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Query: [K] COG1654 Biotin operon repressor, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80
# Score Template Links and tools%idFirst MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLDADRIHSQLDSGNVAVLast
1 -45.500[K] COG1654 Biotin operon repressor  ali  100  1MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLDADRIHSQLDSGNVAV 83
2 -26.600[K] COG2378 Predicted transcriptional regulator  ali follow..  15  20MRKASRLFEIIQILRLAR-VTAQTIADMLEVTARSVYRDIAALQTMRVPIEGERGVGYILRPPPLMFSIEETEAIVLA..... 102
3 -15.400[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  20  4SPVFARRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIELNFVQDGRRH........................ 62
4 -15.200[R] COG1827 Predicted small molecule binding protein (contains 3H domain)  ali follow..  15  36LKILERDPARKSSLKRYESVSGIHSHWISGPDRESIDAVIDELKSEGILLGV-NLNDEEIKEVARKHGRLVEIIIKPEMSIVE 118
5 -14.900[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  14  14MDTLKRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQENIISPSREG............................ 68
6 -13.700[K] COG1522 Transcriptional regulators  ali follow..  16  4VELDKIDRKILEVLQSNGRLTNLEVAERVNLSPSPCLRRIRRLEESGV................................... 51
7 -13.000[K] COG1959 Predicted transcriptional regulator  ali follow..  26  12.....RALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGY-VTAVRGKGIRLGKPASAIRIGDVVRELEP..... 85
8 -12.900[K] COG4742 Predicted transcriptional regulator  ali follow..  19  9VFRSQKRRDLLLLLGEEP-RTMEDIKVLLDVSPTAILPQIKRLTDSNL---IQKNGSYELTDMGEQVFKK............. 75
9 -12.900[KG] COG1349 Transcriptional regulators of sugar metabolism  ali follow..  20  1MKPRQRQAAILEHLQKQGKCSVEELAQYFDTTGTTIRKDLVILENAGT................................... 48
10 -12.700[K] COG1497 Predicted transcriptional regulator  ali follow..  14  7KGELTRFQILSEIAMRQPYVRQKDIADKLGVTVQAVSENIKSLIAEGLVESGSGRSHYKITR..................... 68
11 -12.700[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  7  11LINDYDMLRVLKHFTIAHVDYAKNITRYTEIPQMRVREYLKRLKDLGL-LDYYTN............................ 64
12 -12.400[K] COG2345 Predicted transcriptional regulator  ali follow..  12  15...GDTRRKILLILLERAPVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAANPRQN.......................... 68
13 -12.200[K] COG4190 Predicted transcriptional regulator  ali follow..  18  68...TPRVLELIEAIRQEEPASINETARVVDRDVKNVHEELSRLAHLGIIFFEEDGQ........................... 120
14 -12.200[K] COG3355 Predicted transcriptional regulator  ali follow..  22  31........EVLHILLQNGKMTTDDLSQKLNVTKASISKALNNLLDKGL................................... 70
15 -12.100[K] COG1777 Predicted transcriptional regulators  ali follow..  22  15....STRREIIRMLTQFERSYALELSRSIGLSQQAILKQLEMLERANL................................... 58
16 -12.100[K] COG1414 Transcriptional regulator  ali follow..  21  14APALDKGLDILELLASVD-LTQAEIAKHLDRSPNEFYRMLDRLVKRGY-VTKLDGDRYSL....................... 73
17 -11.900[K] COG3711 Transcriptional antiterminator  ali follow..  17  2...NGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKLEQEGYPKLERTSQGNFI....................... 62
18 -11.900[K] COG2186 Transcriptional regulators  ali follow..  25  20........QIRELIDVGEFLPGTELAQKLGVSRPSLREALIALEIDNT-VEIRMGSGVYVST..................... 78
19 -11.700[K] COG2188 Transcriptional regulators  ali follow..  20  14....KVKDYILANIGTGRWGKDRELVASLGVSRMTVHRALRELTAAGF-LIRLQGVGTFIAPP.................... 77
20 -11.100[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  18  27.........YRLLVEKRRGMRIREIQRELGISERSVRTHVLNLYRRGLLKRELVQSGYTPVSPLEILQ............... 90
21 -10.700[K] COG1725 Predicted transcriptional regulators  ali follow..  16  14....QISDWMKKQMITGEWKGEDEMGVKLAVNPNTVSRAYQELERAGY-IYAKRGMGSFVTSDKALFDQLK............ 85
22 -10.500[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  17  2...KMKTLFLLIKLGKEITVTMRELSRELDVSPQTVLRWLEELKEQGYIHKRESRKGTLV....................... 64
23 -10.300[K] COG1802 Transcriptional regulators  ali follow..  27  20........VLRQAIMSGRFTPGEELCETLGVSRTSIREALRRLEAEKL-VSIVPHKGPIVASRQEAAELFALRGLLEG..... 95
24 -10.100[J] COG4901 Ribosomal protein S25  ali follow..  11  52........AIAKEVQNMRVITPYEIASKYGIKMSVAFKVLRNLKERGDLVLVAKGHRTEI....................... 103
25 -10.100[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  25  184..QNATNQRIISEIQNGKCNTNLALAREIGVSRATISWYVKNLKETGLIDETRSGR-YSINP..................... 245
26 -10.100[K] COG4189 Predicted transcriptional regulator  ali follow..  14  23....LIRVQILKLLHEANGLNVNEIAQRLALPQSTVSAGVAVLEEAGL-LRTETRKARKGSQKICFATCDELIVSF....... 93
27 -9.970[S] COG2964 Uncharacterized protein conserved in bacteria  ali follow..  13  186..NNAKNRQIVLNLYEKGIFAINQVADRLNISKHTVYLYIRQFKSG..................................... 233
28 -9.770[K] COG0640 Predicted transcriptional regulators  ali follow..  7  3.......................EITMQTQADQPKVSSNLAILSEARLVDSIQMGR-YRIAPE.................... 44
29 -9.660[K] COG4738 Predicted transcriptional regulator  ali follow..  12  32LNINRPVALTLACLSKGDEISSQRIEMVSGLRQPEVSIAMRYLRENEW................................... 79
30 -9.440[K] COG1510 Predicted transcriptional regulators  ali follow..  19  40............IYMNRKPMTLSELSEATGMSKTRMSQVVREMIDANI-AEKVFEKGVR........................ 85
31 -9.200[L] COG4584 Transposase and inactivated derivatives  ali follow..  20  1MISYEDYMEVQILRRQG--CSLRAIATETGMAVNTIRKYLVSGAPERKPREPVVGK........................... 54
32 -9.140[K] COG1846 Transcriptional regulators  ali follow..  22  46........HTIDAIGTDEGLLMKELAERLGVTKGAVSQLVDRLEAKAL................................... 85
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Veeramalai M, Ye Y, Godzik A. TOPS++FATCAT: fast flexible structural alignment using constraints derived from TOPS+ Strings Model. BMC Bioinformatics. 2008 Aug 31;9(1):35