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Query: [S] COG4223 Uncharacterized protein conserved in bacteria, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRHSKSRREPVTIDLEPGAVSRIVDEDAAKAAAQTDEAKAEEAADASQPEAPEEPVHADQTDLEPWEHADGVGQAGTEPSAEAKAVEPEMPYPGSDAPADRSAASDYNFEDASAKRSDGSKAKTQTRDEKMAPTPAAAKRGGLNGIAAGIIGGVIALAGAGGLQFAGLLGAPGSGAGVSLDGVNGEIASLKSEIAGLKETGGNNDAAAKVVGLSSGLEQVKADIAALKSAVEKGGAGDNAGLAALGDKVKQIETAVAALGKAGSAAPVDLGPLNEKLAGLDALVKSTGEAAKAQDSRLAALEQSVSQLSGKVEAAAGQPKIALAIAASALKSALERGAPFSAELDTLAAISPNAPELATLRPYAEKGVPTRTEIASQMDAAANAMVAAATPADQNAGFLQNLMSSAQSLVKVRPIGAVEGPGAPETVARMEVAVRQGDYAKALSEYNSLPEAVKAAGADFAGKLKARIEVETQVDALISGAMKALast
1 -73.600[S] COG4223 Uncharacterized protein conserved in bacteria  ali  100  1MRHSKSRREPVTIDLEPGAVSRIVDEDAAKAAAQTDEAKAEEAADASQPEAPEEPVHADQTDLEPWEHADGVGQAGTEPSAEAKAVEPEMPYPGSDAPADRSAASDYNFEDASAKRSDGSKAKTQTRDEKMAPTPAAAKRGGLNGIAAGIIGGVIALAGAGGLQFAGLLGAPGSGAGVSLDGVNGEIASLKSEIAGLKETGGNNDAAAKVVGLSSGLEQVKADIAALKSAVEKGGAGDNAGLAALGDKVKQIETAVAALGKAGSAAPVDLGPLNEKLAGLDALVKSTGEAAKAQDSRLAALEQSVSQLSGKVEAAAGQPKIALAIAASALKSALERGAPFSAELDTLAAISPNAPELATLRPYAEKGVPTRTEIASQMDAAANAMVAAATPADQNAGFLQNLMSSAQSLVKVRPIGAVEGPGAPETVARMEVAVRQGDYAKALSEYNSLPEAVKAAGADFAGKLKARIEVETQVDALISGAMKA 484
2 -46.300[M] KOG1854 Mitochondrial inner membrane protein (mitofilin)  ali follow..  13  395....................................................................................................................................................................................CQLSDQQVREELHISKALEEQRLADERIASEKLSIEMSRVGRQNEEIERALVESRSSWEGELENQLKRTASAHSEHLEQVIRTQRQLFEIEQNQKVEEAVLQERNLHSKQVGAALSRLEGIEEALGSRVALDN--ENRRAKQFWIACHNLIDTLKHGLPLNESLNLLKEVNPEDEFVNAIKQATTVGTYTEQDLKNRFEQLYKIGRKTASIDENGGTLGAYFWSYVKSLFLVDMPIDVNNTDNYEILSRAKQYVHNGDLDKAIRVVQLLKGQPAHLARDWIVDTRSYLESRLLAQLLVAHAAVS 721
3 -9.800[U] KOG4809 Rab6 GTPase-interacting protein involved in endosome-to-TGN transport  ali follow..  12  416................................................................................................................................................................................TEEREEEMKQMEVYRSHSKFMKNKIGQVKQE--LSRKDTELLALQTKLETLTNQFSDSKEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQ--------LRDKEKQMSS----KERVKSLQATTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLD-SSLASSGLKKDSRLKEIALEQKKEECLKMESQLKKAHEA-ALEARASPEMSDRIQHLEREITR. 718
4 -9.120[S] COG5412 Phage-related protein  ali follow..  13  1....................................................................................................................................................................................................MADYTLTAKLTADPSGFRAGFQKAQESLANLQSRVNQTGKRVQSIGKSISDLGSKLTRNITVPAVGAATALTSITLVKG---DRLVGIDSARAKLKGLGHDAEAIDSIMDSALASVKGTAFGLDEAATTAANAVAAGIPPGKELTRYLSLTADTAAIAGT-SELQMLSDRGLPVYQWLAEEANTTADAIFDMA---SKGEISTDMLLNAIEKNIG--AAKIMGEESFSAAIANIGADIARANFLDAGGKAGGFFSTVKPLLTEFRGFLAQVEEQAADWGVAFGQAFNN 303
5 -8.880[U] KOG1162 Predicted small molecule transporter  ali follow..  8  31.........................................................................KKIKTSRKPKPASHYPIGHHSDFGRSLFDPVRKLARTFSDKLFSNSEKPEILQVRRRRGSSETGDDVDEIYQTELVQLFSEEDEVKVFFARLDEELNKVNQFHKPKETEFLERGEILKKQLETLAEKQILSDRKKRNLSGSNSHRSFSSSVRNSDFSAGSPGELSEIQSETSRTDEIIEALERNGVSFINSATRSKTKGGKPKMSLRVDIPDAVAGAEGGIARSIATAMSVLWEELVNNPRSDFTNWKNIQSAEKKIRSAFVE---LYRGLGLLKT-------------YSSLNMIAFTKIMKKFDKVAGQNASSTYLK------------------VVKRSQFISSDKVVRLMDEVESIFANNDRKKAMKFLKPHQTKDSHMVT.......................... 386
6 -8.720[U] KOG0946 ER-Golgi vesicle-tethering protein p115  ali follow..  8  740.............................................................................................................................................................................EELKRNQELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSEQVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTEAFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELKNEIKALSEERTAIKEQLDSSNS-TIAILQTEKDKLELEITD----KKEQDDLLVLLADQDQ-------------KILSLKNKLKDLGHPV-----------------------------------EEEDELESGDQEDEDD-ESEDPGKDLDHI................................... 962
7 -8.120[U] COG4965 Flp pilus assembly protein TadB  ali follow..  9  32...............................................................................................................................................................................................................................................ETEKKAEGRLRRVSASETDRTKIKAARDRVNEMSKRRKSVQDSLKELEKKQQEKSANTAPSMKKRLLQVGSMVKRRCRKFLDEFPNSLDVMVRSIKSGLPLNDALRLIASDGQERTEFRRVVESQQVGLNVPEACARMIHSIVNFFAIVIAIQAQAGGNLSEALGNLSKVLRER-----------KMKAKVSALSMEAKASACI--IGALP.................................. 286
8 -7.680[S] COG5280 Phage-related minor tail protein  ali follow..  9  15..................................................................................................................................................................................DTTGVTNGLKDIGKQSNSVNSELRDVERLNNVELVAQKQQLLSKQVELTTKKLDGLKGAQAD-VDRQFKSGDIGEEQYRAFQREVVATEGRLDHYKQSLKDVESSSGEAGNATKGLGGKFDELGQSVEDVGEAVKGGVLMEAADHLSVVGD-GSAQEAFSDVDEGMDKITTTTGKAS--DEFKTQFDN-----SMAVDSFEDVGSALGTLSAQFDMSG---DTLEKNSKLALQYANIN---DTDVKTSIESAKSAIEADSLFDSAVKIKDLGLNFSQGTELLGQFSKAGVDGDAALSSLSKASII. 348
9 -7.170[M] COG3264 Small-conductance mechanosensitive channel  ali follow..  13  66............................................................................................................................................................................IKQYQEVIDNYPKLSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQ----EQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQEELAEKESQQLDAYLQALRNQLNSQRQLEAE-RALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVLNTLREQSQWLGSSNLLGEALRAQVARLQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILAQLRTQRELLNSLLQG 396
10 -7.000[UZ] KOG1961 Vacuolar sorting protein VPS52/suppressor of actin Sac2  ali follow..  8  3...........................................................................................................................................................................................EVPSPQMTEQLDNEEVREILKNTTDLRQYSRQIEKEFKEVENKSIEDYIAESQNIANLHNQINDCDDVLERMENMLMSFQSVLNNISTEITQLQRKSVSMSLQLTNRQSVKAQLSQFIEDMAVSEE------------MINIIMETPVTERDFSTQLNVLNH------KLSLVKELSFKESKSTSDVSDVLQKLRLKAM-------------AKIRSYLLEQIYKFRKPMTNYQIPQNAM------LKHKFFFEFILSNE--RHVAQEICSEYIDTMGKYSYFKSYSTRLTSLKFEE 262
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Reed JC, Doctor K, Rojas A, Zapata JM, Stehlik C, Fiorentino L, Damiano J, Roth W, Matsuzawa S, Newman R, Takayama S, Marusawa H, Xu F, Salvesen G, Godzik A.; RIKEN GER Group; GSL Members. Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res. 2003 Jun;13(6B):1376-88.