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Query: [S] COG4530 Uncharacterized protein conserved in bacteria, from VFDB

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAKPELGTKRIDPETGRKFYDLNRDPIVSPYTGKSYPLSFFEETSVAKVLEKEEEEDVKEVDTENTEVELVSLEEADDEASGGDDLPDLGDDDVEIEGDDDDTFLQTDDEDDDDDMSDIIGVSDEDDDVLast
1 -42.900[S] COG4530 Uncharacterized protein conserved in bacteria  ali  100  1MAKPELGTKRIDPETGRKFYDLNRDPIVSPYTGKSYPLSFFEETSVAKVLEKEEEEDVKEVDTENTEVELVSLEEADDEASGGDDLPDLGDDDVEIEGDDDDTFLQTDDEDDDDDMSDIIGVSDEDDDV 129
2 -11.900[S] COG5349 Uncharacterized protein conserved in bacteria  ali follow..  22  1MADAS-GLKCCCPRCGKLFQGFLKLAPACDQCGLDYGFAD......................................................................................... 51
3 -11.800[S] COG5604 Uncharacterized conserved protein  ali follow..  9  1MVKLSSIIKAR-----KANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQ. 123
4 -11.800[J] KOG2256 Predicted protein involved in nuclear export of pre-ribosomes  ali follow..  9  1MVKLSSIIKAR-----KANALAKKNDKIKKKDTDKGIRQKHSKKEGKDETLKRDVEKFIQNVNSEDTPSEDDSMSMDAFLEGGFEELDSANSNDAGSSRKRKNLPNENTQDSTSESSEEEEDGLESYQ. 123
5 -11.300[S] KOG2846 Predicted membrane protein  ali follow..  10  267..........ICKACHAH--EYEYTTFRCAFCNVLNPARKKRPVAPRLSLEAPSDTANKRNDSSESESSDDDSDKEPSARRALLQKLPSGGADMDATAETEDLAMETETIETGSAAPSTAEVAASS... 387
6 -11.000[J] COG5593 Nucleic-acid-binding protein possibly involved in ribosomal biogenesis  ali follow..  15  731................................................VDSKPQLEMDEEESDFDSEEMDKAMTDMGSDSEQSADENDNESMASEEKPMFSDEENLSEIAHSEDEFDDTVDFFEDEND. 810
7 -10.800[J] KOG4080 Mitochondrial ribosomal protein L32  ali follow..  9  94..........SCLQCG----HDHEMGVLCPFCYQKVLKETELMQSKIQETLGLDPVDKEVIVLYEGEKAEQSTDDLKNKRIVEMKKPRPMWFTKNLLQKSTQQLSETKEVKPSD............... 193
8 -10.600[S] COG5291 Predicted membrane protein  ali follow..  13  260.........................................TKSSTENSAVTEESQCCAESFKDSSVVSSQKSMAVSTVVGSSTEAKNNYLDFTEALCDKEVVAEQNPESQSNEEWDEKWGDSDNESE. 346
9 -10.600[R] COG3364 Zn-ribbon containing protein  ali follow..  14  1MITGEL-MPHRCTRCGTIFEDGDSVIL-CPNCGWNKFLYVKKEPEGLENQGRPALEEQKLDLEASLDEVVRNIDEALASGEEDREQQSENESKTDEERVES............................ 101
10 -10.500[K] KOG2473 RNA polymerase III transcription factor (TF)IIIC subunit  ali follow..  10  454....................................EKDDDVNADEDSEDLDDEYEEAANDDDISISSHGYGDMENNSRTYLQGLFNRFPSSASALYGSANDDNDSDGEYPIYEQESNALDDDEEDDE. 545
11 -10.400[R] COG5516 Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding  ali follow..  19  132IAGPERERLKICPNCAWLFLDRSRN---CDMCGNRTKARRHYRRSREEPKP.............................................................................. 186
12 -10.100[K] KOG2478 Putative RNA polymerase II regulator  ali follow..  10  446..........................................AARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD. 531
13 -9.910[DV] KOG4537 Zn-ribbon-containing protein implicated in mitosis  ali follow..  9  36......GLDEYCPTCSGILMEDRALVRRCVTCELFREKSSVIVGEVSLQDEDLNEAVNNKIPTPAAPVNKPAKKAVLQKSAPAKKKEAVPAAAEPSSSDT............................. 132
14 -9.900[S] KOG3817 Uncharacterized conserved protein  ali follow..  13  319LTQEEY-EQQTAVETSKSLADL-RKYVNSPECKQWAVMGKLRDPLRFASFANGAPHLDDEEIEDHSRTIEESMDAAPEEESVEEPEEDKPAELLPLPNSQQAARNSEPEPESESDDSEEEEFFEQEVDL 449
15 -9.870[S] COG4323 Predicted membrane protein  ali follow..  9  1MTRPLRWWKRACPGAALR--DVNAFPP--PSLAKLSAVFTIRRQPELDRRPQGASAGGALQALIAALPFALRPSRLSRQAKRPWTRACRRRLPATVGAGSLAAMDSAQPNTAAARYKSFAA........ 118
16 -9.820[R] COG1645 Uncharacterized Zn-finger containing protein  ali follow..  12  30......GLAEHCKVCGAPKFR-YQGTVICPICDVREEGEETPAPEPAAEVQVPEARSSPERDRPSPEQDRSSPERGRVPAERDRSSSETRKKIQARRPKTRFGQKAPETEGEED............... 139
17 -9.790[R] KOG4547 WD40 repeat-containing protein  ali follow..  10  552......................................NKFKTLNYEAGDIHSSEPVVEEDEDDVEYNEELDDAGLIEDGEESYGSEEEEEGDSDNEEEQKHTSSKQDGRLETEQSDGEEEAGYSDVEM 642
18 -9.680[J] KOG3475 60S ribosomal protein L37  ali follow..  21  1MTKSSFGKRHLCRRCGRSSYHIQKS--TCAQCG................................................................................................ 38
19 -9.670[K] KOG1597 Transcription initiation factor TFIIB  ali follow..  15  2.......SDAFCSDCKRHVFDHSAGDTVCSECGLVLESHSIDETSEWRTFANESGDNDPV..................................................................... 57
20 -9.630[KLB] COG5165 Nucleosome-binding factor SPN, POB3 subunit  ali follow..  11  429.............STSSRTFDLE---VVLRSNRGSTTFANISKEERVKNEDREVQERLQTALGSDSDEEDINMGSAGEDDESVDEDFQVSSDNDADEVAEEFDSDAALSDAEGGSDEERPSKKPKVE.. 552
21 -9.610[S] COG4306 Uncharacterized protein conserved in bacteria  ali follow..  11  32...SHSGEALQYPKCSASI---YEPPTFCNNCGSRFPWAERKIAGTVELVEAGTDLTPDEVQQFRTDLTQLTKDSPKTQVTCLR............................................. 126
22 -9.570[KLB] COG5406 Nucleosome binding factor SPN, SPT16 subunit  ali follow..  18  935..........................................................PSDDEGDDSVEEVSEYEASDADPSDEEEEESEEYSEDASEEDGYSESEVEDEESGEDWDELERKARQEDA. 1004
23 -9.470[K] KOG2857 Predicted MYND Zn-finger protein/hormone receptor interactor  ali follow..  9  1MCPRA---TQTCEICEKV-Y-------KCPSCLVPYCSLGCFKIHKVCNLINNAETPCAKPSDPSSTEEKPVVQCEPWFESCSGFVAASPAKEVPVKRPEEANDVVEKTQQKASASSSEIREALKDEPL 121
24 -9.430[R] KOG2785 C2H2-type Zn-finger protein  ali follow..  12  2.......ATYTCITCRVAFYNLRRKATYCTVCSKKFASFNAYENHLKSRRHVELEKKAVQAVNRKVEMMNEKNLEKGLGVDSVDKDAMNAAIQQAIKAQPS............................ 141
25 -9.370[K] COG3357 Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon  ali follow..  16  63...........CNKCGYVFKS--KPPSRCPKCKSE.............................................................................................. 87
26 -9.270[R] KOG4334 Uncharacterized conserved protein, contains double-stranded RNA-binding motif and WW domain  ali follow..  9  2............................................EQESGGKKSNEQLLSEREAIMRQLAMLGSGPEDLDVDDEEEDEEEEVEKMEEGVEETMENASVVKETTPVKDENIVEDSNSSEE. 85
27 -9.160[J] COG2126 Ribosomal protein L37E  ali follow..  13  5...PSFGKMNRCRRCGRNAYNVSKH--YCAACGFGRTKKIRRYSWQNKKVNGVRIR......................................................................... 61
28 -9.160[R] KOG3183 Predicted Zn-finger protein  ali follow..  20  1MGTPEFGKH--CDYCKQ--IDF---PFTCDRCLQVY............................................................................................. 35
29 -9.160[K] KOG2907 RNA polymerase I transcription factor TFIIS, subunit A12.2/RPA12  ali follow..  13  5......GSLIFCLDCGDLLEAVLGSNVECSQCKAIYPKSQFSNLKVVTTTADDAFPSSLRAKKSVVKTSLKKNELKDGATIK............................................... 83
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;