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Query: [H] COG0853 Aspartate 1-decarboxylase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFRTMLGGKIHRATVTEADLNYVGSITVDQDLLDAAGIYPNEKVAIVNNNNGERFETYTIAGKRGSGVICLNGAAARLVQKSDIVIIMSYVQLSEPEIAAHEPKVVLVDGNNKIRDIISYEPPHTVLLast
1 -75.900[H] COG0853 Aspartate 1-decarboxylase  ali  100  1MFRTMLGGKIHRATVTEADLNYVGSITVDQDLLDAAGIYPNEKVAIVNNNNGERFETYTIAGKRGSGVICLNGAAARLVQKSDIVIIMSYVQLSEPEIAAHEPKVVLVDGNNKIRDIISYEPPHTVL 127
2 -7.760[R] COG4857 Predicted kinase  ali follow..  7  1MMMGVTKTPLYETLNESSAVAL---------AVKLGLFPSKSTLTCQEIGDGNLNYVFHIYDQEHDRALIIKQAVPYAKVVGESWPLTIDRARIESSALIR-PRVFYSDTEMAVT............ 114
3 -5.610[K] COG2002 Regulators of stationary/sporulation gene expression  ali follow..  12  9..................RIDDLGRVVIPKEIRRTLRIREGDPLEIFVDRDGEVILKK..................................................................... 48
4 -5.590[O] KOG0739 AAA+-type ATPase  ali follow..  14  107..KKLQEQLMGAVVMEKPNIRWNDVAGLEKEALKEAVILPIKFPHLF---TGKRWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKELARQHKPSIIFIDEVDSLCGSRNENESEA.. 243
5 -5.450[J] KOG2523 Predicted RNA-binding protein with PUA domain  ali follow..  14  90YPTVQVDRGAIKFVLSGANIMCPGLTSAGADLPPAPGYEKGTIVVINAENKENALAIGELMMGTEEIKSVNKGHSIELIHLGDPL.......................................... 175
6 -5.420[S] COG5223 Uncharacterized conserved protein  ali follow..  16  5.FKNAGQRKNHRERAQPFERRKWGLLEKRKDYAQRAQDYKTKQKKLKRLRNPDEFYHEMTHKKTKNGV-TIDMDTIKILKTQDIGWIRHHRNVERAKIDHLEQQMHTVGAHRN.............. 129
7 -5.400[S] COG3915 Uncharacterized protein conserved in bacteria  ali follow..  11  33FSLQELATELPAVSFIHGSHRFTGFKV--SDLLEYLQQDHVKSVTFMALND------YAANISIAD-AYYMDGNEMKIRHKGPFWLVYNLDQNPKLKNSVYYTHMV..................... 143
8 -5.360[S] KOG4192 Uncharacterized conserved protein  ali follow..  15  19......ASRNHRC-LTGTNFFPVGFITVREVVEHKKGLL-----SFFDVLAGRKLGS---SGAHGTKCLSDSFLAIMARPAGNMTSMAALLSMASGFPASFR......................... 106
9 -5.260[P] COG0490 Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels  ali follow..  12  85........................DLIIEWCKAEAGAPAIHQTIGDLNVGQ--EYHVTVIAIVKKNQDKQLNPSSETVIDEGDTLVISG...................................... 147
10 -5.210[S] KOG3237 Uncharacterized conserved protein  ali follow..  11  8.SKKLSGQRQHRERSQPEARRKYGELEKKKDYKLRAEDYQKKRDTIKKLKNQDEYHHHMVNSETWADG-TETQIQKKLGSLKDLEYVKFKLNEEKKKIDEMKGELHFADSSLN.............. 135
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.