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Query: [K] COG3711 Transcriptional antiterminator, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKINLWLEQEGYPKLERTSQGNFIVSSEIMTLFKRDVSEQQMLNGNNVIFSIETRRYYLMLMLFSKENAMSLNHFSIDLQVSKNTVIHDINHVKEQLEDHGLSLKYSRKHGYEIVGDEFEVRRFFIKLIDQRLNHDITKSEVLKALNLTFEDIAYQKDKIKQVEQFLKSRFIDKSLSSLPYVLCVIRRRIQSGHVMNPLNINYQYLRDTKEYQATEIMTQHEPDLPEAEKLYLTLHLLSTSVQWTDLQESDNISNLTMAIAQMIHHFEQITFINIEDKEKLSQQLLLHLTPAFYRIKYNLTDRDELINPLQGNYQSLFHMVKQSCQSLTEYFGKSLPDNEIAYLTMLFGGSLRRQDENFDGKIKAIIVCTQGTSVSQMMLYELRNLFPEIIFLDAISLRTFENYTLDYDIVFSPMFVLTHKKLFITKVALSENEQRKLRKEVMKYINKESADIDKEINKLMALIERTTTVNDITELRDGLEDFIANYNSISTINGSIVTQNKTLDLast
1 -132.000[K] COG3711 Transcriptional antiterminator  ali  100  1MNGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKINLWLEQEGYPKLERTSQGNFIVSSEIMTLFKRDVSEQQMLNGNNVIFSIETRRYYLMLMLFSKENAMSLNHFSIDLQVSKNTVIHDINHVKEQLEDHGLSLKYSRKHGYEIVGDEFEVRRFFIKLIDQRLNHDITKSEVLKALNLTFEDIAYQKDKIKQVEQFLKSRFIDKSLSSLPYVLCVIRRRIQSGHVMNPLNINYQYLRDTKEYQATEIMTQHEPDLPEAEKLYLTLHLLSTSVQWTDLQESDNISNLTMAIAQMIHHFEQITFINIEDKEKLSQQLLLHLTPAFYRIKYNLTDRDELINPLQGNYQSLFHMVKQSCQSLTEYFGKSLPDNEIAYLTMLFGGSLRRQDENFDGKIKAIIVCTQGTSVSQMMLYELRNLFPEIIFLDAISLRTFENYTLDYDIVFSPMFVLTHKKLFITKVALSENEQRKLRKEVMKYINKESADIDKEINKLMALIERTTTVNDITELRDGLEDFIANYNSISTINGSIVTQNKTLD 543
2 -23.400[K] COG3933 Transcriptional antiterminator  ali follow..  11  7........................................................................................................................................................................................IVNEEILNFAEGIEQRIEHQLGKKLNERFLLAFSLHLTSFIKRIESNKPLKYTNIENVVNDQPEAYELSRIEATFHIRVPNMEVMYLTLLISSLLKEQENARVNNTASSMVSVAKKLLGE-GLVEGIDMQSPKIVLDKLTERAKEMDMGRGLLLLVDMGSLTSFAPVISERTGIPVRSIDMVSTATVIEAELDSIYDSLKDFRGYGGYNSDSNQKPHAIVTICATGEGTAEKLQLFIENILDTITTDAIKVITRLEQLQEENDIAVGIQDPKIQIPFIPLERLFGIDGEEQLVSLVKQRNIIVKKGETGRIEIIEESLNEFLTYLNPKKTIEILSSFATV................... 387
3 -20.900[G] COG3414 Phosphotransferase system, galactitol-specific IIB component  ali follow..  10  2...............................................................................................................................................................................................................................................................................................................................................................................................................TVRILAVCGNGQGSSMIMKMKVDQFLTQSNIVNSCAVGEYKSELSGADIIIASTHIATVTGNKYVVGVRNMLSPADFGPKLLEVIKEH........................................................ 95
4 -14.100[S] COG3398 Uncharacterized protein conserved in archaea  ali follow..  14  109.NSNRARIYEYIKTRPGAYLSEIIEKAGIDRGAARYHIKILKA--------------HHKIEAYRESGKTRYFQNNSTYGEEEKKVVSALQNATNQRIISEIQNGKCNTNLALAREIGVSRATISWYVKNLKET------GLIDETRSGYSINPSYEPL................................................................................................................................................................................................................................................................................................................................................................................................ 250
5 -11.900[K] COG1654 Biotin operon repressor  ali follow..  17  4.TTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQT----LRDWGVDVFTVPGKGYSL................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 60
6 -11.200[S] COG3388 Uncharacterized protein conserved in archaea  ali follow..  9  16TLKRHISVINVLLREQPIGIIKLSQETGIPEHKIRYSLRILEQ-------NIISPSREGAILTPDFIE........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 77
7 -10.000[S] COG4519 Uncharacterized protein conserved in bacteria  ali follow..  12  8..ARRLYLALLVESLERPNVPKLIEKTGWPRRTIQDVIKAMPG.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 48
8 -9.390[K] COG2378 Predicted transcriptional regulator  ali follow..  13  24..SRLFEIIQILLARRPVTAQTIADMLEVTARSVYRDIAA----LQTMRVPIEGERGVGYILRSIEETEAIVLALAMVDRSGDAELRQAAKKVSDKIAASL-PLSKTLSANALHAWGSIAPAPAGIDLATVRRAVRDEELDLCYSDESG------VETQRRI............................................................................................................................................................................................................................................................................................................................................................................................. 186
9 -9.070[G] COG1440 Phosphotransferase system cellobiose-specific component IIB  ali follow..  10  2................................................................................................................................................................................................................................................................................................................................................................................................................KNILLICGSGASSG-FMAAAIRKAAKKRGEVKAASESQIDERINEIDYLLIGPHLDKDVLVSVIPQTYGTLNGEKALDLILNMEG.......................................................... 101
10 -8.380[K] COG3355 Predicted transcriptional regulator  ali follow..  6  25LSKSDVEVLHILLQNGKMTTDDLSQKLNVTKASISKALNNLLD.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 67
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 3 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Grynberg M, Erlandsen H, Godzik A. HEPN: a common domain in bacterial drug resistance and human neurodegenerative proteins. Trends Biochem Sci. 2003 May;28(5):224-6. Review.