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Query: [MP] COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQSWRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTDSKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAATFTDCATGKRFMVANNAELERGYLAARGHSEKPVLLSVEGHFTLEANPDTGAPTKVLAPDTAGKFYPNQDCSSLGQLast
1 -97.300[MP] COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance  ali  100  1MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQSWRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTDSKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAATFTDCATGKRFMVANNAELERGYLAARGHSEKPVLLSVEGHFTLEANPDTGAPTKVLAPDTAGKFYPNQDCSSLGQ 236
2 -12.500[S] COG4939 Major membrane immunogen, membrane-anchored lipoprotein  ali follow..  13  1MLKKVAMITVVMASSLLLVGCGSSDDSSKDKKSTDTKQTE-DGTYKLEEKNFDDKGGFMSIEVKDGKITKANYDYKNKDGKLKSEDADYEKAMKDKVGTGPQEYLKQL-SLVKGQSASSVEVSGATHSSD.......................................................................................................... 147
3 -12.300[S] COG3126 Uncharacterized protein conserved in bacteria  ali follow..  10  1MPKALWQIVGGAALAVSLTGCAHQSAEAPVAAPISTATVAASVTVHGTVNIRE------RVALPPDAVVTVTLSDISLADAPSRVIAQKAVRTEGKQA.......................................................................................................................................... 99
4 -12.200[R] COG5633 Predicted periplasmic lipoprotein  ali follow..  11  1.MRKGCFG-LVSLALLLLVGCRSHPEIPVNDEQSLVMESSLLAA------------AEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAHSAVTLYGSANFLGAHK........................................................................................................... 118
5 -11.000[S] COG4808 Uncharacterized protein conserved in bacteria  ali follow..  18  8.FNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAITYVYKGD---KNIAGVEEKLTYTDT.......................................................................................................................................................................... 104
6 -10.900[N] COG5567 Predicted small periplasmic lipoprotein  ali follow..  20  1.MKNVFKTLAVLLTLFSLTGCGLKGPLYFPPADKNAPPPT.................................................................................................................................................................................................... 39
7 -10.500[R] COG5645 Predicted periplasmic lipoprotein  ali follow..  11  26MIRNVLLAFMICSGMALLGGCSSVMSHTGGK----------EGTYPGTMPFT----VMDTLLLPWDVFRKDSSVRSRVEKSEANAQAT.................................................................................................................................................... 123
8 -10.000[M] COG3065 Starvation-inducible outer membrane lipoprotein  ali follow..  10  7FRNHKWMYGWLGLGALLLSGCVTIPPAIQGTTATPLQDLN-PKLFIGQE-----GGTVVNVKNEPNRTLEIASVPLDSGARPILEPSQGRVIARGHLVTVVGPIVGVEAGKIGMTPYNFVVIKATGY............................................................................................................. 148
9 -9.700[S] COG4925 Uncharacterized conserved protein  ali follow..  11  10.IKWMLICLGVFLLAILATGCIEQNNIDQRAISNQSEMNSSEKTVSTEPEHGL-ALSEMSVKITSQGHIATFQLYDTVAAKE.......................................................................................................................................................... 89
10 -9.470[M] COG3017 Outer membrane lipoprotein involved in outer membrane biogenesis  ali follow..  7  2TLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQ--------------------QHQQEVRHLNQYQTRGA-FAYISDDQKVYARFFWQQTGQDRYRLL-GSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKPIPLNSLRQWILGLPGDATDYKLDDQYRLSEVNYRQDGKNWKVVYGGYDSKTQPAMPANME--------LSDGSQRIKLKMDN............... 203
11 -9.270[S] COG5429 Uncharacterized secreted protein  ali follow..  10  1MSRRSLWLAAFALAFSAVAGAGGETERIQAEKPSPDKPLGVVELFTSQ--CSSCPPADAFFELATKDDIVALSYHVD............................................................................................................................................................... 80
12 -9.260[S] COG4259 Uncharacterized protein conserved in bacteria  ali follow..  12  1MMNKTLSRLSLCAAVLALTACGGNGQKSLYYKNDDTSLGKQTEKMEKYFVEAG-PGAHAHLLLSRSGDKEGAFRQFEEEKRLFPESG..................................................................................................................................................... 108
13 -9.190[M] COG3040 Bacterial lipocalin  ali follow..  14  1.MRL-LPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTW-ARLD-RGLEQVTATYSLRDDGGINVINKGYNPDREMWQKTEGKAYFTGSPNIALDREYRHALVCGPDRDYLWILSRTPTLSEEIKQQMLAVATR................................................................................................ 161
14 -9.070[R] COG3042 Putative hemolysin  ali follow..  17  1.MKIIS---FVLPCLLVLAGCSTPSQPEAPKPPQANPASVYCQQKGGTLIPVQTAQGVSNNCKLPGGE........................................................................................................................................................................ 67
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.