| | | | | | . 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . 90 . 100 . 110 . 120 . 130 . 140 . 150 . 160 . 170 . 180 . 190 . 200 . 210 . 220 . 230 . 240 . 250 . 260 . 270 . 280 . 290 . 300 . 310 . 320 . 330 . 340 . 350 . 360 . 370 . 380 . 390 . 400 . 410 . 420 . 430 . 440 . 450 . 460 . 470 . 480 . 490 . 500 . 510 . 520 . 530 . 540 . 550 . 560 . 570 . 580 . 590 |
# |
Score |
Template |
Links and tools | %id | First |
MAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDSDSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTANHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDIAHFRYAYASDNQRRGLKPPPRSIPLSMLPGDVEAMFQQAFTESGVATARPTAKAWVAALDLLRQQLKKCTVSAMHVYPGHLTDCPWCALDNQGVIYFIDLGEEVITTSGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYIILIEIALSALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKVYKAEIQQRREAFNRAKMDYDHLVSQIQQLGGLEGFIAKRAMLEKMKDEILGLPEEEKRALAALHDTARERQKQKFLEGFFIDAASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVIDWKASCERRFVFRPNEAVTPAERQAVMAKMAAKRHRLESALTVGATELQRFRLHAPARTMPLMEPLRQAAEKLAQAQADLSRC | Last |
1 | -158.000 | [R] COG4248 Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains |
ali |
100 | 1 | MAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDSDSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTANHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDIAHFRYAYASDNQRRGLKPPPRSIPLSMLPGDVEAMFQQAFTESGVATARPTAKAWVAALDLLRQQLKKCTVSAMHVYPGHLTDCPWCALDNQGVIYFIDLGEEVITTSGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYIILIEIALSALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKVYKAEIQQRREAFNRAKMDYDHLVSQIQQLGGLEGFIAKRAMLEKMKDEILGLPEEEKRALAALHDTARERQKQKFLEGFFIDAASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVIDWKASCERRFVFRPNEAVTPAERQAVMAKMAAKRHRLESALTVGATELQRFRLHAPARTMPLMEPLRQAAEKLAQAQADLSRC |
591 |
2 | -31.600 | [RTKL] COG0515 Serine/threonine protein kinase |
ali follow.. |
17 | 65 | MAELNHPNIVAIR---------GEEDGQQFLVMEYVDGADLKRYI-------QNHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKEGVVKVTDFGIAVAFAETSLTNSMLGSVHYLSPE-----QARGSKATIQSDIYAMGIMLFEMLT-GHIPYDGDSAVTIALQHFQKP------------------LPSIIEENHNVPQALENVVIRATAKKLS-DRYGSTFEMSRDLMTALSY....................................................................................................................................................................................................................................................................................................................................................... |
275 |
3 | -26.300 | [D] KOG0580 Serine/threonine protein kinase |
ali follow.. |
12 | 129 | QAHLHHPNILRLYNY--------YDRRRIYLILEYAPRGELYKELQKSCTFDE-------QRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG-WSVHAPSLRRKTMCGTLDYLPPEMIEGRMH-----NEKVDLWCIGVLCYELLV-GNPPFESA-----SHNETYRRIVKVDLKFP-----------------ASVPTGAQDLISKLLRH--NPSERLPLAQWVRA.............................................................................................................................................................................................................................................................................................................................................................. |
329 |
4 | -24.600 | [T] KOG0195 Integrin-linked kinase |
ali follow.. |
10 | 241 | LRIFSHPNILPIIG---------NSPPNLVTISQFMPRSSLFSLLHGATGVV-----VDTSQAVSFALDVARGMAFLHSLEIPTYHLNSHHVMIDDDLTAR-INMGDAKFSFQEK---GRIYQPAWMSPETLQRKQAD--RNWEACDMWSFAILIWELTT-REVPFAEWSPMECGMKIALEGLR------------------------PGTSTHMAKLISICMNE--DPGKRPKFDMVVPILEKMRR........................................................................................................................................................................................................................................................................................................................................................ |
448 |
5 | -24.500 | [T] KOG0616 cAMP-dependent protein kinase catalytic subunit (PKA) |
ali follow.. |
13 | 98 | ...LNEKRILQAIDFPVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRF-------YAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLC--GTPEYLAPEIILSKGY-----NKAVDWWALGVLIYEMAA-GYPPFFAD-----QPIQIYEKIVSGKVKFP-----------------SHFSNELKDLLKNLLQV--DLTKR-GSTDWIAIYQK........................................................................................................................................................................................................................................................................................................................................................... |
317 |
6 | -24.400 | [D] KOG0615 Serine/threonine protein kinase Chk2 and related proteins |
ali follow.. |
15 | 225 | MKKLSHPNIVA-------IYDCITVAKYSYMVIEYVGGGEFFSKLVDSKYNQMGLGESLGKYFAF---QLIDAVLYLHSVGICHRDIKPENILCSNKAELKLTDFGMAKNSVNRMKTHC--GTPSYCAPEIVANQ---GVEYTPKVDIWSLGCVLFITFS-GYPPFSE----EYTDLKMDEQVLTGRLFF--------------HEQWHRITDETQNMIQWMLT---EPLIRPSAVEWMKC.............................................................................................................................................................................................................................................................................................................................................................. |
437 |
7 | -24.300 | [T] KOG0581 Mitogen-activated protein kinase kinase (MAP2K) |
ali follow.. |
12 | 110 | VLAAPNTALQKQLLRELKINRSCTSPYIVKYAMEYCGAGSLDAIY---KRVRSQGGRTGERPLGKIAFGVLSGLSYLHDRKIIHRDIKPSNILLTSKGQVKLCDFG-VSGELVNSLAGTFTGTSYYMAPERISGGSY-----TISSDIWSLGLTLME-VALNRFPFPPEGSPPPMPIELLSYIINMPPPLLPQEPGIK------------WSKSFQHFLCVCLDK--DKTRRPGPQKMLT............................................................................................................................................................................................................................................................................................................................................................... |
339 |
8 | -24.000 | [T] KOG0033 Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily |
ali follow.. |
14 | 63 | CRKLQHPNI-------VRLHDSIQEESFHYLVFDLVTGGELFEDIVAREFYSE-------ADASHCIQQILESIAYCHSNGIVHRDLKPENLLLAKGAAVKLADFGLAIEVNDSEAWHGFAGTPGYLSPEVLKKDPY-----SKPVDIWACGVILY-ILLVGYPPFWDE-----DQHRLYAQIKAGAYDY-------------PSPEWDTVTPEAKSLIDSMLTV--NPKKRITADQWIC............................................................................................................................................................................................................................................................................................................................................................... |
270 |
9 | -23.900 | [T] KOG0604 MAP kinase-activated protein kinase 2 |
ali follow.. |
11 | 135 | .....................SYNGVDCLLVVMENMKGGELFNRIQERGQKA-----FTEREAAGIVNEICSAVAHLHRMSIAHRDLKPENLLYASNAALKLTDFGFAKKESEPQGLKTACFTPYYCAPEVLGTEKY-----DKSCDLWSIGVIMY-ILLCGYPPFYSQH-GQPMSPGMKAKIKSGQYTF-------------PSPEWDCVSEAAKDLIRKLLRT--EPTERITIEQWISHYRRVPDT....................................................................................................................................................................................................................................................................................................................................................... |
344 |
10 | -23.800 | [KIT] KOG2345 Serine/threonine protein kinase/TGF-beta stimulated factor |
ali follow.. |
14 | 100 | SSLFNHPNLLPLLDHAIISVKDGQEGA-AFLLFPVHLDGTLLDNF---TLMKAKKETFSTTDVLHIFRQLCDGLKHMHSLEYAHNDVKPGNVLLTRRKGAILMDFGSARPSRKQIRSRQEACSAPFRAPELWD---PSHADIDERTDIWSLGCTLYAIMY-GVSPFEYALGESGGSLQL--AIVNAQIKW------------PNTGPKASYPEALHQFVTWMLQP--QAAVRPRIDDIIIHVDKLIAKFTK.................................................................................................................................................................................................................................................................................................................................................... |
347 |
11 | -23.300 | [D] KOG0575 Polo-like serine/threonine protein kinase |
ali follow.. |
9 | 134 | HRILHHKHVVQFYHY--------EDKENIYILLEYCSRRSMAHILKARKVLTE-------PEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGAARLEPLEHRRRTICGTPNYLSPEVLNKQGH-----GCESDIWALGCVMYTMLL-GRPPFETTNL-----KETYRCIREARYTMP-----------------SSLLAPAKHLIASMLSK--NPEDRPSLDD-------IRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKNFFKKAAAALFGGKKDKARYIDTHNRVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEELQPPTTTVARSGTPAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLM-SGCSSELKNRMEYALNMLLQRCN............ |
685 |
12 | -23.000 | [T] KOG0983 Mitogen-activated protein kinase (MAPK) kinase MKK7/JNKK2 |
ali follow.. |
12 | 151 | MRRSGNKEENKRILMDLDVVLKSHDCPYI-IAMELMGTCAE-------KLKKRMQGPIPERILGKMTVAIVKALYYLEKHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVE-LATGQFPYKNCKTDFEVLTKVLQE------------------EPPLLPGHMGFSGDFQSFVKDCLTK--DHRKRPKYNKLLE............................................................................................................................................................................................................................................................................................................................................................... |
376 |
13 | -22.800 | [T] KOG0193 Serine/threonine protein kinase RAF |
ali follow.. |
15 | 397 | LRKTRHVNIL--------LFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETK------FQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRSQQVEQPTGSVLWMAPEVIRMQD--NNPFSFQSDVYSYGIVLYELMT-GELPYSHINNRDQIIFMVGR----------------GYASPDLSKLYKNCPKAMKRLVADCVKK--VKEERPLFPQILSSIELLQHSLPKINRSASE............................................................................................................................................................................................................................................................................................................................................. |
622 |
14 | -22.700 | [T] KOG0603 Ribosomal protein S6 kinase |
ali follow.. |
11 | 83 | ................VNLFYAFQTDTKLHIVMEYVRGGELFTHLCSRG-------HFDLEAARFVIAELVVAIDSLHQRKVIYRDLKLENILLDEEGHVKLTDFGLSKLPGELDRANSYCGTIEYMSPEVINRPEGG---YSDVVDWWSLGVISFELLT-GCSPFTVDG-AQNSSKDIAKRIMTKKVPF-----------------PKTMDVDARDFIGQLLEK--KLEKRLGYNGVDEIKNHKFMSSIDWDAAVKRTLKPVIVPRIGHDLDTQFFSAEFTSQPPLYSPAESPLNANTLFRGYSYVSPSVIFANDNVIGEELMAEDVNALLASSSFFAKYKL----DAGLLGKGAFSVVRRCERVVDGAQFAVKIVSQKFASQAQREARILEMVQGHIVQLHDVHSDPLHFYLVMEILTELLERIRKLERFTESERQLVSAVKYLHDKRIVHRDLKPENILFESIDSSARLR---LVDFGFYGLIAHNHLHSETPCFTLQYAAPEVLDWSLGVQVPFHARSRQESATEIMQRICRAEFSFTGDAWTNVSADAKNLITGLLTVDPKKRLSMQELTA............... |
662 |
15 | -22.500 | [T] KOG4236 Serine/threonine protein kinase PKC mu/PKD and related proteins |
ali follow.. |
14 | 627 | LQNLHHPGIVNLECM--------ETPERVFVVMEKLHGDMLEMILSSEKSRLPE------RITKFMVTQILVALRNLHFKNIVHCDLKPENVLLEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGY-----NRSLDMWSVGVIIY-VSLSGTFPFNED-------EDINDQIQNAAFMY-------------PPNPWREISGEAIDLINNLLQV--KMRKRYSVDKWLQ............................................................................................................................................................................................................................................................................................................................................................... |
833 |
16 | -22.500 | [T] KOG1027 Serine/threonine protein kinase and endoribonuclease ERN1/IRE1, sensor of the unfolded protein response pathway |
ali follow.. |
12 | 584 | ....THPHVIRYFC--------ESDSQFRYLALELCIAS------LNDYVEQKEVQQNVTIALRDIMKQATDGLAHLHASKIVHRDMKPQNVLITMASQAVISDFGLCKRVQPGKNASGLAGTDGWIAPEVLISAST-----SYPVDIFSLGCIFYYVLTSGTHPFGKS-------LHRQANIVNGEYTLN-------------KLADLDDWSLADDLISSMLNV--EPLHRLTADA---VLNH-----------------------PFFWTSEKRLAYFSDVSDRVEKEEDNSPVVRRIET-----------------------------------------------------------------DARIVVCGGWREKICDALKEDLRKFRTYKS---------------FSVRDLLRAMRNKKHHYRELPEDVRQSLGDIPDQFLHYFTSRFLHVYKATEYC------SGEAVFKRYYSDDVRARMYPIVEEEERVRKKIKEEMAN--ARAPKPVEQRTPLKLDKRNIKKKSNP...................................................... |
980 |
17 | -22.500 | [G] KOG0599 Phosphorylase kinase gamma subunit |
ali follow.. |
13 | 81 | ........LRQVMGHPIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSE-------KKTRTIMRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKLTNLCGTPGYLAPETLKCNMFEGSPYSQEVDIWACGVIMF-TLLVGCPPFWHRKQ-----MVMLRNIMEGKYSF-------------TSPEWADISEDPKDLIRKCLV---DPSQRITVKEFFNQ.............................................................................................................................................................................................................................................................................................................................................................. |
293 |
18 | -21.800 | [T] KOG0032 Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily |
ali follow.. |
15 | 160 | .......................EDEKAVNLVMELCAGGELFDRIIAKGHYTE-------RAAASVCRQIVNVVKICHFMGVLHRDLKPENFLLDEKALIKATDFGLSVFIEEGKVYRDIVGSAYYVAPEVLRRR------YGKEVDIWSAGIILY-ILLSGVPPFWAE-----TEKGIFDAILEGHIDF-------------ESQPWPSISSSAKDLVRRMLTA--DPKRRISAADWLREGGEASDK....................................................................................................................................................................................................................................................................................................................................................... |
358 |
19 | -21.600 | [T] KOG0984 Mitogen-activated protein kinase (MAPK) kinase MKK3/MKK6 |
ali follow.. |
11 | 100 | IRATVNSQEQKRLLMDLDINMRTVDCFYT-ICMELMDTSLDKFY----RKVLDKNMTIPEDILGEIAVSIVRALEHLHSKSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL-NQKGYNVKSDVWSLGITMIE-MAILRFPYESWGTPFQQLKQVVEE-------------------PSPQLPADRFSPEFVDFTAQCLRK--NPAERMSYLELME............................................................................................................................................................................................................................................................................................................................................................... |
326 |
20 | -21.600 | [T] KOG0578 p21-activated serine/threonine protein kinase |
ali follow.. |
12 | 298 | QMNLQQQPKKELIINEILVMRENKNPNIVNYVMEYLAGGSLTDVVTETCMDEGQ--------IAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY-----GPKVDIWSLGIMAIEMV--GEPPYLNENPLRA-----------------------ATNGTPELQNPERLSAVFRDFLNRCLEM--DVDRRGSAKELLQ............................................................................................................................................................................................................................................................................................................................................................... |
515 |
21 | -21.600 | [T] KOG0576 Mitogen-activated protein kinase kinase kinase kinase (MAP4K), germinal center kinase family |
ali follow.. |
15 | 47 | MVKMEPDDDVSTLQKEILILKTCRHANIVAYCMEFCGAGSLQDIYQVTGSLSE-------LQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGSAQIGATLARRLSFIGTPYWMAPEVAAVALKGG--YNELCDIWSLGITAIE-LAELQPPLFDVHPLRV---------------------TKSGYQPPRLKEKGKWSAAFHNFIKVTLTKS--PKKRPSATKMLS............................................................................................................................................................................................................................................................................................................................................................... |
270 |
22 | -21.300 | [T] KOG0986 G protein-coupled receptor kinase |
ali follow.. |
13 | 231 | ..ALNEKQILEKVNSQVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPG-----FEEERALFYAAEILCGLEDLHRENTVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRY-----GLSPDYWGLGCLIYEMIE-GQSPFRGRKE-KVKREEVDRRVLETEEVYS-----------------HKFSEEAKSICKMLLTK--DAKQRLGCQNFKRLEAGMLD........................................................................................................................................................................................................................................................................................................................................................ |
462 |
23 | -21.300 | [T] KOG3653 Transforming growth factor beta/activin receptor subfamily of serine/threonine kinases |
ali follow.. |
11 | 249 | VPLMEHDNIARFIV--GDERVTADGRMEYLLVMEYYPNGSLCKYLSLHT--------SDWVSSCRLAHSVTRGLAYLHTEAISHRDLNSRNVLVKNDGTCVISDFGLSMRLTGNRLVRSEVGTIRYMAPEVLEGAVNLRDCESKQVDMYALGLIYWEIFMR-QMAFQTEVGNHPTFEDMQVLVSR---------EKQRPKFPEAWKENSLAVRSLKETIEDCW--DQDAEARLTAQCAEERMAELMMIWER.................................................................................................................................................................................................................................................................................................................................................... |
510 |
24 | -21.100 | [T] KOG2052 Activin A type IB receptor, serine/threonine protein kinase |
ali follow.. |
11 | 310 | TILLRHENILGFIG---SDMTSRNSCTQLWLMTHYYPLGSLFDHLNRNA--------LSHNDMVWICLSIANGLVHLHTEAMAHRDLKSKNILVTSNGSCVIADFGLAVTHSHVTGNNPKVGTKRYMAPEVLDESDLECFEALRRTDIYAFGLVLWEVCRR-KVPFYDVVPMDPSFEDMRKVVCI-----------DNYRPSPNRWSSDSLMTGMSKLMKECWHQ--NPDVRLPALRIKKTIHKLASADEKIRLDFDE............................................................................................................................................................................................................................................................................................................................................. |
567 |
25 | -21.100 | [T] KOG0607 MAP kinase-interacting kinase and related serine/threonine protein kinases |
ali follow.. |
14 | 256 | ....DHPNI-------VQLLDWFEDETNFYLVMEKMRGGPLLQHILQRKYFTE-------EEARRVTKDISLALKFMHDRGIAHRDVKPENVLCNHVSPVKLCDLDPLSQVASEPDLASPVGSAEFMAPEVVDAYVGDSLKYDKKCDTWSLGVILYIMLA-GYAPFQGMCDDEDCQQDLFHRIQDGYYEF-------------PEEEWGMISEEAKDLVSNLLKR--DPVDRLVTVSFAN............................................................................................................................................................................................................................................................................................................................................................... |
491 |
26 | -20.700 | [R] KOG0589 Serine/threonine protein kinase |
ali follow.. |
13 | 55 | ISKMRHPFIVEYK----------EKACYVCIVIGYCEGGDMAQAI-----KKSNGVHFQEEKLCKWLVQLLMGLEYLHSNHILHRDVKCSNIFLTKEQDIRLGDFGLAKILTSDDLTSSVVGTPSYMCPELLADIPY-----GSKSDIWSLGCCIYEMAYL-KPAFKAF-----DMQALINKINKTIVS-------------------AKYSGPFRGLVKSMLRK--NPEVRPSASDLLR............................................................................................................................................................................................................................................................................................................................................................... |
254 |
27 | -20.600 | [R] KOG0605 NDR and related serine/threonine kinases |
ali follow.. |
11 | 229 | LTTTRSE-------WLVKLLYAFQDLQSLYLAMEFVPGGDFRTLLINTRCLKSGHARF-------YISEMFCAVNALHDLGYTHRDLKPENFLIDAKGHIKLTDFGLAA-EKEINYANSMVGSPDYMALEVLEGKKY-----DFTVDYWSLGCMLFESLV-GYTPFSGSSTNETYDNLRRWK--------------QTLRRPRQSDGRAAFSDRTWDLITRLIA---DPINRLRSFE.................................................................................................................................................................................................................................................................................................................................................................. |
469 |
28 | -20.600 | [D] KOG0601 Cyclin-dependent kinase WEE1 |
ali follow.. |
16 | 305 | ....FHENIVGYYSW--------FENEQLYIQLELCDHSLS-------ALPKKSSLKVSEREILVIMHQIAKALHFVHEKGIAHLDVKPDNIYIK-NGVCKLGDFGCATRLDKSL--PVEEGDARYMPQEILNE----DYEHLDKVDIFSLGVTVYELIKGSPLTESR---------NQSLNIKEGKLP-----------------LLPGHSLQLQQLLKTMMDR--DPKRRPSARELLDMFDRIRG........................................................................................................................................................................................................................................................................................................................................................ |
500 |
29 | -20.600 | [T] KOG4257 Focal adhesion tyrosine kinase FAK, contains FERM domain |
ali follow.. |
11 | 323 | MRQFDHPHIVKLIG-PVWIIME-TLGELRSFL-------------------QVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGK-KWMAPESINFRRF-----TSASDVWMFGVCMWEILMHGVKPFQGV-----KNNDVIGRIENGE----------RLPMPPN------CPPTLYSLMTKCWAY--DPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRSQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLIGNQHIYQPVGKPDPAAPPKKNLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPM-------VKEVGLALRTLLAT---ETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMT---------SLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRP.................. |
878 |
30 | -20.500 | [T] KOG4250 TANK binding protein kinase TBK1 |
ali follow.. |
9 | 72 | ....GASNIVQYFSNHTKMAPGSVTSETISFAMEYASSSLEAEMR-----RPKNHRGLSSNALIDLVVDCSMALSALREHNIAHRDIKHMNILLRSTHLFKLCDMGCSKSLSENSSMRTLVGTPNLLHPFLAHNWKTKSAYTSEQCDLWALGCTLYFCAT-GKFPFEHERNNKSLYHKAVVALTQ---------------------------PDAIAMVLVQKGR--DPGRRTDIFEFVSTMTCLLRSFFHEPSIEYYAKVADAMR----SISKCLGYPEGTDILLLSNTSTHYLDSKQKSVDGLPDDLYLVVPQTSHVDMRKILARNIEFHEFDDMTDRKLSEIRIKKCYEGLSMLTEIDEYLALFDRVSTILSTQFSLLVQELSQFERVQTASRFAVYVDMASVPLMLFDEANPETKMISDQCIQQAKRAREELERHAKVSMDIEAAKQLSKDAEDLRLEDMDLPGICEEIESYVFY---------DKQAILSTQKYSQELVELCLKRRNNIMEQIFNSPDRINKSKLNKAM--NLAASLSQLRSNYRKLQDMISECVDLLEKPFQEMKDTVNRYLQAQGCSRNTMQK. |
682 |
31 | -20.300 | [T] KOG0585 Ca2+/calmodulin-dependent protein kinase kinase beta and related serine/threonine protein kinases |
ali follow.. |
14 | 194 | LKKCVHPNVVRLR------VIDDPSSTKVYLVLEYMSGGEVPWTDCDS-------PVLSISEARQYFRDVVLGLEYLHYQGIIHRDIKPANLLLNSSNCVKISDFGVSYIEDNDVELAKTVGTPAFFAPELCWTDLDRPRPKIEAIDVWALGVTLFCLLF-GRCPFNASME-----YELFDKIVNERLNI---------------PSTPDIGEEGRDLLKRLLCK--DPEQRITLVEWTLD.............................................................................................................................................................................................................................................................................................................................................................. |
411 |
32 | -20.200 | [T] KOG1151 Tousled-like protein kinase |
ali follow.. |
8 | 495 | HKELDHPRIVKLYDY-------SLDTDSFCTVLEYCEGNDLDFYLKQHKLMSE-------KEARSIIMQIVNALKYLNEPPIIHYDLKPGNILLTACGEIKITDFGLSKIMDDDSLTSQGAGTYWYLPPECFVVGK-EPPKISNKVDVWSVGVIFYQCLY-GRKPFGHN---QSQQDILQENTILKATEVQF-------------PPKPVVTPEAKAFIRRCLA---RKRDRIDVQQYLL............................................................................................................................................................................................................................................................................................................................................................... |
719 |
33 | -20.100 | [T] KOG0614 cGMP-dependent protein kinase |
ali follow.. |
13 | 473 | ...FAERNIMMETSTDVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARF-------YVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGH-----DQAADYWALGIYICELML-GRPPFQAS-----DPMKTYTLILKGVDALEIPNRR--------------IGKTATALVKKLCRD--NPGER-MGFDWEGLRSR........................................................................................................................................................................................................................................................................................................................................................... |
697 |
34 | -20.100 | [T] KOG0690 Serine/threonine protein kinase |
ali follow.. |
12 | 238 | ..TLTENRVLQRCKHPTELKYSFQTNDRLCFVMEFAIGGDLYYHL--NREVQMNKEGFSEPRARFYGSEIVLALGYLHANSIVYRDLKLENLLLDKDGHIKIADFGLCKEESFGDKTSTFCGTPEYLAPEVLDDHDY-----GRCVDWWGVGVVMYEMMC-GRLPFYSK-----DHNKLFELIMAGDLRFP-----------------SKLSQEARTLLTGLLVK--DPTQRLGGGDWEATYRK........................................................................................................................................................................................................................................................................................................................................................... |
466 |
35 | -19.400 | [T] KOG0194 Protein tyrosine kinase |
ali follow.. |
12 | 221 | MTLLEHKNIVALYG-PIMLVIE-PGGDLRKYL--------------------QRTPNVPSKQIIKFAMEIASGMKHLSSKNVIHRDLAARNCLITKELNVKISDFGLSVNESETKMKSLKKAPIRWLSPETFSKGLF-----NEKTDVWSYGVLLTELMTCAHDPLWPK-----NLKQVQKWIKESE----------HPHKIE-----DGDPSELKEIVDACCAK--IPSVRINFREVKNRLAMLQQK....................................................................................................................................................................................................................................................................................................................................................... |
428 |
36 | -19.400 | [T] KOG1187 Serine/threonine protein kinase |
ali follow.. |
14 | 129 | LGVVEHPNLVKLIGY---CAEDDERGIQRLLVYEYVQNRSVQDHLSNRFIV----TPLPWSTRLKIAQDTARGLAYLHEFQIIFRDFKSSNILLDENWNAKLSDFGLARMSDGITHVSTVVGTIGYAAPEYIQTGHL-----TAKSDVWSYGIFLYELIT-------GRRPFDRNRPRNEQNILEWIRPHLSDIKKFKMIIDP-RLEGNYYLKSALKLAAVANR-MVKAKARPTMSQVSEMLERIVE........................................................................................................................................................................................................................................................................................................................................................ |
361 |
37 | -19.200 | [T] KOG0197 Tyrosine kinases |
ali follow.. |
16 | 288 | MKALQHERLVRLYA-PIYIVTE-ARGCLLDFL------------------KTDEGSRLSLPRLIDMSAQIAEGMAYIERMNSIHRDLRAANILVSEALCCKIADFGLARIIDSEYTAQEGAKFPKWTAPEAIHFGVF-----TIKADVWSFGVLLMEVVTYGRVPYPGM-----SNPEVIRNLERGY----------RMPRPDT------CPPELRGVIAECWRS--RPEERPTFEFLQSVLEDFYTA....................................................................................................................................................................................................................................................................................................................................................... |
496 |
38 | -19.100 | [T] KOG1345 Serine/threonine kinase |
ali follow.. |
13 | 75 | LHLGVHRHIVTTY----DVAFETA--GFYVFTQEYAPLGDLTSNVTDSGVGEVY--------SKRVAKQLASAIDYMHSKDIVHRDIKLDNVLIYRSDRIKLCDFG---SFPTGSTVERRNEWLPYSPPEVLEIKPEGSYKADPSHDVWQFGIVIFVCLT-GCLPWQKAASDDPRQGGLMMMPLRRTPRL------------------KLLTSNAQRMFKRFFA---ISNRPKSLADVTKFLDD........................................................................................................................................................................................................................................................................................................................................................... |
291 |
39 | -18.900 | [T] KOG0592 3-phosphoinositide-dependent protein kinase (PDK1) |
ali follow.. |
10 | 187 | ................FKLFFTFQDEASLYFLLEYAPHGDFLGLI-------KKYGSLNETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEYAKSKSFVGTAEYVSPELLNDNYT-----DSRCDIWAFGCILYQMLA-GKPPFKAA-----NEYLTFQKVMKIQYAFT-----------------AGFPQIVKDLVKKLLVR--DPNDRLTIKQFEDGIQPYKINAEAMKPLQKVSESDTTVKMA--AATSQEHSVISMTAATAAFNKDYTSQPKLGSKSSTSVRSASNNTDREVIQKKVSKNRASVSSPSISTTSRGKDNRSRSSDAFWSRYLQNMDERVLLMKEVALSTRNLEDSPVGLENVALDYKNPLDIEPPTDSAGKFYKKMFLITNLGRALVFVKRRSLSMWEEQEFELQFELELNDVEKIRFISDQVLEIDGSRTIFIGCKERAVLMKLWKLIHNGMTAKPKVVSPKSDHKMFDKFILQKRQNTKKKNQAPPVPQSNRLINGLPDRCILKTPEEGALHTKRPTSLQTRSSSNYSKLLARSTQMRKNMTRTDE........ |
765 |
40 | -18.900 | [R] KOG0597 Serine-threonine protein kinase FUSED |
ali follow.. |
11 | 55 | QARLKHPHVIEMI----ESFESKTD---LFVVTEFALM-DLHRYLSYNGAMGE-------EPARRVTGHLVSALYYLHSNRILHRDLKPQNVLLDKNMHAKLCDFGARNMTLGTHVLTSIKGTPLYMAPELLAEQPY-----DHHADMWSLGCIAYESMA-GQPPFCASSI-----LHLVKMIKHEDVKWP-----------------STLTSECRSFLQGLLEK--DPGLRISWTQFVEG.............................................................................................................................................................................................................................................................................................................................................................. |
256 |
41 | -18.800 | [T] KOG0696 Serine/threonine protein kinase |
ali follow.. |
15 | 401 | ...............PTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGR-------FKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENWDGVTTKTFCGTPDYIAPEIIAYQPY-----GKSVDWWAFGVLLYEMLA-GQAPFEGE-----DEDELFQSIMEHNVAYP-----------------KSMSKEAVAICKGLMTK--HPGKRLGCGDWEKLERK........................................................................................................................................................................................................................................................................................................................................................... |
611 |
42 | -18.800 | [T] KOG1024 Receptor-like protein tyrosine kinase RYK/derailed |
ali follow.. |
13 | 392 | LYEASHPNVLSVLG-----ISIEDYATPFVLYAATGSVRNLKSFLQDPSYAR----SVTTIQTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGE-KWLSLEALQKSHY-----NEGSDVWSFGVLMWEMCTLGKLPYAEI-----DPYEMEHYLKDGY----------RLAQPFN------CPDELFTIMAYCWAS--MPAERPSFSQLQICLSEFHTQITR.................................................................................................................................................................................................................................................................................................................................................... |
608 |
43 | -18.600 | [TDK] KOG0668 Casein kinase II, alpha subunit |
ali follow.. |
13 | 67 | VVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVLVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELL----VDYQMYDYSLDMWSLGCMLASMIFRREPFFHGQDNYDQ-LKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLR---DHQQRLTAKE.................................................................................................................................................................................................................................................................................................................................................................. |
318 |
44 | -18.600 | [T] KOG0583 Serine/threonine protein kinase |
ali follow.. |
14 | 86 | LKLLRHPHIIKLY----DVITTPTD---IVMVIEYAGG-ELFDYIVEKKRMTE-------DEGRRFFQQIICAIEYCHRHKIVHRDLKPENLLLDDNLNVKIADFGLSNIMTDGNFLKTSCGSPNYAAPEVINGKLYAG----PEVDVWSCGIVLYVMLV-GRLPFDDEFI-----PNLFKKVNSCVYVMP-----------------DFLSPGAQSLIRRMIV---DPMQRITIQEWFNV.............................................................................................................................................................................................................................................................................................................................................................. |
287 |
45 | -18.300 | [R] KOG0610 Putative serine/threonine protein kinase |
ali follow.. |
9 | 593 | LKMLDHP-------FLPTLYAHFTSDNLSCLVMECCPGGDLHVLRQKQPGRW-----FPEPAARFYVAEVLLALEYLHMLGVIYRDLKPENILVRDDGHIMVTDFDQLVAEPTDARSNSFVGTHEYLAPEIIKGEGH-----GAAVDWWTFGIFLYELLY-GKTPFKGA-----TNEETIANVVLQSLKFPDNPN---------------VSFQAKDLIRGLLVK--EPENRLGTEKGAAEIKR........................................................................................................................................................................................................................................................................................................................................................... |
874 |
46 | -18.300 | [T] KOG0694 Serine/threonine protein kinase |
ali follow.. |
17 | 467 | ...............PTQLYCCFQTKDRLFFVMEYVNGGDLMFQIQRSRKFDEPRSRF-------YAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGLNGVTTTTFCGTPDYIAPEILQELEY-----GPSVDWWALGVLMYEMMA-GQPPFEAD-----NEDDLFESILHDDVLYP-----------------VWLSKEAVSILKAFMTK--NPHKRLGCVASQNGEDAIKQH....................................................................................................................................................................................................................................................................................................................................................... |
665 |
47 | -18.300 | [T] KOG1094 Discoidin domain receptor DDR1 |
ali follow.. |
15 | 629 | MSRLKDPNIIHLLS-PLCMITE-ENGDLNQFLSRHEP----------PNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGKNYTIKIADFGMSRNLYSGDYYRIQGRAVRWMSWESILLGKF-----TTASDVWAFGVTLWETFFCQEQPYSQLS---------DEQVIENTGEFFRDQGRQTYLPQP-----AICPDSVYKLMLSCWRR--DTKNRPSFQEIHLLLLQQGDE....................................................................................................................................................................................................................................................................................................................................................... |
855 |
48 | -18.200 | [D] KOG0591 NIMA (never in mitosis)-related G2-specific serine/threonine protein kinase |
ali follow.. |
14 | 55 | LRNLKHPNIVQYC---------NRSAQVINLYMEYCGHGDLANLIQRYKEEKKRFTE---QEVLKFFTQLLLALYRCHKQSVLHRDIKPANIFLDENNSVKLGDFGLSKLDNTRVFTQSYVGTPYYMSPEIIRSSPY-----SAKSDVWALGCVIFEICML-THPFEGR-----SYLELQRNICQGNLS-------------------HHYSDDVFLLIRHCLEV--NSDLRPTTYQLLRSLSDIRSKLES.................................................................................................................................................................................................................................................................................................................................................... |
290 |
49 | -18.200 | [RT] KOG0598 Ribosomal protein S6 kinase and related proteins |
ali follow.. |
13 | 363 | ...............PVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKF-------YIAELVLALEHLHKHDIIYRDLKPENILLDADGHIALCDFGLSKANSANATTNTFCGTTEYLAPEVL----LEDKGYTKQVDFWSLGVLVFEMCC-GWSPFYAP-----DVQQMYRNIAFGKVRF----------------PKGVLSSEGRSFVRGLLNR--NPNHRLGAVNWDLLSKK........................................................................................................................................................................................................................................................................................................................................................... |
574 |
50 | -18.200 | [G] KOG0658 Glycogen synthase kinase-3 |
ali follow.. |
14 | 128 | MQMLDHPNAVAL----KHSFFSRTDNEELNLVLEFVP--ETVNRVARSYSRTNQ--LMPLIYVKLYTYQICRALAYIHNSGLCHRDIKPQNLLVNPHHQLKICDFGSAKVLVKGEPNVSYICSRYYRAPELI----FGASEYTTAIDIWSTGCVMAELLL-GQPLFPGESGVDQ-GTPTREEIKCMNPNYTEFKFPQIKPHPWHKVFQKRLPPEAVDLLCRFFQ---SPNLRCTALE.................................................................................................................................................................................................................................................................................................................................................................. |
360 |
51 | -18.100 | [T] KOG0574 STE20-like serine/threonine kinase MST |
ali follow.. |
12 | 91 | IKKVPVDTDLQEIIKEISIMQQCKSKYVVKYVMEYCGAGSISDIMRARRKPLSE------QEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGAGQLTDTMAKRNTVIGTPFWMAPEVIEEIGY-----DTKADIWSLGITAIE-MAEGRPPYSDIHPMRA-----------------------PTKPPPTFKKPEEWSSEFNDFIRSCLIK--KPEERKTALRLCE............................................................................................................................................................................................................................................................................................................................................................... |
310 |
52 | -17.900 | [T] KOG0665 Jun-N-terminal kinase (JNK) |
ali follow.. |
10 | 77 | MKCVNHKNIIGLVFTPQKSLEEFQD---VYIVMELMD--ANLCQVIQM--------ELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY-----KENVDLWSVGCIMGEMVC-HKILFPGRDYIDTPCPEFMKKLQPTVRTYVENRPKYAGYSPADSEHNKLKASQARDLLSKMLV---DASKRISVDE.................................................................................................................................................................................................................................................................................................................................................................. |
314 |
53 | -17.900 | [OUT] KOG0595 Serine/threonine-protein kinase involved in autophagy |
ali follow.. |
11 | 61 | LSTIDHPNIIRFY----EAI---ETGDRIFLVLEYCSGGDLAGYINRHGKVPE-------AVAKHFMRQLALGLQVLQEKHFIHRDLKPQNLLLSSKEVLKIGDFGFARSLTPESMAETFCGSPLYMAPEIIRNQKY-----DAKADLWSAGAILFQLVT-GKPPFDGNNHIQ-----FHNIVRDTELKFPEDTRN-------------EIHPDCVDLCRSLLRR--NPIERLTFREFLRE.............................................................................................................................................................................................................................................................................................................................................................. |
270 |
54 | -17.800 | [T] KOG4721 Serine/threonine protein kinase, contains leucine zipper domain |
ali follow.. |
13 | 208 | LRKLKHPNIIAFK----GVCTQAPC---YCIIMEYCAHGQLYEVLRAGR-------KITPRLLVDWSTGIASGMNYLHLHKIIHRDLKSPNVLVTHTDAVKISDFGTSKELSDKSTKMSFAGTVAWMAPEVIRNEPV-----SEKVDIWSFGVVLWELLT-GEIPYKD--------------VDSSAIIWGVGSNSLHLPVP------STCPDGFKILMKQTWQS--KPRNRPSFRQTLMHLDIASADVLATPQETYFK---------------------------------------------------------------------------------------------------------------------SQAEWREEVKKHFEKIKSEGTCIHRLDEELRRREELRHALDIREHYERKLERANNLYMELSAIMLQLEMREKELIKRE......................................................................................................................................... |
504 |
55 | -17.600 | [D] KOG0590 Checkpoint kinase and related serine/threonine protein kinases |
ali follow.. |
10 | 500 | ..KKPAPNILNVF----DILEDSSS---FIEVMEFCPAGDLYGMLVGKSKLKGRLHPLEADCFMK---QLLHGVKFMHDHGIAHCDLKPENILFYPHGLLKICDFGTSSVERRVHAQKGIIGSEPYVAPEEFVDGEYYD---PRLIDCWSCGVVYITMIL-GHYLWKV--------ASREKDMSYDEFYKEMQRKNQFRVFEELKHVNSELATNRKIALYRIFQ---EPRKRISVGKWMKSTN--------C................................................................................................................................................................................................................................................................................................................................................... |
728 |
56 | -17.400 | [T] KOG0201 Serine/threonine protein kinase |
ali follow.. |
14 | 60 | LSELKQSDVENIIKYHGSYLVGTN----LWIIMDYCHGGSVRTLM--------EAGPISEPCISLILRETLQALKFIHHAGIIHRDIKAANILVSMSGNVKLCDFGAAELNINRRKRITFIGTPYWMAPEVIR----DGQEYNVMADIWSLGITAYE-IATGSPPHAKEDPFRAVYLIAHTA-----------------------------PPRLNGNFSALLKE-DVPQRRLDSSELLK............................................................................................................................................................................................................................................................................................................................................................... |
260 |
57 | -17.400 | [T] KOG0582 Ste20-like serine/threonine protein kinase |
ali follow.. |
17 | 66 | MSLINHPNVLQAHC---SFTTGHQ----LWVVMPYMAGGSCLHII-----KSSYPDGFEEPVIATLLRETLKALVYLHAHGHIHRDVKAGNILLDSNGAVKLADFGSACMFDTGDRQRTFVGTPCWMAPEVMQQLH-----YDFKADVWSFGITALE-LAHGHAPFSKYPPMKVLLMTLQNA-----------------PPGLDYERDKRFSKAFKEMVGTCLVK--DPKKRPTSEKLLK............................................................................................................................................................................................................................................................................................................................................................... |
273 |
58 | -17.100 | [T] KOG0661 MAPK related serine/threonine protein kinase |
ali follow.. |
10 | 54 | LKKLNHANVIKL----KEVIRENDH---LYFIFEYMK--ENLYQLMKDRNK-----LFPESVIRNIMYQILQGLAFIHKHGFFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVL----LRSSVYSSPIDVWAVGSIMAELYML--RPFPGTSEVDEGTPKKSDWPEGYQLASSMNFRFPQCVPINLKTLIPNASNEAIQLMTEMLN---DPKKRPTASQ---ALKH........................................................................................................................................................................................................................................................................................................................................................... |
281 |
59 | -16.900 | [R] KOG0593 Predicted protein kinase KKIAMRE |
ali follow.. |
10 | 55 | LKQLKHPNLVNL----IEVFRRKRK---MHLVFEYCDHTLL-------NELERNPNGMDSDSIVGRLRSVADRSRLAPKNQCIHRDIKPENILITKQGIIKICDFGFAQILIPGDAYTDYVATRWYRAPELLVGDT----QYGSSVDIWAIGCVFAELLTG--QPWPGKSDVDGKLIPRHQSIFKSNGFFHGISIPEPEDMETLEEKFSDVHPVALNFMKGCLK---NPDDRLTCSQ.................................................................................................................................................................................................................................................................................................................................................................. |
285 |
60 | -16.900 | [R] KOG0586 Serine/threonine protein kinase |
ali follow.. |
15 | 107 | MKILNHPNIVKLF----EVI---ETEKTLYLIMEYASGGEVFDYLVAHGKMKEKEARSKFRQGCQMFTFIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDG----PEVDVWSLGVILY-TLVSGSLPFDGQNL-----KELRERVLRGKYRIPF-----------------YMSTDCENLLKRFLV---NPIKRGTLEQWINA.............................................................................................................................................................................................................................................................................................................................................................. |
332 |
61 | -16.900 | [UT] KOG0662 Cyclin-dependent kinase CDK5 |
ali follow.. |
9 | 37 | .LDEDDEGVPSSALREICLLKELKHKNIV--LIDVLHSDKKLTLVFEKKYFDSLNGEIDMAVCRSFMLQLLRGLAFCHSHNVLHRDLKPQNLLINKNGELKLADFGLARFGIPVKCYSAEVVTLWYRPPDVLFGAK----LYTTSIDMWSAGCILAELADAGRPLFPGSDVLDQLMKIFRVLGTPNEDSWPGVSHPSFPAITSWSQLVPRLNSKGRDLLQKLLI---RPNQRISAEA.................................................................................................................................................................................................................................................................................................................................................................. |
279 |
62 | -16.900 | [T] KOG0198 MEKK and related serine/threonine protein kinases |
ali follow.. |
14 | 339 | ..GIQAQECIQQLEGEIALLSQLQHQNIVRYRLELVTQGSVQKLYER---------QLSYTVVSLYTRQILAGLNYLHDKGFVHRDIKCANMLVDANGTVKLADFG-LAEASKFNDIMSCKGTLFWMAPEVINRKDSDG--NGSPADIWSLGCTVLEMCT-GQIPYS--------------DLKPIQAAFKIGRGTLPDVP-------DTLSLDARHFILTCLKV--NPEERPTAAELLH............................................................................................................................................................................................................................................................................................................................................................... |
553 |
63 | -16.800 | [R] KOG3087 Serine/threonine protein kinase |
ali follow.. |
11 | 104 | ..............................IWLEFLGEDLPGGHGFSNNFLWMHDQDPYSDLVATTLRKVGRQIGLLHWNDYCHGDLTSSNIVLVRDGTPHLIDFGLGSVSNLVED----KGVDLYVLERAILSTHS-----KHAEKYNAWIMEGFEEVYREQGAKGAKKLKEV--KRFEEVRLRGRK................................................................................................................................................................................................................................................................................................................................................................................................................... |
256 |
64 | -16.700 | [T] KOG0192 Tyrosine kinase specific for activated (GTP-bound) p21cdc42Hs |
ali follow.. |
11 | 698 | MLRLRHPNVVLFM----GAVTRPPN---FSILTEFLPRGSLYRLLHRPNH------QLDEKRRMRMALDVAKGMNYLHTSHVVHRDLKSPNLLVDKNWVVKVCDFGLSRMKHHTYLSSKSTGTPEWMAPEVLRNEPA-----NEKCDVYSFGVILWELAT-SRVPWKGLNPMQVVGAVGFQNRR------------------------DDIDLTVAQIIRECWQT.............................................................................................................................................................................................................................................................................................................................................................................. |
886 |
65 | -16.500 | [T] COG3642 Mn2+-dependent serine/threonine protein kinase |
ali follow.. |
13 | 55 | ..............................LKMQFIEGVPIKYLITP-----------------ELSEKVGELVGRLHSSGIVHGDLTTSNLLLAGER-LYLIDFGLAYFDKSLEARGVHVLFQTFESTH-----RGHETLVKAFEKGYGSTFIDSKDVL............................................................................................................................................................................................................................................................................................................................................................................................................................................... |
163 |
66 | -16.400 | [T] KOG1989 ARK protein kinase family |
ali follow.. |
13 | 101 | ....GHKNIVEFVD--SYTNCLGNGIWECMLLTEYHQK----NVLQLMNERISQNQYLTNDEILSIFTDLCEAVSFIHNRPIIHRDLKVENVLISSHKHYVLCDFGSATTQILSVEKYERNTTMCYRSPEMID---YSGLEIGLKSDIWALGVLLYRLCF-FCVPFEESPL----------AIQSVNYQFPSVPN---------------IPDEIKVLIYMLLDI--DVNRRPSIYQTSVLAFEANH........................................................................................................................................................................................................................................................................................................................................................ |
320 |
67 | -16.200 | [T] KOG0660 Mitogen-activated protein kinase |
ali follow.. |
8 | 92 | LLRFRHENVIGI----RDILRASTLEAMVYIVQDLME--TDLYKLLKSQ-------QLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINTTCDLKICDFGLARIADPTGFLTEYVATRWYRAPEIM----LNSKGYTKSIDIWSVGCILAEMLS-NRPIFPGKHYLDGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLFPKSDSKALDLLDRMLT---NPNKRITVEE.................................................................................................................................................................................................................................................................................................................................................................. |
323 |
68 | -16.100 | [R] KOG0611 Predicted serine/threonine protein kinase |
ali follow.. |
16 | 127 | MSALNHPNIIQIY----EVF---ENKDKIILVMEYSSGGELYDYVSRCGSLPE-------AEARRIFRQITSAVLYCHKHRVAHRDLKLENILLDQNNNAKIADFGLSNYFADKNLLTTFCGSPLYASPEIINGTPYKG----PEVDCWSLGILLY-TLVYGSMPFDGRDF-----NRMVRQIKRGAY----------------------EPSTASMLIRNMLR---NPERRATIFDWLNL.............................................................................................................................................................................................................................................................................................................................................................. |
328 |
69 | -15.900 | [TU] KOG1026 Nerve growth factor receptor TRKA and related tyrosine kinases |
ali follow.. |
16 | 592 | LTNLQHEHIVKFY--PLIMVFE-KHGDLNKFLRAHGPDAVLMAEGNPPT-------ELTQSQMLHIAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFDYYRVGGHTML--------RWMPPE-----SIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQL-----SNNEVIECITQGR----------VLQRPRT------CPQEVYELMLGCWQR--EPHMRKNIKGIHTLLQNLAKA....................................................................................................................................................................................................................................................................................................................................................... |
813 |
70 | -15.900 | [DKL] KOG0659 Cdk activating kinase (CAK)/RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH/TFIIK, kinase subunit CDK7 |
ali follow.. |
11 | 64 | LKELNHPHIVEL----IDAFPHDGS---LHLVFEYMQ--TDLEAVIRDRNI-----FLSPGDIKSYMLMTLKGLAYCHKKWVLHRDMKPNNLLIGENGLLKLADFGLARFGSPNRRFTHQVFATWYRAPELLFGSR----QYGAGVDVWAAGCIFAELLL--RRPLPGSTEIDQLGKTPVPSQWSDMIYLPDYMEFSYTPAPPLRTIFPMASDDALDLLAKMFI---DPRQRITIQQ.................................................................................................................................................................................................................................................................................................................................................................. |
286 |
71 | -15.600 | [D] KOG0588 Serine/threonine protein kinase |
ali follow.. |
16 | 69 | MKLIDHPHVLGLS----DVY---ENKKYLYLILEHVSGGELFDYLVKKGRLTP-------KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDG----RKADVWSCGVILYALLV-GALPFDDDNL-----RQLLEKVKRGVFHIP-----------------HFVPPDCQSLLRGMIE---NPDRRLTLAEWVTA.............................................................................................................................................................................................................................................................................................................................................................. |
271 |
72 | -15.300 | [T] KOG4717 Serine/threonine protein kinase |
ali follow.. |
12 | 67 | MKLVQHPNIVRLY----EVI---DTQTKLYLILELGDEGDMFDYIMKHEEGLNE------DLPKKYFAQIVHAISYCHKLHVVHRDLKPENVVFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA----PAVDIWSLGVILF-MLVCGQPPFQEAND-----SETLTMIMDCKYTVP-----------------SHVSKECKDLITRMLQ---DPKRRASLEEWLQG.............................................................................................................................................................................................................................................................................................................................................................. |
271 |
73 | -15.300 | [R] KOG0594 Protein kinase PCTAIRE and related kinases |
ali follow.. |
9 | 55 | LKELKHPNIVRL----LDVVHNERK---LYLVFEFLS--QDLKKYMDSTPGSE----LPLHLIKSYLFQLLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARFGVPLRTYTHEVVTLWYRAPEILLGSK----FYTTAVDIWSIGCIFAEMVT-RKALFPGDSEIDQLFRIFRMLGTPSEDTWPYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQ---DPSQRITAKT.................................................................................................................................................................................................................................................................................................................................................................. |
279 |
74 | -15.200 | [K] KOG0666 Cyclin C-dependent kinase CDK8 |
ali follow.. |
10 | 70 | LRELKHPNVISL----QKVFLSHADRKVW-LLFDYAEDLWHIIKFHRASKANKKPVQLPRGMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGRVKIADMGFARLFNSPADLDPVVVTFWYRAPELLLGAR----HYTKAIDIWAIGCIFAELLT--SEPFHCRQEDIKTSNPYHHDQLDRIFNVMGFPADKCSLIKYMEKHKVKPDSKAFHLLQKLLT---DPIKRITSEQ.................................................................................................................................................................................................................................................................................................................................................................. |
328 |
75 | -14.900 | [L] KOG1167 Serine/threonine protein kinase of the CDC7 subfamily involved in DNA synthesis, repair and recombination |
ali follow.. |
16 | 89 | LKHLIPTSHPIRIAAELQCLTV-RKNDHVVIAMPYLEHESFLDIL----------NSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRLKKYALVDFGLAQ-LSRRQQVAPRAGTPGFRAPEVL----TKCPNQTTAIDMWSAGVIFLSLLS-GRYPFYKASDDLTALAQIMT.......................................................................................................................................................................................................................................................................................................................................................................................................................... |
429 |