current user: public
If you have questions about the server, please let us know.

Query: [S] COG2014 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .
# Score Template Links and tools%idFirst MNGMLLSRIKKKAMELAEDLKLVDFSFGLPYTWVLVEGIEGRALGVAMTLPEEVQRYTNSIEEPSLLEFIDKADSLNIIERTLGVAAINAVSQYYIDLREAKWIDVTELIQQDEIKRIAIIGNMPPVVRTLKEKYEVYVFERNMKLWDRDTYSDTLEYHILPEVDGIIASASCIVNGTLDMILDRAKKAKLIVITGPTGQLLPEFLKGTKVTHLASMKVTNIEKALVKLKLGSFKGFESESIKYVIEVLast
1 -85.700[S] COG2014 Uncharacterized conserved protein  ali  100  1MNGMLLSRIKKKAMELAEDLKLVDFSFGLPYTWVLVEGIEGRALGVAMTLPEEVQRYTNSIEEPSLLEFIDKADSLNIIERTLGVAAINAVSQYYIDLREAKWIDVTELIQQDEIKRIAIIGNMPPVVRTLKEKYEVYVFERNMKLWDRDTYSDTLEYHILPEVDGIIASASCIVNGTLDMILDRAKKAKLIVITGPTGQLLPEFLKGTKVTHLASMKVTNIEKALVKLKLGSFKGFESESIKYVIEV 248
2 -7.800[S] COG4378 Uncharacterized protein conserved in bacteria  ali follow..  15  2...................................................................................................................SSIMIVGHLGTIPKKLNEIGFSEIMHVTGRKVK------AVKKEIPSHVDLILVLTDYINHNLTSVLKKRASEQDIPICYAKRS................................................. 81
3 -6.990[C] KOG1494 NAD-dependent malate dehydrogenase  ali follow..  16  28.................................................................................................................PERKVAILGAAGGIGQPLA-VSSLSLYDIANTPGVAADVGDDNLAKALEGADLVIIPAAGIVKNLCTAIAKYCPHALINMISNPTVPIAAEIFKKAGMKKLFGVTTLDVVRARTFYAG................. 188
4 -6.810[C] COG1941 Coenzyme F420-reducing hydrogenase, gamma subunit  ali follow..  12  2.......................................................................................................EATKEAKPVANKIKLGHVGCLVSVADIYQG-----LLKILDDYADLVYALTLVDVRHIPEMDVALVEGSVCIQESVEDIKETRKKSRIVVALGSCATY--------NITRFCR................................ 110
5 -6.250[G] COG1023 Predicted 6-phosphogluconate dehydrogenase  ali follow..  12  2....................................................................................................................QLGMIGL-NIVRRLAKGGHDCVVYDHDPDAVKAGVASLRELSQRLSAPRVVWVPAGNITTAVIEELANTLEAGDIVIDGGNTDLRHEKLLFKKGIHLLDCGTSGGVWGRERCLMIGGDGDAFARAEPIFATV 153
6 -6.070[EH] COG0059 Ketol-acid reductoisomerase  ali follow..  8  32.............................................................................................................ANFLKGKKIVIVGC-LNQGLNMRDSGLDISYALRPEAIAEKRFKVGTYEELIPTADLVVNTPDKQHSKVVADVMPLMKKDSAFGYSHGFNIVEVGEEIRKDITVVMVAPKCPGTEVREEYKRGFG.............. 170
7 -5.880[R] COG1712 Predicted dinucleotide-utilizing enzyme  ali follow..  15  3....................................................................................................................KIGIVGICRAIDGGEVSAELYALCDSSESKALECKPSYMKIEELIRGVDLIIESASQNAVRFI--VPQALKAGCDVMILSVGALADEEL........................................... 103
8 -5.740[C] COG0039 Malate/lactate dehydrogenases  ali follow..  12  1.............................................................................................................MNKFKGNKVVLIGNYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATSDCHDADLVVICALKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLRVIGSGTILDSARFRLLLSE................. 162
9 -5.520[E] COG2066 Glutaminase  ali follow..  9  15..ADILASIIEEVRPLTSKGIVADYI--------ALAKVPSDKLGIAVFTNQGEVITAGDAQEGFSIQSISKVLSLTLAMGLYQPDELWSRVGKEPSGQAFNSLIQLEMEQGIPRNPFINAGAIVVCDMLQSRLSARQLSGEPQIAYDKVVAASEMMHSDRNAAIAYLMRSFGNFHNEVIPVLHNYFHACALKMSCVELAKTFSYLANKGVSVVTGETVITPTQSKQTNALLATCGLYDGAGEFAYRV 262
10 -5.500[R] COG3442 Predicted glutamine amidotransferase  ali follow..  13  3................................................................................................................SPQLELTIGWLYPTLMSTYGDRGNVITIERRAQWRGYTVLDQNSTADDIKSVDVIVGGGAQLQGAKADAMREKIDNGTPGVFTCGSPQLLGHYYEPAFGQRIEGLGILDLVSIHP..................... 131
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 8 0   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Zmasek CM, Zhang Q, Ye Y, Godzik A. Surprising complexity of the ancestral apoptosis network. Genome Biol. 2007 Oct 24;8(10):R226 [Epub ahead of print]