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Query: [K] COG1675 Transcription initiation factor IIE, alpha subunit, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKAETTTGVEELLNELVGRAAGEVGLILFSLGIEGEFTDDQLSLELGIEINEIRKALFALYEIGLADYVRRRDDETGWMEYYWRINYDKALDVLKRELEKTAKKLREKIEAETSTIYYICPNMCVKVSYNDAMELNFTCPRCGAMLDYLDCSKAIEKIEEEVRRIEEILESLDKNSGLast
1 -78.400[K] COG1675 Transcription initiation factor IIE, alpha subunit  ali  100  1MKAETTTGVEELLNELVGRAAGEVGLILFSLGIEGEFTDDQLSLELGIEINEIRKALFALYEIGLADYVRRRDDETGWMEYYWRINYDKALDVLKRELEKTAKKLREKIEAETSTIYYICPNMCVKVSYNDAMELNFTCPRCGAMLDYLDCSKAIEKIEEEVRRIEEILESLDKNSG 177
2 -45.500[K] KOG2593 Transcription initiation factor IIE, alpha subunit  ali follow..  17  11...DNYTPKNNNQKKSAKNGSGIAVLVLDALTRRQWVREEDLAKELKLNTKQLRTILRYFEEQQFIMRVHRKEKSSAHMYSYCCLDYSQIYDVIRYKLHRMKKEFKDVLEDKDNVQEYGCPNCKRKIFFHCENCNGELVMECVVVDGSDNPRSRRDHLKDLLQNMEVRLKPLMDH.. 202
3 -28.800[K] KOG2587 RNA polymerase III (C) subunit  ali follow..  9  367..KSIISVAQKDEAVVMRRYGKEAFRMFRYLSQEGRVETDKIADAALTEKKDTPQFLLKMWKDGYLHMQKVTAPGMYTPFLLWKVNKLIVTTQMLDEMYHASLNLSLRLAHELEAEKELLLLPLDKLEGPLKERLK-------------KVKAKRLLLSSTMFKLDDAIMLFHDF.. 529
4 -15.000[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  19  23......................EIRIYRLLVEKRRGMRIREIQRELGISERSVRTHVLNLYRRGLLK--RELVQSGWLGYIYTPVSPLEILQKIKEHLMKSIEELERDLKNQTRS.............................................................. 113
5 -14.800[K] COG3355 Predicted transcriptional regulator  ali follow..  25  32..........................VLHILLQNGKMTTDDLSQKLNVTKASISKALNNLLDKGLIQREKAPAEKEERPNYIYWVEKERLYRKLEADLEKLAGTVKEALQKHTALEIVI.......................................................... 127
6 -14.600[K] COG4738 Predicted transcriptional regulator  ali follow..  18  18MGEVEYEMVELLRRL---NINRPVALTLACLSKGDEISSQRIEMVSGLRQPEVSIAMRYLRENEWVDMREEKKNHRPVKLYKLTVQMETIIDTIEENVIAESKTILQNIERLKS............................................................... 131
7 -12.900[K] COG2345 Predicted transcriptional regulator  ali follow..  18  1MGDVVKGNDAHTGDGDTRR------KILLILLERAPVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAANPRQNPYEP................................................................................................... 72
8 -11.900[K] COG4190 Predicted transcriptional regulator  ali follow..  9  60............YDDLMDTLTPRVLELIEAIRQEEPASINETARVVDRDVKNVHEELSRLAHLGIIFFEEDGQRK...................................................................................................... 122
9 -11.600[K] COG1777 Predicted transcriptional regulators  ali follow..  17  1MIDDIDNFIAAIENSTRRE-------IIRMLTQFERSYALELSRSIGLSQQAILKQLEMLERANLVTSIGFVPSSVGAKRKLY.............................................................................................. 76
10 -11.300[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  23  18.....................KRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQENIIS.............................................................................................................. 63
11 -11.200[K] COG4189 Predicted transcriptional regulator  ali follow..  12  1MAPNFLLVDAEKEFDVLKAAASLRVQILKLLHEANGLNVNEIAQRLALPQSTVSAGVAVLEEAGLLRTETRKARKGSQKICFATCDIVSFRKPETPAASNYIAVAMPLGLYTQSSVTAPCGICSPEIGLLDVPDTFMDPDRMKTALVEYQFPNNAKIQGRNVEEIEFSMEVSSEVPG 189
12 -10.700[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  18  1MSEYEKEIDELIND-------YDMLRVLKHFTIAHVDYAKNITRYTEIPQMRVREYLKRLKDLGLLD.............................................................................................................. 60
13 -10.500[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  17  2..........ELSPVFARRL-----YLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIE............................................................................................................... 52
14 -10.300[K] COG1846 Transcriptional regulators  ali follow..  11  47..........................TIDAIGTDEGLLMKELAERLGVTKGAVSQLVDRLEAKALVRRTAHPKVSRGIQVVL-----REAYRAHADMHAAFYEELQQSFTKEE................................................................ 132
15 -10.000[K] COG0640 Predicted transcriptional regulators  ali follow..  18  3........................................EITMQTQADQPKVSSNLAILSEARLVDSIQMGREK------IYRIAPEKFEDMVD.................................................................................. 51
16 -9.980[K] COG1378 Predicted transcriptional regulators  ali follow..  14  19FVVTMDEIIEVLKRL---GFRDYEARVYATLATRGEATASEIHRVSGVPRNKVYEVLRSLEDRGMIETIKSSPA------VFRAIDPESVLEEYKEQLVSAVDTAIRSIRESEDFS............................................................. 125
17 -9.750[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  24  4......................KTLFLLIKLAKMGAVTMRELSRELDVSPQTVLRWLEELKEQGYIHKRESRKGT...................................................................................................... 62
18 -9.570[J] COG2888 Predicted Zn-ribbon RNA-binding protein with a function in translation  ali follow..  20  1........................................................................................................MSVKLSIREEVEPPICSSCGKIIH-PREKGVEFYCPNCGEVLIR............................. 43
19 -9.570[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  16  228.IEPAGNPDIETAALNRIPLSPELCEVLDIIRGHGRITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLRNGREN...................................................................................................... 302
20 -9.320[K] COG1510 Predicted transcriptional regulators  ali follow..  12  1MKKTALDIIEHAEEHLIEKIAEVGRVLGIIYMNRKPMTLSELSEATGMSKTRMSQVVREMIDANIAE----KVFEKGVRKDLYDVEQDYYQTFISLFAANWTKVVSKNKV................................................................... 116
21 -9.180[DR] COG5124 Protein predicted to be involved in meiotic recombination  ali follow..  15  10.....................QKKSILLEIIRGSKKLQEESLGSKKGIVVNTIKEILQQLVDDGLVTAEK------GTSNLYWSFASEG-----IQKKKLRCKELMEECERMSQDICRKREYIENEKMSKHYTE------------ERNELENKLNALMKIEQDQREELGKFEETD. 146
22 -9.180[DR] KOG3433 Protein involved in meiotic recombination/predicted coiled-coil protein  ali follow..  15  10.....................QKKSILLEIIRGSKKLQEESLGSKKGIVVNTIKEILQQLVDDGLVTAEK------GTSNLYWSFASEG-----IQKKKLRCKELMEECERMSQDICRKREYIENEKMSKHYTE------------ERNELENKLNALMKIEQDQREELGKFEETD. 146
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;