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Query: [K] COG1709 Predicted transcriptional regulator, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVNINMFEKEKEILAKRIAGEIVLSPDPGKTMRKWREIFGISQTELADYLGVSSSVISDYEGGRRKSPGASTIRKFVEALIEIDEKRGGNVIKAFSRTFSSEIPTSAILDIREFDIPVTVKDIVDAVKGEIVANPDLIDRKIYGYTVVDSIQAILEMSAEEFLKLYGWTTERALVFTKVTTGRSPMIAVRVQGLKPAMVVLHGVKRLDELAVKIAEKERVPLVVSKAENETELITGLRRLVTSILast
1 -87.400[K] COG1709 Predicted transcriptional regulator  ali  100  1MVNINMFEKEKEILAKRIAGEIVLSPDPGKTMRKWREIFGISQTELADYLGVSSSVISDYEGGRRKSPGASTIRKFVEALIEIDEKRGGNVIKAFSRTFSSEIPTSAILDIREFDIPVTVKDIVDAVKGEIVANPDLIDRKIYGYTVVDSIQAILEMSAEEFLKLYGWTTERALVFTKVTTGRSPMIAVRVQGLKPAMVVLHGVKRLDELAVKIAEKERVPLVVSKAENETELITGLRRLVTSI 244
2 -28.300[K] KOG3398 Transcription factor MBF1  ali follow..  25  79.......................VPTELKKAIMQARTDKKLTQSQLAQIINEKPQVIQEYESG-KAIPNQQILSKLERAL.................................................................................................................................................................... 134
3 -27.800[K] COG4800 Predicted transcriptional regulator with an HTH domain  ali follow..  18  1..........MNVADKVIKSAFESDEVFQKTLAVIKEDLNLTAVDFAKKANIPPSTLYKILSGNRD-PNIKTLRQIVKTI.................................................................................................................................................................... 70
4 -26.300[K] COG1813 Predicted transcription factor, homolog of eukaryotic MBF1  ali follow..  17  105.......................IVEDYAERVMEAIRKSGLSYEELSHKVGLSVNLLRRIAHGEYT-PTIEEARKLERFFIKLVEKVEADFEQKPVIPRDYEPTLGDIARIKVKKKKKK............................................................................................................................. 200
5 -25.400[P] COG1513 Cyanate lyase  ali follow..  16  1MIQSQINRNIRL--------------DLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQA-LPADAARLVGAKLLDEDSILL............................................................................................................................................................ 74
6 -23.400[K] COG1476 Predicted transcriptional regulators  ali follow..  17  1...........................MKNNIKVYRAIHDLTQENLAEKVGVTRQTINAIEKG-KYDPSLDLAFKLSRLFASVEDIFLYESNEK...................................................................................................................................................... 67
7 -22.300[K] COG1396 Predicted transcriptional regulators  ali follow..  17  1...........................MSMRLKLLRKKLGVTLETLAEKTGLTKSYLSKVERG-LNTPSIAAALKLAKALVQVEELFSEESDGVDGYSIVRRDQRKSL........................................................................................................................................ 81
8 -21.600[K] COG1395 Predicted transcriptional regulator  ali follow..  21  124.......................YISIEGDLLKKARTDQSMSLGTLASMVGVSRRTISKYEEEGMD-ASIDVVLQLEDIFVELARPID............................................................................................................................................................ 188
9 -21.200[R] COG2522 Predicted transcriptional regulator  ali follow..  17  10................EYAAKNIFPSIRASIAKILVEEYKMSKYSVAKMLGATPTAVSYYISGKRGEKFVDRIIRDEEIYSIVREAASL........................................................................................................................................................... 82
10 -18.800[K] COG2944 Predicted transcriptional regulator  ali follow..  25  85............................PSEIKALRENNHVSQPVFARYLNTSESTVQKWETGAKR-PSGPALKLL........................................................................................................................................................................ 131
11 -17.800[S] COG5606 Uncharacterized conserved small protein  ali follow..  20  20..................AENMRIRAELVTIINNWIEQQGFSQAQAASALGVTQPRISELARGKIQIFSIDKLITMMAHA.................................................................................................................................................................... 81
12 -16.600[S] COG1426 Uncharacterized protein conserved in bacteria  ali follow..  18  1MNLLNEAQEQQ-------------LKEISKYLLQVRQEKGIRIEEVAAKTNIRLYFLQCLDAGKAELPE-GFIRRYADIL.................................................................................................................................................................... 72
13 -14.400[K] COG2932 Predicted transcriptional regulator  ali follow..  11  1......................MTMHETTDRLFEIAKEQGLKPADIAERLNISQQALKNWESRG---IAAKALPEVAKAFVSETWLRTGEGSRTAPVLIDPDLPHEV......................................................................................................................................... 84
14 -13.700[K] COG3655 Predicted transcriptional regulator  ali follow..  22  6..............................KLGVMMAERNVKSKDLAAYIGITEANLSLLKQGKVKGVRFETLEKICEFL.................................................................................................................................................................... 55
15 -12.800[S] COG4197 Uncharacterized protein conserved in bacteria, prophage-related  ali follow..  22  2..............................TLKEIKSLRVGDAKKFAARLGVSPSYLSQMASGRTA-ISPTRALMIESA..................................................................................................................................................................... 50
16 -11.200[R] COG3093 Plasmid maintenance system antidote protein  ali follow..  25  12............................GEMLKVFLEPMGITSKALAEAMGVHRNTVSNLINGGVLTAPVAI--KLAAAL.................................................................................................................................................................... 62
17 -10.700[R] COG2842 Uncharacterized ATPase, putative transposase  ali follow..  14  2..........................TLINKLKQHLSDSQITQAQLAREAGVNAGALSAYLNDNYKGNIADVEAKLAAYLEKKA------VQAREFVEAPAFIETATSRQIFKTLEFAQIANCLATVYGMSGVGKTKAIQEFAKSHANVWLVTASPSRSSLSEILYEIALELGISDAPRRKGTLSRLIARKIKGTEGLLIVDEADHLPEELRIMQEEAGIGLVLVGNDKVYTRMKGYARLWSRV 224
18 -9.410[K] COG5499 Predicted transcription regulator containing HTH domain  ali follow..  20  82.............................AVIRTLMDQYGLTLSDLPEI--GSKSMVSRVLSGKRK--TLEHAKKLATRF.................................................................................................................................................................... 129
19 -9.200[R] COG1342 Predicted DNA-binding proteins  ali follow..  23  36.....................VSLTVEELEALR-LVDIEGLRQEDAASRVGISRRAFWEDLKSARM--------KVAIALSK.................................................................................................................................................................. 87
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 4 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.