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Query: [K] COG2188 Transcriptional regulators, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIDLPDTASPLYEKVKDYILANIGTGRWGKDRKLPSENELVASLGVSRMTVHRALRELTAAGFLIRLQGVGTFIAPPRPQSTLIEINNIAAEIVERGNRHRSEVLVLETIMPTKELALSFEFPKRVAIYHSVVVNFENDLPVQLEERFVNPSLIPDYDKQDFSKTATYDYLMQKTPVTEVEHIISAIPADAETARHLNIDVGSCCLFLHRRTWTGAIVATISKLTYAGSRYSLGSRYSPSKTNLast
1 -101.000[K] COG2188 Transcriptional regulators  ali  100  1MIDLPDTASPLYEKVKDYILANIGTGRWGKDRKLPSENELVASLGVSRMTVHRALRELTAAGFLIRLQGVGTFIAPPRPQSTLIEINNIAAEIVERGNRHRSEVLVLETIMPTKELALSFEFPKRVAIYHSVVVNFENDLPVQLEERFVNPSLIPDYDKQDFSKTATYDYLMQKTPVTEVEHIISAIPADAETARHLNIDVGSCCLFLHRRTWTGAIVATISKLTYAGSRYSLGSRYSPSKTN 243
2 -33.400[K] COG1725 Predicted transcriptional regulators  ali follow..  27  1MNPTFHADKPIYSQISDWMKKQMITGEWKGEDKLPSVREMGVKLAVNPNTVSRAYQELERAGYIYAKRGMGSFVTSDKALFDQLKKELADAITER.................................................................................................................................................... 95
3 -30.100[K] COG2186 Transcriptional regulators  ali follow..  23  4.QAKIAEPRRLYQQIADQIRELIDVGEFLPGTRLPAERELAQKLGVSRPSLREALIALEIDNTVEIRMGSGVYVSTEALQTTHHTKSLGDSELMQARAALEGATIVLAANRMTDETIAALR.......................................................................................................................... 125
4 -23.400[K] COG1802 Transcriptional regulators  ali follow..  22  9......KPETLRYQVENVLRQAIMSGRFTPGERL-IERELCETLGVSRTSIREALRRLEAEKLVSIVPHKGPIVAIISRQE-AAELFALRGLLEGFAAREFAQRATDVAIVHFAQAIQALR.......................................................................................................................... 121
5 -21.400[KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs  ali follow..  36  4ISLDRAANSPLIQQVYMQIRKKILSGELMAAEKLPSTRQLADLLGISRNVVLEAYDQLLAEGFLVSKRGAGTFVAE....................................................................................................................................................................... 79
6 -11.700[K] COG1654 Biotin operon repressor  ali follow..  20  5.............TVPLTLISLLADGEFHSGE------QLGERLGMSRAAINKHIQTLRDWGVVFTVPGKGYSLPEP...................................................................................................................................................................... 63
7 -10.800[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  12  20...............HISVINVLLREQ--------GIIKLSQETGIPEHKIRYSLRILEQENIISPSRE-GAILTPD...................................................................................................................................................................... 74
8 -10.800[KG] COG1349 Transcriptional regulators of sugar metabolism  ali follow..  16  4............RQRQAAILEHLQK------QGKCSVEELAQYFDTTGTTIRKDLVILENAGTVIRTYG-GVVLNKEESDPPIDHKTLINTHKKALIAAAAVKYIH----------GDSIILDAGSTVLQMVP.............................................................................................................. 108
9 -10.600[K] COG3355 Predicted transcriptional regulator  ali follow..  24  43...................................TTDDLSQKLNVTKASISKALNNLLDKGLIQREK............................................................................................................................................................................... 75
10 -10.600[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  11  1............MELSPVFARRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPGIGIELNFVQDGRR.......................................................................................................................................................................... 61
11 -10.300[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  24  251............CEVLDIIRGH--KGRI-------TQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLRGRENILVLVDEEH.................................................................................................................................................................. 311
12 -10.300[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  11  107..........FENSNRARIYEYIKTR---PGAYL---SEIIEKAGIDRGAARYHIKILKAHHKIEAYRESGKTRYFQNNSTYGEEEKKVVSALQNATNQRIISEIQNGKCNTNLALAREIGVSRATISWYVKNLKETG......................................................................................................... 228
13 -9.640[K] COG0640 Predicted transcriptional regulators  ali follow..  13  3......................................EITMQTQADQPKVSSNLAILSEARLVDIQMGREKIIAPEKFEDMVDWLDSILHSKSSGGSANYGLSPVNDLNYARDHLAGEMGVYLLEELLKRKWIILDDPE....................................................................................................... 110
14 -9.470[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  29  7................FLLIKLAKMGAIGKEITV-TMRELSRELDVSPQTVLRWLEELKEQGYIHKRE............................................................................................................................................................................... 57
15 -9.380[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  10  33.....................................KNITRYTEIPQMRVREYLKRLKDLGLLDYYTNTSIKRTEAKLKKSAEVHKHHT-QINKKAEAVLKEITPKLYVH.................................................................................................................................... 107
16 -9.340[H] COG3161 4-hydroxybenzoate synthetase (chorismate lyase)  ali follow..  14  23...........................................................................PADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRADLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLS-GNPLLLTE.................................. 157
17 -9.120[K] COG1959 Predicted transcriptional regulator  ali follow..  17  1MQLTSFTDYGLRALIY----------ASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKGIRLGKPASAIRIGDVVRELEPLS..................................................................................................................................................... 87
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;