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Query: [K] COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDVSDLIKKGESETIEFKRELNDSVYKTLSAFANTDGGILLLGVSNDGKVFGFSGDLDSLARSIRHNLRINPPIKVEEIGEKKVVIIDVSKSPVPISFKGRYYKRVGAQTVEMGWEDLQRFFLQKSGVTWDSLPSSAALEDLDEETIRKFVHMARNRLPYINENEDVESILDKLGLLEDGKITNAALLLFGKEPQRYYIQAKVRIGRFKDPITIIDDKEIGGNLFTQVEEVMKVIMSHIGVRYEFEGELRRKEIWDYPLDALREAIINALIHRDYTDPSNVQIKIFRLast
1 -114.000[K] COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen  ali  100  1MDVSDLIKKGESETIEFKRELNDSVYKTLSAFANTDGGILLLGVSNDGKVFGFSGDLDSLARSIRHNLRINPPIKVEEIGEKKVVIIDVSKSPVPISFKGRYYKRVGAQTVEMGWEDLQRFFLQKSGVTWDSLPSSAALEDLDEETIRKFVHMARNRLPYINENEDVESILDKLGLLEDGKITNAALLLFGKEPQRYYIQAKVRIGRFKDPITIIDDKEIGGNLFTQVEEVMKVIMSHIGVRYEFEGELRRKEIWDYPLDALREAIINALIHRDYTDPSNVQIKIFR 287
2 -6.130[S] KOG4703 Uncharacterized conserved protein  ali follow..  10  4....................................GGLLVLGVTTLELANDFQNALRRLMFAVEKSINRKRLWNFTEEEVSERVTLHICASTKKIFCRTYDIHDPKSSARPADSYTLEKNTKNGLTRWAKEIENGVYLINGQVKDEDCDLLEGQKKSSRGNTQATSHSFDVRVLTQLLLNSDHRSTATVQICSGSVNLKGAVKCRAYIHSSK----QAVKRDILNTVADRCEMLFEDLLLNEIPEKKDSEKEFHVLPYRVFVPLPGSTVMLCDYKFDDE....... 284
3 -6.080[R] COG5258 GTPase  ali follow..  15  2.....FPPESEDGNVEYKLTLGPQDVDRMAGLAEGGGEAVYIGVSNDGRPLGLVKALETLREMARRVGASLYILRVSEGIRGKVAEVLLRAVSREEPPPTVTVVALGN--------------VDAGKSTLVGVLTTGRLDDGKGLARSYASRYKHEVLTGRTSAVSLR-----LGFSGDKVVNHGLIDPLDEAEVYKRSDKLVLLVDVGGHERYL-RTALRGLFSSQPDYVMLVVAANSGVQKMTKEHLGIAVAIGIPVFVV-------VTRIDITPSEVFQKTV.. 266
4 -5.570[S] COG5568 Uncharacterized small protein  ali follow..  11  11FTDNEFAHLGEGEIAYVRKIRSDDLARSFPSLPPIAPGLELWALGASGEPIVLSDVRATALQGAHDH............................................................................................................................................................................................................................ 78
5 -5.340[V] COG2367 Beta-lactamase class A  ali follow..  1..............MKLNRKMTMTVAEQLNAICDVQPFVTRFMVRNTGEEIGRGEN-EETPSGSTRKTSIMMAVLKAASEGRIDLDQPVTYEKRLAEEVASGMFRYMTPGIVISLRDAIAGMMVLS----DNVCTKMVLERLTLEEVDGYCKSLGMANTHHRFLIPPLALAADHPLKTVTTTSAADQILDAQSSPEAQAKLGCSPQLCEWAMQTLKNQILRYGIRSRLPFEAMVASK.................................................. 226
6 -5.260[S] COG0718 Uncharacterized protein conserved in bacteria  ali follow..  11  6.GIGNLMKQAQQMQEKMQQM--QEEVAKLEVTGESGAGLVKVTINGAHNCRRVEDDKEMLEDLIAAALN.......................................................................................................................................................................................................................... 79
7 -5.020[C] KOG4634 Mitochondrial F1F0-ATP synthase, subunit Cf6 (coupling factor 6)  ali follow..  11  39...............................................................................................................................................................................................................FLDKVREYKQKSAGGKLVDSNPDIERELKTELDRVAKQFGSDGKTDMLKFPEFQFPDVKVDPITQAP............. 105
8 -4.780[R] COG3193 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol  ali follow..  10  1MTKLTLEVANSIINRACSTASGKGLKPLSVAVLDAGGHLVAFQKQDGASMLRFEIAFGKAYGALAVGFGSRWLDKASADRPHFVAGLTSISGGKIVPVPGGVLVRDQAGRL------LGAVGITGDTSDNDEAVAVEAIEIGGLNA............................................................................................................................................. 140
9 -4.730[K] COG1958 Small nuclear ribonucleoprotein (snRNP) homolog  ali follow..  12  1....................MQAKVENPLKSLRTAINRIVLVKLKDGSEYIGMNLVLRDCTEIREGTSEPVAKYGRVLIRGSNILFISVDYE................................................................................................................................................................................................... 80
10 -4.720[S] COG5428 Uncharacterized conserved small protein  ali follow..  13  1MNFE---PEADAAYLTLTQSGVLPEQQISAITTEGMEGEIEIDVDENGKVIGIE......................................................................................................................................................................................................................................... 53

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I. and Godzik A Connecting the Protein Structure Universe by Using Sparse Recurring Fragments. Structure (Camb.) (2005) Aug;13(8):1213-24