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Query: [E] COG0549 Carbamate kinase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIVTHGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGINKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVVASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLAEMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAAASFARSRAGREALITVLSKAKEGIEGKTGTVICQLast
1 -103.000[E] COG0549 Carbamate kinase  ali  100  1MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIVTHGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGINKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVVASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLAEMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAAASFARSRAGREALITVLSKAKEGIEGKTGTVICQ 310
2 -55.300[E] COG0548 Acetylglutamate kinase  ali follow..  19  25.HKTIVVKYGGHAMGNA-----ELGRAFASDIALLKQSGVNPIVVHGGGPQIGAMLNRMGIESKFEGGLRVTDEKTVEIVEMVLAGSINKEIVALINQ---------TGEWAIGLCGKDGNMVFAEKAKKTIRDPDS-----------------------NIERVLDLGFVGDVVEVDRTLLDLLARSEMIPVIAPVAPGRDGHTYNINADTFAGAIAGALNATRLLFLTDVPGVL----NKKGELIKQLSVAEARALIADGTI-SGGMIPKVETCIEAIKAGVQGVVILNGKSVLLEIFTEHAGTLIV. 294
3 -38.700[R] COG1608 Predicted archaeal kinase  ali follow..  16  4STEPVILKLGGSAITDKGAEGVVKEAALLRIAREVSGFRGKMIIVHGAGSFGHTYAKKYGLDRNFDPE-----------------GSIVTHESVKKLASRVVEALNGFGVRAIAVHPMGCTVCRNGR--------------------------------------IESMYLESIKLMLEKGFVPVLHGDVVM-------DLELGTCILSGDQIVPYLAKELGITRLGLGSAEDGVLDMDGKPVPE-ITPENFEEFRQCIGGSG-VTGGMLGKVLELLELSKNSSITSYIFNAGDNIYRFLNGEIGTRISP 256
4 -35.800[E] KOG2436 Acetylglutamate kinase/acetylglutamate synthase  ali follow..  12  97.QQFAVIKVGGAIISDN-------LHELASCLAFLYHVGLYPIVLHGTGPQVNGRLEAQGIEPDYIDGIRITDEHTMAVVRKCFLE----------QNLKLVTALEQLGVRARPITSGV--------------------------------------FTADYLDKDKYKLVGNIKSVTKEPIEASIKAGALPILTSLAETASGQMLNVNADVAAGELARVFEPLKIVYLNEKGGIING--STGEKISMINLDEEYDDLMKQSWV-KYGTKLKIREIKELLDYLPRSSSVAIINDLQKELFTDSAGTMIRR 350
5 -28.800[E] KOG1154 Gamma-glutamyl kinase  ali follow..  15  79.AQRVVVKLGSAVITREDECGLARLASIVEQVSELQQSGRQMLIVSSGAVAFGRQKLRQEL----------------------VMSMSMRQTLRGPSGMTADKRACAASGMPGLMSLYEQLFQQ--------YGITVAQVLLTKPDIDDDQRRKNLQ--------------ATIESLLSLNIIPIVNANDAVAPDPKLNMHIS-----DNDSLAARLSAEIEAELLIILSNVNGVYTGPPEGSRLLYTYVPSENSGVT-ANSKFGTGGMESKVTACVNALNNGV-TTVITNGLDAITDAVAGKIGTMFC. 344
6 -25.900[F] COG0528 Uridylate kinase  ali follow..  15  8..KRVVLKLSGEALAGEKGFGINIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSD--------GMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRR-----------------------------------------------------AIRHLEKKRVVIFAAGIGNP----------------STDTTAALRAAEVEADVILMGKNVDGVYSADPKKDAVKYEHLTHIQM--------LQEGLQVMDSTASSFCMDNNI-PLTVFSIMENIKRAVMGEIGTLITK 240
7 -25.500[E] COG0263 Glutamate 5-kinase  ali follow..  15  30.PQTVVVKLGTSVLTGGTLADRAHMVELARQCAELKKQGHSVVIVTSGAIAAGREHLGYPALPNAISSKQ----------------------------------LLAAVGQSRLIQVWESLFAIYGIKIGQMLLTRADLDDRER-----------------------LNARDTINALVENGIVPVVNENDAVATNEIKVG--------DNDNLSALVGILCGADKLLLLTDQKGLFTADPRKDPNAQLIKEVTTIDDTLRKTTLGTGGMATKLQAADIARRAGI-EVIIAAGRNVIFDSLSDEQGTRFL. 282
8 -23.000[R] COG2054 Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases  ali follow..  10  1....MIVKIGGSVADR------------LEVVFEALENLQRVYAIPGGWIFADLVRKIDAEK-----RLSSSTSHWMAITAMSAYGFYMAETASRFGFKVIEPEDFNF--------------------------------------------------------------PDAKAVLLPYRLLRKYDE--------------PHSWEVTSDSIAVWIAAKAGFTEIVKVTAAGGVK----ELDGKIVEEVRASELKTDV-------------VDGYTPKLLVKYGINMFVCSPEELKNYILRGRGTLIV. 198
9 -13.300[E] COG5630 Acetylglutamate synthase  ali follow..  11  51..NHCLFFIRDLHKVAP-----AILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLH--------------------------------------------------------------------------------------LKEGLTKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCPHIDKFFILNNAGGIPSG--ERNDNAHVFINLSQELEHLSS-SLSHNISTLTKREPRSQNLLHRMEVYVKKD.................. 250
10 -13.000[E] KOG0456 Aspartate kinase  ali follow..  10  85.GITCVMKFGGSSVASA-----ERMKEVADLILTFPEESPVIVLSAMGK--TTNNLLLAGEKAVSCGVSNASEIEELSIIKELHIRTVKELNIDPSVILTYLEELEQLLKGIAMMKELTLRTRDYLVSFGECLSTR-AAYLNTIGVKARQYDAFEIGFITTDDFTNGDILEATYPAVAKRLYDDWMHDPAVPIVT--KGWKTGAVTTLGSDLTATTIGKALGLKEIQVWKDVDGVLTCDPTKRATPVPYLTFDEAAELAYFGALHPQSMRPAREGEIPVRVKNSYN--------------PKAPGTIITK 382
11 -12.800[E] COG0527 Aspartokinases  ali follow..  13  14..GWVVQKFGGTSVGKFP------IKIAVDVAKEYLSTKRVALVCSARSTDTKAEGTTTRLIRATEAALRPAVGSVHDLVRIIETDHAARDFIQDVGIQDELIDAFHADCVELVLSEVSPRTRDLVIGMGERLSCRFMAAVLKDQGIDSEFIDMSHIIDEQREWRNLDASFYAYLASQLASKVTAVGNKVPVVTGFFGMVPGGLLSQIGTDFCAALLAVGLNADELQIWKEVDGIFTADPRPTARLLPLITPEEAAELTYYGSIHPFTMSQVVHARIPIRIKNVGN--------------PRGKGTVIFP 318

FFAS is supported by the NIH grant R01-GM087218-01
1 4 3 0 4 3   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zhang Y, Stec B, Godzik A. Between order and disorder in protein structures: analysis of "dual personality" fragments in proteins. Structure. 2007 Sep;15(9):1141-7.