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Query: [S] COG3743 Uncharacterized conserved protein, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPKEMASAINLFVHPVAGAAAMSALGIGFANHAFGVWLGALTGAAEASQRLMQPLIEDFEARVEQFEDANSSSIKARATAKTMIAEAQSFAQEVTDIAAKEAATTAPAVNAAPAAGEAADVLLPEDFRQPKAMDKPAKPSDLKAISGIGPKLEKVLNGLGIWTYAQIAAWSPQEIAWVDDYLSFNGRIGRDDWTAQAAVLAAKKLast
1 -69.100[S] COG3743 Uncharacterized conserved protein  ali  100  1MPKEMASAINLFVHPVAGAAAMSALGIGFANHAFGVWLGALTGAAEASQRLMQPLIEDFEARVEQFEDANSSSIKARATAKTMIAEAQSFAQEVTDIAAKEAATTAPAVNAAPAAGEAADVLLPEDFRQPKAMDKPAKPSDLKAISGIGPKLEKVLNGLGIWTYAQIAAWSPQEIAWVDDYLSFNGRIGRDDWTAQAAVLAAKK 204
2 -9.530[L] COG3359 Predicted exonuclease  ali follow..  19  3..........................................................................................................................................KNTYIHIPGVGKALEQKIWASGINSWDEFLEMEDRI.............................. 38
3 -9.150[J] KOG3311 Ribosomal protein S18  ali follow..  19  30.............................................................................................................................................LTSIKGIGRRLANIVKKADVDMNKRAGELSAAEIDNLMTIVANPRQFKIPDWLNRQKDYKDGK 94
4 -7.870[P] KOG3574 Acetyl-CoA transporter  ali follow..  14  2......................................................................SPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAE-LYVLQGI-PSIPLILQSKNV-SYTDQAFFSFVFWPFSLKLLWAPGR--RKSWLVPTQYIL... 151
5 -7.680[R] COG2251 Predicted nuclease (RecB family)  ali follow..  28  229.........................................................................................................................................ATDDLLLIAGMRISQRSKLLNVGITTIAELADHSGPVPD............................ 267
6 -7.600[M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis  ali follow..  17  329...........................................................................................................SMKVMENDKVVTQATQNDPRVTRVGN-RRTSLDELNVLTGVGPRYRQLIEGYGITGWAQINGWRGE----TDTLEKMEKRVEFDEW........... 441
7 -7.580[R] KOG2350 Zn-finger protein joined to JAZF1 (predicted suppressor)  ali follow..  13  795.PASKRKLSSKDVEQAADAPEVLTHSDNAVDVGIIDDECGGFGAVGVMNGVASPVANNSEMDTEAEVEAEPTATKAITIHCQQPVTTPVAAAATANERLPGVAPHRRGPRRADRREEELVASAPGYRCRPSMRGADAGAAAAAAAAPTHPHPHR.................................................. 947
8 -7.320[L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair  ali follow..  16  177............................................................................................................................................PLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKFG..................... 219
9 -7.260[R] KOG2295 C2H2 Zn-finger protein  ali follow..  10  382............ESSSSSDEEKLKEKYDVEDGLRAEQKTEAEKDRQEATKAKQGPQSPKLDEDEGNENTEPKGLDSKINTYEEIDNTLKSPEISSNPIKNTDNGDGSKVEEDGEKPSVGKDKVVETETIDLDKVKDGQPRALHRLRNLAPEIEAVCNRFS---YLRVAIADPLVER----------RWYRRGWI.......... 561
10 -7.180[J] KOG2963 RNA-binding protein required for 60S ribosomal subunit biogenesis  ali follow..  14  256.......................................................................SESEIEDDAIVRVVDNQDVKAKHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTE-LGPRLTLKLVKIGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKKK 393
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.