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Query: [L] COG1533 DNA repair photolyase, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRIRPDRNRGRSAGINPSGRFEPVSRHVFDDGWSSLEELPPFKTEVQVEKPRTIITRNESPDISFDRSINPYRGCEHGCVYCFARPTHAFMGLSPGLDFETKLFAKPDAARLLDKELSKEGYQPRTIAIGTNTDPYQPIEKQYRIMREILEVLEARGHPVGIVTKSALVTRDIDILSRMAERGLAKVALSVTTLDRMLARTMEPRASTPTKRLEAIRQLSDAGIPTSVMVAPIIPGLTDQEMERILDSAYAAGAREAGYVVLRLPLEVSPIFKDWLLRHYPDRYRHVMSLIRSMRDGKDYDSEWGKRMKGAGPYAWQIGRRFEITAKRLGLNIERRTLRTDQFVAAGKDQEQLMLLLast
1 -110.000[L] COG1533 DNA repair photolyase  ali  100  1MRIRPDRNRGRSAGINPSGRFEPVSRHVFDDGWSSLEELPPFKTEVQVEKPRTIITRNESPDISFDRSINPYRGCEHGCVYCFARPTHAFMGLSPGLDFETKLFAKPDAARLLDKELSKEGYQPRTIAIGTNTDPYQPIEKQYRIMREILEVLEARGHPVGIVTKSALVTRDIDILSRMAERGLAKVALSVTTLDRMLARTMEPRASTPTKRLEAIRQLSDAGIPTSVMVAPIIPGLTDQEMERILDSAYAAGAREAGYVVLRLPLEVSPIFKDWLLRHYPDRYRHVMSLIRSMRDGKDYDSEWGKRMKGAGPYAWQIGRRFEITAKRLGLNIERRTLRTDQFVAAGKDQEQLMLL 356
2 -18.100[R] COG1242 Predicted Fe-S oxidoreductase  ali follow..  14  24........................................................REEFGQKTYKVALDGGFDCPNGCTFCSAAGSGDFAGNRALD-------LKVQFQQVRDKMQTKWKDGKCIAYFQAFTNTHAPVAELREKFETVLNE-----VGLSIATRPDCLPDDVEYLAELNERTYLWLELGLQSAHDETGRLIN-RAHDYDCYLEGVRKLQKHNIRICTHIINGLPKETPEMMMETAQKVVESGVDGIKIHLLHLLKGTKGDLEFLTRDGYVNLVADQLEILPPEMVIHRITGDGGVDDLIGPVWSLNKFEVLNAIDAEL........................... 302
3 -17.400[R] COG1244 Predicted Fe-S oxidoreductase  ali follow..  12  24........................................................................IGCYRPCYMCSYPAQAPKKTSQER--------ILSHFLEAVHKIKGKDDRFSIRIFTSGSDSAEVRRDTRIRIFREISK--LDNVYEVVVETRSEIIREDVRELAEMVEDKWFEVAIGLESANDDIADVSINKGSTFNDFVRASEIIHNAGAKVKTYLLLKPIFLSERDAIEDVKFSAEPYTDTFSINLTNIQKGTLYESLWQRGEYRTPWLWSVVEVLRWAKKKPVGAGSARGPHNCGGSKDKAIERAIRKFSATQDLKFLEVEENCLEEWEYIKSEGLLDW. 316
4 -17.100[R] COG2108 Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme  ali follow..  15  40...................................................................VLFVTGVCPRNCFYCPLSPWRRKDVVYANE-------RPVRSEKDIIEEAKIQDARGAGITGG---DPLARLSRTVEYI-RLLKEEFGKKFHIHLYTTGILASE--EALEKLYDAGLDEIRFHPDL--------FQPNSKFFEREIENMKKAFDFGWDVGGEV-PAVPG-FEDRIKWFASLLDKLGAKFLNINELEFSETNLRALLD.................................................................................. 223
5 -16.800[S] COG1856 Uncharacterized homolog of biotin synthetase  ali follow..  15  68........................................................................RNCELMCDHCASKILWHMIPATTPEELVKVG-----------EDLKKKGIEGVLISGGSDKNGFVPLW-------DFFDAMKYLKEELGFLLTCHVGLVDEDYVEKLKEANVDAVLLDIIGDNETIAQVYKLPHKSVEDYDRSLRLLKEAGLRIVPHVIIGLHYGKIKGEYNAIDMIAKYEPDALVLVVV.............................................................................................. 239
6 -15.400[S] COG4422 Bacteriophage protein gp37  ali follow..  14  2............RITEMADRVSRTGIGKLAGASHQLHTLNTNERDNSAMAETSI---------WTDATWNPVAGCTAGCTNCYAMRMAARLEAMGTEKYQGLTRKTGGRAK--SLAIPATWSKPRRVFVNSMSDLFHV-DVPADFIRQVWTVMEETRHTYQILTKRPEVMASVLTRGEFPVLSNVWLGTSVEDSRV-------------LSRLDDLRRVPAS---RFVSLEPLIGSVAGANVDEIEAMCRRSGTAFFF.................................................................................................. 259
7 -15.100[R] COG2516 Biotin synthase-related enzyme  ali follow..  10  2........................................RVRLSYGTAVSMGLIRAKLLARPTTAYLMTYYEGCINDCKFCAQAR-----SSRANLEMLSRVVWPAFELETVLKNFSKGNFKRICLQTIDYPNMLSDVF-------SLLEELSKLNVPISL----SITPVPRSELEEFSTLGVDYIGVGLDAASERVYKDVKISRYSWDDMWKFFDDVLSVFGKGRAVVHLIV-GETDKEIVETIGEVYKKGGIVSLFAFTPIKGT--------MENFSPPPLERYRKIQV................................................................ 232
8 -14.600[KB] COG1243 Histone acetyltransferase  ali follow..  15  2.....................................................QVIRKPTRMLSGVTIVSIMTSCPHGCVFCPGGVDVDTPQSYYGRE--RAIENDYDPFHQVQSRLRQYVENGHELIIMGGTFLSLPIDYQDWFVTYALEAMNRFPVGMTIETKPDWA--KEWHADQMLRLGATKVELGVQTVYDDILKFTN-RGHTVKDSIESTRILKDSGFKVVYHVMLGLPKSDPDKDLEAFKTIFSDRPDMLKIYPTLVVETARGLYKPYGTETLIELISEMYRYIPKWVRVMRIQRDIPANVILDGNKKGNLRELVEKKVLEKGIKIN...................... 324
9 -14.300[R] COG5014 Predicted Fe-S oxidoreductase  ali follow..  12  84.........................................................................GCKFLCAYCWNY------FRNLRPKRAGDFLSPEEVAERLLEISKKRKCDLFRI---SGAEPILGRR----SAEHVRKVIELVNNTFILETNGLMFGFDPSLVDLFVN-LNVLIRVSVKGWDEESFEKITGASGEYFR--YQLKALEHLHGKVHFWVAVVYDLFREKGLKELEKRLP.......................................................................................................... 244
10 -14.200[R] COG1964 Predicted Fe-S oxidoreductases  ali follow..  16  104....................................................................IVLTNRCDLACWYCFFYARRAGYVYEPTI---------EQIREMVRKAKNMKPIGCNAVQLTG-----EPTLRD---LIDIIRMIKEEGYDIQLNTNGIRLAEDPDFALRVRVAGVNTVYLSFDGVDEKTNPKN-------HEIPKILENCRRAQLGL-VLVPTVIKGVNDHQLGDIIRFAAENIVRGVNFQPVSLVGSMPRKEREQFRITIPDCIKAIEE................................................................... 305
11 -14.000[C] COG0731 Fe-S oxidoreductases  ali follow..  11  88...................................................................QMTPTLICNQRCLFCWRPTEVPVPAPGEWDSPEKIVEESIASPNALRERWLEGNEPNNVAISLSGEPTFYP-------LPELIEEYEKRGFTTFLVTNGTVP----SMLAKVNP-SQLYMSLDAPD-LKTYLRVCQPKSPALWDRIESLDIMKDKCSRTVIRTT-LVKGENIFNPKGYAELIKRASPDFVEIKAYMHLGFSRLRLDRSAMPTHEEVLEFSKEL.................................................................. 309
12 -13.200[R] COG2100 Predicted Fe-S oxidoreductase  ali follow..  20  119....................................................................VRGSTGCNMRCIFCSVD------EGPYSRTRKLDFVVDIDYLLKWFDWVAKEKGKGLEAHLDAQGEPL--------LYPFIVELVQALR-VISMQSNGVLLND--KLVEELAEAGLDRVNLSIHSLDPEKAKMLM-KDYDLNHVLEMAEALVNAGIDVLIAPV-IMFGVNDDEAEAFIEFARRIGAG..................................................................................................... 294
13 -13.100[R] COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)  ali follow..  13  4..................................................................TAKPTSYQCNLKCDYCFYLSKENIFQHKGWMTEET-------LETFIERYISASGHDVYFTWQGG-----EPTMAGLDFFEKAIQYQNRYKIHNALQTNGILLDDACLFLRE----NHFLVGVSIDGPKEDRYRVTRSGKGSFDKVMAGIEQLKKHQVEFNTLT--VINRINVKYPLEVYRTLKSIGAKHI................................................................................................... 183
14 -12.700[C] COG1032 Fe-S oxidoreductase  ali follow..  9  245...................................................................MVEVMRGCGVGCDFCEVTLRP----------------LRYMPLNMIVDEIKINVAGGNAWLHSDEIFGYKHGHFNEEALSELFSTVMSVP-RISIPAGYPEMMEKLSKILKAGPRNWIGIQTGLETGSEELAKKHMPNKTLPDIVWQGVFVETRNYWRSAFTIQVGQEGETPEDLWETIALINKLSNSYV................................................................................................... 442
15 -12.300[R] COG0535 Predicted Fe-S oxidoreductases  ali follow..  17  12...................................................................DFNLTNGCNLACSHCHSASGPKLDN-----------ELKTEEILQTIDALHIIGALKIAFAGG---EPF--------IRRDIFNILSLPGWGISVITNGFYLNSLT-VEKLKAQCPNLSINISVDGSTPAGYSTLRKQLNRPDADLSGIDNVVRSGMSNSVNF--TITKATLHDIEATYELVVDRGADNMVAIKF.............................................................................................. 194
16 -12.200[BK] KOG2535 RNA polymerase II elongator complex, subunit ELP3/histone acetyltransferase  ali follow..  13  107..........................................................................TGNICVYCPGGPDSDFEYSTQSYTGYEPTSMRADPFLQTRHRVEQLKQLGHEFIVMGGTFMCLPEEYRDYFIRNLHDALSGHSIGITIETRPDYC--LKRHISDMLSYGCTRLEIGVQSVYEDVARDTN-RGHTVRAVCESFQLGKDAGYKIVTHMMPDLPNVDFERDIEQFIEYFENRSDGLKIYPTLVIRGTTGRYKSYPPSMLVDLVAKILALVPPWTRVYRVQRDIPMPLVSSGVEHGNLRELALARMKDLGTT........................ 399
17 -11.500[O] COG1180 Pyruvate-formate lyase-activating enzyme  ali follow..  15  79.......................................................................TYGCNWMCMYC--------------QNYDISQRRKAEGVELSPEEIVELAMGYDVDGMTTYNEPAIFSE----FAHDVGIVAKRYGLFNTMVSNGYWTPNLVDYVKDFLD----AVTIDFKGNGEQKFLRRYTGATSAEPIIETASELSKKGIHVEITD-LIIPQIGDQAAKQLLTKLYDQLGADIPIHFLRFHPDYK-------LNYIPWTPVETLERHYKLAKELGFKFVYVGNVPGHPYENTYCPNCGNLVIRRYSFDILEWHLTED............... 321
18 -11.300[C] COG1031 Uncharacterized Fe-S oxidoreductase  ali follow..  16  178....................................................................IEVSRGCERRCSFCTEPLLHGRLKSRDVQAILKEI-----------ESLYRAGCRAFRFGRAANILAFGSDRNGGKPSPEILEELYSNANPSYLVTYEKECRKIVETIVRYNTPGDV-FSFGVESFDENVLKKNN-VQGSPEEFLKAIAVVNEIGLLPGVNLIFGLPGETEETLKKNYSYLKRILDEGYLLRRINI............................................................................................ 386
19 -10.800[E] COG1509 Lysine 2,3-aminomutase  ali follow..  13  121....................................................................LLATDRCPVYCRFCTRS---YSVGLDTQSVLKKKVSPFQSRWDTILAYLRVTPVIADVVVSGG--DCFRLKPSRLLAIGMGLLSIPSIRR-IRFATKGLAITSDHKWTDALDAGRDQGVEISFHTHFNHPREITD-------YTIAAAELLFKRGIRMRNQ-SVLMAGVNDEVMKQLVKKLSDLHIQ..................................................................................................... 304
20 -10.700[H] KOG2672 Lipoate synthase  ali follow..  11  123...................................................................TIMLMGDCTRGCRFCSVKTSRRP-------------PLDPNEPENTAEAIKQWNLGYIVLTSVDRDD-----DLGANHIAKTIQKIKEKAPHILVEALTPDFSGRMDLVEIVAKSGLDVFAHNVETVEELTPFVRDRRA---RQSLSVLKHVKKTCPHLITKTSIML-GETDAEILTTLKDLLEHNVDVVTFGQYMRPTKRHLKVQEYVH---PKKFEYWKEV.................................................................. 328
21 -10.400[H] KOG2900 Biotin synthase  ali follow..  18  69..........................................................................CTEDCKYC---------AQSSRYNTGVKATKLMKIDEVLEKAKIAKAKGSTRFCMGSAWRDLNGRNRTFKNILEIIKEVRSMDMEVCV----TLGMLNEQQAKELKDAGLTAYNHNLDT-SREYYSKIIS-TRTYDERLNTIDNLRKAGLKVC---SGGILGLGEKKHDRV............................................................................................................... 221
22 -10.300[H] KOG2876 Molybdenum cofactor biosynthesis pathway protein  ali follow..  13  74....................................................................ISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGIDKIR------------TGGEPL--------IRPDVVDIVAQLQ-TIGVTTNGINLARLLPQLQKAGLSA---INISLDTLVPAKFEFIV-RRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKA-PGFQGQISFITSMSEHFCGTCNRLRITAD...................... 323
23 -9.770[R] COG1313 Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins  ali follow..  12  126.......................................................................FSGCNFRCVFC------------QNWDISQFRIGVEYLPEYMAIKIEKAFQLGARNVNFVGGEPTPNLPFILETLRYV-----RVPIPIVWNSNMYMSEEAMKLLDGVVD----IYLGDFKYGNDRCAMKY--KVPRYWEVVTRNFLLAKEHFRAEFLIRHLVPNHLDCCTKPILRWIAENLGREI---------------VNVMFQYRPEY-------------------KAIEYDEIARTLTLDEMREAEKITKKLGFKN....................... 333
24 -9.760[H] COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases  ali follow..  15  16......................................................................PW--CVQKCPYC---------------DFNSHAIPEQDYIAHLLQDLHQDRQR-HSIFIGGGTPSLFSAEGIHTLLSGVAQCL-PFQPDIEITLEANPGTAEAERFKGYVQAGVTRISMGIQSFNDDKLVRL--RIHNAQEAKSAVGFAKLSGLKFNLDLMHGLPNQTLEEALSDLQQAIALEPPHLSWYQLTIEPNT........................................................................................ 208
25 -9.600[H] COG2896 Molybdenum cofactor biosynthesis enzyme  ali follow..  17  29....................................................................VSVTDRCDFRCTYCMAEHM-TFLPKKDLLTLEELDRLCSVFIEKGVRKLR------------TGGEPL--------VRKNIMHLIGNLS-ELTLTTNGSQLARFAGELADCGVRR---INVSLDTLNPEKFRTIT-RWGDLSRVLEGIDAAQKAGIHVKINAV-ALKDFNDAEIPELIRWAHGRGMDVTLIETMPM............................................................................................ 207
26 -9.600[R] COG0820 Predicted Fe-S-cluster redox enzyme  ali follow..  11  77..................................SADGTIKWAMRVGDQDVETVYIPEDDR---ATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAA----REIGLEKETGRRPITNVVMMGMGEPLLNMKNLIPALEIMLD-FGLSKRRVTVSTSG------VSGLEQMIGQIDVALAISLHAPNDKLRSEIMPDRWNIEAFLEVVRRYIASSNANRGKVT-LLDHVNDEHAHELAELLKGTPCK..................................................................................................... 294
27 -9.590[R] KOG4355 Predicted Fe-S oxidoreductase  ali follow..  12  208....................................................................ISISTGCLNACTYCKTKHARGNLASYPIDE------LVDRAKQSFQEGVCE------IWLTSEDTGAY---TNLPTLLWKLVEVIPEGAMLRLGMTNPPYILEHLEEMAKILNHPRVFLHIPVQSASDSVLMEMK-REYCVADFKRVVDFLKEKTIATDIICG--FPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKK--QRTKDLSRVFHSYSPYDHKIGERQQV.............................................. 440
28 -9.420[O] COG0602 Organic radical activating enzymes  ali follow..  13  11......TLQGEGYFTGVPAIFIR------------------------------------------------LQGCPVGCAWCDTKHTWDSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGG--------EPCIHDLMPLTDLLEKSGFSCQIETSGTHEVR-VTVSPKVNMRGGYDVLSQALERANEIKHPVGRVRD---EALDELLATLSDDKPRVIALQPISQ--KEDATRLCIETCIARNWRLS................................................................................................... 213
29 -9.190[HR] COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes  ali follow..  14  57....................................................................INYTNICLSKCRFCAFYAREKGYVLSHE--------------EILRKVGYAVKMGATQIMLQGGMNPDLGLEWFEELFRKIIHSLSPPEIVFLAKLERSSIREVLDRLKAAGLDSLPGGGAEILV--DSVRRKISPNKCSSDEWLRVMETAHSLNMPTTATM--FGHVESDGDIVEHLIKIRELQEKTGGFTAF.............................................................................................. 241
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 4 7 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.