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Query: [K] COG1733 Predicted transcriptional regulators, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSQHGYKQFCPLSMAAEVLCTRWTMVLMRELVAGSTRFNDLRRGVPKMSPTLLSQRLKELELAGIVERKEVPGEKGIFDYRLTEAGRDLRPVVEAMGFWGQKWVESRLSLKNLDPSLLMWDMRRNLNPSPLPEGRTVIQFLYQDLPASKRSWWLIVEKHGEVDLCWYDPGFDVDLYVSTDLHTMTAIWMGLLTVEKAGGKVALTGDQAIGKKMQTWLGLSPFAVEPKRAALast
1 -91.300[K] COG1733 Predicted transcriptional regulators  ali  100  1MSQHGYKQFCPLSMAAEVLCTRWTMVLMRELVAGSTRFNDLRRGVPKMSPTLLSQRLKELELAGIVERKEVPGEKGIFDYRLTEAGRDLRPVVEAMGFWGQKWVESRLSLKNLDPSLLMWDMRRNLNPSPLPEGRTVIQFLYQDLPASKRSWWLIVEKHGEVDLCWYDPGFDVDLYVSTDLHTMTAIWMGLLTVEKAGGKVALTGDQAIGKKMQTWLGLSPFAVEPKRAA 230
2 -12.500[K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family)  ali follow..  8  66..SRWMVRCMAAAGLPGLSPIEILILHSIRHRDREKKLADICLALDIEDTHIATYAIRKLEKAGLLTTG---KAAKEKTVKITAKGAEACAHYAQIRERLLVDSTANARPSEETLSELAALLRFM......................................................................................................... 185
3 -12.500[K] COG3432 Predicted transcriptional regulator  ali follow..  22  34.....................RGTMEIMFDILRPKCGITRVIYGA-GINYVVAQKYLDQLVKVGALNIK---TENDRKIYEITEKGKLLRTHIEEFIK.................................................................................................................................... 109
4 -12.400[K] COG4742 Predicted transcriptional regulator  ali follow..  21  9.................VFRSQKRRDLLLLLGEEPRTMEDIKVLL-DVSPTAILPQIKRLTDSNLVIQK-------NGSYELTDMGEQVFKKARALVD.................................................................................................................................... 81
5 -12.100[K] COG1846 Transcriptional regulators  ali follow..  17  35............GRAGALTPSEIHTIDAIGTDEGLLM-KELAERL-GVTKGAVSQLVDRLEAKALVRRTAHPKVSRGIQVVLTDKGREAYRAHADMHA.................................................................................................................................... 118
6 -11.900[I] KOG4170 2-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/Peroxisomal 3-ketoacyl-CoA-thiolase, sterol-binding domain and related enzymes  ali follow..  13  14.......................................................................................................LQLQPKPRSGAVEETFRIVKDSLSDDVVKATQAIYLFELSGEDGGT---WFLDLKSKGGNVGYGEPSDQADVVMSMTTDDFVKMFSGKLKPTMASGKLKIKGNMALAIKLEKLMN............ 127
7 -11.700[Q] COG2015 Alkyl sulfatase and related hydrolases  ali follow..  10  445...........APKYVAAMGGMDNVIKLGKEAFDKGEFREIVDKAVFAEPS--NKQARYLQADCLEQLGYQSESAGERNTYLMGA----YELRNGVPKVSATKTAGADTVVAMDTELFLDYLGVRLNGDKAAGIDYTINFVLPD----VNEKFLVELENAHLNNLKGIQSENPDMTLTLNRAQLNQVLMGKTTIQQLEGKAKIEGNAQALTDIAGMLD............ 646
8 -11.600[K] COG1695 Predicted transcriptional regulators  ali follow..  13  1..................MDR--AIKALVLLSKKPRTLYQMSKEISQVSHGTLMPMIRKLLQERYIDFE---TRGREKVYHLTERGSR.............................................................................................................................................. 69
9 -10.600[S] COG3373 Uncharacterized protein conserved in archaea  ali follow..  12  9...........ILRSLNRSELRRKVLYLLSIYPYRSYLSEISRAV-KSDPSNVKGCLESLIGLGLVIVE--QSKNGFKYFKINPEIVEEVRNMKNMFS.................................................................................................................................... 103
10 -10.000[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  16  1MKQEEMLK--KLEDLLKAIGKKNEIRIYRLLVERGMRIREIQREL-GISERSVRTHVLNLYRRGLLKRELVQSGWLGYIYTPVSPLEILQKIKEHLMKS................................................................................................................................... 99
11 -9.670[K] COG1497 Predicted transcriptional regulator  ali follow..  16  2.............KALRKKGELTRFQILSEIAMPYVRQKDIADKL-GVTVQAVSENIKSLIAEGLVESG-----SGRSHYKITRRGEKIKEAAMDLRRY................................................................................................................................... 84
12 -9.580[S] COG4860 Uncharacterized protein conserved in archaea  ali follow..  10  1MVSRIVNDPGELVSIFHAADSEVKRKLLLDLSTGWITLPVIEQKY----GKEGRRALLYLDKIKMIEQWITGQNGPEKAYHTY................................................................................................................................................... 82
13 -9.410[K] COG3355 Predicted transcriptional regulator  ali follow..  15  19...........IAFMYGLSKSDVEVLHI--LQNGKMTTDDLSQKL-NVTKASISKALNNLLDKGLIQREKAPAEKEERKGRPNYIYWVEKERLYR....................................................................................................................................... 100
14 -9.240[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  16  177............KKVVSALQNATNQRIISEIQNGKNTNLALAREI-GVSRATISWYVKNLKETGLIDET---RSGRSIIYSINPSYEPL------IEKYG.................................................................................................................................. 255
15 -9.190[K] COG1510 Predicted transcriptional regulators  ali follow..  16  1MKKTALDIIEHAEEHLSTVGRVLGIIYMNR---KPMTLSELSEAT-GMSKTRMSQVVREMIDANIAEKVFEKGV-RKDLYDVEQ.................................................................................................................................................. 93
16 -9.130[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  12  10................ELINDYDMLRVLKHF-AHVDYAKNITRYT-EIPQMRVREYLKRLKDLGLLDYKSAEVHKHHTYYQINKKAEAVLKEITP....................................................................................................................................... 102
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.