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Query: [KG] COG1349 Transcriptional regulators of sugar metabolism, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKPRQRQAAILEHLQKQGKCSVEELAQYFDTTGTTIRKDLVILENAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKALIAAAAVKYIHDGDSIILDAGSTVLQMVPLLSRFSNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENAFEQFSFDKLFMGTDGIDLNVGVTTFNEVYTVSNAMCNAAREVILMADSSKFGRKSPNVVCSLETVDKLITDAGIDPAFRQALEAKGIEVIITGESNELast
1 -96.200[KG] COG1349 Transcriptional regulators of sugar metabolism  ali  100  1MKPRQRQAAILEHLQKQGKCSVEELAQYFDTTGTTIRKDLVILENAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKALIAAAAVKYIHDGDSIILDAGSTVLQMVPLLSRFSNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENAFEQFSFDKLFMGTDGIDLNVGVTTFNEVYTVSNAMCNAAREVILMADSSKFGRKSPNVVCSLETVDKLITDAGIDPAFRQALEAKGIEVIITGESNE 257
2 -39.500[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  9  11LINDYDMLRVLKHFTIAHVDYAKNITRYTEIPQMRVREYLKRLKDLGLLDYYTNTSIKRTEKHHTYYQINKKAEAVLKEITPKLYVHHLKSADLQMLCSRKERKENPEACSSLLRMGLIDKCYDLTDLGRE---VFDTARRMQILHCEDRN.......................................................................................................... 168
3 -31.200[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  18  14MDTLKRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQENIISPSREGAILTPDFIEEQIIADAEKVLEEATKIAEDVRKMLEK...................................................................................................................................................................... 106
4 -13.900[K] COG2345 Predicted transcriptional regulator  ali follow..  13  13.GDGDTRRKILLILLERAPVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAA............................................................................................................................................................................................................. 63
5 -13.800[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  11  6..VFARRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIELNFVQDG......................................................................................................................................................................................................... 59
6 -13.400[K] COG4190 Predicted transcriptional regulator  ali follow..  18  66.TLTPRVLELIEAIRQEEPASINETARVVDRDVKNVHEELSRLAHLGIIFFEEDG.......................................................................................................................................................................................................... 119
7 -12.900[K] COG1654 Biotin operon repressor  ali follow..  20  1MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLRDWGV................................................................................................................................................................................................................. 48
8 -12.700[K] COG2378 Predicted transcriptional regulator  ali follow..  13  20MRKASRLFEIIQILRARRPVTAQTIADMLEVTARSVYRDIAALQTMRVIEGERGVGYILRPGFNLP---PLMFSIEETEAIVLALAMVDRSGDAELRQAAKKVSKIAASLPEPLSKTLSANALHAWGSIAPAPAGIDLATVRRAVRDEESDESGVETQRRIRPIAV........................................................................................... 191
9 -12.600[G] COG0120 Ribose 5-phosphate isomerase  ali follow..  20  3...................................................................ERNTSTDSPEKRAAGIAAAGLVSSGMLVGLGTGSTVAYTIKELGRRLDILGVVTSYQSEMLAIE---------------------AGIRLTTLAQHPELDLAIDGADQIDSELRAIKGGGAAHTREKIVVSARRFVVVADESKT.............................................. 131
10 -12.500[K] COG3355 Predicted transcriptional regulator  ali follow..  30  31........EVLHILLQNGKMTTDDLSQKLNVTKASISKALNNLLDKGLIQR.............................................................................................................................................................................................................. 73
11 -11.700[K] COG1777 Predicted transcriptional regulators  ali follow..  20  11AIENSTRREIIRMLTQFERSYALELSRSIGLSQQAILKQLEMLERANLVTSIGFV.......................................................................................................................................................................................................... 65
12 -11.600[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  8  106VFENSNRARIYEYIKTRPGAYLSEIIEKAGIDRGAARYHIKILKAHHKIEAYRESGKTRYFQNNSTYGEEEKKVVSAQNATNQRIISEIQNGKALAREIGVSRATISWYVKNLKETGLIDET....................................................................................................................................... 233
13 -11.000[G] KOG3075 Ribose 5-phosphate isomerase  ali follow..  16  1........................................................MAAGVPKIDALESLGNPLEDAKRAAAYRAVDKFDDHKIIGIGSGSTVVYVAERIGQYSKFICIPTGFQSRNLILD---------------------NKLQLGSIEQYPRIDIAFDGADEVDENLQLIKGGGACLFQEKLVSSAKTFIVVADSRKK.............................................. 148
14 -10.800[J] COG4901 Ribosomal protein S25  ali follow..  18  44VLDEKVFQAIAKEVQNMRVITPYEIASKYGIKMSVAFKVLRNLKERGDLVLVAKG.......................................................................................................................................................................................................... 98
15 -10.800[K] COG2188 Transcriptional regulators  ali follow..  16  13...EKVKDYILANIGTRKLPSENELVASLGVSRMTVHRALRELTAAGFLIRLQGGTFIAPPRPQSTLIEINNIAAEIVERGNRHRSEVLV-ALSFEFPKRVAIYHSVV..................................................................................................................................................... 133
16 -10.600[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  11  19.LKKNEIRIYRLLVEKRRGMRIREIQRELGISERSVRTHVLNLYRRGLLKRE............................................................................................................................................................................................................. 69
17 -10.500[K] COG1497 Predicted transcriptional regulator  ali follow..  13  7KGELTRFQILSEIAMRQPYVRQKDIADKLGVTVQAVSENIKSLIAEGLVESGSGRSHYK-MDLRRYADEVLESMSFYRSVWPAIAWEDLQEGDKVELFMEDGILYARRRRNGEAYAEVLHPA-ELGGTIPLQRGKVTIAVLPGISEGGSRNA----DLERLRELSRGHDRTGIMGTVSRAAANKLNLQVDFEFATPHAA------LAAAKRGLNVL-----------VLAVGKMSRSITEKLEKEGVEYSVED.... 258
18 -10.200[K] COG1725 Predicted transcriptional regulators  ali follow..  22  36....................SVREMGVKLAVNPNTVSRAYQELERAGYIYAKRGGSFVTS--------DKALFDQLKKELADAITERFLEEAKSIGLDDQTAIELLIKRSRNHE............................................................................................................................................... 122
19 -9.530[K] COG1420 Transcriptional regulator of heat shock gene  ali follow..  12  1.MLTERQLLIFRAIIDHFTWTIQPVGSKLPYSSATIRNEMGVLEEYGFIEKTHSGRVPSEKGYR-YLLQPKKLDKSDRQMIRSFFSENYYEMEGLIQNSALMLSDLTNYTSILLGPEATKNHLSGFRFVPINNFQAMLILIQGHVDNHLVTIPEGTTLSDIERMVLNERLVGLSLDDLKVQIPMEGKHVRNYESFMHVFSDSFAQASQQKVYFGGKTNILDINKVREMLHLMEEEQDVYELFRDDGLQVKIGRENN. 284
20 -9.490[K] COG1414 Transcriptional regulator  ali follow..  14  16..ALDKGLDILELLASVDGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKL------GLAQLHAPVRRLASFATPFMRE--------------LADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREMMI....................................................................................... 165
21 -9.480[K] COG1846 Transcriptional regulators  ali follow..  17  44......EIHTIDAIGTDEGLLMKELAERLGVTKGAVSQLVDRLEAKALVRR.............................................................................................................................................................................................................. 88
22 -9.460[K] COG1438 Arginine repressor  ali follow..  12  5AKQEELVKAFKALLKEEKFSSQGEIVAALNINQSKVSRMLTKF----------GAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEA............................................................................................................................. 147
23 -9.430[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  17  248....PELCEVLDIIRGHGRITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLRNG.......................................................................................................................................................................................................... 299
24 -9.420[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  21  2...KMKTLFLLIKLAKMGAVTMRELSRELDVSPQTVLRWLEELKEQGYIHKRESR.......................................................................................................................................................................................................... 59
25 -9.410[F] COG0528 Uridylate kinase  ali follow..  10  1MAQISKYKRVV--LKLSGEALAGEKGFGINPV-KSVAEQVAEVAKMDCIAVIVGGGNIWRG--------KTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFST--DTTAALRAAEVEADVILMGKNNVD---GVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK.... 240
26 -9.300[K] COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain  ali follow..  11  1MGRINELRMISRVMYFSEHKRQAEIAQHLNLSQATVSRMLKRAEAEGIVRTSIIPPPGTYSDLEAQLREREDRDGAIMARIGEAAAHFLSQNEIIGVSSSQTIFKMVENIHPLKGA----------------KARYIVQTLGGMGDPSVQTHATQITTRLARLTEAEPKLLPVPGVATSREAKLLMLADPFVRETIDLFGSITLAI................................................... 209
27 -9.200[K] COG4742 Predicted transcriptional regulator  ali follow..  20  9VFRSQKRRDLLLLL-GEEPRTMEDIKVLLDVSPTAILPQIKRLTDSNLVIQKNGSYELT...................................................................................................................................................................................................... 66
28 -9.160[J] KOG1767 40S ribosomal protein S25  ali follow..  12  42LFDQATYDKLLTEAPKFKLITPSILSDRMRINGSLARRAIRELMAKGVIRMVAAH.......................................................................................................................................................................................................... 96
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]