................................................................................................. 194
40 -10.400[R] COG1159 GTPase  ali follow..  18  7...........................................................................................................................................................................................................................................................................................................................................................................................................................................................YCGFIAIVGRPNVGKSTLLNKLLGQKISTSRKAQTTRHRIVGIHTEGPYQAIYVDTPGNRLMNKAASSSIGDVELVIFVVEGTRWT-PDDEMVLNKLRDGKAPVILAVNKVDN-------VQEKVDLLPHLQFLASQMNFLDIVPISAETGMNVDTIAGIVIIREKLMRFLGAELPYSVTVEIERFVTNERGGYGLILVEREGQK----MVIGNKGAKIKTIGIEARKDMQE............................................................................................................................................................................................................................................................................. 267
41 -10.300[R] KOG0395 Ras-related GTPase  ali follow..  23  22...............................................................................................................................................................................................................................................................................................................................................................................................................................................................MVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDN--VKRLQKQILEVKSCELPMVICGNKNDHGEL--CRQVPTTEAELLVSGDEN----CAYFEVSAKKNTNVDEMFYVLFSMAK............................................................................................................................................................................................................................................................................................................................................... 191
42 -10.300[U] KOG0090 Signal recognition particle receptor, beta subunit (small G protein superfamily)  ali follow..  17  53..........................................................................................................................................................................................................................................................................................................................................................................................................................................................TKSNTVLLSGLSGSGKTVLFYQLRDGSSHQGAVTSMEPNEGTFVLKGKVKPVHLIDVPGHSRLISKLEEYLPRAAAVVFVVDALE--IRAASEYLASVIKNKTPVLLCCNKTDKVTAHTKEFIRKQMEKEIDKLR-----VSRSAISTADIANDFTLGIEGEVFSFSHCHNKVT----AEASGLTGETDQVQEFIREHV............................................................................................................................................................................................................................................................................................................... 258
43 -10.200[R] KOG0080 GTPase Rab18, small G protein superfamily  ali follow..  20  11...............................................................................................................................................................................................................................................................................................................................................................................................................................................................ILIIGESGVGKSSLLLRFTDDTFDPELAATIGVDFKVKTISVDGNKAKL-DTAGQERFRTLTPRGAQGVILVYDVTRRDVKLDNWLNELETYCTRNDIVNMLVGNKIDKENREVDRNEG---------LKFARKHSMLFIEASAKTCDGVQCAFEELVEKIIQTPGLWESENQNKGVKLSHREEGQGG..................................................................................................................................................................................................................................................................................................................... 196
44 -10.100[P] COG0370 Fe2+ transport system protein B  ali follow..  14  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................SQNTYCILGNPNTGKTSLFNALTGSYEYVGNWSGVT--VEKKVGTLRSKTGKLIDLPGIYDLNPISRDETVVTRFLCMLNIVDSSQIERNLNLTVQLLEYGAPVVMGLNMIDVAAGRGIHLNIQNLAKKL---------RIPILPVVARSGKGTEDILSTL---SEKHVAPAIPLVLQYGEPAEKAIKEIQALTKELIPAKQSRWLAIQFLSKNEVTEAFLTSNSAFEQLQQIRAELESEL--------NGKLENHFHQVRASYIHDICLTSVEYTRNSDIPLSDKLDKIFTHKLLGIPIFLGIMW---GGSLTDWVTSFLTTIGASGFIIDLVADGIIAGVGGVLVFVPQILVIFFGYMARIAVVMDRVMEIFGLNGKAFPMIIGFGCNVPGIMAARSIEESKERTLTILVSPFM-RLPVYALFVGVFFEKHQALVVLSLYVIGILMALIVTKILSKTILKKDVVEL................................. 488
45 -9.950[U] COG3210 Large exoproteins involved in heme utilization or adhesion  ali follow..  16  4..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TMNKNLYRI----------------IFN--KVRGM----IVVADIAASGRASSSPSSGLGHTSTLSFSLLLALG-ADASAPGNQQ---------TIINSANG---TPQVNIQAPSSGGVSR------------NVYSQFDVDGRGVI----LNNGHGVNQTEL--GGFID-GNPWLAR---GEASIILNE----VNSRDPS---KLNGYIEV--AGRKAQVV--------IANSAGITCEGCGFINANRVTLTTGQAQLNNGQLTGYDV--RGDIVTGMDSSRQDHTDLIARSVKVN------AGIWANELSVTTGRNQV-VAVDVAHAGKIRLIGTESGVGVHNAGEIGASAGDITITADGMLMNS------GQINSSQQLVVNTAADIE----NTGVLYAQGNTQLTTAGTLSNSGTLAAGGDTSVRAAEVNS............................... 394
46 -9.890[U] KOG0094 GTPase Rab6/YPT6/Ryh1, small G protein superfamily  ali follow..  21  12...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LVFLGDQSVGKTSIITRFMYDKFDTTYQATIGIDFLSKTMYLEDRTVRL-DTAGQERFRSLIPRDSSVAVVVYDVANRLS--TSKWIEEVRNERAGDVIIVLVGNKTDLVEKRQVSIEE--------GDSKGREYGVMFIETSAKAGFNIKPLFRKIA................................................................................................................................................................................................................................................................................................................................................... 167
47 -9.830[U] KOG0092 GTPase Rab5/YPT51 and related small G protein superfamily GTPases  ali follow..  16  23...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKF-DTAGQERYHSLAPRGAQAAIVVYDITNEES--AKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQE--------AQSYADDNSLLFMETSAKTSMNVNEIFMAIALPKNEPQNPGANSARGRGVDLTEPTQPTRNQCCS................................................................................................................................................................................................................................................................................................................. 214
48 -9.820[Q] COG3321 Polyketide synthase modules and related proteins  ali follow..  13  5..........................................................................................................................................................................................................................................................................................................................................................................VTPIAVIGMGCRLGINSPDKLWESLLRGDNLVTEVPPDRDVAGFDAEFFGISEREATSIDPQQRLLLETSWEAIEQGGLDPSTAVFTGLTHEDYLVLTTAAG--SPYVVTGLNNSVASGRISHTLGLHGPAMT-FDTA-HLACRSLHDGESDLAGCAVLLLSSTGRCKSFAADADGFVRSEGCAMVL-LKRLPDALRDGNRIFAMILGTATNQD---GGTE-----LMMPSEDAQVAVYQAALAVATIGVVEAHGTGTPIGDPIEYRLARVYGAGTPCALGSAKSNMGHSTASAGTVGLIKAILSLRNGLVDRLSDDLTEIRVAVSSFGMSGTNVHVIVEEAPSEACAPDVPETSPGTGLSSTSIAALRETARQLATWVEEHQDSVVLSDLAYTLPELVEGLCEIADGDAGPVWVFSGQGSLLANEPVFAATITKLEPVIAAESSFSVTEAITAPE-TVTGIDKVQPSVFAVQVALATTMRP---GAVIGHS----------MGESAAAVVA-GALSLEDAARVIRSKLM--SGAMGSVELPAKQVNSLMARGIDDVVISVVASVIGGALIAQWEQRDVMAR 723
49 -9.790[R] KOG0088 GTPase Rab21, small G protein superfamily  ali follow..  16  15...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IVLLGEGCVGKSSLVLRFVENKFSCKHLSTIQASFQNKTVNVEDCQADL-DTAGQEKYHALGPRGSNGVLLVFDITDRKS--VKNWVLEIKTCLGNTAEILIVGNKIDLEEERQVTRQD--------AEAYAESEGALYMETSAQDNVGISDAFESLT................................................................................................................................................................................................................................................................................................................................................... 170
50 -9.780[NU] COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1  ali follow..  13  610..............................................................................................................................................................................................................................................................................................................................................................................DAEKMVASLKQAFSRIVAETKGAGTGLSSNSARLETGAVTYQAQFFSG---LIAYHVDKVTGALTPFWNANFPAWEQRV-ITFANGALASASAQQINYLRGDRSQEGNVPGKLRIMG----DIVNSQPLYVGAPAYAAFVAQQANRAP-----VVYVGANDGML--------HAFDANVPAMPKLLEY----TDQNYVHQYYVDGELTAAD-KSGWRSVLVGTLGRGGKGLFAL--------DV----TDPSNIRLLWDKTSAEIGGLGNT-----------LSKPMIVQTSDGTWSVLL---GNGPNSTADNAQLIVMNLLT----GHATQVVVSKASSNGLSG-----------------------LPWSSQSNGITDRVYAGDLLGTLWRF-----TFSDNAWKVAPLFTATYQGKAQPISATRSTGRMWIFFGT-------RVLSSHDMDNKEVQSWYGLIDQGTTIPTGLSQVQIVDEGVVNGYAVRTVSDPKNIGTDGWYMKQG--ERMIVSNMFRGAALIGTTRIPD------------NSDICKLSGSGF-NPFTGGRLG.......... 1144
51 -9.640[R] KOG0091 GTPase Rab39, small G protein superfamily  ali follow..  20  12...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LILIGDSTVGKSSLLKFFTDGKFAELSDPTVGVDFFARLIEMKDGKLQLWDTAGQERFRSITKRNSVGVLLVYDISNHAEHIPLWMMEAQRHIEPHRPVFALVGCKLDLINAGGHREVTT-------AQKFAKQHGLHFVETSARSGANVEEAFRMVT................................................................................................................................................................................................................................................................................................................................................... 172
52 -9.610[U] KOG0096 GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily  ali follow..  20  15...............................................................................................................................................................................................................................................................................................................................................................................................................................................................LVLVGDGGTGKTTFVKRHLTGEFEKKYIATIGVEVHPLSFYTNFGEIKF-DTAGQEKFGGLRDGYYINAQCAIIMF---DVTSRITYKNVPNRVCENIPIVLCGNKVDVKERKVKAKTITFHR----------KKNLQYYDISAKSNYNFEKPFLWLA................................................................................................................................................................................................................................................................................................................................................... 167
53 -9.600[OK] COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase  ali follow..  18  1.........................................................................................................................................................................................................................................................................................................................................................................................................................................................MKRPLIIGVGGPVGAGKTMLIERLYSMAAITNDASMNFAAIEEMCDKHPDLQLLFLESGGDNLSATFSPDLVDFS-IYIIDVAQGEKIPRKGGQGMIKSD------LFIINKVDLAGANVEVMKADTLKSR---------GNKDFFVTNLKTDEGLKSVADWIEKRLQLALLE.......................................................................................................................................................................................................................................................................................................................................... 205
54 -9.470[T] KOG4252 GTP-binding protein  ali follow..  20  12...............................................................................................................................................................................................................................................................................................................................................................................................................................................................MVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRL-DTAGQEEFDAITKRGAQ----CVLVF---STTDRGSFEAVSSAEVGDIPTVLVQNKIDLLDDSCIKNEE--------AEALAKRLRLRFYRTSVKEDLNVNEVFKYLA................................................................................................................................................................................................................................................................................................................................................... 166
55 -9.440[O] KOG0734 AAA+-type ATPase containing the peptidase M41 domain  ali follow..  14  283.............................................................................................................................................................................................................................................................................................................................................................................................................................HVKGVEEAKQELQEVVEFLKNPQKFTILGGKLP-ILLVGPPGTGKTLL------ARAVAGEAD-----------------VPFYYASGSE-FDEM-------------------GVGASRIRNLFREAKANAPCVIFIDELDKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGA---TNFPEALDNALIRPGRFDMQVTPDVKGRTEILKWYLNK-DQSVDPEIIARGT--------VGFSGAELENLVNQAALKAAVDG-----EMVTMKELEFSKDKI-LMGPERRSVEIDNKNKTITAYHESGHAIIAYYTK-----DAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFG--TDHITTGAS-NATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQEIRILL-SYERAKHILKTHAHKNLAEALLTYETLDAKEIQIVLEG....................................................... 710
56 -9.400[U] KOG0095 GTPase Rab30, small G protein superfamily  ali follow..  21  12...............................................................................................................................................................................................................................................................................................................................................................................................................................................................IVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVGFMIKTVEINGEKVKL-DTAGQERFRSITQRSANALILTYDITCEES--LPEWLREIEQYASNKVITVLVGNKIDLAERREVSQQR--------AEEFSEAQDMYYLETSAKESDNVEKLFLDLA................................................................................................................................................................................................................................................................................................................................................... 167
57 -9.400[U] KOG0086 GTPase Rab4, small G protein superfamily  ali follow..  19  11...............................................................................................................................................................................................................................................................................................................................................................................................................................................................FLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKL-DTAGQERFRSVTRRGAAGALLVYDITSRET--LAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLE--------ASRFAQENELMFLETSALTGENVEEAFLKCAILNKIDSGELDPERMGSGI................................................................................................................................................................................................................................................................................................................................ 187
58 -9.340[U] KOG0098 GTPase Rab2, small G protein superfamily  ali follow..  24  9...............................................................................................................................................................................................................................................................................................................................................................................................................................................................YIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTIDGKQIKL-DTAGQESFRSITRRGAAGALLVYDITRRDT--LTSWLEDARQHSNSNMVIMLIGNKSDLEARREVKREE--------GEAFAREHGLVFMETSAKTAANVEEAFIDTAIYRKIQEGVFDINNEANGIKLGPQ........................................................................................................................................................................................................................................................................................................................... 190
59 -9.220[U] KOG0097 GTPase Rab14, small G protein superfamily  ali follow..  23  14...............................................................................................................................................................................................................................................................................................................................................................................................................................................................YIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKL-DTAGQERFRAVTRRGAAGALMVYDITRRST--LSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTYEE--------AKQFAEENGLLFLEASAKTGENVEDAFLEAA................................................................................................................................................................................................................................................................................................................................................... 169
60 -9.200[U] KOG0087 GTPase Rab11/YPT3, small G protein superfamily  ali follow..  23  13...............................................................................................................................................................................................................................................................................................................................................................................................................................................................TVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGVEFATRNIVLDNKKIKA-DTAGQERYRAITSRGAVGALIVYDITKQSS--VGRWLKELREHADSNIVIMLVGNKTDLLHLRAVSTEE--------AQAFAAENNLSFIETSAMDASNVEEAFQTVL................................................................................................................................................................................................................................................................................................................................................... 168
61 -9.150[O] KOG0736 Peroxisome assembly factor 2 containing the AAA+-type ATPase domain  ali follow..  12  390........................................................................................................................................................................................................................................................................................................................................................................ILASVLSPPLCPSALASKLR---VAVLLHGIPGCGKRTV----VKYVARRLGLHVVEFSCHSLLASSERKTSTALAQ-NMARRYSPTILLLRHFD-----VFKNLGSQDGSLGDRVGVSFEIASVIRELRGHQVLLIASLNDEQ-LVGQTSGFLPRDLQALVADAGANLYISQESETKKINSLSDDLHKLTAKEDFTKA--DRSKKRNASANVKWDDVGGLEDVK------------TSILDTVQLPLLHKDLFSSGLRKRSGVLLYGPPGTGKTLLAKAVATECSLNKGPELIIGESEKNVRDIF----EKARSARPC----VIFFDELPARGAS---VMDRVVSQMLAEIDGLSDSSQDLFIIGASNRPDLIDPLRPGRFKLLYVGVNADASYRERVLKALTRKFKSEDVSLYVAKKCPSTFTGADMY-ALCADAWFQAAKRKVSKSDSGDMPTEEDDPDSVVV---EYVDFIKAMDQLSPSLSITELKKYEMLRDQFQGRS................................................................................ 972

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Godzik A. Fold recognition methods. Methods Biochem Anal. 2003;44:525-46. Review.