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Query: [S] COG2469 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSDGERVLKIPVEYFEDGWKKGEAVITKDAISFAGKTIRFKEIQDLERLKHEGRDAIRIKKDADYFIDFGSRQAQIFRYLAFNLKSDRFAVYFLSPATRGGVVVSDSKWEKGYLSITDEALWFLSSSKQIRISIQNLGSVEKDIRTVGKKQRVVLVVTHVENGEVITSFVLCPETTMDMLQEYIQNFIEKSKPKEKLSEVEEQILTMVYTGVDSVSVESILGVTTEELNKMYDRLVNLGLARVVKIRKEIELTPRGVALVSEIMKKAARLast
1 -106.000[S] COG2469 Uncharacterized conserved protein  ali  100  1MSDGERVLKIPVEYFEDGWKKGEAVITKDAISFAGKTIRFKEIQDLERLKHEGRDAIRIKKDADYFIDFGSRQAQIFRYLAFNLKSDRFAVYFLSPATRGGVVVSDSKWEKGYLSITDEALWFLSSSKQIRISIQNLGSVEKDIRTVGKKQRVVLVVTHVENGEVITSFVLCPETTMDMLQEYIQNFIEKSKPKEKLSEVEEQILTMVYTGVDSVSVESILGVTTEELNKMYDRLVNLGLARVVKIRKEIELTPRGVALVSEIMKKAAR 269
2 -21.800[K] COG1846 Transcriptional regulators  ali follow..  19  25.....................................................................................................................................................................................RRLESTPRTFGRAGALTPSEIHTIDAIDEGLLMKELAERLGVTKGAVSQLVDRLEAKALVRRTAHPKVVVLTDKGREAYRAHADMHAA 119
3 -21.100[K] COG3355 Predicted transcriptional regulator  ali follow..  12  2.............................................................................................................................................................................AEKVRFPDGREVDIHDFIAFMYGLSKSDVEVLHILLQKMTTDDLSQKLNVTKASISKALNNLLDKGLIQREKEERKGRPNYIYWVEKERLYRKLEA 104
4 -18.800[KH] COG1339 Transcriptional regulator of a riboflavin/FAD biosynthetic operon  ali follow..  17  1....................................................................................................................................................................................................MKMKTLFLLIKLAKTVTMRELSRELDVSPQTVLRWLEELKEQGYIHKRESRKGVELTEKGINLLEKLYEEIST 83
5 -17.600[S] COG3373 Uncharacterized protein conserved in archaea  ali follow..  13  8.............................................................................................................................................................................................NILRSLNRSELRRKVLFYLLSRSYLSEISRAVKSDPSNVKGCLESLIGLGLVIVEQSKNGFKINPEIVEEVRNMKNMFSD 104
6 -17.300[K] COG5631 Predicted transcription regulator, contains HTH domain (MarR family)  ali follow..  12  46................................................................................................................................................................GGSPAMSEVEYGLILASHAFSRWMVRCM-AAAGLPGLSPIEILILHSIRHRKKLADICLALDIDTHIATYAIRKLEKAGLLTTAAKEKTVKITAKGAEACAHYAQIRER 159
7 -14.300[K] COG3432 Predicted transcriptional regulator  ali follow..  22  42..........................................................................................................................................................................................................DILRNCEPKCGITRVIYGAGINYVVAQKYLDQLVKVGALNIKTENDRYEITEKGKLLRTHIEE.... 106
8 -14.100[K] COG5625 Predicted transcription regulator containing HTH domain  ali follow..  15  8.........................................................................................................................................................................................KKLEDLLKAIGLKKNEIRIYRLLVEGMRIREIQRELGISERSVRTHVLNLYRRGLLKRELVQSG.................... 74
9 -12.600[K] COG4742 Predicted transcriptional regulator  ali follow..  16  12.....................................................................................................................................................................................................SQKRRDLLLLLGEERTMEDIKVLLDVSPTAILPQIKRLTDSNLVIQ--KNGSYELTDMGEQVFKKARA.... 78
10 -12.400[S] COG4344 Uncharacterized protein conserved in archaea  ali follow..  15  2.........................................................................................................................................................................................SEYEKEIDELINDYDMLRVLKHFTIAHVDKNITRYTEIPQMRVREYLKRLKDLGLLDYYKHHTYYQINKKAEAVLKEITPKLY. 105
11 -12.100[K] COG4738 Predicted transcriptional regulator  ali follow..  11  22........................................................................................................................................................................................EYEMVELLRRLNINRPVALTLACLSKEISSQRIEMVSGLRQPEVSIAMRYLRENEWVDKGRPVKLYKLTVQMETIIDTIEENVIA 117
12 -11.900[S] COG2512 Uncharacterized membrane-associated protein/domain  ali follow..  17  245...................................................................................................................................................................................................PLSPELCEVLDIIRGHITQKDLRSKLDYSEVKVSLMLSELEKRGLIRKLRRENILVLVDEEH............ 311
13 -11.600[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  8  7...........................................................................................................................................................................................FREIINDMDTLKRHISVINVLLREIGIIKLSQETGIPEHKIRYSLRILEQENIISPSR--EGAILTPDFIEHKEQIIADAEK 88
14 -11.600[K] COG1497 Predicted transcriptional regulator  ali follow..  23  9.....................................................................................................................................................................................................ELTRFQILSEIAMRVRQKDIADKLGVTVQAVSENIKSLIAEGLVESGSGRSHYKITRRGAEKIKEAAMDLRR 83
15 -11.400[K] COG1321 Mn-dependent transcriptional regulator  ali follow..  18  5....................................................................................................................................................................................................HTDRIEEYLETILY-AKTKQIAEELNVSSPSVTEMIKKLHSMGFVEYKPY-QGVELTEKGAEEAVRIKRK... 80
16 -10.600[K] COG4190 Predicted transcriptional regulator  ali follow..  10  67....................................................................................................................................................................................................LTPRVLELIEAIRQEASINETARVVDRDVKNVHEELSRLAHLGIIFFEEDGQRKRPVVWFDELVINL...... 135
17 -10.400[K] COG1510 Predicted transcriptional regulators  ali follow..  9  6.............................................................................................................................................................................LDIIEHAEEHLIEKIAENMHTFGMPSTVGRVLGIIYKPMTLSELSEATGMSKTRMSQVVREMIDANIAEKVFEKGV.................... 84
18 -10.200[K] COG1695 Predicted transcriptional regulators  ali follow..  16  1....................................................................................................................................................................................................MDRYAIKALVLLSKKPRTKEISTGVQVSHGTLMPMIRKLLQERYIETRGREKVYHLTERGSRFVESLGKIEED 80
19 -9.700[K] COG1378 Predicted transcriptional regulators  ali follow..  10  23........................................................................................................................................................................................MDEIIEVLKRLGFRDYEARVYATLATEATASEIHRVSGVPRNKVYEVLRSLEDRGMIETIKSSPAVFRAIDPESVLEEYKEQLVS 109
20 -9.600[S] COG4754 Uncharacterized conserved protein  ali follow..  16  19..........................................................................................................................................................................................................YVMNNIFDGTDLYQLEKEMEVDIDDLMPIVYTASRLGFVSAES--GDIIVTEEGKEYIRASIKRRKE 84
21 -9.270[S] COG1356 Uncharacterized protein conserved in archaea  ali follow..  19  5....................................................................................................................................................................................................LTEQQIKVLVLRAKGLKQSEIARILKTTRANVSILEKRALEK............................... 46
22 -9.210[L] COG3415 Transposase and inactivated derivatives  ali follow..  13  1..........................................................................................................................................................................MGRKRVYEVVKHLPAEELDKRIKKLEKDTQRLYFIRYLYRGMSVEEAAELVGITKATGYTWLKRWNTRGLIPEFGGGRPSKLTKDQKEELKEMLKERDS 105
23 -9.030[K] COG2345 Predicted transcriptional regulator  ali follow..  21  15.....................................................................................................................................................................................................GDTRRKILLILLEPVIASDIAEQLQLSTVGVRRHLDNLVEENLAEAARPAKTYRLTDKGRSIFGHEYDSLA. 100
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 4 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.