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Query: [R] COG2351 Transthyretin-like protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGRLTTHVLDTAAGTPGKDLAITLFKIVNNLRQPIKTVRTNHDGRCEAPLLEGEALQAGIYELDFAVGDYYRAAGVSLPDPAFLDVVTLRFGVADAGAHYHVPLLVSPWSYSTYRGSLast
1 -84.100[R] COG2351 Transthyretin-like protein  ali  100  1MGRLTTHVLDTAAGTPGKDLAITLFKIVNNLRQPIKTVRTNHDGRCEAPLLEGEALQAGIYELDFAVGDYYRAAGVSLPDPAFLDVVTLRFGVADAGAHYHVPLLVSPWSYSTYRGS 117
2 -51.800[I] KOG3006 Transthyretin and related proteins  ali follow..  32  203RPPITTHVLDVSRGAPAAGVEVHLEVWSGGVWSSVGTSATDRDGRSGPLMDLVDALNPGTYRISFDTAKYSPG--------CFFPYVSIVFQVTESQEHFHVPLLLAPFSFSTYRGS 324
3 -9.170[P] COG5266 ABC-type Co2+ transport system, periplasmic component  ali follow..  15  173.ERFKVRVL--FRGEPLPNATVTATFDGFDTSDRSKSDSTDDKGEVDIIPL-----RQGFWKAN---VEHKTDFPDQSVCQKQANYSTLTFQIGHSH---H................ 268
4 -8.030[S] COG4104 Uncharacterized conserved protein  ali follow..  13  117.......LIDHETGKPVAGRRVRVWSSGGW----NAFDTTDADGMTSWIERPTAE.............................................................. 160
5 -7.080[S] COG5321 Uncharacterized protein conserved in bacteria  ali follow..  11  5IPNQTHPLSDGRQSENALLVRRGVQRLFLAMGLATLPELSLASGRRADLIAVSRKGEIWIVEIKSSIEDWKADHKWPEYRAYC----RLFFATHPAVPREIFPILSDGYGAEILREA 123
6 -6.890[Q] COG3485 Protocatechuate 3,4-dioxygenase beta subunit  ali follow..  12  65...IKGRVIDG-MGAPLRDALVEIWQADAGLYNSPNESRGKADPHFRGWGRCPSNMETGEFIFELQTRMYFSDEEAANAEDPVLARIEPTLIGQREGDVYHFDIHLQGEKETVF... 211
7 -6.780[R] COG2373 Large extracellular alpha-helical protein  ali follow..  14  301.NRLDIFTQSLENGAAQQGIEVSLLNEKG---QTLTQATSDAQGHVAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFGPRDLYRPGETVILNGLL........... 409
8 -6.660[S] KOG3306 Predicted membrane protein  ali follow..  14  39.YTITGRVKIPPHIAKFSNVKVILNGGQ-------KITFLRPDGYFT------HEVPAGTHLIEVSAMGY-------------FSPVRVDVSARHRGK---VQATLTETRRSLT... 129
9 -6.620[M] COG4932 Predicted outer membrane protein  ali follow..  20  38MITLKIIKEDKDTKEKINGSSFEIK---NKKTGETKEVSITEDGTIV------NSLSEGEYIV----------KEKKAAPGFTLDEQTYNVTLADKDE................... 117
10 -6.160[S] COG4014 Uncharacterized protein conserved in archaea  ali follow..  14  1MQGLNASVLEAPRGESADAEEITAVGRNKKPILVGNAVKYVNSDTVSRVSEIKKDEEGNVWVLLESTDLWYREETLEYTDL.................................... 82
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.