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Query: [L] COG4335 DNA alkylation repair enzyme, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MADLKEIYNEELISQLIHHVRSSYPDFNKNRFLDTLRLEDWPELTLKERMRRVTVSLYETLPKQYVEALTILRDTAPHFKGLSGILFPDYVEQYGLAHWEESIKALESFTQYSTSEFAVRPFLLLDQEKMIAQLLAWSEHKNEHVRRLASEGSRPRLPWGKSIPALKSDPSPVLPILEKLMQDESLYVRKSVANNLNDISKTHPHLLRKVADQWYGTHPHTDWIIKHAYRTLLKKGDKQALALFGYENADSIQLHDLTCQPKRIVIGESLEFSFYIHSDRDQKVRIEYAIDFVKARGQRHQKVFKITETNIRKNETKSYTRIQSFKDLTTRKHYKGIHTLSVIINGEVKDSLDFQVCLast
1 -115.000[L] COG4335 DNA alkylation repair enzyme  ali  100  1MADLKEIYNEELISQLIHHVRSSYPDFNKNRFLDTLRLEDWPELTLKERMRRVTVSLYETLPKQYVEALTILRDTAPHFKGLSGILFPDYVEQYGLAHWEESIKALESFTQYSTSEFAVRPFLLLDQEKMIAQLLAWSEHKNEHVRRLASEGSRPRLPWGKSIPALKSDPSPVLPILEKLMQDESLYVRKSVANNLNDISKTHPHLLRKVADQWYGTHPHTDWIIKHAYRTLLKKGDKQALALFGYENADSIQLHDLTCQPKRIVIGESLEFSFYIHSDRDQKVRIEYAIDFVKARGQRHQKVFKITETNIRKNETKSYTRIQSFKDLTTRKHYKGIHTLSVIINGEVKDSLDFQVC 357
2 -30.500[L] COG4912 Predicted DNA alkylation repair enzyme  ali follow..  13  1............MTTIQTLFRANRSV-ADSKPMEAYMKNQFPFLGIRERKKLVADFLRENGPDDLLRLVVELFAEEERELQYAAIDLLSRYGKKQASEAIEIYEQLWWDTVDGLAGTVVSNHFKLYPDLIPIYNEAWINGDNIWLARTAILFQLKYKE--------ETNAELLFANCEKWLGSKEFFIQKAIGWALRQYAKVDSEAVRVFVNS----HTLAPLSRREALKHIGEA.......................................................................................................................... 218
3 -8.600[R] COG5633 Predicted periplasmic lipoprotein  ali follow..  14  20...................................................................................................................................................................................................................................RSHPEIPVNDEQSLVMESSLLAAGISAEKPVLSTS----DIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAHSAVTLYGSANFLGAHK-------VRLYLYL............. 125
4 -6.990[U] KOG3317 Translocon-associated complex TRAP, beta subunit  ali follow..  14  53......................................................................................................................................................................................................................................................ETRARLLVSK-QILNKYLVEKSDLLVRYTIFNVGSGAAT-KVRLAFDVVGGQPTAVV------RIAPQTNFTHV-------LVVRPKAFGYFNFT................ 141
5 -6.750[N] COG5492 Bacterial surface proteins containing Ig-like domains  ali follow..  14  159.......................................................................................................................................................................................................................................................APEVVSVTGLTVEPTNATVGATTAVTFTVKPDNVTDKSLRIA--------TSDPTT-------------ATVTQAENIATVKGVK--AGTVKIIGMTDGNFTAIADITVQ 248
6 -6.520[S] COG5471 Uncharacterized conserved protein  ali follow..  18  1..................................................................................................................................................................................................................................................................MAKNYVEDGKTIEIVATTSLKSGDLVQVGDMFAVAVTDIAAGSAVFSIPKLTIAVGKKVYLKDNVVQTDATGSLPYVGV-TVPVKING........... 107
7 -6.240[J] KOG3291 Ribosomal protein S7  ali follow..  11  70........................................................................................................................................................................................ERLTNSMMMHGRNNGKK-----------------LMTVRIVKHAFEIIHLLTGENPLQVL----VNAIINSGPREDSTRIGRAGVRRQAVDVSPLRRVNQAIWLLCTGAREAAFRNIKTIELINAAKGSSNSYAIKKKDELERVAK........................... 201
8 -6.160[S] COG5330 Uncharacterized protein conserved in bacteria  ali follow..  11  1.........................................................................................................................MATTRAALTDADIRMLVKGATPDERALAAHKLCRSIDRSVLSE---EEREVAHDILRVMAADAAELVRRAMAVTLKNSLALPPDVANRLARDVESVSSFSPVFTDTDLAEIVKVGGPVRQMAVAKRPKLSSKITTLLVEQGTEDVVATVCANDNARFSEVS---LQKALDRFAKSEQVLQAVAYRSALPLAVTERLIDMVGEQLRDHILTSHALSPERTMELIL............ 222
9 -6.010[S] KOG1949 Uncharacterized conserved protein  ali follow..  16  167...............................................................................................................................QKQFEELYSLLEDPYPMVRSTGILGVCKITSKYWEMMPPTILIDLLKKVTGELAFDTSS-VRCSVFKCLPMILDNK-PLLEQLLPALRYSLHDNSEKVRVAVDMLLKIKAVRAAKFWKICPMEHI-LVRLETDSRPVS---SLIFNSFLPVNQPEEVWCERCVTLVQMNHAAARRFYQYAHEHTACTNIAKL...................................... 362
10 -5.900[S] COG3656 Predicted periplasmic protein  ali follow..  12  24...............................................................................................................................................................................................................................................AAAALGASRVVPGALAEAATSSKAWASGMQLDIQFSVATKASGRVKRPFAVWIEDESGKTVRTLTVWVQQRRLNPRWLE-DNGQLVSTVSSATRNPGTYAVA---KNALAPQGDYYV. 151
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.