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Query: [S] COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .
# Score Template Links and tools%idFirst MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQNINIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRALast
1 -49.500[S] COG3978 Acetolactate synthase (isozyme II), small (regulatory) subunit  ali  100  1MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQNINIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA 87
2 -40.200[E] COG0440 Acetolactate synthase, small (regulatory) subunit  ali follow..  21  3PKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTLEQITKQLNKLINVIKIVEQDDEHSVSRELA 90
3 -30.800[E] KOG2663 Acetolactate synthase, small subunit  ali follow..  19  74VRRHTISVFVGDESGIINRIAGVFARRGYNIESLAVGLNEDKA--LFTIVVLGTDKLQQVVEQLNKLVNVIKVEDLSKEPHVERELM 159
4 -27.100[R] COG1707 ACT domain-containing protein  ali follow..  13  1MTSVALSIKTVERPGVLSEITGMIASRNINITYAHLY-VERDGHGAIYMELEDIDDRESLINELKSSSTVLDVKIHRSLEEIYGKRI 86
5 -18.800[R] COG4492 ACT domain-containing protein  ali follow..  20  75....TLILYVTDIVGMLARVLDVISKLELSVLTIHQSIPMEEATITLSLNAKSETSVEDVIGALRNLDYVSKVELISMS........ 151
6 -13.000[E] COG2716 Glycine cleavage system regulatory protein  ali follow..  10  116.ASVWVQVDVADSPHLIERFTALFDAHHMNIAELVSRTQPAENHIQITAHSPASADAANIEQAFKALCTELNAQGSINVVNYSQHD. 206
7 -12.900[E] COG2061 ACT-domain-containing protein, predicted allosteric regulator of homoserine dehydrogenase  ali follow..  8  23....SMDIELKDVPGQMLLALQPLSEFKANLITVLHHHQKRTPRKTVPVQLVKPESIEVIKAKLEE..................... 87
8 -12.300[R] COG4747 ACT domain-containing protein  ali follow..  17  7...KQISLFAENKPGRLASVANKLKSAGINIRAFTIAESGDFGI--IRMVVDRSDYAHSVLHEAGFTVSETSV.............. 74
9 -11.800[T] COG3830 ACT domain-containing protein  ali follow..  16  27YLPAVITVSGKDRPGVTAAFFRVLSANQVQVLDVEQSMFRGFLNLAAFVGIAPER-VETVTTGLTDTLKVHGQS............. 99
10 -11.200[R] COG2150 Predicted regulator of amino acid metabolism, contains ACT domain  ali follow..  12  99....ELTISKKAYESTVAMVLNGLAKRRIRVIEI-FGTNTYEGKAKVYIVIEGVLP-FDMIAELKKTNTIEKIVIRTSEKDKEKMIC 179
11 -10.600[TK] COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases  ali follow..  19  665.....VRVEAMERSGLLKDITTLLANEKVKVASMKSRSDYKRQIIDFDLEVNNVEALARVSKRIEQIKDVMLVKRLG.......... 738
12 -10.200[S] COG2921 Uncharacterized conserved protein  ali follow..  19  14..PFTYKVMGQALPELVDQVVEVVQRHAPGDYTPTVKPSSKGNYHSVSITATHIEQVETLYEELGKIDIVRMV.............. 86
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rodrigues AP, Grant BJ, Godzik A, Friedberg I. The 2006 automated function prediction meeting. BMC Bioinformatics. 2007 May 22;8 Suppl 4:S1-4.