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Query: [K] COG1695 Predicted transcriptional regulators, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDRYAIKALVLLSKKPRTLYQMSKEISTGVQVSHGTLMPMIRKLLQERYIDFETRGREKVYHLTERGSRFVESLGKIEEDVKQNLISRTMGDAFFYLNLLSKNDTSEAIKSAIQILLPAIIAQVEYAFRMLMEGHREEVEGVARDLLRKYGEIDDEQSLSLast
1 -66.400[K] COG1695 Predicted transcriptional regulators  ali  100  1MDRYAIKALVLLSKKPRTLYQMSKEISTGVQVSHGTLMPMIRKLLQERYIDFETRGREKVYHLTERGSRFVESLGKIEEDVKQNLISRTMGDAFFYLNLLSKNDTSEAIKSAIQILLPAIIAQVEYAFRMLMEGHREEVEGVARDLLRKYGEIDDEQSLS 160
2 -17.600[K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family)  ali follow..  14  81LSPIEILILHSIRDREKKLADICLALD-----DTHIATYAIRKLEKAGLLTTGKAAKEKTVKITAKGAEACAHYAQIRERLLVDSTA----------NARPSEETLSELAALLRFMSGAFNQATRSAIT............................... 198
3 -16.400[K] COG3432 Predicted transcriptional regulator  ali follow..  14  38..EIMFDILRNCEPKCG-----ITRVIYGAGINYVVAQKYLDQLVKVGALNIKTENDRKIYEITEKGKLLRTHIEE.................................................................................... 106
4 -15.000[K] COG1846 Transcriptional regulators  ali follow..  10  40LTPSEIHTIDAIGTDE------MKELAERLGVTKGAVSQLVDRLEAKALVRRTAHPKVSQVVLTDKGREAYRAHADMHAAFYEELQQSF------------TKEEIAIFEQCVSKLRDILSE...................................... 149
5 -14.700[S] COG3373 Uncharacterized protein conserved in archaea  ali follow..  15  16.SELRRKVLFYLLSYRSYLSEISRAVKSDPSNVKGCLYTGEESLIGLGLVIVEQSKNGKYFKINPEIVEEVRNMKNMFSD................................................................................ 104
6 -14.500[K] COG4742 Predicted transcriptional regulator  ali follow..  20  12.SQKRRDLLLLLGEEPRTMEDIKVLLD----VSPTAILPQIKRLTDSNLVIQKNGS----YELTDMGEQVFKKARALVDVL............................................................................... 83
7 -14.200[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  21  1MKMKTLFLLIKLAKMGAIGKE-MRELSRELDVSPQTVLRWLEELKEQGYIHKRESRKGTLVELTEKGINLLEKLYEEISTALYS............................................................................ 87
8 -12.600[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  14  186..ATNQRIISEIQNGK------NLALAREIGVSRATISWYVKNLKETGLIDETRSGRSIIYSINPSYEPLIEK....................................................................................... 253
9 -12.300[K] COG1777 Predicted transcriptional regulators  ali follow..  10  14.NSTRREIIRMLTQFERS----ALELSRSIGLSQQAILKQLEMLERANLVTSIGFVPRKLYEPTGFSTLIVDYGRNFLMIQRIPLENDSERVSVSFDEAISKLESIQHHIEELTKKRTELVKKKDELMAAIKYQLEDEDPITREIVLEYLNTFDVEE... 172
10 -12.300[P] COG0735 Fe2+/Zn2+ uptake regulation proteins  ali follow..  13  6LTKNQSLVMGALSDGPMSAYTILDKLRDNGFRAPLQVYRALDKLLEYGLVH............................................................................................................. 58
11 -12.000[K] COG3327 Phenylacetic acid-responsive transcriptional repressor  ali follow..  15  1MSKLDTFIQHAVNAVPVSGTSLISSL-EGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESK................................................................................... 97
12 -11.700[K] COG1497 Predicted transcriptional regulator  ali follow..  16  12....RFQILSEIAMRQ--PYVRQKDIADKLGVTVQAVSENIKSLIAEGLV--ESGSGRSHYKITRRGAEKIKEAAMDLRRYADEV........................................................................... 88
13 -11.600[K] COG1733 Predicted transcriptional regulators  ali follow..  13  19LCT-TMVLMRELVAGSTRFNDLRRGVP---KMSPTLLSQRLKELELAGIVERKGEKGIFDYRLTEAGRD........................................................................................... 88
14 -11.400[K] COG0640 Predicted transcriptional regulators  ali follow..  18  1......................MNEITMQTQADQPKVSSNLAILSEARLVDSIQMGREKIYRIAPEKFEDMVDWLDSILH................................................................................ 58
15 -11.300[K] COG1510 Predicted transcriptional regulators  ali follow..  14  35....RVLGIIYMNRKPMTLSELSEATG----MSKTRMSQVVREMIDANIAEFEKGVRKDLYDVQDYYQTFISLFAANWTKVVSKNKVLYKKLNRELSDLLQRDGLTPEAEEKVNQLLNELKEWLHYYDWLSRLIEFFESEEVFRYVPKTKECSSLK.... 185
16 -11.300[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  10  13NDYDMLRVLKHFTI---AHVDYAKNITRYTEIPQMRVREYLKRLKDLGLLDYYTNTHHTYYQINKKAEAVLKEITPK................................................................................... 103
17 -11.100[T] KOG4603 TBP-1 interacting protein  ali follow..  9  11..GAAGILLRYLQERPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSD--ADLQVLDGKIVAL--------------TAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATN.. 152
18 -11.000[K] COG3355 Predicted transcriptional regulator  ali follow..  14  25LSKSDVEVLHILLQN---GKMTTDDLSQKLNVTKASISKALNNLLDKGLIQREAEKEERKGRPNYIYWVEKERLYRKLEADLEKLAG......................................................................... 111
19 -10.900[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  15  246LSPELCEVLDIIRGHK--GRITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLRNGRENILVLVDEEH............................................................................................ 311
20 -10.800[K] COG3682 Predicted transcriptional regulator  ali follow..  15  3ITAAEAHVMEALRRSPLSADELVAEVGAAQSWGEATVKTLINRLLKKKAIKSERAEGKHGYRPLVDRSAYVQAESQGL.................................................................................. 81
21 -10.500[K] COG4190 Predicted transcriptional regulator  ali follow..  13  67LTPRVLELIEAIRQE---EPASINETARVVDRDVKNVHEELSRLAHLGIIFFEEDGQRKRPVVW................................................................................................ 127
22 -10.300[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  11  11.....LYLALLVESLERPN---VPKLIEKTGWPRRTIQDVIKAMPGIGIELNFVQDGRRYYQLSDWGPFDSQWVTERKKDIAASL........................................................................... 91
23 -10.200[S] COG2469 Uncharacterized conserved protein  ali follow..  16  197LSEVEEQILTMVYTGVDS-----VSVESILGVTTEELNKMYDRLVNLGLA--RVVKIRKEIELTPRGVALVSEIMKKAAR................................................................................ 269
24 -9.660[S] COG4860 Uncharacterized protein conserved in archaea  ali follow..  20  23.SEVKRKLLLDLSTGWITLPVIEQKYGK-------EGRRALLYLDKIKMIETQQNGPEKAYHTYYT.............................................................................................. 84
25 -9.530[K] COG2345 Predicted transcriptional regulator  ali follow..  16  15.GDTRRKILLILLER---APVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAANPRQAKTYRLTDKGRSIFGHEYDSL.................................................................................. 99
26 -9.490[K] COG1378 Predicted transcriptional regulators  ali follow..  8  42......VYATLATRGEATASEIHRVSG----VPRNKVYEVLRSLEDRGMIETIKSSPAVFRAIDPE--SVLEEYKEQLVSAVDTAIRSIRESE------DFSTLHPVWCVRGLAGIKNRAKAMLQRSEEV.............................. 153
27 -9.360[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  18  20....HISVINVLLREQPIG---IIKLSQETGIPEHKIRYSLRILEQENIISPSREGA----ILTPDFIEHKEQIIADAEKVLEEATK......................................................................... 95
28 -9.240[S] COG1693 Uncharacterized protein conserved in archaea  ali follow..  10  9TNQKMMEILRILAEDVLGAKIIASELRKKYNLGERAVRYHMRILDEKGFTERVGYAGR---RITEKGLQEINR....................................................................................... 81
29 -9.090[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  11  19LKKNEIRIYRLLVE--KRRGMRIREIQRELGISERSVRTHVLNLYRRGLLKVQSGWLGYIYEILQKIKEHLMKSIEELERDLKNQTRS........................................................................ 113
30 -9.000[K] COG5111 DNA-directed RNA polymerase III, subunit C34  ali follow..  9  83MEGDEQIVYSFIKNSGNEG---RKTLTLRTNLHVSVVDRCLKSLESKNLVKSVKNPTRKIYMLYDTGGPWFTDQEEFIENLKKVIYRYVHSKSFPPKKAAMGPDLVWGPEYNGYPTALQIHNWLRSTNITKVDLSLANVISLVDVL.............. 240
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;