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Query: [P] COG4521 ABC-type taurine transport system, periplasmic component, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFSKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQLast
1 -104.000[P] COG4521 ABC-type taurine transport system, periplasmic component  ali  100  1MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPAIIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFSKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ 320
2 -52.900[K] COG3888 Predicted transcriptional regulator  ali follow..  50RRTIGGKIKHVWLAEYYPYYDEKLLRIGCLRSTEYVKFVSVAKNYSESKGIDLIVRFYDDAISLMNDLSQGLLEFALAPIFTEIIYSISNRNSIILGAVASGG--------SGVYKNVNCNCGKILTSESSSMMILAREFAKTRKISEIAI---FKDPRRAIKDYESFKAEYIVIWEPYASKIMGEK----MASFSDVLDSFPCCGISVSENN--RENRTLIEIVRLYKRSRFTARE---------DVIDIFAKSTSVSPKTAKASLENYIW------DIKFYRSDLKKYLEFIGYPPIEEIIEKIYEEV.......... 327
3 -47.500[P] COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components  ali follow..  18  17AGASASAVFLKGCLSAEQAPEVTTVKLGYIPESAPLIIAKEKGFFAKYGLTNVELSKQASWGSARDNVEIGSAGGGIDGTEGLITKGNQKIPMYVLCQLITHGNGIAIALASAKSLFSKLKASTAAQTFAVNQDFWIRYWLAAGGIDPDDVKLLTVPSAQTVANMKTGTMDAFSTGDPWPFRIVKDKVGFMAALTAEIWKNHPEEYLAMRSDWVDQHPKATKALLKGLMEAQQWCDNFDNR--KELAEIVAARAYFNVPVDVLIDPYMGKYDMGEGRQIDDRSMPYKSHDLWFITESVRWGFLPKDYIDIDKVNREDIWK 409
4 -22.500[P] COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen  ali follow..  16  15LTIAAAASTLILAGCGEKAVDNNKVKIGVMAGAEAQVAEVAAKVAKEKYNLDVELVTFTDYVTPNAALDDGSIDANAFQHKPYLDKQIADRGYKLAIVGNTFVYPIAGYSKQ-IKSVDELQGARIAVPNDPTNLGRSLLLLQQQGLNPKKLEILELDAAQLPRSL--DDVALSIINTTYASSINLTPEKDGIFVENK--ESPYVNILVAREA--NVNAENVQNFKKAYQT.......................................................................................... 256
5 -21.300[P] COG3221 ABC-type phosphate/phosphonate transport system, periplasmic component  ali follow..  15  11AAGLSALALASCSGKSDAPAANNEVTFSILSTESTQNMESYLKDMEKQTGLKVKPFFSSNYSSLIVAMGAKQTDLGWFSNQSGLEAVRRSNGEVFARTFDPSGTDSVIIVPADIQSVQDLKSLDFGIGDKKSTSGTLAYVFIPANKKPETCFKTVINHQANLFAVANGKLDASTNNSTAIGLSKARGEGVTDKIRVWESPTLPEDPLVWRKDIDPVVKEKLRQFFLTYAQIGGFKPADDTHLLVVREMEATEQLGLAREAGDQAKVAAAQKVLDGVKAERLAAEGKAGVVAQPAN......................... 341
6 -19.900[R] COG2358 TRAP-type uncharacterized transport system, periplasmic component  ali follow..  12  7FGLFTLAATVTFSTSVFAAPTFINILTGGTSGVYYPIGVGLSQIYGHDIGAKTSVQATKASVENLNLLQAGRGELALALGDSVADAWNGVKKLRAIGNTYPNYIQVVASQASGIKTLADLKGKRISVAPKSGTELNARAIFKAAGLSYEDGKVEYLPYAESVELIKNRQLDATLQ-MAAIRDLASTMPITFVAIPADVVAKIDSPAYHAASIPAGTYDGQEQDVPTVAIDNILVSHSGVSD-----ELAYQMTKLMFDNLPRLVTAHAAAKDIALDKAAKNLPIPL----PGAERFYKEKGVLPE............... 319
7 -18.900[E] COG2113 ABC-type proline/glycine betaine transport systems, periplasmic components  ali follow..  10  6TAMTAGLLMTIGVAAAAEPESCKTVRFSDVGWTDITSTTAVASTILEALGYAPQSKLLSI-PVTYASMKNKDIDVYLGDWQPSMEADRKPFDKSIEVIGPNLTGAKKYVADAGVKDISDLGRKIYGIEPGNNGNRMILDMINKGDFGLTGWELVESSEAEVERATKDDQWIVFLGWAPHPMNTRYQIDYLSGADAYFGPNYGGADITNIRAGYAQECPNVARFVTNLRFTLEMENEIMNGILNDGNDPKDAAADWLKAHPEAVAPWLEGVTTFDGAPAKEAVESALKS................................ 312
8 -18.700[R] COG1427 Predicted periplasmic solute-binding protein  ali follow..  16  1......................MTITVGEIKNAFPFFYYVDRNKLLEK-DCHF---LIQTPATLNREMKAGRIQVGPISSFAYAENVDEFVLMPNLSVSANGPVGSIFLYTK--RPLEELEGSRIALTTTSATSVHLLKILLKQYVGVN----VTYDEMDPSFDEMMQDHDGCLLIGDEAIVTSWREEVETYRYDLGEL--MTFAVFAVRKDAIARQRAILEELYTAFVLSKEKNRKEQYASM-----IGHIQKGMGGTTAFWNHYFSNLVY--------DFHTQQQKGLLLFYEKAYEEGFLPKPIESIKIWGDVR... 280
9 -18.700[R] COG2107 Predicted periplasmic solute-binding protein  ali follow..  15  1......................MKIRVAHTPDDAFMFYAMTHGKVDTWLEIEH---VIEDIETLNRKAFNAEYEVTAISAHAYALLDDKYRILSAGASVGDGYGPVVVAKSE-----ISLDGKRIAVPGRYTTANLLLKLA------VEDFEPVEMPFDRIIQAVLDEEVDAGLLIHEGQITYADYGLKCVLDLWD-----LPLGLNAIRRDL---SVEVQEEFLRAMRESIAFAIENPDEAIEYAMKYSRGLDR-ERAKRFAMMYVNDYTY--------NMPESVDAALKKLYEMAEAKGLIKMPKLDILRL....... 271
10 -18.500[ET] COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain  ali follow..  16  4LVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNSQGELVKRINTQCTFVENP--DALIPSLKAKKIDAIMSS-----LSITEKRQQEIAFTDKLYAADSRLVVAKNQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIVSYQ----GQDNIYSDLTAGRIDAAFQ................................................................................................................................................. 182
11 -17.300[Q] COG4663 TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component  ali follow..  12  13GGLGAAAASALAAPAIAQTNPKVTWRLTSSFPKSLDTIYGGAEVLSEATDGNFQIQVFAAGEQAADAAAAGTVEACHTGGIDLFNEFLGTQGLVGYPGGN-TGVQMGGWFRKEIKTVADMKGLKMRVG-------FAGKVMERLGVVP-----QQLAGGDIYPALEKGTIDAAEWVGPYDDEKLGFYKVAPYYYYPGWWEGGPTVHAMFNKAAFDGLPKAYQSLLRTACQATDANMLQKYDYLNPSAIKRLVAAGAKL------SPFSPEILSACFDESNKVYAEMEASNAPFKKIWESIKAFRAEYFLNAQIAEYNYDT 357
12 -14.000[M] COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)  ali follow..  14  3ISKLWVSSLALLATVSLPLQAASPVTVGSKIDTEGALLGNMILQVLESHGVKTVNKIQLGTTPVVGAITAGELDI-YTGNGAFFFKDENDPAWKVWLTPAPANNTWTIAIRQKLSSLADLSKEGGTFKLAASAEFILPAFEKAYDFTLNQNQLLSLAGGDTAAAQQTSGVNAAMAYG--TDGPVAALGLQTLSDPKGVQPIYAP-APVVRESVLQAYPQIADWLVFASLDEKTLQQLNARIAVEGLDAKKVAAD.................................................................. 296
13 -13.400[G] COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component  ali follow..  13  6LTTTAIAFAVGAAAPAMAEFNSRNIRVSNGINQDHPVIKAMQACLDDKSGGKLKLTAFWGGAQATQALRSGVQEAVVTSSSPLVGLIPSLGVFDLPFLFANDKEADAVM-KHAVNKWEDFSGLKVRVMQNN----IFLDTFQNLGANA-----TPMAFGEVFSALETNAIDAQ---ENPYVTIDTSKFYEVQKYVTETNHAYTPFLFLFSKPIFDSYTPEEQTALRE--CAVVGRDEERKVIRELNQKSLEKIKAAGLEVNTLQTRIREKSMVVYEKHKAEIGADVVDAVLADLKKIRGQ.................... 335
14 -13.100[R] COG4588 Accessory colonization factor AcfC, contains ABC-type periplasmic domain  ali follow..  13  1...MKKIITLFGACALAFSMANADVNL-YGPGGPHTALKDIANKYSEKTGVKVNVNFGPQATWFEKAKKDADILFGASDQSALAIASDFGKDFNVSKIKPLYFREAIILTQKGIKGLKDLANKKVGKSNTSGTGVWEDMIGRTQDIKRNNIVAFVPNSGSARKLFAQDQADAWITWIDWSKSNPDIGTAVAIEKDLV----VYRTFNVIAKE---GASKETQDFIA.............................................................................................. 232
15 -11.000[P] COG1840 ABC-type Fe3+ transport system, periplasmic component  ali follow..  11  20MRLTIISSLLLAGTTLLGVPAHAAGDLNLICAADVVICEQMKGDFEKTHDIKVNMVRMSSGEAYAKIRAEARTDLWWAGTGDPHLQAASYAGALGWGYNTDIFKKKGYKEPKCWADLLALKGE-IQIASSGTAYTALASLVQIMGEDQGNISQYTKSGSAPVKAAARGETAVGIVFMHDAVAQTAEGFPVKSVAPCEGTGYEIGSMSIVKG---ARNLENAKTWY-------DWALQPDVQSRMKDAKSFQLPSNKTAEIPKEAPRFEDIKLINYDFKTYGDPEKRKALLERWDKDVGAAA................... 359
16 -10.900[M] COG4623 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein  ali follow..  11  28............................................FADYLGVKLKVTVRQNISQLFDDLDNGNADLLAAG-----LVYNSERVKNYQPGPTYYSVSQQLVYKVGPRTLGNLTAEQLTVAPGHVVVNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIA................................................................................................................................................. 156
17 -10.600[H] COG4143 ABC-type thiamine transport system, periplasmic component  ali follow..  15  1.MLKKYLPLLLLCAAPAFAKPVLTVYTYDSFAADWGPGPAVKKAFEADCNCELKLVALEDGVSLLNRLRMEGADVVLGLDNNLLEAATQTKLFAKSGVANEAVGYFAFVYDKSKKSLKELKWR-VIYQTSTPGLGLLLWMRKVYGLAAKTVTVTK-GWSEAYGLFLKGESDLVLSYSPAYHIIEEKKDNYAAANFSEGHYLQVEVAARTVA---SKQPELAEKFLK.............................................................................................. 264
18 -9.670[P] COG1613 ABC-type sulfate transport system, periplasmic component  ali follow..  11  9IVKLALVVGSLQLGSIGLALADTTILN-VSYDPTRELYKEFNAAFAEKWTVTIQTSHGGSGKQARSVIDGLEADVVTLALEADIDAIAKESGKIPADWKSRFESTIVFLVRKGIKDWGDLVREDTPNPKTSGGARWNFLAAWAWALFKHVPVLDTGARGATTTFVQRGLGDVLLAWENEAYLSLEELGPDNFDIVTPSISIKAEPPVALVDGNVDGTRKVAEAYLD---------------YLYSDVGQKIAAK.................................................................. 286
19 -9.530[H] COG2998 ABC-type tungstate transport system, permease component  ali follow..  13  8TTFTLAAASLILVSYSASSADDARIRLATTTSTYDSGLLDYLPKFEQDTGYKVDVIATGTG-KALKMGENGDVDLVMTHAPKAEASFVEA--VVVGPESDPAKIADEKNIAKVFENIAKSGAVFISRGDDSGTHKKELGIWAQNKIEPNFGGYRSIGQGMGPTLNMASEMQAYTLTD--WLAYNNKLALKILFEGDEQLFNPYQVIIVNPERYPTTQYHAAKVFSD---------------WLVNPKGQQLINE.................................................................. 259
20 -9.320[E] COG0687 Spermidine/putrescine-binding periplasmic protein  ali follow..  15  6GKTLLALTLAGSVAGMAQAADNKVLHVYNWSDYIAPDTLEK---FTKETGIKVVYDVYDSNEVLEAKLLAGKYDVVVPSNSFLAKQIKAGVYQKL-IGYNPDKVKAAFGDNAPVDSWDLVKLKQCGVSFLDSPTEILPAALHYLGYKPDTDNPKELKAAKYISDLANGNICVAIGYSGDIYQAKSRAEEAKNKVTVKEGAGSFFDMVAIPKD--AENTEGALAFVNFLMK--------PEIMAEITDVVQFPNGNAAATPLVSEAIRNDPGIYPSEEVMKKL...................................... 342
21 -9.290[P] COG4150 ABC-type sulfate transport system, periplasmic component  ali follow..  11  11RNGLTHIALFSALILSGVTASATELLNSSYDVSRELF-GFQAQWEQQNPGDKLTIKSHAGSSKQALAILQGKADVVTYNQITDVQILHDRGNLIPADWQARLPNNSAFLVRKGIRNWDDLVREDVKLPKTSGNGRYTYLAAWGATFLKNVEVFDTGGRGATTTFVERGLGDVLISFEVNNIRKEYGSDQYEVIVPPVDILAEFPVAWVDKNVEKNGTEKAAKAYLN---------------YLYSPPAQQVITRFNYRVYD--KAAMEAAKSQFPDTKLFRVEDQFGSWPQVMSTHFTTGGVLDKLLAEGHQ........ 345
22 -9.170[R] COG4134 ABC-type uncharacterized transport system, periplasmic component  ali follow..  12  12LSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDTAIYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTGSVDLLWVNGENFRTLKEANLLQTD-AESPWGGAQLTFIARRDVQTPQALPGTTYPRPPDFTGTAFLEQLLIMLTPDPAALKDFPPSPARMDALLKAGTFRLSLTFNPHAQQKIASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAXKVVANFLL--------SPDAQLRKADPAVWGDPSVLDPQKLPDGQRETLQSRMPQDLPPVLAEPHAGWVNALEQEWLHR.................... 385

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.